This document discusses the energy benefits of integrating air conditioning, medium temperature, and low temperature refrigeration systems in supermarkets using water-cooled two-stage transcritical CO2 systems. Key points include: 1) Such systems can reduce energy consumption for refrigeration, AC, and heating by 45% on average in US supermarkets, representing a 29% reduction in total store energy use. 2) There would be a 67% reduction in total emissions and a 33.5% reduction in annual operating costs, saving around $80,000 per year for the average US supermarket. 3) Evaporative gas coolers allow subcritical CO2 operation in most climates worldwide and achieve high performance with