On November 10, a meeting about the role of IVUS on vascular surgery (Chairman Prof. Andrea Stella) took place in Bologna. The meeting was an excellent opportunity to discuss about the role of the IVUS in every field of vascular surgery: type B dissections, AAA's, PAOD, popliteal aneurysms and chronic venous obstructions.
By: Seshadri Raju, MD, FACS
Visit VeinGlobal at http://www.veinglobal.com/ for more presentations and videos on this topic, or for more information on venous disease news, education and research.
By: Seshadri Raju, MD, FACS
Visit VeinGlobal at http://www.veinglobal.com/ for more presentations and videos on this topic, or for more information on venous disease news, education and research.
Imaging centres in Mumbai iScan Imaging is therefore very important to choose a reputed and trusted service when it comes to diagnosis of illnesses & injuries and Ct scan centres in mumbai.
A randomised comparison of reservoir-based polymer-free amphilimus-eluting stents versus everolimus-eluting stents in patients with diabetes mellitus: the RESERVOIR clinical trial
Imaging centres in Mumbai iScan Imaging is therefore very important to choose a reputed and trusted service when it comes to diagnosis of illnesses & injuries and Ct scan centres in mumbai.
A randomised comparison of reservoir-based polymer-free amphilimus-eluting stents versus everolimus-eluting stents in patients with diabetes mellitus: the RESERVOIR clinical trial
SELDINGER TECHNIQUE & INTERVENTIONAL RADIOLOGYRiyas M K
its a basic introduction about Seldinger technique and Intervetional radiology.In interventional radiology, procedures generally start with the Seldinger technique to access the vasculature, using a needle through which a guidewire is inserted, followed by navigation of catheters within the vessels.
Ann Vasc Surg 2012; 26: 141-148-Selected technique- Funnel Technique for EVAR: ‘‘A Way Out’’ for Abdominal Aortic Aneurisms With Ectatic Proximal Necks
(Chirurgia Vascolare-ULSS 15 Alta Padovana)
(Vascular Surgery -ULSS 15 Alta Padovana)
Intracoronary Imaging – when to use, how to use and how to interpret the imagesEuro CTO Club
Intracoronary Imaging – when to use, how to use and how to
interpret the images
Javier Escaned, Spain
The Experts “Live” Workshop 2017
Saturday, September 16th, 2017
Vascular Access Part 1: Reducing risk and increasing catheter longevityCoda Change
The aim of having a structured decision matrix in the approach to vascular access is to reduce catheter-associated complications and to increase device longevity. There are over 15,000 central venous catheters placed in Australia annually. The actual insertion process for placing a central line only accounts for a small part of the 'life span' of that line (approximately 1%), but the choices made at the time of insertion have a huge impact on the longevity of the device and the associated complications. In this introductory talk Evan Alexandrou outlines the top ten tips for reducing complications associated with vascular access devices:
1. Always use ultrasound: Never do a blind puncture
2. Ensure with the site chosen for the catheter that it exits the skin on a flat surface.
3. Consider the Axillary vein in preference for the subclavian vein
4. Use micro-puncture techniques
5. Avoid using a scalpel if possible
6. Avoid catheters being inserted all the way to the hub
7. Use impregnated dressings when possible
8. Use sutureless securing techniques
9. Secure the dressing on a flat surface (refer rule 2)
10. Ensure optimal positioning of the catheter tip by utilising ultrasound or intracavitary ECG
The assessment of right ventricular (RV) function remains one of the
most challenging and technically difficult tasks in echocardiography.
There are many anatomic and functional peculiarities that distinguish
the RV from the left ventricle, which pose significant challenges to the
conventional echocardiographic assessment of RV function and preclude the extrapolation of the knowledge and evidence accumulated
for the left side to the RV.
In the last years, RV strain imaging emerged as a superior metric of
RV systolic performance, overcoming some of the limitations of conventional echocardiographic parameters.1 RV longitudinal strain can
be measured by both tissue Doppler imaging and speckle-tracking
echocardiography (STE) techniques. The advantages of using the
speckle-tracking over the Doppler tissue imaging technique rely on
the independency of the measurements from the angle of insonation
and better reproducibility. Moreover, RV longitudinal strain measured using 2D STE has shown to be clinically useful in patients with
arrhythmogenic RV cardiomyopathy,2 and to have strong prognostic
value in a variety of diseases3 and also in the general population of
patients undergoing clinically indicated echocardiography.4
The following article is intended to provide guidance on how to reliably achieve accurate and reproducible measurements of RV strain.
All recommendations are in-line with the recently published joint
European Association of Cardiovascular Imaging/American Society of
Echocardiography consensus document on the same topic.
These simplified slides by Dr. Sidra Arshad present an overview of the non-respiratory functions of the respiratory tract.
Learning objectives:
1. Enlist the non-respiratory functions of the respiratory tract
2. Briefly explain how these functions are carried out
3. Discuss the significance of dead space
4. Differentiate between minute ventilation and alveolar ventilation
5. Describe the cough and sneeze reflexes
Study Resources:
1. Chapter 39, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 34, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 17, Human Physiology by Lauralee Sherwood, 9th edition
4. Non-respiratory functions of the lungs https://academic.oup.com/bjaed/article/13/3/98/278874
Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
Adv. biopharm. APPLICATION OF PHARMACOKINETICS : TARGETED DRUG DELIVERY SYSTEMSAkankshaAshtankar
MIP 201T & MPH 202T
ADVANCED BIOPHARMACEUTICS & PHARMACOKINETICS : UNIT 5
APPLICATION OF PHARMACOKINETICS : TARGETED DRUG DELIVERY SYSTEMS By - AKANKSHA ASHTANKAR
Knee anatomy and clinical tests 2024.pdfvimalpl1234
This includes all relevant anatomy and clinical tests compiled from standard textbooks, Campbell,netter etc..It is comprehensive and best suited for orthopaedicians and orthopaedic residents.
Tom Selleck Health: A Comprehensive Look at the Iconic Actor’s Wellness Journeygreendigital
Tom Selleck, an enduring figure in Hollywood. has captivated audiences for decades with his rugged charm, iconic moustache. and memorable roles in television and film. From his breakout role as Thomas Magnum in Magnum P.I. to his current portrayal of Frank Reagan in Blue Bloods. Selleck's career has spanned over 50 years. But beyond his professional achievements. fans have often been curious about Tom Selleck Health. especially as he has aged in the public eye.
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Introduction
Many have been interested in Tom Selleck health. not only because of his enduring presence on screen but also because of the challenges. and lifestyle choices he has faced and made over the years. This article delves into the various aspects of Tom Selleck health. exploring his fitness regimen, diet, mental health. and the challenges he has encountered as he ages. We'll look at how he maintains his well-being. the health issues he has faced, and his approach to ageing .
Early Life and Career
Childhood and Athletic Beginnings
Tom Selleck was born on January 29, 1945, in Detroit, Michigan, and grew up in Sherman Oaks, California. From an early age, he was involved in sports, particularly basketball. which played a significant role in his physical development. His athletic pursuits continued into college. where he attended the University of Southern California (USC) on a basketball scholarship. This early involvement in sports laid a strong foundation for his physical health and disciplined lifestyle.
Transition to Acting
Selleck's transition from an athlete to an actor came with its physical demands. His first significant role in "Magnum P.I." required him to perform various stunts and maintain a fit appearance. This role, which he played from 1980 to 1988. necessitated a rigorous fitness routine to meet the show's demands. setting the stage for his long-term commitment to health and wellness.
Fitness Regimen
Workout Routine
Tom Selleck health and fitness regimen has evolved. adapting to his changing roles and age. During his "Magnum, P.I." days. Selleck's workouts were intense and focused on building and maintaining muscle mass. His routine included weightlifting, cardiovascular exercises. and specific training for the stunts he performed on the show.
Selleck adjusted his fitness routine as he aged to suit his body's needs. Today, his workouts focus on maintaining flexibility, strength, and cardiovascular health. He incorporates low-impact exercises such as swimming, walking, and light weightlifting. This balanced approach helps him stay fit without putting undue strain on his joints and muscles.
Importance of Flexibility and Mobility
In recent years, Selleck has emphasized the importance of flexibility and mobility in his fitness regimen. Understanding the natural decline in muscle mass and joint flexibility with age. he includes stretching and yoga in his routine. These practices help prevent injuries, improve posture, and maintain mobilit
micro teaching on communication m.sc nursing.pdfAnurag Sharma
Microteaching is a unique model of practice teaching. It is a viable instrument for the. desired change in the teaching behavior or the behavior potential which, in specified types of real. classroom situations, tends to facilitate the achievement of specified types of objectives.
Flu Vaccine Alert in Bangalore Karnatakaaddon Scans
As flu season approaches, health officials in Bangalore, Karnataka, are urging residents to get their flu vaccinations. The seasonal flu, while common, can lead to severe health complications, particularly for vulnerable populations such as young children, the elderly, and those with underlying health conditions.
Dr. Vidisha Kumari, a leading epidemiologist in Bangalore, emphasizes the importance of getting vaccinated. "The flu vaccine is our best defense against the influenza virus. It not only protects individuals but also helps prevent the spread of the virus in our communities," he says.
This year, the flu season is expected to coincide with a potential increase in other respiratory illnesses. The Karnataka Health Department has launched an awareness campaign highlighting the significance of flu vaccinations. They have set up multiple vaccination centers across Bangalore, making it convenient for residents to receive their shots.
To encourage widespread vaccination, the government is also collaborating with local schools, workplaces, and community centers to facilitate vaccination drives. Special attention is being given to ensuring that the vaccine is accessible to all, including marginalized communities who may have limited access to healthcare.
Residents are reminded that the flu vaccine is safe and effective. Common side effects are mild and may include soreness at the injection site, mild fever, or muscle aches. These side effects are generally short-lived and far less severe than the flu itself.
Healthcare providers are also stressing the importance of continuing COVID-19 precautions. Wearing masks, practicing good hand hygiene, and maintaining social distancing are still crucial, especially in crowded places.
Protect yourself and your loved ones by getting vaccinated. Together, we can help keep Bangalore healthy and safe this flu season. For more information on vaccination centers and schedules, residents can visit the Karnataka Health Department’s official website or follow their social media pages.
Stay informed, stay safe, and get your flu shot today!
Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
Ocular injury ppt Upendra pal optometrist upums saifai etawah
Ivus evar
1. Dr. Michelangelo Ferri – Dr. Andrea Viazzo
S.C. Chirurgia Vascolare - Ospedale Mauriziano Umberto I
Torino
IVUS for Abdominal Aortic
Aneurysm
I part
Bologna, 10 novembre 2016
2. IVUS in EVAR procedure
2
Digital imaging catheter (Visions PV
.035) ensures accuracy of critical size
measurements of larger vessels up to
60 mm
.038” and .035” guide wire compatible
90cm Over The Wire catheter design
(for outstanding trackability and
pushability)
3. Why IVUS in EVAR?
Rationale
•Minimise renal load with contrast media
•Minimise X-ray exposure time
•During procedure
– Accurate measurement of the diameter and
the lenght of the neck
– Optimizing deployment
– Accurate evaluation iliac accesses
4. …this may change with routine use of intravascular ultrasound (IVUS)providing real time read out of
luminal vascular dimensions, in combination with identification of vessel branches, and simultaneous
possibility of vessel wall analyses.
…the amount of radiopaque contrast medium injected per patient was zero in 47/80 patients (59%) of the
entire series
IVUS is a reliable tool for target site identification, landing zone measurement, neck quality analysis,
perprocedural quality assessment, and trouble shooting during endovascular aortic aneurysm repair. In most
cases, perprocedural angiography is not necessary for endovascular aneurysm repair.
5. • Using IVUS technology allows one to identify the renal vein as our landmark, and subsequently
identification of the diameter and length of the neck…
• Presence of thrombus at the neck of the aneurysm may be a relative contraindication for deployment
of an endograft, and this can easily be detected with the help of an IVUS.
• Intravascular ultrasound is also helpful for determination of apposition of the stent graft to the aortic
wall
• A significant advantage of IVUS in comparison with the angiogram is that it may be used instead of
the angiogram to save contrast on a patient that has renal insufficiency
6. Conclusion:
IVUS can reduce radiation and contrast exposure from both
preoperative CT scans and intraoperative angiography.
IVUS allows for precise device sizing and identification of critical
vessel origins.
As more users become familiar with interpretation of the IVUS
imaging, many procedures can be performed with limited or no use
of iodinated contrast agents.
IVUS is invaluable in identifying true lumen access and defining
entry sites in dissection pathology. It allows for precise placement
of endovascular devices and limits the extent of aortic coverage.
Minimising contrast medium and X-ray exposure
Semin Vasc Surg. 2009 Sep;22(3):172-80
7. Eur J Vasc Endovasc Surg. 2010 Nov;40(5):559-63
Minimising contrast medium and X-ray exposure
112 patients divided in 2 groups:
• non IVUS (n=79)
• IVUS (n=33)
Subsets of IVUS
(17 pazients with renal dysfunction or suspected allergy to intravascular
arterial contrast agents):
IACA 67 ± 34 ml
Patients non-IVUS group:
IACA 123 ± 50 ml
Conclusion:
IVUS is a powerful auxiliary method in EVAR for reducing the volume of contrast agent
and reducing radiation exposure to patients and operators. The authors recommend the
routine use of IVUS during EVAR procedures, but they stress that IACAs are usually a
necessary component of this technique.
8. Abdominal Aorta
When imaging at the level of the renal vein,
rotate the image so that the renal vein is at 12
o’clock
To rotate: when LIVE, click ADJUST IMAGE
and use the REVOLVE key
This is because the renal vein naturally runs
anterior to the aorta
9. EVAR procedure recommendations (1)
Obtain bilateral access to the femoral arteries
Insert 5F sheath
Insert glide wire and marker pigtail catheter on the side designated to deliver the main
body of the graft
Perform angiogram
At this point you will use the markers on the pigtail to get a length measurement for the
main body of the graft (lowest renal artery to hypogastric)
Remove pigtail catheter and insert 9F or 11F sheaths to both sides
10. Insert IVUS catheter
On the side where the main body of the graft will be inserted
Advance IVUS catheter to locate the hypogastric take off
Mark the take off on the monitor
Continue to advance the catheter to locate the renal vein and renal arteries
Mark the level of the lowest renal on the monitor
Advance catheter to the level of the celiac and record a pullback
Go back through the pullback and make your measurements
EVAR procedure recommendations (2)
11. 11
Identification of anatomic references
With .035” or .038” guide wire is possible
identify:
Celiac trunk
Left renal vein
Renal Arteries
Aneurysm
Aortic bifurcation and iliac vessels
Hypogastric arteries
Renal vein
Renal artery
12. Examples of length measurements with IVUS
12
Celiac
SMA
Aneurysm
LFT. Renal Artery
Renal Vein
Hypogastrics
Common illiacs
Length
Length
Length Measurements
IVUS to ensure 25mm distal support.
Length measurements:
1. Infrarenal to base of proximal neck
2. Infrarenal to bifurcation of aorta (illiacs)
3. Base of neck to bifurcation of aorta
(illiacs)
4. Illiacs to Hypogastrics
24. IVUSandangiogrampostEVAR
1° caso 3° caso2° caso
IVUS is utilized to choose
a graft appropriately
and to confirm the correct
deployment under renal
arteries
25. EVAR: Endo-Vascular Aneurysm Repair
Infrarenalneck
diameter
Renalvein
1° caso 3° caso2° caso
Leftrenalartery
Rightrenal
artery
Guidewire
Calcific plaque
26. 1° caso 3° caso2° caso
Renalvein
Measurement ofneckdiameter
27. 1° caso 3° caso2° caso
IVUS catheter:EVARguidedby
intravascularultrasound
Rightrenalartery