Profiling Hospital-Acquired Pathogens and Antibiotic Resistance Genes WebinarQIAGEN
Hospital-acquired infections (HAIs) are caused by bacterial, viral and fungal pathogens that easily spread through the body. The most common HAIs include urinary tract infections, bloodstream infections and pneumonia. HAIs are becoming more virulent and more resistant to the antibiotics typically used to fight them, making antibiotic resistance a serious public health concern. In this webinar, we will provide an overview of hospital-acquired pathogens and antibiotic resistance. We will also present tools to help you identify and characterize hospital-acquired bacterial species and antibiotic resistance genes in your research samples.
CHI's Bioassays for Immuno-Oncology Symposium, Oct. 23, 2017 in Washington, DCJames Prudhomme
Biological assays demonstrating drug characteristics such as potency, mechanism-of-action, and stability, are one of the most critical components of an FDA biologic submission. However, with more complex mechanisms-of-action, immunotherapies add a layer of difficulty to bioassay selection and development. At Cambridge Healthtech Institute's Inaugural Bioassays for Immuno-Oncology symposium, experts in bioassays for immuno-oncology therapies will discuss selection, development, and standards for bioassays and immunoassays. Special attention will be given to understanding the mechanism-of-action for immunotherapies, whether they be antibody- or cell-based. Overall, this one-day immersive symposium will outline a product life cycle approach for developing and implementing biological assays from preclinical studies to clinical development. This symposium is part of the Immunogenicity & Bioassay Summit.
How bioinformatic and sequencing data might inform the regulatory process - O...OECD Environment
24 June 2019: This OECD seminar presented and discussed the potential use of genome sequence, bioinformatic tools and databases in a regulatory decision process for microbial pesticides.
Profiling Hospital-Acquired Pathogens and Antibiotic Resistance Genes WebinarQIAGEN
Hospital-acquired infections (HAIs) are caused by bacterial, viral and fungal pathogens that easily spread through the body. The most common HAIs include urinary tract infections, bloodstream infections and pneumonia. HAIs are becoming more virulent and more resistant to the antibiotics typically used to fight them, making antibiotic resistance a serious public health concern. In this webinar, we will provide an overview of hospital-acquired pathogens and antibiotic resistance. We will also present tools to help you identify and characterize hospital-acquired bacterial species and antibiotic resistance genes in your research samples.
CHI's Bioassays for Immuno-Oncology Symposium, Oct. 23, 2017 in Washington, DCJames Prudhomme
Biological assays demonstrating drug characteristics such as potency, mechanism-of-action, and stability, are one of the most critical components of an FDA biologic submission. However, with more complex mechanisms-of-action, immunotherapies add a layer of difficulty to bioassay selection and development. At Cambridge Healthtech Institute's Inaugural Bioassays for Immuno-Oncology symposium, experts in bioassays for immuno-oncology therapies will discuss selection, development, and standards for bioassays and immunoassays. Special attention will be given to understanding the mechanism-of-action for immunotherapies, whether they be antibody- or cell-based. Overall, this one-day immersive symposium will outline a product life cycle approach for developing and implementing biological assays from preclinical studies to clinical development. This symposium is part of the Immunogenicity & Bioassay Summit.
How bioinformatic and sequencing data might inform the regulatory process - O...OECD Environment
24 June 2019: This OECD seminar presented and discussed the potential use of genome sequence, bioinformatic tools and databases in a regulatory decision process for microbial pesticides.
Real-Time Genome Sequencing of Resistant Bacteria Provides Precision Infectio...ExternalEvents
http://www.fao.org/about/meetings/wgs-on-food-safety-management/en/
Real-Time Genome Sequencing of Resistant Bacteria Provides Precision Infection Control in an Institutional Setting. Presentation from the Technical Meeting on the impact of Whole Genome Sequencing (WGS) on food safety management and GMI-9, 23-25 May 2016, Rome, Italy.
High-throughput sequencing data of microorganisms opens new perspectives for ...OECD Environment
24 June 2019: This OECD seminar presented and discussed the potential use of genome sequence, bioinformatic tools and databases in a regulatory decision process for microbial pesticides.
Regenerative Medicine: Impact of Convergence on Drug, Device, and Biologics D...MaRS Discovery District
Speaker Dr. Annemarie Moseley, CEO of Aggregate Therapeutics (Palo Alto) explores how drug-device combination products are altering the medical practice from development to regulation to treatment.
Part of the MaRS Emerging Technologies Event Series. More information on the series can be found here:
http://www.marsdd.com/emergingtech/
Looking for insights into current global regulatory expectations for viral safety? Read the special report from BioProcess International, in collaboration with Martin Wisher, Senior Regulatory Consultant focusing on BioReliance biosafety® services.
Web applications for rapid microbial taxonomy identification ExternalEvents
http://www.fao.org/about/meetings/wgs-on-food-safety-management/en/
Web applications for rapid microbial taxonomy identification. Presentation from the Technical Meeting on the impact of Whole Genome Sequencing (WGS) on food safety management -23-25 May 2016, Rome, Italy.
This 3-day event is the meeting place for international and domestic scientists to share case studies and project updates, showcase new techniques and form collaborations that pave the way towards the future of China’s biopharmaceutical industry.
EWMA 2013 - Ep451 An in vitro and clinical assessment of a nonadherent, antim...EWMAConference
Sharon Lindsay, Alexander Waite, Rachael McInnes, Breda Cullen, Systagenix, Gargrave, UK
Robert J. Snyder, DPM, MSc, CWS, Professor, Barry University SPM, Miami Shores, Florida, USA
Bioinformatics: Building the cornerstones of Sequence Homology and its use fo...OECD Environment
24 June 2019: This OECD seminar presented and discussed the potential use of genome sequence, bioinformatic tools and databases in a regulatory decision process for microbial pesticides.
Real-Time Genome Sequencing of Resistant Bacteria Provides Precision Infectio...ExternalEvents
http://www.fao.org/about/meetings/wgs-on-food-safety-management/en/
Real-Time Genome Sequencing of Resistant Bacteria Provides Precision Infection Control in an Institutional Setting. Presentation from the Technical Meeting on the impact of Whole Genome Sequencing (WGS) on food safety management and GMI-9, 23-25 May 2016, Rome, Italy.
High-throughput sequencing data of microorganisms opens new perspectives for ...OECD Environment
24 June 2019: This OECD seminar presented and discussed the potential use of genome sequence, bioinformatic tools and databases in a regulatory decision process for microbial pesticides.
Regenerative Medicine: Impact of Convergence on Drug, Device, and Biologics D...MaRS Discovery District
Speaker Dr. Annemarie Moseley, CEO of Aggregate Therapeutics (Palo Alto) explores how drug-device combination products are altering the medical practice from development to regulation to treatment.
Part of the MaRS Emerging Technologies Event Series. More information on the series can be found here:
http://www.marsdd.com/emergingtech/
Looking for insights into current global regulatory expectations for viral safety? Read the special report from BioProcess International, in collaboration with Martin Wisher, Senior Regulatory Consultant focusing on BioReliance biosafety® services.
Web applications for rapid microbial taxonomy identification ExternalEvents
http://www.fao.org/about/meetings/wgs-on-food-safety-management/en/
Web applications for rapid microbial taxonomy identification. Presentation from the Technical Meeting on the impact of Whole Genome Sequencing (WGS) on food safety management -23-25 May 2016, Rome, Italy.
This 3-day event is the meeting place for international and domestic scientists to share case studies and project updates, showcase new techniques and form collaborations that pave the way towards the future of China’s biopharmaceutical industry.
EWMA 2013 - Ep451 An in vitro and clinical assessment of a nonadherent, antim...EWMAConference
Sharon Lindsay, Alexander Waite, Rachael McInnes, Breda Cullen, Systagenix, Gargrave, UK
Robert J. Snyder, DPM, MSc, CWS, Professor, Barry University SPM, Miami Shores, Florida, USA
Bioinformatics: Building the cornerstones of Sequence Homology and its use fo...OECD Environment
24 June 2019: This OECD seminar presented and discussed the potential use of genome sequence, bioinformatic tools and databases in a regulatory decision process for microbial pesticides.
Current CV .
My objective is to obtain a rewarding and challenging research scientist position where my background and experience will contribute to the success of a growing company or research center.
Currently, I am a Senior Associate Scientist at Amgen Inc. and certified Molecular Biologist with the American Society of Clinical Pathology MB (ASCP). I have more than 10 years of experience in the biotechnology/ pharmaceutical industry. I am highly proficient in various lab techniques, technologies, and automation. I demonstrated consistent success in the execution of assay development and method validation activities supporting clinical stage programs within GCP and GLP regulated environments. I possess extensive experience in optimization and validation of drug potency assays (ELISA and cell based assays), protein purification and characterization, and DNA/RNA extraction and quantitation. I am a subject matter expertise in the areas of human and rodent cell lines propagation and tissue dis-aggregation. I have proven operational capabilities in the establishment of standard operating procedures to ensure our laboratory meets regulatory and business requirements.
I am a self-motivated professional who works effectively as an individual contributor or within a team matrix. As a quick learner, I can efficiently deliver results, easily adapt to changing environment and provide fresh ideas. My strengths include statistical analysis/guidance, report writing, and communication.
Thank you in advance for your consideration. Please feel free to call me at (805-990-6258), or by e-mail at (mahawally46@gmail.com) if you have questions or would like a list of references.
Sincerely,
Maha Rizk
1. JENNIFER ANNE GIBBONS, Ph.D.
2320 EDWARDS LANE. BEL AIR, MD 21015
(443) 401-9806 (cell)
jen.a.gibbons@gmail.com
Relevant Experience:
Research Biologist 2015- present
US Army Edgewood Chemical Biological Center
5183 Blackhawk Rd. E3150 APG-EA, MD 21010
Provided scientific support to the BioDefense Branch of the Edgewood Chemical Biological
Center’s (ECBC) BioSciences Division. Executed research focused on the identification of
physiological, toxicological and biochemical changes that occur as a result of exposure to
chemical threat agents and performed testing and evaluation of hand-held assays for the
detection of emerging chemical threats.
Senior Scientist II 2015 - 2015
Excet, Inc.
8001 Braddock Road Suite 303 Springfield, VA 22151
Provided scientific support to the BioDefense Branch of the Edgewood Chemical Biological
Center’s BioSciences Division for the evaluation of recombinant bacterial strains optimized for
the degradation of chemical nerve agents. Performed research to identify exposure to chemical
threat agents using biomarker detection via through pathway analysis of mRNA, miRNA and
phophoproteomics. Developed potential medical countermeasure to toxic effects of chemical
threat agents identified through pathways analysis. Provided subject matter input in the areas
of inhalation equipment of in vivo non-traditional agent (NTA) exposure, quantitative polymerase
chain reaction (PCR) expertise to scientist within the division by guiding best practices, assay
development and troubleshooting.
Senior Research Scientist 2014-2015
Science and Technology Corporation (STC)
111 C Bata Blvd. Belcamp, MD 21017
Supervisory role for STC staff within the BioSciences and Physical Sciences Division at the
Edgewood Chemical Biological Center (ECBC). Was instrumental in the development of
pathogen identification primer assay for use with the Luminex MAGPIX, a clinical diagnostics
instrument that enable the simultaneous, multiplexed platform used in the measurement of
proteins. Developed and delivered two detection assays for the identification of tick pathogens
that are currently under alpha testing at the United States Army Public Health Command
(USAPHC). Supported the Systems Biology approach at ECBC for the development of
biomarker detection through the application of pathway analysis of mRNA, miRNA, and
phosphoproteiomic data. Presented scientific results at the 2015 Biodefense and Emerging
Disease conference’s poster session in Washington, DC).
R&D Scientist 2010-2014
SABiosciences, a QIAGEN company
6951 Executive Way Frederick, MD 21703
Was directly involved with developing new content for all 96-well and 384-well PCR array
technologies using next-generation sequencing, mRNA expression, histone modifications, DNA
methylation, and miRNA, using bioinformatics, literature review, and customer feedback.
Assays were directed at the evaluation of areas such as host-pathogen interactions,
hepatotoxicity, neurotoxicity, and inflammation. Selected as the Product Champion for the
company’s RT2 Profiler PCR Arrays and was directly responsible for determining the number of
array necessary to meet annual revenue targets, planning new PCR array topics, and evaluating
key customer segments and market positioning. Assumed a program manager role in
determining milestones, revising standard operating procedures (SOPs) based on quality control
(QC) results, and successfully meeting project deadlines and budgets. Worked directly with
Marketing, Sales, Research and Development, and production departments regularly to support
company products.
Key Skills & Accomplishments:
Pragmatic Marketing, Inc. Certified:
Practical Product Management
Scientist experienced in area of
pharmacokinetic/pharmacodynamic
(PK/PD) methodologies
Provided R&D for the development of
medical countermeasure to toxic
effects of chemical threat agents
Examined the interrelation of breast
cancer, metabolic syndrome and
thrombosis via the plasminogen
activator system
Provided supervision of contractor staff
within BioSciences and Physical
Sciences Divisions of ECBC
Developed assays for the detection of
tick-borne pathogens that are currently
under alpha-testing at the United
States Army Public Health Command
(USAPHC
Chemical personnel reliability program
(cPRP) member
Experienced with working with
marketing, sales, R&D, and production
departments for product support and
webinar presentations
Experience in evaluating key customer
segments and market positioning
Briefed and trained sales staff
worldwide on products, sales and
standard operating procedures (SOPs)
Proposal and technical report writing
skills
Education
Ph.D. in Pharmacology 2006
Duke University, Durham, NC
B.S. in Chemistry 2001
Olivet Nazarene University
B.A. in Biology Magna cum laude 2001
Olivet Nazarene University
Certificate in Integrated Toxicology
SECURITY CLEARANCE: Secret
2. JENNIFER ANNE GIBBONS, Ph.D.
2320 EDWARDS LANE. BEL AIR, MD 21015
(443) 401-9806 (cell)
jen.a.gibbons@gmail.com
R&D Staff Scientist 2008 – 2010
SABiosciences Corp.
6951 Executive Way Frederick, MD 21703
Lead R&D scientist in QC troubleshooting of the company’s RT2 Nano preamp cDNA synthesis kit for the SABiosciences Production
Department. Adapted protocols for super-competent Escherichia coli production and developed in-house procedures resulting in substantial
cost-savings. Evaluated costs and benefits of several candidate outside sources for DNA sequencing services, and developed & optimized
methods for medium-throughput molecular cloning. Acquired expertise on the execution of multiple analytical platforms for detection of
miRNA and RNA transcripts using real-time PCR. Completed development of miRNA RT-PCR detection and quantitation assays, and created
original literature reviews and marketing materials for Marketing Department. Interacted with teams across multiple departments to transition
products from development to market and assisted in the creation of new product lines for the company.
Postdoctoral Fellow 2006 - 2008
University of North Carolina – Chapel Hill
302 Mary Ellen Jones Bldg. 98 Manning Dr. Chapel Hill, NC 27599
Completed a NIH-sponsored short course in Integrated and Organ Systems Biology (UNC-Chapel Hill Pharmacy School) that focused on
pharmacokinetic/pharmacodynamic (PK/PD) methodologies, and provided hands-on experience with relevant animal model systems.
Assisted in optimizing several enzymatic assay protocols addressing plasminogen activation and coagulation in order to improve both
quantitation and detection. Examined the interrelationship of breast cancer, metabolic syndrome and thrombosis by way of the plasminogen
activator system. Performed cell adhesion and motility assays; analyzed protein levels in conditioned media and cell lysates via quantitative
Western blot via the Odyssey® CLx Imaging System and analyzed microparticle formation by enzymatic assays, transmission electron
microscopy, flow cytometry and total phosphate content. Was responsible for the supervision of three undergraduate students and their
research projects. Received NIEHS Institutional Training Fellowship in Environmental Pathology.
EDUCATION
Ph.D. in Pharmacology, Certificate in Integrated Toxicology 2006
Duke University, Durham, NC
Dissertation: Regulation of Protein Phosphatase-1; Ph.D. Advisor: Dr. Shirish Shenolikar
Related Coursework: Macromolecular Synthesis, Essentials in Pharmacology/Toxicology, Cellular Signaling, Medical Pharmacology,
Interdisciplinary Approach to Pharmacology, Mammalian Toxicology, Focused Topics in Toxicology, Statistics for Basic Biomedical
Scientists, Structure of Biological Macromolecules, Biotechnology: Management of Drug Discovery
B.S. in Chemistry; B.A. in Biology Magna cum laude 2001
Olivet Nazarene University, Kankakee, IL
Related Coursework: General Biology, General Chemistry, General Physics, Microbiology, Toxicology, Genetics, Ecology, Physiology,
Human Anatomy, Molecular & Cellular Biology, Organic Chemistry, Physical Chemistry, Calculus, Biochemistry, Instrumental Methods of
Analysis, Quantitative Analysis, Linear Algebra.
3. JENNIFER ANNE GIBBONS, Ph.D.
2320 EDWARDS LANE. BEL AIR, MD 21015
(443) 401-9806 (cell)
jen.a.gibbons@gmail.com
PUBLICATIONS
Gibbons J.A., R. Balog, Rothwell, C., Ashley Melber, A., Benton, B., Hoard-Fruchey, H., Sekowski, J.W.
“Blood-based miRNA biomarkers of VX exposure” Manuscript in preparation
Carmany D., Walz A, Fu-Lian H, Benton B, Burnett D, Gibbons J.A., Noort D, Glaros T, Sekowski J.W.
“Activity Based Protein Profiling Leads to the Identification Novel Protein Targets for the Nerve Agent VX”
(2016) Manuscript submitted.
Gibbons, J.A. and Sekowski, J.W. “Evaluation of U.S. COTS Hand Held Assays to Detect Opiate Pain
Reliever Compounds in Multiple Biofluids.” (2016) ECBC Technical Report ECBC-TR-1409.
Gibbons, J.A., T. Glaros, P. Demond, S. Harvey, C. Chue. “Evaluation of a Recombinant Escherichia coli
Strain that Uses the Sarin Simulant Isopropylmethylphosphonic Acid (IMPA) as a Sole Carbon and
Phosphate Source” (2016) ECBC Technical Report ECBC-TR-1366.
Stromdahl E.Y., R. Nadolny, J.A. Gibbons, L. Aukland, M.A. Vince, C.E. Elkins, M.P. Murphy, G.J. Hickling,
M.W. Eshoo, H.E. Carolan, C.D. Crowder, M.A. Pilgard, S. Hamer “Borrelia burgdorferi not confirmed in
human-biting Amblyomma americanum ticks from the southeastern United States.” (2015) J. Clin. Microbiol.
53: 1697-704.
McCoy,, F., R. Darbandi, S. Chen, L. Eckard, K. Dodd, K. Jones, A.J. Baucum II, J.A. Gibbons, S-H. Lin,
R.J. Colbran, L.K. Nutt “Metabolic regulation of CamKII protein and caspases in Xenopus laevis egg
extracts.” (2013) J. Biol. Chem. 288: 8838-48.
Carter, J.C., R.A. Campbell, J.A. Gibbons, M.W. Gramling, A.S. Wolberg, F.C. Church “Enhanced Cell-
associated Fibrinolytic Pathway but not Coagulation Pathway Activity Contributes to Motility in Metastatic
Breast Cancer Cells” (2010) J. Thromb. Haemost. 8: 1323-32.
Wang, B. (Y.), D. Kim, J. Gibbons, X. Zeng, L. Pang, G. Quellhorst “RT2 miRNA PCR Arrays: The
Complete System for Genome-Wide and Pathway Focused microRNA Analysis” (2009) SABiosciences
Corp. Technical Article.
Nutt, L.K., M.R. Buchakjian, E. Gan, R. Darbandi, S-Y. Yoon, J.Q. Wu, Y.J. Miyamoto, J.A. Gibbons, J.L.
Andersen, C.D. Freel, W. Tang, C. He, M. Kurokawa, Y. Wang, S.S. Margolis, R.A. Fissore, and S.
Kornbluth “Metabolic control of oocyte apoptosis mediated by 14-3-3-regulated dephosphorylation of
caspase-2”. (2009) Dev. Cell 16:856-66.
Gibbons, J.A., L. Kozubowski, K. Tatchell, and S. Shenolikar “Functional analysis of human protein
phosphatase-1 isoforms expressed in the budding yeast, S. cerevisiae”. (2007) J. Biol. Chem. 282(30):
21838-47.
Gibbons, J.A., D.C. Weiser, and S. Shenolikar. “Mutations of a Hydrophobic Pocket in Protein Phosphatase
1 Catalytic Subunit Demonstrates Differences in Association of Regulators.” (2005) J. Biol. Chem. 280(16):
15903-11.
Aldridge, J.E.*, J.A. Gibbons*, M.M. Flaherty*, M.L. Kreider*, J.A. Romano*, E.D. Levin “Heterogeneity of
Toxicant Response: Sources of Human Variability.” (2003) Tox. Sci. 76: 3-20.
*co-first authors
4. JENNIFER ANNE GIBBONS, Ph.D.
2320 EDWARDS LANE. BEL AIR, MD 21015
(443) 401-9806 (cell)
jen.a.gibbons@gmail.com
PRESENTATIONS
1. Society of Toxicology, 2016 (Poster)
2. BioSciences Division Coffee with Colleagues, 2015 (3 Posters)
3. CBD S&T, 2015 (Poster)
4. ASM BioDefense, 2015 (Poster)
5. BioSciences Division Coffee with Colleagues, 2014 (Poster)
6. SABiosciences/QIAGEN Webinars, (1-3 per month, 2011-2013)
7. American Association of Immunologists, 2010 (Poster)
8. American Society of Hemostasis, 2009 (Poster)
9. Gordon Research Conference, 2008 (Poster)
10. Experimental Biology, 2007 Annual Meeting (Poster)
11. Experimental Biology, 2006 Annual Meeting (Poster)
12. EMBO Europhosphatases Meeting, 2005 (Poster)
13. FASEB Protein Phosphatases Meeting, 2004 (Poster)
14. American Crystallographic Meeting, 2001 (Poster)
SERVICE
1. Selection Panel for USAPHC 2016
2. Scientific Reviewer, DTRA Proposals 2015 - 2016
3. AOAC SPADA Working Group- SMPR Requirements 2015
4. BMC Genomics Reviewer 2015
5. ECBC Coffee with Colleagues Organizer 2015
6. BioSciences Division Coffee with Colleagues Organizer 2014
7. Maryland Science Bowl Judge 2013
8. STEM Career Day, Baltimore County Schools 2010
9. DNA Day Human Genome committee, UNC-CH 2007- 2008
10. Discussion leader for graduate student ethics seminar, UNC-CH 2007
11. DNA Day Presenter, T.W. Andrews High School, High Point, NC 2007
12. State High School Science Fair Judge, NC School of Science and Mathematics 2007
13. Poster Judge, Pathology Department, UNC-CH 2006 -2007
14. Scientific presenter, Expanding Your Horizons, NCSU 2005
HONORS AND AWARDS
Best new SABiosciences Product of the Year Finalist (Nano PreAmp) 2009
Best new SABiosciences Product of the Year Finalist (RT2 miRNA PCR Array) 2008
ASBMB Member 2007-present
AAAS Member 2006-present
Phi Delta Lambda member 2001-present