This document provides a summary of Jack Ryan Reifert's education, experience, publications, and research skills. Reifert holds a Ph.D. in Molecular, Cellular, and Developmental Biology from UCSB and a B.S. in Pharmacological Chemistry from UCSD. He has postdoctoral research experience at UCSB studying bacterial peptide display for ovarian cancer detection and inhibition. Reifert has over 10 years of experience in neuroscience research and industrial research, and he has authored several publications in peer-reviewed journals.
Biology Molecular
University of Haifa. (2015, August 13). Big data and the social character of genes. ScienceDaily. Retrieved September 12, 2015 from www.sciencedaily.com/releases/2015/08/150813084035.htm
Lawrence Berkeley National Laboratory. (2015, August 4). Keeping algae from stressing out. ScienceDaily. Retrieved September 12, 2015 from www.sciencedaily.com/releases/2015/08/150804144013.htm
Martínez Sánchez, Lina María. Biología Molecular. 8.ed. Medellín. UPB. Facultad de Medicina.
Biology Molecular
University of Haifa. (2015, August 13). Big data and the social character of genes. ScienceDaily. Retrieved September 12, 2015 from www.sciencedaily.com/releases/2015/08/150813084035.htm
Lawrence Berkeley National Laboratory. (2015, August 4). Keeping algae from stressing out. ScienceDaily. Retrieved September 12, 2015 from www.sciencedaily.com/releases/2015/08/150804144013.htm
Martínez Sánchez, Lina María. Biología Molecular. 8.ed. Medellín. UPB. Facultad de Medicina.
Molecular Biologist Academic CV for Industry or Private Sector Consideration Sirie Godshalk
Molecular Biologist with over thirteen years of hands-on research experience, impactful writer and presenter, dynamic leader and enthusiastic team player with an eye for great ideas and a passion to move science in new directions seeks challenging opportunities beyond the bench.
Journal of Ethnobotany | Applications of DNA barcoding and future directions ...Innspub Net
DNA barcoding help to recognize the plant based on short, gene sequences in a rapid, accurate, and cost effective manner. Current focus is on the investigation of phytomedicinals and herbal product integrity and authenticity through DNA barcoding with the goal of protecting consumers from potential health risks associated with product substitution and contamination. Recent reports reveal that DNA barcoding can be used for the assignment of unknown specimens to a taxonomic group, authentic identification of phytomedicinals, and in plant biodiversity conservation. Research indicates that there is no single universal barcode candidate for identification of all plant groups. Hence, comparative analysis of plant barcode loci is essential for choosing a best candidate for authenticating particular medicinal plant genus/families. Currently, both chloroplast/nuclear regions are used as universal barcodes for the authentication of phytomedicinals. A recent advance in genomics has further enhanced the progress in DNA barcoding of plants by the introduction of high-throughput techniques like next generation sequencing, which has paved the way for complete plastome sequencing that is now termed as super-barcodes. Hence, current focus is on the investigation of phytomedicines and herbal product integrity and authenticity through DNA barcoding with the goal of protecting consumers from potential health risks associated with product substitution and contamination. These approaches could improve the traditional ethnobotanical and scientific knowledge of phytomedicines and their safe use.
International Conference on Genetic Engineering & Genetically Modified Organisms, will be organized around the theme "The Power of Gene in turning Ordinary into Extraordinary."
24° CORSO RESIDENZIALE DI AGGIORNAMENTO
con il patrocinio dell’Associazione Italiana di Radioterapia Oncologica (AIRO)
Moderna Radioterapia, Nuove Tecnologie e Ipofrazionamento della Dose
La rivoluzione dell’introduzione del modello LQ nella pratica clinica
this presentation depicts the usefulness of single cell profiling in crop plant for identifying novel gene sources which can be used for crop improvement
American Society for Microbiology NGS 2020 Aine O'TooleÁine Niamh O'Toole
200,001: A tree-space odyssey. Pandemic phylogenetics and reporting in 2020. Aine O'Toole Plenary
Pipe Dreams: Analytical Methods, Bioinformatic Tools and Pipelines
Molecular Biologist Academic CV for Industry or Private Sector Consideration Sirie Godshalk
Molecular Biologist with over thirteen years of hands-on research experience, impactful writer and presenter, dynamic leader and enthusiastic team player with an eye for great ideas and a passion to move science in new directions seeks challenging opportunities beyond the bench.
Journal of Ethnobotany | Applications of DNA barcoding and future directions ...Innspub Net
DNA barcoding help to recognize the plant based on short, gene sequences in a rapid, accurate, and cost effective manner. Current focus is on the investigation of phytomedicinals and herbal product integrity and authenticity through DNA barcoding with the goal of protecting consumers from potential health risks associated with product substitution and contamination. Recent reports reveal that DNA barcoding can be used for the assignment of unknown specimens to a taxonomic group, authentic identification of phytomedicinals, and in plant biodiversity conservation. Research indicates that there is no single universal barcode candidate for identification of all plant groups. Hence, comparative analysis of plant barcode loci is essential for choosing a best candidate for authenticating particular medicinal plant genus/families. Currently, both chloroplast/nuclear regions are used as universal barcodes for the authentication of phytomedicinals. A recent advance in genomics has further enhanced the progress in DNA barcoding of plants by the introduction of high-throughput techniques like next generation sequencing, which has paved the way for complete plastome sequencing that is now termed as super-barcodes. Hence, current focus is on the investigation of phytomedicines and herbal product integrity and authenticity through DNA barcoding with the goal of protecting consumers from potential health risks associated with product substitution and contamination. These approaches could improve the traditional ethnobotanical and scientific knowledge of phytomedicines and their safe use.
International Conference on Genetic Engineering & Genetically Modified Organisms, will be organized around the theme "The Power of Gene in turning Ordinary into Extraordinary."
24° CORSO RESIDENZIALE DI AGGIORNAMENTO
con il patrocinio dell’Associazione Italiana di Radioterapia Oncologica (AIRO)
Moderna Radioterapia, Nuove Tecnologie e Ipofrazionamento della Dose
La rivoluzione dell’introduzione del modello LQ nella pratica clinica
this presentation depicts the usefulness of single cell profiling in crop plant for identifying novel gene sources which can be used for crop improvement
American Society for Microbiology NGS 2020 Aine O'TooleÁine Niamh O'Toole
200,001: A tree-space odyssey. Pandemic phylogenetics and reporting in 2020. Aine O'Toole Plenary
Pipe Dreams: Analytical Methods, Bioinformatic Tools and Pipelines
The Impact of Artificial Intelligence on Modern Society.pdfssuser3e63fc
Just a game Assignment 3
1. What has made Louis Vuitton's business model successful in the Japanese luxury market?
2. What are the opportunities and challenges for Louis Vuitton in Japan?
3. What are the specifics of the Japanese fashion luxury market?
4. How did Louis Vuitton enter into the Japanese market originally? What were the other entry strategies it adopted later to strengthen its presence?
5. Will Louis Vuitton have any new challenges arise due to the global financial crisis? How does it overcome the new challenges?Assignment 3
1. What has made Louis Vuitton's business model successful in the Japanese luxury market?
2. What are the opportunities and challenges for Louis Vuitton in Japan?
3. What are the specifics of the Japanese fashion luxury market?
4. How did Louis Vuitton enter into the Japanese market originally? What were the other entry strategies it adopted later to strengthen its presence?
5. Will Louis Vuitton have any new challenges arise due to the global financial crisis? How does it overcome the new challenges?Assignment 3
1. What has made Louis Vuitton's business model successful in the Japanese luxury market?
2. What are the opportunities and challenges for Louis Vuitton in Japan?
3. What are the specifics of the Japanese fashion luxury market?
4. How did Louis Vuitton enter into the Japanese market originally? What were the other entry strategies it adopted later to strengthen its presence?
5. Will Louis Vuitton have any new challenges arise due to the global financial crisis? How does it overcome the new challenges?
1. Jack Ryan Reifert
Home Address: 2528 Orella St. Unit-B • Santa Barbara, CA 93109 • 858-922-5923 • reifert@lifesci.ucsb.edu
Work Address: Neuroscience Research Institute • BLDG. 571, RM. 6131 • Santa Barbara, CA 93106-5060
Education:
Ph.D. Molecular, Cellular, and Developmental Biology (MCDB) / Neuroscience Research Institute 2005-2011
University of California, Santa Barbara (UCSB)
B.S. Pharmacological Chemistry 1996-2000
University of California, San Diego (UCSD)
Additional Education:
• Technology Management Program at UCSB: Business education courses pertaining to the health care industry. 2009-2011
• UCSD Extension courses: Introduction to Pharmacology, Mechanisms of Disorders I and II, Neuropharmacology 2002-2005
Industrial Research Experience:
Salmedix INC. La Jolla, CA / Research Associate 2002-2005
Bendamustine (Treanda), won FDA approval for treatment of Chronic Lymphocytic Leukemia (CLL)
and Non-Hodgkin’s Lymphoma (NHL), 3 years after being acquired by Cephalon pharmaceuticals.
• Working with the biology research group, our work directly influenced Bendamustine clinical trails for B-cell NHL
and provided evidence for a mechanism of action divergent from other chemotherapies. (See publication for reference.)
BD Pharmingen. La Jolla, CA / Quality Control Associate I 2001-2002
• Coordinated team meetings to efficiently approach “problem” products, resulting in release of multiple reagents
from backorder and updated data sheets with new information specific to each product.
Academic Research Experience:
Chemical Engineering (UCSB), Santa Barbara, CA / Postdoctoral Fellow (CIRM) 2011-Present
• Topic: Using bacterial peptide display for the detection and inhibition of proteases involved in ovarian cancer
metastasis with an emphasis on targeting cancer stem cells.
Neuroscience Research Institute (UCSB), Santa Barbara, CA / Graduate Research Assistant 2005-2011
• Topic: Mechanisms of amyloid beta induced neurodegeneration - involvement of microtubule associated protein tau.
Sam and Rose Stein Institute for Research on Aging (UCSD), La Jolla, CA / Research Associate 1999-2001
• Was an author on two publications for investigating the involvement of wnt / β-catenin signaling in the promotion
of rheumatoid arthritis using primary synoviocytes isolated from patients.
Selected Publications:
Reifert J, Hartung-Cranston D, Feinstein S.C. “Tau fragmentation without marked changes in tau phosphorylation precedes
amyloid beta mediated cell death in cultured hippocampal neurons.” J Biol Chem. 286(23): 20797-811. Jun. 2011
Leoni LM, Bailey B, Reifert J, Bendall HH, Zeller RW, Corbeil J, Elliott G, Niemeyer CC. “Bendamustine (Treanda) displays a
distinct pattern of cytotoxicity and unique mechanistic features compared with other alkylating agents.” Clin Cancer Res. 14(1): 309
17. Jan. 2008
Sen M, Reifert J, Lauterbach K, Wolf V, Rubin JS, Corr M, Carson DA. “Regulation of fibronectin and metalloproteinase expression
by Wnt signaling in rheumatoid arthritis synoviocytes.” Arthritis Rheum. 46(11): 2867-77. Nov. 2002
Selected Research Skills:
Dissection and culture of primary neurons RNA, DNA, protein isolation Site-directed mutagenesis
Glial cell isolation Molecular cloning/subcloning Flow cytometry
Tissue embedding and sectioning PCR, qPCR, primer design Live and fixed-cell imaging
Mammalian tissue culture HPLC Protein purification Peptide display library design
Immunoprecipitation Transformation / Transfection Size exclusion chromatography
In-vivo drug delivery (oral gavage, IV) Western blotting / 2D Westerns Virus production / infection
Multiple microscopy systems including fluorescent, confocal, and DSU. Cytotoxicity assays