Dr. Erika Kunz discusses Clariant's innovative strategies in chemical hazard management and regulatory assessments, emphasizing the integration of in silico and alternative in vitro methods. The document highlights Clariant's contributions to the development of tools like AMBIT and its commitment to sustainability in the product lifecycle. It concludes with a call for broader acceptance of alternative assessment methods among regulators.

1. Public
Dr. Erika Kunz
Global Product Stewardship
Global Registration and Evaluation of Chemicals
09.06.2017
Speeding up chemical
assessments: from novel
information to new
management approaches,
what works?

2. Dr. Erika Kunz, Global Product Stewardship, Global Registration and Evaluation of Chemicals, 09.06.2017
CLARIANT: A GLOBALLY LEADING COMPANY IN
SPECIALTY CHEMICALS
Public, Speeding up chemical assessments: from novel information to new management approaches, what works?2

3. Dr. Erika Kunz, Global Product Stewardship, Global Registration and Evaluation of Chemicals, 09.06.2017
Clariant is using novel approaches to generate data
and manage chemical hazards and risks
Public, Speeding up chemical assessments: from novel information to new management approaches, what works?3
Clariant is key
initiator/contributor in Cefic LRI
to the development of Ambit.
Clariant combines Ambit with
several predictive tools
Novel approaches are part of our innovation roadmap in
Clariant’s “Idea to Market Process” as well as in the
systematic approach to sustainability of our products in
the “Portfolio Value Program” PVP
In silico for
regulatory
Innovation
portfolio
assessment
Clariant advocates for the
implementation of
alternative in vitro methods:
scientific publications, and
scientific discussions in
workshops in EU, Asia and
India
In vitro for
regulatory
innovation
portfolio
assessment

4. Dr. Erika Kunz, Global Product Stewardship, Global Registration and Evaluation of Chemicals, 09.06.2017
Strong focus on in silico approaches: Clariant is key
initiator/contributor in Cefic LRI to the development
of Ambit. Clariant combines Ambit with several
predictive tools
Public, Speeding up chemical assessments: from novel information to new management approaches, what works?4

5. Dr. Erika Kunz, Global Product Stewardship, Global Registration and Evaluation of Chemicals, 09.06.2017
Clariant advocates for alternative in vitro methods:
scientific publications, and scientific discussions in
workshops in EU, Asia and India
Public, Speeding up chemical assessments: from novel information to new management approaches, what works?5
Chemical Weekly

6. Dr. Erika Kunz, Global Product Stewardship, Global Registration and Evaluation of Chemicals, 09.06.2017
Novel approaches are part of the innovation
roadmap: Clariant’s Idea to Market Process
INTEGRATION OF SUSTAINABILITY AND PRODUCT STEWARDSHIP IN THE INNOVATION PROCESS
AMBIT - COMPTOX
SUITE
Toxicology prediction
Identification of
toxicological
showstoppers
PORTFOLIO VALUE PROGRAM
CSI/PVPR&D
Review at early stage the
sustainability of R&D projects
PORTFOLIO VALUE PROGRAM
Screening before
commercialization to ensure final
sustainability classification and
allow for EcoTain branding
SCOPESCOUT EXECUTE COMMERCIALIZE
SUBSTANCE EVALUATION
CompTox Suite/
Testing/Dossiers

7. Dr. Erika Kunz, Global Product Stewardship, Global Registration and Evaluation of Chemicals, 09.06.2017
Conclusion
– Clariant uses wherever possible novel approaches to
generate data and manage chemical hazards and risks for
- Regulatory purpose as well as for innovation, and
- This information is integrated into the sustainability
evaluation of our entire product portfolio.
– Clariant advocates and strives for broader acceptance of
alternative methods
– But: We see a fragmented picture on the acceptance of
alternative approaches by regulators
Public, Speeding up chemical assessments: from novel information to new management approaches, what works?7

8. Public
Dr. Erika Kunz
Global Product Stewardship
Global Registration and Evaluation of Chemicals
09.06.2017
Thank you for your attention