This document provides a summary of Dennis Allen Sheeter's education and work experience. He received a Ph.D. in Molecular Pathology from UC San Diego in 2002. Since then, he has held various positions in academia and industry, including as an advanced science instructor, independent scientific consultant, and research fellow. He has also published 10 journal articles focused on topics like HIV detection and pathogenesis.

1. Dennis Allen Sheeter
6420 Convict Hill Road Austin, Texas 78749 (805) 280-2307 dsheeter@smca.com
EDUCATION
Ph.D. Molecular Pathology University of California, San Diego 2002
M.S. Molecular Pathology University of California, San Diego 1998
B.S. Biochemistry and Cell Biology University of California, San Diego 1994
OVERVIEW
Ph.D. in Molecular Pathology from UC San Diego. Worked in top ranked virology laboratories at UCSD and The
Scripps Research Institute. Established one of the first genomics core facilities in the U.S. Pioneered real-time
PCR detection for infectious diseases using any of three different qPCR chemistries. Led R&D, manufacturing,
and marketing efforts for Amplifluor real-time PCR pathogen detection assays. Consulted for diagnostic and
pharmaceutical companies. Supported and managed instrumentation and consumable sales. Innovative scientist
and gifted instructor. Dedicated, loyal, and completely devoted to student’s long-term success and advancement
into higher education and scientific research.
WORK EXPERIENCE
Advanced Science Instructor, (2010 – Present)
St. Michael’s Catholic Academy, Austin, Texas
Head of School: Dr. Daniel Dolan
• Instructed courses in AP Physics, AP Chemistry, PreAP Chemistry, and General Chemistry
• Responsible for curriculum changes and new technology adoption
• Motivated and guided students to pursue science and medicine in college
Visiting Research Scholar, (2016)
Texas Institute for Discovery Education in Science (TIDES), University of Texas at Austin, Austin, Texas
Advisor: Dr. Erin Dolan, PhD
• Winter term sabbatical dedicated to developing innovative research driven experiential learning programs
Independent Scientific Consultant, (2013)
Asuragen, Research and Technology Development, Austin, Texas
Supervisors: Drs. Andrew Hadd and Gary Latham
• Developed a real time PCR-based detection strategy for fragile X syndrome and autism
Research Fellow, (2009 – 2010)
Institute for Cellular and Molecular Biology, University of Texas at Austin, Austin, Texas
Advisor: Dr. Alan Lambowitz, PhD
• Tested and validated novel thermostable reverse transcriptase enzymes in RT-qPCR
Adjunct Professor, (2009 – 2010)
Department of Biological Sciences, St. Edwards University, Austin, Texas
Department Head: Dr. William Quinn
• Designed course curriculum and instructed biology and general science courses and labs
Account Manager, Microarray and Real-Time PCR, (2008)
Agilent Technologies, Life Sciences and Chemical Analysis Division, Santa Clara, California
Supervisor: Daniel Kang
• Managed and supported the Agilent Bioanalyzer microfluidic system and the Stratagene product line of life
science instrumentation and bioreagents

2. Dennis Allen Sheeter Page 2
Field Applications Specialist, Sequence Detections Systems, (2007 – 2008)
Applied Biosystems, Sales and Support, Foster City, California
Supervisor: Dr. John Bowler Jr.
• Gave lectures, seminars, workshops, private consultations, and wet labs in the theory and application of
qPCR and real-time PCR instrumentation.
Scientist/ Supervisor, Molecular Diagnostics and Gene Regulation, (2004 – 2007)
Millipore Corporation, BioSciences Division (formally Chemicon International, Inc.), Temecula, California
Supervisor: Dr. Ruben Flores
• Led and supervised Amplifluor qPCR based molecular diagnostics effort, focusing on pathology, infectious
diseases, gene expression, ChIP, MSP, SNP, infectious diseases, RNAi, and universal detection.
Post-Doctoral Research, (2002 – 2004)
School of Medicine, University of California, San Diego, La Jolla, CA
Advisors: Drs. Joseph Wong and Davey Smith
Research Interest: Detection, Quantification and Phenotypic Assessment of Human Papilloma Virus in
Co-Infected HIV-1 Positive Patients
• Developed subtype specific, detection quantitative real-time PCR detection assay for HPV
Post-Doctoral Fellow, (2002 – 2004)
Molecular and Experimental Medicine, The Scripps Research Institute, La Jolla, California
Advisors: Drs. Bruce Torbett and John Elder
Funding: Competitive fellowship awarded from NIH/NINDS (2001-2005)
Research Interest 1: The Effects of the Broad-Based Protease Inhibitor TL-3 in FIV-C Infected Cats
Research Interest 2: Advancing the Art of Rational Drug Design for Retroviral Proteases
Independent Scientific Consultant, (1998 – 2003)
Intergen Company, Gaithersburg, Maryland
• Advanced the development of the Amplifluor real-time PCR detection system
Center for AIDS Research (CFAR), Genomics Core, U.C. San Diego, La Jolla, California
• Co-established the CFAR real-time PCR core facility, using multiple real-time PCR platforms: Amplifluor,
SYBR, and TaqMan
PhD Dissertation, (1996 – 2002)
Title: Pathogenic Consequences of Host Cell Gene Modulation Induced by HIV-1
Molecular Pathology Program, School of Medicine, University of California, San Diego, La Jolla, CA
Advisor: Douglas Richman, Professor of Pathology and Medicine, University of California, San Diego.
Research Interest: Synergizing the newly developed field of Genomics to the study of HIV-1
• Investigated the molecular mechanisms of virus/ host cell interactions that influence virus replication and
pathogenesis in HIV-1 infected T cells
Senior Research Associate II, (1996 – 1997)
School of Medicine, U.C. San Diego, La Jolla, CA
Advisors: Drs. David Looney and Jacques Corbeil
Research Interest: Quantification of Cellular Induction of CXCR4 and CCR5 Under Various Stimuli

3. Dennis Allen Sheeter Page 3
Laboratory Manager, (1995 – 1996)
Cancer Center, U.C. San Diego, La Jolla, CA
Advisor: Dr. Joseph Voland
Research Interest: The Structure and Function of CD-39: A Putative Tumor Suppressor
Chemist II, GMP Manufacturing; Quality Assurance and Control, (1994 – 1995)
Chiron Mimotopes Peptide Systems, San Diego, California
Supervisor: Dr. Jeanick Pascal
JOURNAL PUBLICATIONS * Contributed equally to this work
1. Tschan MP, Federzoni EA, Haimovici A, Britschgi C, Moser BA, Jin J, Reddy VA, Sheeter DA, Fischer KM,
Sun P, Torbett BE. Human DMTF1β antagonizes DMTF1α regulation of the p14(ARF) tumor suppressor and
promotes cellular proliferation. Biochim Biophys Acta. 2015 Sep;1849(9):1198-208.
2. Mohr S, Ghanem E, Smith W, Sheeter D, Qin Y, King O, Polioudakis D, Iyer VR, Hunicke-Smith S, Swamy
S, Kuersten S, Lambowitz AM. Thermostable group II intron reverse transcriptase fusion proteins and their use
in cDNA synthesis and next-generation RNA sequencing. RNA. 2013 Jul;19(7):958-70.
3. Pilar Blancafort, Mario P. Tschan, Sharon Bergquist, Daniel Guthy, Arndt Brachat, Dennis A. Sheeter, Bruce
E. Torbett, Dirk Edrmann and Carlos F. Barbas III. Modulation of drug resistance by artificial trancription
factors. Mol Cancer Ther. 2008 Mar;7(3):688-97. Epub 2008 Mar 4.
4. Manuel ER, Charini WA, Sen P, Peyerl FW, Kuroda MJ, Schmitz JE, Autissier P, Sheeter DA, Torbett BE,
Letvin NL. Contribution of TCR Repertoire Breadth to the Dominance of Epitope-Specific CD8+ T
Lymphocyte Responses. J Virol. 2006 Oct 11;
5. Chatterji U, Bobardt MD, Gaskill P, Sheeter D, Fox H, Gallay PA. Trim5alpha accelerates degradation of
cytosolic capsid associated with productive HIV-1 entry. J Biol Chem. 2006 Oct 6;
6. de Rozières S, Swan CH, Sheeter DA, Clingerman KJ, Lin YC, Huitron-Resendiz S, Henriksen S, Torbett BE,
Elder JH. Assessment of FIV-C Infection of Cats as a Function of Treatment with the Protease Inhibitor, TL-3.
Retrovirology. 2004 Nov 19, 1:38
7. Kutilek V* and Sheeter D*, Elder J, and Torbett B. Is Resistance Futile? Current Drug Targets - Infectious
Disorders. 2003, (3), 295-309.
8. Sheeter D, Du P, Rought S, Richman D, Corbeil J. Surface CD4 Expression Modulated by a Cellular Factor
induced by HIV-1 Infection. AIDS Res Hum Retroviruses 2003 Feb;19(2):117-23
9. Corbeil J, Sheeter D, Genini D, Rought S, Leoni L, Du P, Ferguson M, Masys DR, Welsh JB, Fink JL, Sasik
R, Huang D, Drenkow J, Richman DD, Gingeras T. Temporal gene regulation during HIV-1 infection of
human CD4+ T cells. Genome Res. 2001 Jul;11(7):1198-204.
10. Genini D* and Sheeter D*, Rought S, Zaunders JJ, Susin SA, Kroemer G, Richman DD, Carson DA, Corbeil J,
Leoni LM. HIV induces lymphocyte apoptosis by a p53-initiated, mitochondrial-mediated mechanism. FASEB
J. 2001 Jan;15(1):5-6.