This document outlines indicators to measure progress toward targets set in the 2011 UN Political Declaration on HIV/AIDS. It lists 14 specific targets to be achieved by 2015 related to reducing transmission, increasing access to treatment, and strengthening synergies with development. Data on over 30 indicators will be collected biennially from countries and used to assess progress in annual UN reports on the global AIDS response. The indicators and guidelines aim to provide standardized measurement of commitments to respond to the AIDS epidemic.