1. Jack R. Reifert
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2528 Orella St. Unit B
Santa Barbara, CA 93105
Phone: (858) 922-5923 Email: jackreifert@gmail.com
EDUCATION
2005-2011 Doctor of Philosophy (Ph.D.) - Molecular, Cellular, and Developmental Biology (MCDB)
University of California, Santa Barbara
1996-2000 Bachelor of Science (B.S.) - Pharmacological Chemistry
University of California, San Diego
INDUSTRY RESEARCH EXPERIENCE
2014-Present Serimmune INC., Santa Barbara, CA Scientist
• Utilize peptide display screening, deep sequencing, and antigen discovery for patient antibody profiling
• Lead scientist on project to identify therapeutic candidates to block autoantibodies in Graves Disease
• Discovered motif panels specific to two autoimmune diseases for biomarker development
• Developed improved screening and deep sequencing techniques to map patient specific antibody
recognition repertoires
2002-2005 Salmedix INC., La Jolla, CA Research Associate
• Investigated mechanism of action, evaluated combination potential, and tested second-generation
analogs on small-molecule cancer therapeutics
• Bendamustine (Treanda) research supported clinical trials for B-Cell NHL (FDA approval in 2008)
• Published results indicating Treanda’s mechanism of action is divergent from other chemotherapies
• Designed a functional assay to support IHC scoring when typing patients for inclusion in clinical trials
2001-2002 BD Pharmingen, La Jolla, CA Quality Control Associate I
• Tested antibodies in immunoblotting, ELISA, and flow-cytometry assays for product release
ACADEMIC RESEARCH EXPERIENCE
2011-2014 Chemical Engineering (UCSB), Santa Barbara, CA Postdoctoral Fellow (CIRM)
Advisor: Professor Patrick Daugherty, Ph.D.
Projects: Discovery and engineering stable peptide inhibitors targeting proteases involved in metastasis.
Screening bacterial display libraries to identify antigen motifs specific to autoimmune disease.
• Awarded a CIRM fellowship to use protease inhibitor peptides to target and image cancer stem cells
• Published results implementing a proof-of-principal study using deep sequencing technology on
peptide libraries screened for serum antibody binding in celiac disease
2005-2011 Neuroscience Research Institute (UCSB), Santa Barbara, CA Graduate Researcher
Advisor: Professor Stuart Feinstein, Ph.D.
Thesis Topic: Involvement of tau in the mechanism of amyloid beta induced neurodegeneration.
2000-2001 Stein Institute for Research on Aging (UCSD), La Jolla, CA Research Associate
Advisors: Dr. Dennis Carson, M.D. and Dr. Malini Sen, Ph.D.
Research: Wnt / β-catenin signaling pathway involvement in the progression of rheumatoid arthritis.

2. Jack R. Reifert
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SELECTED PUBLICATIONS
Pantazes RJ, Reifert J, Isben KN, Guzman E, Zhou HJ, Kosik KS, Daugherty PS. “Identification of disease-specific motifs
in the antibody specificity repertoire via next-generation sequencing.” Submitted Feb. 2016 to Scientific Reports
Benbow SJ, Cook BM, Reifert J, Wozniak KM, Slusher BS, Littlefield BA, Wilson L, Jordan MA, Feinstein SC. “Effects of
Paclitaxel and Eribulin in mouse sciatic nerve: a microtubule-based rationale for the differential induction of chemotherapy-
induced peripheral neuropathy.” Neurotox Res. 29(2): 299-313. Feb. 2016
Shropshire TD, Reifert J, Rajagopalan S, Baker D, Feinstein SC, Daugherty PS. “Amyloid β peptide cleavage by kallikrein
7 attenuates fibril growth and rescues neurons from Aβ-mediated toxicity in vitro.” Biol Chem. 395(1): 109-18. Jan. 2014
Reifert J, Hartung-Cranston D, Feinstein S.C. “Amyloid β-mediated cell death of cultured hippocampal neurons reveals
extensive tau fragmentation without increased full-length tau phosphorylation.” J Biol Chem. 286(23): 20797-811. Jun. 2011
Sun CJ, Srivastava A, Reifert JR, Waite JH. “Halogenated DOPA in a marine adhesive protein.” J. Adhesion 85(2-3): 126-
138. Feb. 2009
Leoni LM, Bailey B, Reifert J, Bendall HH, Zeller RW, Corbeil J, Elliott G, Neimeyer CC. “Bendamustine (Treanda)
displays distinct pattern of cytotoxicity and unique mechanistic features compared with other alkylating agents.” Clin Cancer
Res. 14(1): 309-17. Jan. 2008
HONORS / AWARDS / SKILL DEVELOPMENT
2012-2014 California Institute for Regenerative Medicine (CIRM) Postdoctoral Fellowship
2010 Nominated and appointed Associate Faculty Member of Faculty of 1000 (F1000)
2008 Shing and Shang-Yung Chang Award for best 4
th
year graduate research talk
2005 Storke Award for highest achievement in first year graduate coursework
CONFERENCES AND MEETINGS
2010 Attended the 40
th
Society for Neuroscience Annual Meeting, San Diego
2009 Poster Presenter, 49
th
Meeting for The American Association for Cell Biology (ASCB), San Diego
2008 Poster Presenter, 47
th
Meeting for The American Association for Cell Biology (ASCB), San Francisco
2007 Attended the 37
th
Society for Neuroscience Annual Meeting, San Diego
2005 Poster Presenter, 7 Abstracts at the 96
th
American Association for Cancer Research (AACR), Anaheim
2004 Poster Presenter, 46
th
American Association of Hematology (ASH), San Diego
2004 Poster Presenter, 5 Abstracts at the 95
th
American Association for Cancer Research (AACR), Orlando
2003 Poster Presenter, 3 Abstracts at the 94
th
American Association for Cancer Research (AACR), DC
SELECTED RESEARCH SKILLS
Culture of primary and transformed cells FACS analysis and sorting (Aria, FACSCalibur)
3D culture of primary cells Tissue embedding and sectioning (cryo, agarose)
In-vivo drug delivery and toxicity analysis Peptide display library design / construction / screening
In-vitro enzyme inhibition and activity assays Protein purification and characterization (HPLC)
Cell based assays: transfection, growth, toxicity, colony forming, invasion, migration
Deep sequencing amplicon library preparation – Ion Proton, HiSeq, NextSeq
DNA manipulation: cloning, site-directed mutagenesis, primer design, plasmid construction
Protein detection: ELISA, Western blot, Immunofluorescence microscopy (IFM), Immunohistochemistry (IHC)
Trained on multiple microscopy systems including fluorescent, confocal, and DSU
Computer skills: Microscopy analysis software (Slidebook, Metamorph, Image J, Fluoview), graphing programs (Prism,
Excel), MS Office, SAP, Filemaker, FlowJo, Calcusyn.
REFERENCES AVAILABLE UPON REQUEST