This document discusses different types of organ donors and kidney preservation techniques. It describes donor types including donation after brain death (DBD), standard criteria donors (SCD), and expanded criteria donors (ECD). It also describes donation after circulatory death (DCD) and categories of DCD donors. Regarding kidney preservation, it discusses static cold storage, hypothermic machine perfusion, and normothermic perfusion techniques. It notes the metabolic problems that can occur after circulatory arrest and the benefits of perfusion techniques in addressing these issues.

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5. • DBD- donation after brain death.
• Usually young people having irreversible brain
damage
SCD
(STANDARD CRITERIA DONOR)
• >60 years old or
• 50-59 years old with (2/3)
• Cerebrovascular cause of death
• S. Cr. > 1.5 mg/dL
• HTN
ECD
(EXPANDED CRITERIA DONOR)
• Suffered brain injury but not met criteria for brain
death
• Controlled DCD (Maastricht category 3)
• Uncontrolled DCD(Maastricht category 1&2)
DCD (DONATION
AFTER CIRCULATORY DEATH)

6. CATEGORY DESCRIPTION Brain Warm
ischemia
time
1(uncontrolled
DCD)
Dead on arrival at the hospital no long
2(uncontrolled
DCD)
Unsuccessful resuscitation at the
hospital
no long
3(controlled
DCD)
Withdrawal of the supportive
treatment
yes short
4 Cardiac arrest following
establishment of brain death
yes

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8. DONOR KIDNEY
PRESERVATION
STATIC
HYPOTHERMIC
MACHINE
PERFUSION
HYPOTHERMIC NORMOTHERMIC

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11. Circulatory arrest
Continuing tissue
metabolism in absence
of O2 and nutrients
Major metabolic
problems

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35. • (NRP)
• (NMP)
• (NRC)

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