SlideShare a Scribd company logo
What are designer drugs?
New wave
of psychoactive compounds
Jerzy Bukowczan
Department of Pharmacognosy and Phytochemistry
Medical University of Silesia
supervisor: dr hab. Ilona Kaczmarczyk-Sedlak
Introduction
 Marketed legally in shops.
Caused acute poisonings and deaths.
 Banned in 2010.
 Came back under many names:
„designer drugs”,
„research chemicals”,
„legal highs”,
„bath salts”,
„cleaning agents”,
„dopalacze”.
Designer drugs – possible dangers
 Unknown contents of „legal high” products
• dangerous mixes (even with alcohol or caffeine)
• difficult hospital treatment
Designer drugs – possible dangers
 Unknown contents of „legal high” products
• dangerous mixes (even with alcohol or caffeine)
• difficult hospital treatment
 No valuable information about dosage
• acute overdose and anaphylaxis
• beginners try experienced users’ doses
Designer drugs – possible dangers
 Unknown contents of „legal high” products
• dangerous mixes (even with alcohol or caffeine)
• difficult hospital treatment
 No valuable information about dosage
• acute overdose and anaphylaxis
• beginners try experienced users’ doses
 OTC medicine also used as „legal highs”
Material and methods
 Literature review about „designer drugs”:
research, pharmacology and poisoning treatment
 Internet sites analysis on ways to get „legally high”
 Interviews with users
Designer drugs - classification
Stimulants
Hallucinogens
Cannabinoids
Sedatives
Stimulants
Phenetylamines
cathinones
2C-s
amphetamines
Piperazines
Plant-derived hallucinogens
Argyreia nervosa
hawaiian woodrose
LSA
Mitragyna speciosa
krathom
mitragynine
Mimosa tenuiflora
DMT
Synthetic hallucinogens
Tryptamines
Phenethylamines
Dissociatives
ketamin and PCP derivatives
Synthetic cannabinoids
Indole derivatives
so called JWH group
Phenols
Classical
based on THC
Sedatives
Barbiturates and benzodiazepines
not labeled as medicine
(i. e. etizolam)
GHB and derivatives:
GBL, GHV, GVL
Other ways of getting high...
 Stimulants
pseudoephedrine (Sudafed, Acatar, Clarinase)
methcathinone
 Hallucinogens
• deliriants: dimenhydrinate (Aviomarin)
diphenhydramine (Apap Noc)
benzydamine (Tantum Rosa)
• dissociatives: dextrometorphan (Acodin, Tussidex)
 Sedatives
codeine (Thiocodin, Neoazarina, Pini)
allobarbital (Stomach drops with pabialgine)
Conclusions
New psychoactive drugs are designed constantly
It is hardly possible to control them all
Pharmacists should be aware of every possible
usage of certain medicines and chemicals
Patient education is a crucial matter
Thank you for your attention!
References:
• Jolanta B. Zawilska.„Legal Highs” – New Players in the Old Drama. Current Drug Abuse
Reviews, 2011, 4, 122-130.
• Sebastian Dresen, Nerea Ferreiros, Michael Putz, Folker Westphal,e Ralf Zimmermannb,
Volker Auwarter. Monitoring of herbal mixtures potentially containing synthetic cannabinoids
as psychoactive compounds. J. Mass. Spectrom. 2010, 45, 1186–1194.
• Monika Ciechomska, Michał Woźniakiewicz, Renata Wietecha–Posłuszny. Activity and bio
transformatio n of three synthetic “legal highs ”: mephedrone, methylone and 3,4-methyle
nodioxypyro valerone Problems of Forensic Sciences 2012, vol. 89, 71–85.
• Dorota KLIMASZYK, Katarzyna NAWROCKA. ACUTE INTOXICATIONS WITH
“LEGAL HIGHS” AND RECREATIONAL DRUGS – CHALLENGES FOR
TOXICOLOGISTS. Problems of Forensic Sciences 2009, vol. LXXX, 450–458.
• Piotr Hydzik, Ewa Gomółka, Adrianna Sulka, Sylwia Cudzich-Czop. Acute methoxetamine
poisoning – case report. Problems of Forensic Sciences 2012, vol. 91, 235–242.
• Dariusz Zuba, Bogumila Byrska, Martyna Maciow. Comparison of “herbal highs”
composition. Anal Bioanal Chem (2011) 400:119–126.

More Related Content

What's hot

Ccps anti drug campaign
Ccps anti drug campaignCcps anti drug campaign
Ccps anti drug campaign
RomarMendoza1
 
5.1 medical toxicant
5.1 medical toxicant5.1 medical toxicant
5.1 medical toxicant
Bule Hora University
 
Introduction O General Toxicology
Introduction O General ToxicologyIntroduction O General Toxicology
Introduction O General Toxicology
Sama Queen
 
Pharma 2016
Pharma 2016Pharma 2016
Pharma 2016
Khalid Aftab, Ph.D.
 
Principles of Toxicology for Dietetics
Principles of Toxicology for DieteticsPrinciples of Toxicology for Dietetics
Principles of Toxicology for Dietetics
Amna Medani
 
Drug Addiction
Drug AddictionDrug Addiction
Drug Addiction
Mohsin Aziz
 
Medicinal chemistry unit1&3
Medicinal chemistry unit1&3Medicinal chemistry unit1&3
Medicinal chemistry unit1&3
bvocmithilesh
 
Rad 104 hospital practice and care of patients 3 drugs & contrast 2016
Rad 104 hospital practice and care of patients 3  drugs & contrast 2016Rad 104 hospital practice and care of patients 3  drugs & contrast 2016
Rad 104 hospital practice and care of patients 3 drugs & contrast 2016
sehlawi
 
Basic introduction to Pharmacology
Basic introduction to PharmacologyBasic introduction to Pharmacology
Basic introduction to Pharmacology
Shagufta Farooqui
 
IVMS-CNS Depressants II /Drugs of Abuse IV-Ethanol
IVMS-CNS Depressants II /Drugs of Abuse IV-Ethanol IVMS-CNS Depressants II /Drugs of Abuse IV-Ethanol
IVMS-CNS Depressants II /Drugs of Abuse IV-Ethanol
Imhotep Virtual Medical School
 
4. pesticides
4. pesticides4. pesticides
4. pesticides
Bule Hora University
 
Principle o f Toxicology and ADR
Principle o f Toxicology and ADRPrinciple o f Toxicology and ADR
Principle o f Toxicology and ADR
Vithya sekar
 
21st Century Street Drug Pharmacology New Drugs Of The 2nd Decade
21st Century Street Drug Pharmacology New Drugs Of The 2nd Decade21st Century Street Drug Pharmacology New Drugs Of The 2nd Decade
21st Century Street Drug Pharmacology New Drugs Of The 2nd Decade
rwebber
 
Detection of addiction in medical professionals -an eye opener
Detection of addiction in medical professionals -an eye openerDetection of addiction in medical professionals -an eye opener
Detection of addiction in medical professionals -an eye opener
GGS Medical College/Baba Farid Univ.of Health Sciences.
 
Toxicology and its basic prinicples
Toxicology and its basic prinicplesToxicology and its basic prinicples
Toxicology and its basic prinicples
Koppala RVS Chaitanya
 
Introduction to toxicology
 Introduction to toxicology  Introduction to toxicology
Introduction to toxicology
Ratnabro
 
Motherisk round herbal medicine/최준식 교수
Motherisk round herbal medicine/최준식 교수Motherisk round herbal medicine/최준식 교수
Motherisk round herbal medicine/최준식 교수
mothersafe
 
Introduction to General toxicology
Introduction to General toxicologyIntroduction to General toxicology
Introduction to General toxicology
BADAR UDDIN UMAR
 
Drug detoxication, Tolerance, Intolerance, Combined effects, Dosage, Classifi...
Drug detoxication, Tolerance, Intolerance, Combined effects, Dosage, Classifi...Drug detoxication, Tolerance, Intolerance, Combined effects, Dosage, Classifi...
Drug detoxication, Tolerance, Intolerance, Combined effects, Dosage, Classifi...
Deepthi P Ramachandran
 
Introduction to toxicology gases and metals
Introduction to toxicology gases and metalsIntroduction to toxicology gases and metals
Introduction to toxicology gases and metals
NITISH SHAH
 

What's hot (20)

Ccps anti drug campaign
Ccps anti drug campaignCcps anti drug campaign
Ccps anti drug campaign
 
5.1 medical toxicant
5.1 medical toxicant5.1 medical toxicant
5.1 medical toxicant
 
Introduction O General Toxicology
Introduction O General ToxicologyIntroduction O General Toxicology
Introduction O General Toxicology
 
Pharma 2016
Pharma 2016Pharma 2016
Pharma 2016
 
Principles of Toxicology for Dietetics
Principles of Toxicology for DieteticsPrinciples of Toxicology for Dietetics
Principles of Toxicology for Dietetics
 
Drug Addiction
Drug AddictionDrug Addiction
Drug Addiction
 
Medicinal chemistry unit1&3
Medicinal chemistry unit1&3Medicinal chemistry unit1&3
Medicinal chemistry unit1&3
 
Rad 104 hospital practice and care of patients 3 drugs & contrast 2016
Rad 104 hospital practice and care of patients 3  drugs & contrast 2016Rad 104 hospital practice and care of patients 3  drugs & contrast 2016
Rad 104 hospital practice and care of patients 3 drugs & contrast 2016
 
Basic introduction to Pharmacology
Basic introduction to PharmacologyBasic introduction to Pharmacology
Basic introduction to Pharmacology
 
IVMS-CNS Depressants II /Drugs of Abuse IV-Ethanol
IVMS-CNS Depressants II /Drugs of Abuse IV-Ethanol IVMS-CNS Depressants II /Drugs of Abuse IV-Ethanol
IVMS-CNS Depressants II /Drugs of Abuse IV-Ethanol
 
4. pesticides
4. pesticides4. pesticides
4. pesticides
 
Principle o f Toxicology and ADR
Principle o f Toxicology and ADRPrinciple o f Toxicology and ADR
Principle o f Toxicology and ADR
 
21st Century Street Drug Pharmacology New Drugs Of The 2nd Decade
21st Century Street Drug Pharmacology New Drugs Of The 2nd Decade21st Century Street Drug Pharmacology New Drugs Of The 2nd Decade
21st Century Street Drug Pharmacology New Drugs Of The 2nd Decade
 
Detection of addiction in medical professionals -an eye opener
Detection of addiction in medical professionals -an eye openerDetection of addiction in medical professionals -an eye opener
Detection of addiction in medical professionals -an eye opener
 
Toxicology and its basic prinicples
Toxicology and its basic prinicplesToxicology and its basic prinicples
Toxicology and its basic prinicples
 
Introduction to toxicology
 Introduction to toxicology  Introduction to toxicology
Introduction to toxicology
 
Motherisk round herbal medicine/최준식 교수
Motherisk round herbal medicine/최준식 교수Motherisk round herbal medicine/최준식 교수
Motherisk round herbal medicine/최준식 교수
 
Introduction to General toxicology
Introduction to General toxicologyIntroduction to General toxicology
Introduction to General toxicology
 
Drug detoxication, Tolerance, Intolerance, Combined effects, Dosage, Classifi...
Drug detoxication, Tolerance, Intolerance, Combined effects, Dosage, Classifi...Drug detoxication, Tolerance, Intolerance, Combined effects, Dosage, Classifi...
Drug detoxication, Tolerance, Intolerance, Combined effects, Dosage, Classifi...
 
Introduction to toxicology gases and metals
Introduction to toxicology gases and metalsIntroduction to toxicology gases and metals
Introduction to toxicology gases and metals
 

Viewers also liked

Vogl Presentation
Vogl PresentationVogl Presentation
Vogl Presentation
ronancoffey
 
Contemporary
ContemporaryContemporary
Contemporary
sinaloa1
 
Rethinking Education in the Age of Technology
Rethinking Education in the Age of TechnologyRethinking Education in the Age of Technology
Rethinking Education in the Age of Technology
Michael Larson
 
Sjovagen rapport sammanfattn
Sjovagen rapport sammanfattnSjovagen rapport sammanfattn
Sjovagen rapport sammanfattnafalk
 
Snsの楽しみ方
Snsの楽しみ方Snsの楽しみ方
Snsの楽しみ方Hitoshi Naya
 
Oculus Game Jam in Japan #3
Oculus Game Jam in Japan #3Oculus Game Jam in Japan #3
Oculus Game Jam in Japan #3
Shinya Hayakawa
 
Hcl cdc project
Hcl cdc projectHcl cdc project
Hcl cdc project
Rahul Rai
 
12 days of Christmas
12 days of Christmas12 days of Christmas
12 days of Christmas
sdefazio17
 
HCD-net ワークショップ「ユーザーエクスペリエンスデザインのためのストーリーテリング」 part3 ストーリーを作る
HCD-net ワークショップ「ユーザーエクスペリエンスデザインのためのストーリーテリング」 part3 ストーリーを作るHCD-net ワークショップ「ユーザーエクスペリエンスデザインのためのストーリーテリング」 part3 ストーリーを作る
HCD-net ワークショップ「ユーザーエクスペリエンスデザインのためのストーリーテリング」 part3 ストーリーを作るux_tokyo
 
CMHC Kingston 2012
CMHC Kingston 2012CMHC Kingston 2012
CMHC Kingston 2012
WinterFinancial
 
English project kawther
English project kawtherEnglish project kawther
English project kawther
201104514
 
Conditionals
ConditionalsConditionals
Conditionals
bensu70
 
οι θρησκείες του κόσμου για τα ναρκωτικά και το αλκοόλ
οι θρησκείες του κόσμου για τα ναρκωτικά και το αλκοόλοι θρησκείες του κόσμου για τα ναρκωτικά και το αλκοόλ
οι θρησκείες του κόσμου για τα ναρκωτικά και το αλκοόλparaskevit
 
pengantar logika-dan_algoritma
pengantar logika-dan_algoritmapengantar logika-dan_algoritma
pengantar logika-dan_algoritmarejeki tobing
 
Apuvälinepalveluiden tutkimuksesta Heidi Anttila
Apuvälinepalveluiden tutkimuksesta Heidi Anttila Apuvälinepalveluiden tutkimuksesta Heidi Anttila
Apuvälinepalveluiden tutkimuksesta Heidi Anttila
Heidi Anttila
 
GPS GLONASS
GPS GLONASSGPS GLONASS
GPS GLONASS
Hyppolite Panin
 
Martyanovy shakleiny voinovy
Martyanovy shakleiny voinovyMartyanovy shakleiny voinovy
Martyanovy shakleiny voinovyDemanessa
 
Depression ppt
Depression pptDepression ppt
Depression ppt
Najad Salahudeen
 
Презентація щодо реформування системи надання адміністративних послуг
Презентація щодо реформування системи надання адміністративних послугПрезентація щодо реформування системи надання адміністративних послуг
Презентація щодо реформування системи надання адміністративних послуг
Olena Ursu
 

Viewers also liked (20)

Vogl Presentation
Vogl PresentationVogl Presentation
Vogl Presentation
 
Contemporary
ContemporaryContemporary
Contemporary
 
Rethinking Education in the Age of Technology
Rethinking Education in the Age of TechnologyRethinking Education in the Age of Technology
Rethinking Education in the Age of Technology
 
Sjovagen rapport sammanfattn
Sjovagen rapport sammanfattnSjovagen rapport sammanfattn
Sjovagen rapport sammanfattn
 
Snsの楽しみ方
Snsの楽しみ方Snsの楽しみ方
Snsの楽しみ方
 
Oculus Game Jam in Japan #3
Oculus Game Jam in Japan #3Oculus Game Jam in Japan #3
Oculus Game Jam in Japan #3
 
Hcl cdc project
Hcl cdc projectHcl cdc project
Hcl cdc project
 
12 days of Christmas
12 days of Christmas12 days of Christmas
12 days of Christmas
 
HCD-net ワークショップ「ユーザーエクスペリエンスデザインのためのストーリーテリング」 part3 ストーリーを作る
HCD-net ワークショップ「ユーザーエクスペリエンスデザインのためのストーリーテリング」 part3 ストーリーを作るHCD-net ワークショップ「ユーザーエクスペリエンスデザインのためのストーリーテリング」 part3 ストーリーを作る
HCD-net ワークショップ「ユーザーエクスペリエンスデザインのためのストーリーテリング」 part3 ストーリーを作る
 
CMHC Kingston 2012
CMHC Kingston 2012CMHC Kingston 2012
CMHC Kingston 2012
 
English project kawther
English project kawtherEnglish project kawther
English project kawther
 
Conditionals
ConditionalsConditionals
Conditionals
 
Generation y
Generation   yGeneration   y
Generation y
 
οι θρησκείες του κόσμου για τα ναρκωτικά και το αλκοόλ
οι θρησκείες του κόσμου για τα ναρκωτικά και το αλκοόλοι θρησκείες του κόσμου για τα ναρκωτικά και το αλκοόλ
οι θρησκείες του κόσμου για τα ναρκωτικά και το αλκοόλ
 
pengantar logika-dan_algoritma
pengantar logika-dan_algoritmapengantar logika-dan_algoritma
pengantar logika-dan_algoritma
 
Apuvälinepalveluiden tutkimuksesta Heidi Anttila
Apuvälinepalveluiden tutkimuksesta Heidi Anttila Apuvälinepalveluiden tutkimuksesta Heidi Anttila
Apuvälinepalveluiden tutkimuksesta Heidi Anttila
 
GPS GLONASS
GPS GLONASSGPS GLONASS
GPS GLONASS
 
Martyanovy shakleiny voinovy
Martyanovy shakleiny voinovyMartyanovy shakleiny voinovy
Martyanovy shakleiny voinovy
 
Depression ppt
Depression pptDepression ppt
Depression ppt
 
Презентація щодо реформування системи надання адміністративних послуг
Презентація щодо реформування системи надання адміністративних послугПрезентація щодо реформування системи надання адміністративних послуг
Презентація щодо реформування системи надання адміністративних послуг
 

Similar to J. bukowczan dopalacze v1.0

Non-Dependence Producing Drugs in the Treatment of Addictions
Non-Dependence Producing Drugs in the Treatment of AddictionsNon-Dependence Producing Drugs in the Treatment of Addictions
Non-Dependence Producing Drugs in the Treatment of Addictions
Brendan Quinn
 
Drug design and discovery ppt
Drug design and discovery pptDrug design and discovery ppt
Drug design and discovery ppt
Dr NEETHU ASOKAN
 
Intro. p'cology
Intro. p'cologyIntro. p'cology
Intro. p'cology
Rani Dhole
 
Sources of materia medica pdf.pdf
Sources of materia medica pdf.pdfSources of materia medica pdf.pdf
Sources of materia medica pdf.pdf
chanikyasrr
 
Prevalence, Types and Impact of Drug Abuse
Prevalence, Types and Impact of Drug Abuse  Prevalence, Types and Impact of Drug Abuse
Prevalence, Types and Impact of Drug Abuse
Smriti Arora
 
intro_to_addiction_merlo
intro_to_addiction_merlointro_to_addiction_merlo
intro_to_addiction_merlo
mmutahir
 
Issues Involving Drugs and Traffic Safety
Issues Involving Drugs and Traffic SafetyIssues Involving Drugs and Traffic Safety
Issues Involving Drugs and Traffic Safety
Texas A&M Transportation Institute
 
Pharmacology and drugs
Pharmacology and drugsPharmacology and drugs
Pharmacology and drugs
Awais Liaqat
 
Management of poison(Emergency Medicine)
Management of poison(Emergency Medicine)Management of poison(Emergency Medicine)
Management of poison(Emergency Medicine)
kalyan ram
 
Drug Discovery New Drug Development Process
Drug Discovery New Drug Development ProcessDrug Discovery New Drug Development Process
Drug Discovery New Drug Development Process
Prof. Dr. Basavaraj Nanjwade
 
Dealing with Substance Abuse in the Library: A Guide to Helping Patrons and t...
Dealing with Substance Abuse in the Library: A Guide to Helping Patrons and t...Dealing with Substance Abuse in the Library: A Guide to Helping Patrons and t...
Dealing with Substance Abuse in the Library: A Guide to Helping Patrons and t...
ALATechSource
 
Dealing with Substance Abuse in the Library: A Guide to Helping Patrons and t...
Dealing with Substance Abuse in the Library: A Guide to Helping Patrons and t...Dealing with Substance Abuse in the Library: A Guide to Helping Patrons and t...
Dealing with Substance Abuse in the Library: A Guide to Helping Patrons and t...
ALATechSource
 
Say no to Addiction- Drugs and Types
Say no to Addiction- Drugs and TypesSay no to Addiction- Drugs and Types
Say no to Addiction- Drugs and Types
Dr.K Madhuri
 
Homeopathy Empirical Medicine
Homeopathy   Empirical MedicineHomeopathy   Empirical Medicine
Homeopathy Empirical Medicine
Alison Robinson
 
General Consideration of Toxicology.pptx
General Consideration of Toxicology.pptxGeneral Consideration of Toxicology.pptx
General Consideration of Toxicology.pptx
ESIC Medical College, Kalaburagi
 
Substance use disorder 2nd part
Substance use disorder 2nd partSubstance use disorder 2nd part
Substance use disorder 2nd part
Soheir ELghonemy
 
Bath Salts and New Drugs
Bath Salts and New DrugsBath Salts and New Drugs
Bath Salts and New Drugs
Laurence Karper
 
Consequências e Tipos de Drogas
Consequências e Tipos de DrogasConsequências e Tipos de Drogas
Consequências e Tipos de Drogas
Diana Sousa
 
Poisoning in Children by Dr Shamavu Gabriel .pptx
Poisoning in Children by Dr Shamavu Gabriel .pptxPoisoning in Children by Dr Shamavu Gabriel .pptx
Poisoning in Children by Dr Shamavu Gabriel .pptx
Gabriel Shamavu
 
Drug discoveries by serendipity
Drug discoveries by serendipityDrug discoveries by serendipity
Drug discoveries by serendipity
Ramisa Tasnia
 

Similar to J. bukowczan dopalacze v1.0 (20)

Non-Dependence Producing Drugs in the Treatment of Addictions
Non-Dependence Producing Drugs in the Treatment of AddictionsNon-Dependence Producing Drugs in the Treatment of Addictions
Non-Dependence Producing Drugs in the Treatment of Addictions
 
Drug design and discovery ppt
Drug design and discovery pptDrug design and discovery ppt
Drug design and discovery ppt
 
Intro. p'cology
Intro. p'cologyIntro. p'cology
Intro. p'cology
 
Sources of materia medica pdf.pdf
Sources of materia medica pdf.pdfSources of materia medica pdf.pdf
Sources of materia medica pdf.pdf
 
Prevalence, Types and Impact of Drug Abuse
Prevalence, Types and Impact of Drug Abuse  Prevalence, Types and Impact of Drug Abuse
Prevalence, Types and Impact of Drug Abuse
 
intro_to_addiction_merlo
intro_to_addiction_merlointro_to_addiction_merlo
intro_to_addiction_merlo
 
Issues Involving Drugs and Traffic Safety
Issues Involving Drugs and Traffic SafetyIssues Involving Drugs and Traffic Safety
Issues Involving Drugs and Traffic Safety
 
Pharmacology and drugs
Pharmacology and drugsPharmacology and drugs
Pharmacology and drugs
 
Management of poison(Emergency Medicine)
Management of poison(Emergency Medicine)Management of poison(Emergency Medicine)
Management of poison(Emergency Medicine)
 
Drug Discovery New Drug Development Process
Drug Discovery New Drug Development ProcessDrug Discovery New Drug Development Process
Drug Discovery New Drug Development Process
 
Dealing with Substance Abuse in the Library: A Guide to Helping Patrons and t...
Dealing with Substance Abuse in the Library: A Guide to Helping Patrons and t...Dealing with Substance Abuse in the Library: A Guide to Helping Patrons and t...
Dealing with Substance Abuse in the Library: A Guide to Helping Patrons and t...
 
Dealing with Substance Abuse in the Library: A Guide to Helping Patrons and t...
Dealing with Substance Abuse in the Library: A Guide to Helping Patrons and t...Dealing with Substance Abuse in the Library: A Guide to Helping Patrons and t...
Dealing with Substance Abuse in the Library: A Guide to Helping Patrons and t...
 
Say no to Addiction- Drugs and Types
Say no to Addiction- Drugs and TypesSay no to Addiction- Drugs and Types
Say no to Addiction- Drugs and Types
 
Homeopathy Empirical Medicine
Homeopathy   Empirical MedicineHomeopathy   Empirical Medicine
Homeopathy Empirical Medicine
 
General Consideration of Toxicology.pptx
General Consideration of Toxicology.pptxGeneral Consideration of Toxicology.pptx
General Consideration of Toxicology.pptx
 
Substance use disorder 2nd part
Substance use disorder 2nd partSubstance use disorder 2nd part
Substance use disorder 2nd part
 
Bath Salts and New Drugs
Bath Salts and New DrugsBath Salts and New Drugs
Bath Salts and New Drugs
 
Consequências e Tipos de Drogas
Consequências e Tipos de DrogasConsequências e Tipos de Drogas
Consequências e Tipos de Drogas
 
Poisoning in Children by Dr Shamavu Gabriel .pptx
Poisoning in Children by Dr Shamavu Gabriel .pptxPoisoning in Children by Dr Shamavu Gabriel .pptx
Poisoning in Children by Dr Shamavu Gabriel .pptx
 
Drug discoveries by serendipity
Drug discoveries by serendipityDrug discoveries by serendipity
Drug discoveries by serendipity
 

J. bukowczan dopalacze v1.0

  • 1. What are designer drugs? New wave of psychoactive compounds Jerzy Bukowczan Department of Pharmacognosy and Phytochemistry Medical University of Silesia supervisor: dr hab. Ilona Kaczmarczyk-Sedlak
  • 2. Introduction  Marketed legally in shops. Caused acute poisonings and deaths.  Banned in 2010.  Came back under many names: „designer drugs”, „research chemicals”, „legal highs”, „bath salts”, „cleaning agents”, „dopalacze”.
  • 3. Designer drugs – possible dangers  Unknown contents of „legal high” products • dangerous mixes (even with alcohol or caffeine) • difficult hospital treatment
  • 4. Designer drugs – possible dangers  Unknown contents of „legal high” products • dangerous mixes (even with alcohol or caffeine) • difficult hospital treatment  No valuable information about dosage • acute overdose and anaphylaxis • beginners try experienced users’ doses
  • 5. Designer drugs – possible dangers  Unknown contents of „legal high” products • dangerous mixes (even with alcohol or caffeine) • difficult hospital treatment  No valuable information about dosage • acute overdose and anaphylaxis • beginners try experienced users’ doses  OTC medicine also used as „legal highs”
  • 6. Material and methods  Literature review about „designer drugs”: research, pharmacology and poisoning treatment  Internet sites analysis on ways to get „legally high”  Interviews with users
  • 7. Designer drugs - classification Stimulants Hallucinogens Cannabinoids Sedatives
  • 9. Plant-derived hallucinogens Argyreia nervosa hawaiian woodrose LSA Mitragyna speciosa krathom mitragynine Mimosa tenuiflora DMT
  • 11. Synthetic cannabinoids Indole derivatives so called JWH group Phenols Classical based on THC
  • 12. Sedatives Barbiturates and benzodiazepines not labeled as medicine (i. e. etizolam) GHB and derivatives: GBL, GHV, GVL
  • 13. Other ways of getting high...  Stimulants pseudoephedrine (Sudafed, Acatar, Clarinase) methcathinone  Hallucinogens • deliriants: dimenhydrinate (Aviomarin) diphenhydramine (Apap Noc) benzydamine (Tantum Rosa) • dissociatives: dextrometorphan (Acodin, Tussidex)  Sedatives codeine (Thiocodin, Neoazarina, Pini) allobarbital (Stomach drops with pabialgine)
  • 14. Conclusions New psychoactive drugs are designed constantly It is hardly possible to control them all Pharmacists should be aware of every possible usage of certain medicines and chemicals Patient education is a crucial matter
  • 15. Thank you for your attention! References: • Jolanta B. Zawilska.„Legal Highs” – New Players in the Old Drama. Current Drug Abuse Reviews, 2011, 4, 122-130. • Sebastian Dresen, Nerea Ferreiros, Michael Putz, Folker Westphal,e Ralf Zimmermannb, Volker Auwarter. Monitoring of herbal mixtures potentially containing synthetic cannabinoids as psychoactive compounds. J. Mass. Spectrom. 2010, 45, 1186–1194. • Monika Ciechomska, Michał Woźniakiewicz, Renata Wietecha–Posłuszny. Activity and bio transformatio n of three synthetic “legal highs ”: mephedrone, methylone and 3,4-methyle nodioxypyro valerone Problems of Forensic Sciences 2012, vol. 89, 71–85. • Dorota KLIMASZYK, Katarzyna NAWROCKA. ACUTE INTOXICATIONS WITH “LEGAL HIGHS” AND RECREATIONAL DRUGS – CHALLENGES FOR TOXICOLOGISTS. Problems of Forensic Sciences 2009, vol. LXXX, 450–458. • Piotr Hydzik, Ewa Gomółka, Adrianna Sulka, Sylwia Cudzich-Czop. Acute methoxetamine poisoning – case report. Problems of Forensic Sciences 2012, vol. 91, 235–242. • Dariusz Zuba, Bogumila Byrska, Martyna Maciow. Comparison of “herbal highs” composition. Anal Bioanal Chem (2011) 400:119–126.