Laxatives. pptx

1. Topic- Laxatives
Presented by
Hariom Jaiswal
Asst. Pro. D.PH 1st
Year
Pharmacognosy
Rajiv Gandhi College of Pharmacy Nautanwa Maharajganj
UP 273164

2. INTRODUCTION OF LAXATIVES
 Laxatives are drugs that relieve constipation by losing stools or inducing a bowel
movement.
 Some laxatives are also used before bowel procedures or examination.
 Laxatives come as pills, capsules, liquids, foods, gums, and suppositories.
 Drugs are
1. Aloe,
2. Castor oil,
3. Ispaghula
4. Senna

3. 1. ALOE
Synonym: Aloe, Alo-vera, Guar-
patha, Kumari, Ghrita-kumari
Biological Source: It consist of
dried juice of leaves of “Aloe
barbadensis Miller (एलो
बारबाडेन्सिस मिलर) and Aloe
Africana”.
Family: Liliaceae.

4. Morphological Characters:
Colour: Green colour
Odour: Odourless
Taste: Bitter taste
Size: It is available in various sizes.
Solubility: It is entirely soluble in 60% alcohol
and it partially soluble in water.

5. Chemical constituents:
1. Anthracene glycosides (11 to 40%).
2. Barbaloin or Aloin,
3. Isobarbaloin,
4. aloe-emodin and aloesone.
5. Aloinosides A and B
6. Resins
7. Also contains Aloetic acid,etc.

6. Uses:
1. It is used as Purgative.
2. It is used as Laxative
3. It is used as Used for Ulcers and burns
4. Aloe found many uses in cosmetics now a days like,
• Hair conditioner
• Hand and body lotion
• Moisture base cleaner
• Shampoo and facewash

7. 2. CASTOR OIL
Synonyms: Ricinus oil, Oleum ricini.
Biological source: Castor oil is a fixed
oil obtained by cold expression of the
seeds of “Ricinus Communis”(रिकिनस
कम्युनिस).
Family: Euphorbiaceae
(यूफोरबियासी.).

8. MORPHOLOGICAL CHARACTERS:
Colour: Pale yellow or colourless liquid.
Odour: Slight bitter
Taste: Tasteless.
CHEMICAL CONSTITUENTS:
1. Castor oil contains triglyceride of Ricinoleic acid
80%.
2. Iso-ricinolei
3. linoleic , stearic and isostearic acid.
4. It contains heptaldehyde, sebacic acid

9. USES:
1. Castor oil is used as cathartic.
2. It is used as laxative,
3. lubricant in paints
4. It is used grease, polish, printing ink,
5. It is used aromatic castor oil, or in the form of
capsules,
6. It is used in cosmetic product like- creams, jellies,
lipsticks, perfumed hair oil, soap etc.
7. also used as hair tonic.

10. SENNA LEAF
Synonyms:-Tinnevelly Senna, Indian
Senna, Senai ki patti, Sonamukhi
Biological source:- It consist of dried
leaflets of Cassia angustifolia. (कैसिया
अन्गुस्टिफोलिया.)
Family:- Leguminosae. (लेग्यूमिनोसी)

11. Morphological Characters:
Colour: Green colour
Odour: Odourless
Taste: Bitter taste
Size: 2.5-5.0 cm long and 7-9 mm wide
Chemical Constituents:-
1. It consists not less than 2.0% of hydroxy anthracene
2. It consists Sennoside-A, Sennoside-B, Sennoside-C, and
Sennoside -D.

12. Used
1. It is used as laxatives
2. It is used as Purgative.

13. ISAPGOL
Synonyms: Plantage seed, Psyllium husk,
Ashwakarna, Isapgol, Isabgol, Indian Psyllium
Biological Source: It consist of dried seeds of
the plant Plantego Ovata Forsk (प्लांटेगो ओवाटा
फ़ोर्स्क)
Family: Plantagenaceae (प्लांटैजेनेसी)

14. Morphological Characters:
Colour: Pinkish- grey to brown
Odour: Odourless
Taste: Tasteless
Size: 1-3.5 mm long and 1- 1.75 mm wide
Chemical Constituents:-
1. Mucilage 10%
2. Carbohydrates.
3. Fixed Oil
4. Protein

15. Used
1. It is used as Demulcent.
2. It is used as laxative
3. It is used as coating material
4. It is used as binding agent.

16. THANK
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