This lecture describes the pathology of stroke, the types of stroke, gross morphology and microscopic changes in stroke, transient ischemic attack, ischemic stroke, hemorrhagic stroke, etiopathogenesis of stroke and infarcts of stroke.
BRONCHIECTASIS PATHOLOGY FOR NURSES.pptxSaili Gaude
This lecture describes in detail the pathology of Bronchiectasis . The lecture is prepared for sem 3 nursing students. It includes types of bronchiectasis , its types, etiopathogenesis, gross morphology an dmicroscopic morphology.
Hydrocephalus, meningitis and encephalitis - PathologySaili Gaude
This presentation covers in brief the CNS pathology for nurses according to sem 4 syllabus. This covers disorders such as meningitis, encephalitis and also includes hydrocephalus.
Pneumonia is the inflammation of the lung parenchyma. This lecture deals with pathology of pneumonia in short and concise manner for nursing students. It includes the types of pneumonia, lobar pneumonia, bronchial pneumonia, interstitial pneumonia , hospital acquired pneumonia, community acquired pneumonia and so on. It also discusses the stages of pneumonia that is initial response, red hepatization, grey hepatization and resolution
ASTHMA - PATHOLOGY FOR NURSING STUDENTSSaili Gaude
This lecture is on Pathology of asthma for nurses. This lecture is prepared for sem 4 nursing students. It includes, etiopathogenesis, gross morphology and microscopic morphology and diagnosis of asthma. It describes charcot leyden crystals and Cruschman spiral.
Otosclerosis is the overgrowth of the spongy bones in the bones of the middle ear leading to the fixation of the bones causing conductive hearing loss in patient.
This lecture includes its pathophysiology, causes, risk factors, symptoms and treatment
PATHOLOGY OF URINARY SYSTEM DISORDER pptSaili Gaude
This lecture includes pathology of renal calculi , renal carcinoma, bladder carcinoma, bladder tumor, renal tumor etc. This lecture have been prepared in view of Nursing students according to syllabus.
BRONCHIECTASIS PATHOLOGY FOR NURSES.pptxSaili Gaude
This lecture describes in detail the pathology of Bronchiectasis . The lecture is prepared for sem 3 nursing students. It includes types of bronchiectasis , its types, etiopathogenesis, gross morphology an dmicroscopic morphology.
Hydrocephalus, meningitis and encephalitis - PathologySaili Gaude
This presentation covers in brief the CNS pathology for nurses according to sem 4 syllabus. This covers disorders such as meningitis, encephalitis and also includes hydrocephalus.
Pneumonia is the inflammation of the lung parenchyma. This lecture deals with pathology of pneumonia in short and concise manner for nursing students. It includes the types of pneumonia, lobar pneumonia, bronchial pneumonia, interstitial pneumonia , hospital acquired pneumonia, community acquired pneumonia and so on. It also discusses the stages of pneumonia that is initial response, red hepatization, grey hepatization and resolution
ASTHMA - PATHOLOGY FOR NURSING STUDENTSSaili Gaude
This lecture is on Pathology of asthma for nurses. This lecture is prepared for sem 4 nursing students. It includes, etiopathogenesis, gross morphology and microscopic morphology and diagnosis of asthma. It describes charcot leyden crystals and Cruschman spiral.
Otosclerosis is the overgrowth of the spongy bones in the bones of the middle ear leading to the fixation of the bones causing conductive hearing loss in patient.
This lecture includes its pathophysiology, causes, risk factors, symptoms and treatment
PATHOLOGY OF URINARY SYSTEM DISORDER pptSaili Gaude
This lecture includes pathology of renal calculi , renal carcinoma, bladder carcinoma, bladder tumor, renal tumor etc. This lecture have been prepared in view of Nursing students according to syllabus.
meniere disease is the inner ear condition which affect the patient haring and balance this ppt can help the nurses to take care of the patient affected with this disease and can be used as a study material for their examination
short and concise notes as well as presentation on Inheritance, laws of inheritance, patterns of inheritance and mutation for nurses. Subject :Genetics ,Unit: I.
cerebrovascular accident, commonly known as stroke is one of the most common health problems of the world. in the developing world, its increasing incidence is a matter of concern among the health workers across the globe. thus adequate knowledge about this medical condition is a must to deal with it effectively.
Otitis media is a group of inflammatory diseases of the middle ear. The two main types are acute otitis media (AOM) and otitis media with effusion (OME). AOM is an infection of rapid onset that usually presents with ear pain.
Ototoxicity is, quite simply, ear poisoning (oto = ear, toxicity = poisoning), which results from exposure to drugs or chemicals that damage the inner ear or the vestibulo-cochlear nerve (the nerve sending balance and hearing information from the inner ear to the brain).
Normally, the pleural space contains a small amount of fluid (5 to 15 mL), which acts as a lubricant that allows the pleural surfaces to move without friction.
But if fluid builds up from either increased production or inadequate removal pleural effusion results.
Pleural effusion B/L or unilateral (parapneumonic process)
Refers to any significant collection of fluid within pleural space.
Any imbalance in formation, absorption lead accumulation of pleural fluid. Common condition:
CHF
Bacterial pneumonia
Malignancy(chest tumor)
Pulmonary embolism
Pleura effusion is a condition refers to a collection of fluid in the pleural space. It is almost secondary to other conditions.
meniere disease is the inner ear condition which affect the patient haring and balance this ppt can help the nurses to take care of the patient affected with this disease and can be used as a study material for their examination
short and concise notes as well as presentation on Inheritance, laws of inheritance, patterns of inheritance and mutation for nurses. Subject :Genetics ,Unit: I.
cerebrovascular accident, commonly known as stroke is one of the most common health problems of the world. in the developing world, its increasing incidence is a matter of concern among the health workers across the globe. thus adequate knowledge about this medical condition is a must to deal with it effectively.
Otitis media is a group of inflammatory diseases of the middle ear. The two main types are acute otitis media (AOM) and otitis media with effusion (OME). AOM is an infection of rapid onset that usually presents with ear pain.
Ototoxicity is, quite simply, ear poisoning (oto = ear, toxicity = poisoning), which results from exposure to drugs or chemicals that damage the inner ear or the vestibulo-cochlear nerve (the nerve sending balance and hearing information from the inner ear to the brain).
Normally, the pleural space contains a small amount of fluid (5 to 15 mL), which acts as a lubricant that allows the pleural surfaces to move without friction.
But if fluid builds up from either increased production or inadequate removal pleural effusion results.
Pleural effusion B/L or unilateral (parapneumonic process)
Refers to any significant collection of fluid within pleural space.
Any imbalance in formation, absorption lead accumulation of pleural fluid. Common condition:
CHF
Bacterial pneumonia
Malignancy(chest tumor)
Pulmonary embolism
Pleura effusion is a condition refers to a collection of fluid in the pleural space. It is almost secondary to other conditions.
ANATOMY OF BLOOD- RBCs, WBCs & PlateletSaili Gaude
This lecture involves, anatomy of RBC, WBC and platelets. It includes detailed description of this cells, its functions and hematopoeisis in short. This lecture is prepared for BSc nursing students.
Anatomy of Heart- Internal structures ptSaili Gaude
This lecture consists of the anatomy of heart, layers, its valves and conduction system. It also includes coronary circulation and venous supply of heart.
OXYGENATION - TYPES OF OXYGEN DEVICE.pptSaili Gaude
This is short yet comprehensive lecture on oxygenation for Bsc nursing students. This lecture comprises of various devices of oxygen administration and their uses, advantages and disadvantages.
ANATOMY AND PHYSIOLOGY OF PANCREAS PPTX.Saili Gaude
This lecture includes the anatomy of pancreas, structure of pancreas, parts of pancreas, its enzymes, trypsin, proteas and lipase and amylase, its functions, common bile duct, ucinate process, location of pancreas, pancreatic acinar cells, islet of langerhans and physiology of pancreas
This lecture deals with anatomy of liver and physiology of liver. It includes the lobes of liver, structure of liver, location of liver, porta hepatis, the lobules and hepatocytes, kuffer cells, glissons capsule, biliary sytem, portal artery, portal triad, portal vein, functions of liver.
This lecture describes anatomy of gall bladder and physiology of gall bladder. It includes parts of gall bladder, layers of gall bladder, bile, biliary system, bile duct, functions of gall bladder, functions of bile, blood supply of gall bladder etc.
ANATOMY OF SMALL INTESTINE -presentationSaili Gaude
It includes the parts of small intestine and large intestine. Includes its layers, mucosa, submucosa, muscularis and serosa. discussed also is duodenum, jejunum and ileum. and Cecum, ascending colon, descending colon , transverse colon, descending colon and sigmoid colon. Also includes its functions, sphincters and blood and nerve supply
ANATOMY OF STOMACH- a short concise lectSaili Gaude
It describes anatomy of stomach in short. Includes layers of stomach, 2 sphincters, the parts of stomach, Its functions and location with its blood vessels and nerve supply
Anatomy of Esophagus for nursing studentSaili Gaude
It describes the anatomy of esophagus. it includes the parts of esophagus, layers, sphincters , junctions of esophagus, blood supply of esophagus and its functions
Anatomy and physiology of skin. Explanation on epidermis, dermis and hypodermis. The various mechanoreceptors, pigments and glands of skin. Physiologic function of the skin
A short simplified anatomy of eye. it includes explanation of all 3 layers of eyes, sclera, choroid and retina. Anatomy of cornea, conjunctiva, pupil, lens, iris, ciliary body etc. physiology of vision, its process and photochemical activity of eyes are discussed in detail.
It describe the anatomy of eye in detail according to the BD chaurasia textbook.
It includes the parts of eye, internal structures, blood and nerve supply.
temperature, types of thermometers, sites for temperature taking, fever, types of fever, pulse, alterations in pulse, respirations, alterations in respiration,blood pressure, alterations in blood pressure, pulse oximeter.
hours alloted: 15 hrs.
Unit III- Nursing as a profession part 1. Includes defintion, characteristics,scope , functions, qualities and categories of nurse. Also included is a brief history of nursing field.
Hospital, types, organization & functionSaili Gaude
Class: First year BSc Nursing
Subject: Fundamentals of nursing
Unit : I - Introduction
Brief lecture on hospital, its types, functions and organization.
Hours distributed: 1 hour
micro teaching on communication m.sc nursing.pdfAnurag Sharma
Microteaching is a unique model of practice teaching. It is a viable instrument for the. desired change in the teaching behavior or the behavior potential which, in specified types of real. classroom situations, tends to facilitate the achievement of specified types of objectives.
Anti ulcer drugs and their Advance pharmacology ||
Anti-ulcer drugs are medications used to prevent and treat ulcers in the stomach and upper part of the small intestine (duodenal ulcers). These ulcers are often caused by an imbalance between stomach acid and the mucosal lining, which protects the stomach lining.
||Scope: Overview of various classes of anti-ulcer drugs, their mechanisms of action, indications, side effects, and clinical considerations.
Tom Selleck Health: A Comprehensive Look at the Iconic Actor’s Wellness Journeygreendigital
Tom Selleck, an enduring figure in Hollywood. has captivated audiences for decades with his rugged charm, iconic moustache. and memorable roles in television and film. From his breakout role as Thomas Magnum in Magnum P.I. to his current portrayal of Frank Reagan in Blue Bloods. Selleck's career has spanned over 50 years. But beyond his professional achievements. fans have often been curious about Tom Selleck Health. especially as he has aged in the public eye.
Follow us on: Pinterest
Introduction
Many have been interested in Tom Selleck health. not only because of his enduring presence on screen but also because of the challenges. and lifestyle choices he has faced and made over the years. This article delves into the various aspects of Tom Selleck health. exploring his fitness regimen, diet, mental health. and the challenges he has encountered as he ages. We'll look at how he maintains his well-being. the health issues he has faced, and his approach to ageing .
Early Life and Career
Childhood and Athletic Beginnings
Tom Selleck was born on January 29, 1945, in Detroit, Michigan, and grew up in Sherman Oaks, California. From an early age, he was involved in sports, particularly basketball. which played a significant role in his physical development. His athletic pursuits continued into college. where he attended the University of Southern California (USC) on a basketball scholarship. This early involvement in sports laid a strong foundation for his physical health and disciplined lifestyle.
Transition to Acting
Selleck's transition from an athlete to an actor came with its physical demands. His first significant role in "Magnum P.I." required him to perform various stunts and maintain a fit appearance. This role, which he played from 1980 to 1988. necessitated a rigorous fitness routine to meet the show's demands. setting the stage for his long-term commitment to health and wellness.
Fitness Regimen
Workout Routine
Tom Selleck health and fitness regimen has evolved. adapting to his changing roles and age. During his "Magnum, P.I." days. Selleck's workouts were intense and focused on building and maintaining muscle mass. His routine included weightlifting, cardiovascular exercises. and specific training for the stunts he performed on the show.
Selleck adjusted his fitness routine as he aged to suit his body's needs. Today, his workouts focus on maintaining flexibility, strength, and cardiovascular health. He incorporates low-impact exercises such as swimming, walking, and light weightlifting. This balanced approach helps him stay fit without putting undue strain on his joints and muscles.
Importance of Flexibility and Mobility
In recent years, Selleck has emphasized the importance of flexibility and mobility in his fitness regimen. Understanding the natural decline in muscle mass and joint flexibility with age. he includes stretching and yoga in his routine. These practices help prevent injuries, improve posture, and maintain mobilit
ARTIFICIAL INTELLIGENCE IN HEALTHCARE.pdfAnujkumaranit
Artificial intelligence (AI) refers to the simulation of human intelligence processes by machines, especially computer systems. It encompasses tasks such as learning, reasoning, problem-solving, perception, and language understanding. AI technologies are revolutionizing various fields, from healthcare to finance, by enabling machines to perform tasks that typically require human intelligence.
HOT NEW PRODUCT! BIG SALES FAST SHIPPING NOW FROM CHINA!! EU KU DB BK substit...GL Anaacs
Contact us if you are interested:
Email / Skype : kefaya1771@gmail.com
Threema: PXHY5PDH
New BATCH Ku !!! MUCH IN DEMAND FAST SALE EVERY BATCH HAPPY GOOD EFFECT BIG BATCH !
Contact me on Threema or skype to start big business!!
Hot-sale products:
NEW HOT EUTYLONE WHITE CRYSTAL!!
5cl-adba precursor (semi finished )
5cl-adba raw materials
ADBB precursor (semi finished )
ADBB raw materials
APVP powder
5fadb/4f-adb
Jwh018 / Jwh210
Eutylone crystal
Protonitazene (hydrochloride) CAS: 119276-01-6
Flubrotizolam CAS: 57801-95-3
Metonitazene CAS: 14680-51-4
Payment terms: Western Union,MoneyGram,Bitcoin or USDT.
Deliver Time: Usually 7-15days
Shipping method: FedEx, TNT, DHL,UPS etc.Our deliveries are 100% safe, fast, reliable and discreet.
Samples will be sent for your evaluation!If you are interested in, please contact me, let's talk details.
We specializes in exporting high quality Research chemical, medical intermediate, Pharmaceutical chemicals and so on. Products are exported to USA, Canada, France, Korea, Japan,Russia, Southeast Asia and other countries.
Lung Cancer: Artificial Intelligence, Synergetics, Complex System Analysis, S...Oleg Kshivets
RESULTS: Overall life span (LS) was 2252.1±1742.5 days and cumulative 5-year survival (5YS) reached 73.2%, 10 years – 64.8%, 20 years – 42.5%. 513 LCP lived more than 5 years (LS=3124.6±1525.6 days), 148 LCP – more than 10 years (LS=5054.4±1504.1 days).199 LCP died because of LC (LS=562.7±374.5 days). 5YS of LCP after bi/lobectomies was significantly superior in comparison with LCP after pneumonectomies (78.1% vs.63.7%, P=0.00001 by log-rank test). AT significantly improved 5YS (66.3% vs. 34.8%) (P=0.00000 by log-rank test) only for LCP with N1-2. Cox modeling displayed that 5YS of LCP significantly depended on: phase transition (PT) early-invasive LC in terms of synergetics, PT N0—N12, cell ratio factors (ratio between cancer cells- CC and blood cells subpopulations), G1-3, histology, glucose, AT, blood cell circuit, prothrombin index, heparin tolerance, recalcification time (P=0.000-0.038). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and PT early-invasive LC (rank=1), PT N0—N12 (rank=2), thrombocytes/CC (3), erythrocytes/CC (4), eosinophils/CC (5), healthy cells/CC (6), lymphocytes/CC (7), segmented neutrophils/CC (8), stick neutrophils/CC (9), monocytes/CC (10); leucocytes/CC (11). Correct prediction of 5YS was 100% by neural networks computing (area under ROC curve=1.0; error=0.0).
CONCLUSIONS: 5YS of LCP after radical procedures significantly depended on: 1) PT early-invasive cancer; 2) PT N0--N12; 3) cell ratio factors; 4) blood cell circuit; 5) biochemical factors; 6) hemostasis system; 7) AT; 8) LC characteristics; 9) LC cell dynamics; 10) surgery type: lobectomy/pneumonectomy; 11) anthropometric data. Optimal diagnosis and treatment strategies for LC are: 1) screening and early detection of LC; 2) availability of experienced thoracic surgeons because of complexity of radical procedures; 3) aggressive en block surgery and adequate lymph node dissection for completeness; 4) precise prediction; 5) adjuvant chemoimmunoradiotherapy for LCP with unfavorable prognosis.
These lecture slides, by Dr Sidra Arshad, offer a quick overview of physiological basis of a normal electrocardiogram.
Learning objectives:
1. Define an electrocardiogram (ECG) and electrocardiography
2. Describe how dipoles generated by the heart produce the waveforms of the ECG
3. Describe the components of a normal electrocardiogram of a typical bipolar leads (limb II)
4. Differentiate between intervals and segments
5. Enlist some common indications for obtaining an ECG
Study Resources:
1. Chapter 11, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 9, Human Physiology - From Cells to Systems, Lauralee Sherwood, 9th edition
3. Chapter 29, Ganong’s Review of Medical Physiology, 26th edition
4. Electrocardiogram, StatPearls - https://www.ncbi.nlm.nih.gov/books/NBK549803/
5. ECG in Medical Practice by ABM Abdullah, 4th edition
6. ECG Basics, http://www.nataliescasebook.com/tag/e-c-g-basics
Couples presenting to the infertility clinic- Do they really have infertility...Sujoy Dasgupta
Dr Sujoy Dasgupta presented the study on "Couples presenting to the infertility clinic- Do they really have infertility? – The unexplored stories of non-consummation" in the 13th Congress of the Asia Pacific Initiative on Reproduction (ASPIRE 2024) at Manila on 24 May, 2024.
Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
Ozempic: Preoperative Management of Patients on GLP-1 Receptor Agonists Saeid Safari
Preoperative Management of Patients on GLP-1 Receptor Agonists like Ozempic and Semiglutide
ASA GUIDELINE
NYSORA Guideline
2 Case Reports of Gastric Ultrasound
New Directions in Targeted Therapeutic Approaches for Older Adults With Mantl...i3 Health
i3 Health is pleased to make the speaker slides from this activity available for use as a non-accredited self-study or teaching resource.
This slide deck presented by Dr. Kami Maddocks, Professor-Clinical in the Division of Hematology and
Associate Division Director for Ambulatory Operations
The Ohio State University Comprehensive Cancer Center, will provide insight into new directions in targeted therapeutic approaches for older adults with mantle cell lymphoma.
STATEMENT OF NEED
Mantle cell lymphoma (MCL) is a rare, aggressive B-cell non-Hodgkin lymphoma (NHL) accounting for 5% to 7% of all lymphomas. Its prognosis ranges from indolent disease that does not require treatment for years to very aggressive disease, which is associated with poor survival (Silkenstedt et al, 2021). Typically, MCL is diagnosed at advanced stage and in older patients who cannot tolerate intensive therapy (NCCN, 2022). Although recent advances have slightly increased remission rates, recurrence and relapse remain very common, leading to a median overall survival between 3 and 6 years (LLS, 2021). Though there are several effective options, progress is still needed towards establishing an accepted frontline approach for MCL (Castellino et al, 2022). Treatment selection and management of MCL are complicated by the heterogeneity of prognosis, advanced age and comorbidities of patients, and lack of an established standard approach for treatment, making it vital that clinicians be familiar with the latest research and advances in this area. In this activity chaired by Michael Wang, MD, Professor in the Department of Lymphoma & Myeloma at MD Anderson Cancer Center, expert faculty will discuss prognostic factors informing treatment, the promising results of recent trials in new therapeutic approaches, and the implications of treatment resistance in therapeutic selection for MCL.
Target Audience
Hematology/oncology fellows, attending faculty, and other health care professionals involved in the treatment of patients with mantle cell lymphoma (MCL).
Learning Objectives
1.) Identify clinical and biological prognostic factors that can guide treatment decision making for older adults with MCL
2.) Evaluate emerging data on targeted therapeutic approaches for treatment-naive and relapsed/refractory MCL and their applicability to older adults
3.) Assess mechanisms of resistance to targeted therapies for MCL and their implications for treatment selection
These simplified slides by Dr. Sidra Arshad present an overview of the non-respiratory functions of the respiratory tract.
Learning objectives:
1. Enlist the non-respiratory functions of the respiratory tract
2. Briefly explain how these functions are carried out
3. Discuss the significance of dead space
4. Differentiate between minute ventilation and alveolar ventilation
5. Describe the cough and sneeze reflexes
Study Resources:
1. Chapter 39, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 34, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 17, Human Physiology by Lauralee Sherwood, 9th edition
4. Non-respiratory functions of the lungs https://academic.oup.com/bjaed/article/13/3/98/278874
4. 1)TRANSIENT ISCHEMICATTACK
• Describes patients whose symptoms lasts for few seconds or minutes and resolves
within 24 hours.
• Symptoms are due to transient temporary impairment of blood flow to a specific
part of the brain
• It is an indication that a complete stroke may take place soon
5. 2) PROGRESSING STROKE
• Also called stroke in evolution
• Where the symptoms of stroke worsen from time of stroke
• This may occur as a result of increase in size of infarction or hemorrhage
6. 2) COMPLETED STROKE
• Describes stroke where the focal hypoxic defect persists but does not progress any
further
7. PATHOLOGIC CHANGES
• 1) Hypoxic encephalopathy : diffuse hypoxia is
present. Patient may recover without damage
• 2) Cerebral Infarction : Localised area of tissue
necrosis due to occlusion of blood supply.
• 3) Red infarct – multiple petechial hemorrhage
is seen
• 4) Pale infarct – associated with ischemic injury
8. ETIPATHOGENESIS
• ISCHEMIC STROKE
• Large artery thrombosis
• Small artery thrombosis
• Cardiogenic embolic stroke
• Cryptogenic stroke (no cause)
• Cocaine use
• Coagulopathies
10. ISCHAEMIC STROKE
• Disruption of blood flow due to obstruction leads to
complex series of events called the ischemic cascade
• The ischemic cascade starts when the neurons can
no longer withstand O2 deprivation, membrane
pump that maintain electrolyte balance fails and
cells stop functioning
11. HEMMORHAGIC STROKE
• Pathologic changes depends on the type of cerebro vascular disease.
• Here normal brain metabolism is disrupted by the brain getting exposed to
blood due to hemorrhage
• It can occur due to :
• 1. Increased ICP
• 2. Secondary ischemia of the brain due to reduced perfusion pressure
• 3.Vasospasm of the blood vessels
12.
13. GROSS MORPHOLOGY
• Single or multiple small cavity like infarction are seen
• Lake like spaces 1.5 cm wide present in the white mater and grey mater
• Can be clinically silent or cause severe neurologic deficit
14. MICROSCOPIC
• Cavities with loss of tissues are scattered with fat laden macrophages surrounded
by gliosis
• Hemorrhage infarct have extravasation and resorption of blood
• Increased intracerebral hematomas