This document provides a list of publications by Jan VAN LOO related to prebiotics and their effects. It includes 28 publications from 2001-2009 covering topics such as: - Effects of prebiotic supplementation on stool metabolites and gut microbiota in senior cats. - Prebiotics supporting the growth of probiotic bacteria in vitro. - Prebiotics modulating markers of tumor progression in human colon tumor cells. - Synbiotic consumption modulating cancer risk biomarkers in human subjects. - Prebiotic treatment decreasing colon carcinogenesis in rats. - Prebiotics having potential anticarcinogenic activities when evaluated in human volunteers.

1. Jan VAN LOO
PAPERS
REFERENCE
PUBLICATION
YEAR
Fructan supplementation of senior cats affects stool metabolite
concentrations and fecal microbiota concentrations, but not nitrogen
partitioning in excreta.
Barry KA, Hernot DC, Van Loo J, Fahey GC Jr, de Godoy MR.
J Anim Sci. 2014 Nov;92(11):4964-71. doi: 10.2527/jas.2013-7510. 2014
Van Loo J, “Natural selection” Position paper on Clean Lable. In International
Ingredient Magazine (Nov 2013). 2013
Rurangwa E; Laranja J L; Van HouR; DelaeY; Geraylou Z; Van de Wiele T;
Van loo J; Van Craeyveld V; Courtin C M; Delcour J A; Ollevier F (2009)
Selected nondigestible carbohydrates and prebiotisupport the growth of
probiotic fish bacteria mono-cultures in vitro.
Journal of applied microbiology, vol 106 (3); pp 932-940 2009
Inflammatory disease processes and interactions with nutrition
Calder, P. C.; Albers, R.; Antoine, J.-M.; Blum, S.; Bourdet-Sicard, R.;
Ferns, G. A.; Folkerts, G.; Friedmann, P. S.; Frost, G. S.; Guarner, F.;
Lovik, M.; MacFarlane, S.; Meyer, P. D.; M'Rabet, L.; Serafini, M.; van
Eden, W.; van loo, J.; Vas Dias, W.; Vidry, S.; Winklhofer-Roob, B. M.;
British Journal of Nutrition (2009), 101(Suppl. 1), S1/T,S1/TC,S1-S45 2009
Prebiotiand animal nutrition
Van loo, Jan; Vancraeynest, Dieter
ORAFTI, Tienen, Belg.
Handbook of Prebioti(2008), 421-436. Editor(s): Gibson, Glenn R.;
Roberfroid, Marcel B. Publisher: CRC Press, Boca Raton, Fla.
CODEN: 69KMMX; ISBN: 978-0-8493-8171-3
DOI 10.1201/9780849381829.ch21
Conference; General Review 2008
Bosscher, Douwina; Van loo, Jan (2008) Oligofructose -enriched inulin :
keeping optimal body weight
Nutrafoods vol 7; pp 21-25 2008
Inulin-type fructans
Van loo, Jan; Bosscher, Douwina
BENEO-Orafti, Tienen, B3300, Belg.
Therapeutic Microbiology (2008), 147-157. Editor(s): Versalovic, James;
Wilson, Michael. Publisher: American Society for Microbiology,
Washington,
D. C.
CODEN: 69LALZ; ISBN: 978-1-55581-403-8
Conference; General Review 2008
Oligofructose-enriched inulin: keeping optimal body weight Bosscher,
Douwina; Van loo, Jan BENEO-Orafti, Tienen, Belg. Nutrafoods (2008),
7(1), 21-25 2008

2. Dietary synbiotireduce cancer risk factors in polypectomized and colon
cancer patients
Rafter, Joseph; Bennett, Michael; Caderni, Giovanna; Clune, Yvonne;
Hughes, Roisin; Karlsson, Pernilla C.; Klinder, Annett; O'Riordan,
Micheal; O'Sullivan, Gerald C.; Pool-Zobel, Beatrice; Rechkemmer,
Gerhard;
Roller, Monika; Rowland, Ian; Salvadori, Maddalena; Thijs, Herbert; Van
Loo, Jan (Reprint); Watzl, Bernhard; Collins, John K.
AMERICAN JOURNAL OF CLINICAL NUTRITION, (FEB 2007) Vol. 85, No. 2,
pp.
488-496.
ISSN: 0002-9165. 2007
How chicory fructans contribute to zootechnical performance and well-being
in livestock and companion animals
Van loo, Jan
ORAFTI, Tienen, B3300, Belg.
Journal of Nutrition (2007), 137(11S), 2594S-2597S
CODEN: JONUAI; ISSN: 0022-3166 2007
Inulin and oligofructose as prebiotiin the prevention of intestinal
infections and diseases
Bosscher, D.; Van loo, J.; Franck, A.
ORAFGroup, Tienen, B-3300, Belg.
Nutrition Research Reviews (2006), 19(2), 216-226 2006
Inulin and oligofructose as functional ingredients to improve bone
mineralization
Bosscher, D.; Van loo, J.; Franck, A.
Tiense Suikerraffinaderij, Orafti, Tienen, 3300, Belg.
International Dairy Journal (2006), 16(9), 1092-1097 2006
Inulin and oligofructose in lowering the risk of osteoporosis: a major
concern for women's health
Bosscher, Douwina; Van loo, Jan; Franck, Anne
Orafti, Tienen, B3300, Belg.
Agro Food Industry Hi-Tech (2006), 17(1), 10-12 2006
Prebiotic Synergy1 (oligofructose enriched inulin) reduces risk factors
for osteoporosis
Van loo J (Reprint); Bosscher D; Franck A
ORAFTI, Nutr Res, B-3300 Tienen, Belgium
CYA Belgium
FASEB JOURNAL, (7 MAR 2006) Vol. 20, No. 5, Part 2, pp. A1064-A1064. 2006
Experimental modulation of cancer risk factors by prebiotic oligofructose
enriched inulin (Synergy1) is confirmed in human volunteers Van loo J
(Reprint); Bosscher D; Franck A ORAFTI, B-3300 Tienen, BelgiumCYA
Belgium FASEB JOURNAL, (7 MAR 2006) Vol. 20, No. 5, Part 2, pp. A994-
A994. 2006

3. On the use of prebiotic food ingredient Synergy1 (Oligofructose enriched
inulin) in the management of inflammatory bowel disease
Van loo J (Reprint); Bosscher D; Franck A; Guarner F
ORAFTI, B-3300 Tienen, Belgium; Hosp Gen Valle Hebron, Digest Syst Res
Unit, Barcelona 08035, Spain
CYA Belgium; Spain
FASEB JOURNAL, (7 MAR 2006) Vol. 20, No. 5, Part 2, pp. A989-A989. 2006
Human evolution, nutritional ecology and prebiotiin ancient diet
Leach, Jeff D.; Gibson, Glenn R.; Van loo, Jan
School of Archaeology & Ancient History, University of Leicester,
Leicester, LE1 7RH, UK
Bioscience and Microflora (2006), 25(1), 1-8 2006
Inulin and oligofructose: in the prevention of osteoporosis
Bosscher, Douwina; Van loo, Jan; Franck, Anne
Orafti, Tienen, B3300, Belg.
Nutrafoods (2005), 4(2/3), 69-73 2005
Prebiotic oligofructose-enriched chicory inulin combination with
probiotics: in the prevention of colon cancer in experimental models and
human volunteers
Van loo, Jan; Clune, Yvonne; Bosscher, Douwina; Franck, Anne
OrafGroup, Tienen, B3300, Belg.
Agro Food Industry Hi-Tech (2005), 16(4), 6-8 2005
The SYNCAN project: goals, set-up, first results and settings of the human
intervention study
Van loo J (Reprint); Clune Y; Bennett M; Collins J K
BRITISH JOURNAL OF NUTRITION, (APR 2005) Vol. 93, Supp. [1], pp. S91-
S98.
ISSN: 0007-1145. 2005
Consumption of chicory fructans and probiotireduces cancer risk
biomarkers in colon cancer and polypectomized human subjects.
Van loo J (Reprint); Bosscher D; Caderni G; Collins J K; Pool-Zobel B;
Rowland I; Watzl B; Rafter J
CYA Belgium; Italy; Ireland; Germany; North Ireland; Sweden
CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION, (NOV 2005) Vol.
14, No. 11,
Part 2, Supp. [S], pp. 2723S-2724S. 2005
Markers to measure immunomodulation in human nutrition intervention
studies Albers R; Antoine J M; Bourdet-Sicard R; Calder P C; Gleeson M;
Lesourd B; Samartin S (Reprint); Sanderson I R; Van loo J; Vas Dias F W;
Watzl BCYA Belgium; Netherlands; France; England; Germany BRITISH
JOURNAL OF NUTRITION, (SEP 2005) Vol. 94, No. 3, pp. 452-481. 2005

4. Gut fermentation products of inulin-derived prebiotibeneficially
modulate markers of tumour progression in human colon tumour cells
Klinder, Annett; Gietl, Eva; Hughes, Roisin; Jonkers, Nadine; Karlsson,
Pernilla; McGlyn, Hugh; Pistoli, Stella; Tuohy, Kieran; Rafter, Joseph;
Rowland, Ian R.; van loo, Jan; Pool-Zobel, Beatrice L.
Department of Nutritional Toxicology, Institute for Nutrition, Friedrich
Schiller University, Jena, D-07743, Germany
International Journal of Cancer Prevention (2004), 1(1), 19-32
CODEN: IJCPC6; ISSN: 1554-1134 2004
Synbiotic consumption modulates cancer risk biomarkers in colon cancer
and
polypectomised human subjects.
Clune Y (Reprint); Meaney K; O'Donoghue M; Klinder A; May M; Roller M;
Karlsson P; Hughes R; Jonkers N; Salvadori M; Bennett M; O'Riordan M;
Dunne C; O'Sullivan G; van loo J; Rechkemmer G; Rafter J; Watzl B;
Caderni G; Rowland I; Pool-Zobel B L; Collins J K
CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION, (NOV 2004) Vol.
13, No. 11,
Part 2, pp. 1828S-1829S. 2004
Synergy1: Orafti's second generation chicory fructan with significantly
enhanced nutritional properties
van loo, Jan
ORAFTI, Tienen, Belg.
Agro Food Industry Hi-Tech (2004), 15(6), 6-8 2004
Dietary modulation of the human colonic microbiota: updating the concept
of prebiotics
Gibson, Glenn R.; Probert, Hollie M.; van loo, Jan; Rastall, Robert A.;
Roberfroid, Marcel B.
Nutrition Research Reviews (2004), 17(2), 259-275 2004
The specificity of the interaction with intestinal bacterial fermentation
by prebiotidetermines their physiological efficacy
Van loo J (Reprint)
ORAFTI, Aandorenstr 1, B-3300 Tienen, Belgium (Reprint); ORAFTI, B-3300
Tienen, Belgium
Jan.Van.Loo@orafti.com
CYA Belgium
NUTRITION RESEARCH REVIEWS, (JUN 2004) Vol. 17, No. 1, pp. 89-98. 2004
PASSCLAIM-diet-related cancer
Rafter, Joseph; Govers, Mirjam; Martel, Paule; Pannemans, Daphne;
Pool-Zobel, Beatrice; Rechkemmer, Gerhard; Rowland, Ian; Tuijtelaars,
Sandra; van loo, Jan
European Journal of Nutrition (2004), 43(Suppl. 2), II/47-II/84 2004
Prebiotipromote good health: The basis, the potential, and the emerging
evidence
Van loo J A E (Reprint)
JOURNAL OF CLINICAL GASTROENTEROLOGY, (JUL 2004) Vol. 38, No. 6,
Supp.
[S], pp. S70-S75. 2004

5. Prebiotic treatment modulates the gut-associated immune system and
decreases AOM-induccd colon carcinogenesis in F344 rats.
Roller M (Reprint); Femia P; Caderni G; Rechkemmer G; Van Loo J; Watzl B
CYA Germany; Italy; Belgium
CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION, (NOV 2003) Vol.
12, No. 11,
Part 2, Supp. [S], pp. 1335S-1335S. 2003
Nutritional responses to the presence of inulin and oligofructose in the
diets of domesticated animals: a review
Flickinger, Elizabeth A.; Van loo, Jan; Fahey, George C., Jr.
Critical Reviews in Food Science and Nutrition (2003), 43(1), 19-60 2003
Prebiotic Synergy1 and Sulindac, a nonsteroidal anti-inflammatory drug:
Effect on azoxymethane-induced aberrant crypt foci in Fisher rats.
Verghese M (Reprint); Bonsi I A; Walker L T; Shackelford L; Chawan C B;
Van loo J
JOURNAL OF NUTRITION, (NOV 2003) Vol. 133, No. 11, Supp. [1], pp.
3854S-3854S. 2003
A population-based study of glutathione S-transferase M1, T1 and P1
genotypes and risk for lung cancer
Nazar-Stewart V (Reprint); Vaughan T L; Stapleton P; Van loo J;
Nicol-Blades B; Eaton D L
LUNG CANCER, (JUN 2003) Vol. 40, No. 3, pp. 247-258.
ISSN: 0169-5002. 2003
Molecular biological methods for studying the gut microbiota: The EU
human
gut flora project
Blaut, M.; Collins, M. D.; Welling, G. W.; Dore, J.; Van loo, J.; De
Vos, W.
British Journal of Nutrition (2002), 87(Suppl. 2), S203-S211 2002
Inhibitory effect of nonsteroidal anti-inflammatory drugs (NSAIDs) on
azoxymethane-induced aberrant crypt foci in rats is enhanced by Synergy
1.
Verghese M (Reprint); Walker L T; Richardson J E W; Bonsi I A;
Shackelford
L; Chawan C B; Van loo J
Alabama A&M Univ, Normal, AL 35762 USA; ORAFTI, Tienen, Belgium
CYA USA; Belgium
CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION, (OCT 2002) Vol. 11,
No. 10,
Part 2, pp. 1155S-1155S. MA A213. 2002
Experimental evidences on the potential of prebiotic fructans to reduce
the risk of colon cancer
Pool-Zobel, B.; Van loo, J.; Rowland, I.; Roberfroid, M. B.
British Journal of Nutrition (2002), 87(Suppl. 2), S273-S281 2002
Van loo, J and Jonkers, N (2001) Evaluation in human volunteer of the
potential anticarcinogenic activities of novel nutritional concepts : prebiotics,
probiotiand synbiotics. Nutr. Metab. Cardiovasc. Dis Suppl to No 4, pp. 87-
93 2001

6. Effects of dietary sucrose on hippocampal serotonin release: a
microdialysis study in the freely-moving rat
Smolders, Ilse; Van loo, Jan; Sarre, Sophie; Ebinger, Guy; Michotte,
Yvette
British Journal of Nutrition (2001), 86(2), 151-155 2001
Functional food properties of non-digestible oligosaccharides: a consensus
report from the ENDO project (DGXII AIRII-CT94-1095)
Van loo, Jan; Cummings, John; Delzenne, Nathalie; Englyst, Hans; Franck,
Anne; Hopkins, Mark; Kok, Nadine; MacFarlane, George; Newton,
Dorothy;
Quigley, Michael; Roberfroid, Marcel; Van Vliet, Trinette; Van Den
Heuvel,
Ellen
ORAFTI, Tienen, B3300, Belg.
British Journal of Nutrition (1999), 81(2), 121-132 1999
Roberfroid,M. B.; Van loo,J. & Gibson,G. R. (1998) The bifidogenic nature of
chicory inulin and its hydrolysis products Journal of Nutrition, vol. 128(1);
pp. 11-19. 1998
Van loo,J. (1998) Potential health benefits of non-digestible oligosaccharide
Lebensmittel-Technologie, vol. 31(5); pp. 162-168. 1998
On the presence of inulin and oligofructose as natural ingredients in the
Western diet
Van loo, Jan; Coussement, Paul; De Leenheer, Leen; Hoebregs, Hubert;
Smits, Georges
Critical Reviews in Food Science and Nutrition (1995), 35(6), 525-52 1995
Dietary fiber inulin and oligofructose as food ingredients
Van loo, J.
Tienen, B-3300, Belg.
Voeding (1995), 56(4), 6-9 1995
Non-digestible oligosaccharides and bifidobacteria - implications for
health
Gibson, Glenn R.; Willis, Caroline L.; Van loo, Jan
Med. Res. Council, Dunn Clinical Nate. Cen., Cambridge, UK
International Sugar Journal (1994), 96(1150), 381-7 1994
The identification by proton and carbon-13 NMR spectroscopy of sucrose,
1-kestose, and neoketose in mixtures present in plant extracts
De Bruyn, Andre; Van loo, Jan
Carbohydrate Research (1991), 211(1), 131-6 1991
Characteristiof pectins extracted from sugar-beet pulp by Geotrichum
penicillatum
Ralet, Marie Christine; Thibault, J. F.; Hallaert, J.; Vandamme, E.; Van
Loo, J.
Sciences des Aliments (1990), 10(4), 865-76 1990

7. Nutritional, physiological and process-technological improvements of the
xanthan fermentation process
De Vuyst, L.; Vermeire, A.; Van loo, J.; Vandamme, E. J.
Fac. Agric. Sci., State Univ. Ghent, Ghent, 9000, Belg.
Mededelingen van de Faculteit Landbouwwetenschappen, Universiteit Gent
(1987), 52(4B), 1881-900 1987
Microbial sucrose phosphorylase: fermentation process, properties, and
biotechnical applications
Vandamme, Erick J.; Van loo, Jan; Machtelinckx, Lieve; De Laporte, Andre
Advances in Applied Microbiology (1987), 32, 163-201 1987
Optimization of sucrose phosphorylase production by Leuconostoc
mesenteroides
Vandamme, Erick J.; Van loo, Jan; Simkens, Eric; De Laporte, Andre
Journal of Chemical Technology and Biotechnology (1987), 39(4), 251-62 1987
Two-step fermentation process for improved xanthan production by
Xanthomonas campestris NRRL-B-1459
De Vuyst, Luc; Van loo, Jan; Vandamme, Erick J.
Journal of Chemical Technology and Biotechnology (1987), 39(4), 263-73 1987
Dynamiand regulation of sucrose phosphorylase formation in Leuconostoc
mesenteroides fermentations
Vandamme, E. J.; Van loo, J.; De Laporte, A.
Biotechnology and Bioengineering (1987), 29(1), 8-15 1987
Leuconostoc mesenteroides sucrose phosphorylase: improved fermentation
process, immobilization, and applications
Vandamme, E. J.; Van loo, J.; Machtelinckx, L.; Simkens, E.; De Laporte,
A.
Eur. Congr. Biotechnol., 3rd (1984), Volume 1, 333-8 Publisher: Verlag 1984