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The document discusses acute respiratory tract infections (ARIs), which affect the respiratory tract and include conditions like the common cold and pneumonia. ARIs are classified as upper respiratory tract infections (URTIs) or lower respiratory tract infections (LRTIs), with LRTIs causing around 3.1 million deaths annually. Risk factors for ARIs include age, lack of breastfeeding, smoking, and air pollution. Prevention methods include handwashing, vaccinations, and controlling risk factors.

31-Mar-16 1Acute Respiratory Tract Infection
Microbiology
Pediatrics

Acute Respiratory tract infection
Dr Jayaramachandran S
Assistant Professor
Dept. of Community Medicine
MGMC & RI

Introduction
31-Mar-16 Acute Respiratory Tract Infection 3

Introduction
31-Mar-16 Acute Respiratory Tract Infection 4

31-Mar-16 Acute Respiratory Tract Infection 5
LRTI : 3.1 millions deaths

31-Mar-16 Acute Respiratory Tract Infection 6

Definition of ARI
31-Mar-16 Acute Respiratory Tract Infection 7

Classification of ARI
31-Mar-16 8Acute Respiratory Tract Infection

31-Mar-16 Acute Respiratory Tract Infection 9

31-Mar-16 Acute Respiratory Tract Infection 10

Mode of Spread
31-Mar-16 Acute Respiratory Tract Infection 11

Risk factors
31-Mar-16 Acute Respiratory Tract Infection 12

Risk factor
31-Mar-16 Acute Respiratory Tract Infection 13

Risk factor
31-Mar-16 Acute Respiratory Tract Infection 14

Risk factor
31-Mar-16 Acute Respiratory Tract Infection 15

Risk factor
31-Mar-16 Acute Respiratory Tract Infection 16

Risk factors
31-Mar-16 Acute Respiratory Tract Infection 17

Risk factor
31-Mar-16 Acute Respiratory Tract Infection 18

Risk factor
31-Mar-16 Acute Respiratory Tract Infection 19

Risk factor
31-Mar-16 Acute Respiratory Tract Infection 20

Risk factor
31-Mar-16 Acute Respiratory Tract Infection 21

Risk factors
31-Mar-16 Acute Respiratory Tract Infection 22

Risk factors
31-Mar-16 Acute Respiratory Tract Infection 23

Risk factors
31-Mar-16 Acute Respiratory Tract Infection 24

Risk factors
31-Mar-16 Acute Respiratory Tract Infection 25

Prevention & Control
31-Mar-16 Acute Respiratory Tract Infection 26

Prevention & Control
31-Mar-16 Acute Respiratory Tract Infection 27

Prevention & Control
31-Mar-16 Acute Respiratory Tract Infection 28

Prevention & Control
• Vaccines
31-Mar-16 Acute Respiratory Tract Infection 29

Prevention & Control
• Vaccines
31-Mar-16 Acute Respiratory Tract Infection 30

Prevention & Control
• Vaccines
31-Mar-16 Acute Respiratory Tract Infection 31

Prevention & Control
• Vaccines
31-Mar-16 Acute Respiratory Tract Infection 32

Prevention & Control
• Vaccines
31-Mar-16 Acute Respiratory Tract Infection 33

Thank you…
31-Mar-16 Acute Respiratory Tract Infection 34

Meningococcal disease is a severe illness with high case fatality (5-10%) and frequent sequelae. Meningococcal meningitis is a major cause of morbidity and mortality in the meningitis belt. Meningococcal disease is a major public health challenge in countries of sub-Saharan Africa lying in the meningitis belt. Human infections caused by meningococcal (Neisseria meningitidis) remain a serious health problem, infecting 500,000 to 1.2 million people and killing between 50,000 and 135,000 per year worldwide. The causative agent, Neisseria meningitidis normally lives in a commensal relationship with humans, colonizing the nasopharynx, and is transmitted between healthy persons by close contact. The most common symptoms are a stiff neck, high fever, sensitivity to light, confusion, headaches and vomiting. Low meningitis thresholds improve timely detection of epidemics. The diagnosis of meningococcal meningitis is confirmed by cerebrospinal fluid pleocytosis, Gram stain, polymerase chain reaction, culture of cerebrospinal fluid. Meningococcal disease can be treated with a number of effective antibiotics. It is important that treatment be started as soon as possible. If meningococcal disease is suspected, antibiotics are given right away. Antibiotics effective for this purpose include rifampicin, ciprofloxacin, ceftriaxone or azithromycin. Currently available meningococcal vaccines include polysaccharide vaccines against serogroups A, C, W135 & Y and newer protein polysaccharide conjugate vaccines against serogroup C. This review covers key aspects of the pathogenesis and management of meningococcal disease, as well as the very recent developments in disease epidemiology, outbreaks, and the evolution of meningococcal immunizations.

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Common antibiotics prescribed for acute respiratory tract infected children i...

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Background: Acute respiratory infection is a common disease in children. Most cases were due to upper respiratory tract infection. Early intervention and prompt treatment of acute respiratory infections are the easiest ways to prevent complications. Objective of the study: to determine the indications, frequency, and types of antibiotics used in hospitalized paediatric patients Messellata General Hospital , Messellata, Libya and to evaluate whether the prescribed antibiotics were based on the isolation of organism and their sensitivity. Study Design: Descriptive observational hospital based study. Results and discussion: A total of 200 child patients were included over 6 months of study period, in whom antibiotics were prescribed at the time of admission. The majority were between < 2 and 8 years of age. Fever was the commonest symptom. Out of 200 encounters for patients with various acute respiratory infections, acute pharyngotonsillits were (62.5%), followed by acute laringitis (26.5%). Acute pneumonia represented by (11%) of the total acute respiratory infection cases. Penicillins were the most commonly prescribed antibiotics for acute pharyngotonsillitis among children patients (40.8% of prescriptions), followed by cephalosporins (36.0%) and aminoglycosides (23.2%). A high percentage (59.1%) of children patients diagnosed with acute pneumonia was treated with cephalosporins, whereas (27.3%) of children patients with acute pneumonia were treated with penicillins. However, only (13.6%) of children patients with acute pneumonia often treated with aminoglycosides antibiotics. In case of acute laryngitis, the antibiotic prescription rates were as follow: Penicillins (58.5%), Cephalosporis (30.2%) and aminoglycosides (11.3%).

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Tuberculosis (TB) is among the 10 most common worldwide causes of mortality. In Pakistan, estimated 510,000 tuberculosis patients had been diagnosed with an occurrence of 276/100,000. As per most recent global TB report 2018, Pakistan is amongst the 30 countries high TB with drug-resistant Mycobacterium tuberculosis particularly MDR (multi-drug resistant strains). A retrospective study had been designed using DR-TB patients’ records from January 2013 to the December 2017 year from a public sector hospital in Karachi. Overall 315 drug-resistant tuberculosis patient’s data had been incorporated in the study. All data had been analyzed using SPSS version 16 software. Chi-square test had been used to analyze the data with CI (confidence interval) 95% and level of significance 5%. The study result showed that 64.1% MDR patients, 27.9% MTB rifampicin resistance, 4.8% mono-drug resistant , XDR(1.6%), 1% poly-drug resistant and only 0.6% are MDR suspects showing no association of DR-TB with gender (p-value 0.787), age group (p-value 0.757), treatment outcomes (p-value 0.549), year of registration( p-value 0.206), first line treatment history(p-value 0.643) with a 95% confidence interval. The drug resistance TB cases have been periodically rising every year. Early identification is required to reduce the percent mortality and inhibit the disease transmission.

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Travel-related infectious diseases on the rise International travel has an important role in the transmission of emerging and re-emerging infectious diseases across geographical areas. Since 1980, the world has been threatened by different waves of emerging disease epidemics. In the twenty-first century, these diseases have become an increasing global concern because of their health and economic impacts in both developed and resource-constrained countries. It is difficult to stop the occurrence of new pathogens in the future due to the interconnection among humans, animals, and the environment. As many as 43%–79% of travelers to low- and middle-income countries become ill with a travel-related health problem. Although most of these illnesses are mild, some travelers become sick enough to seek care from a health care provider.

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Stewardship is the act of taking good care of something. Antimicrobial stewardship is a coordinated program that promotes the appropriate use of antimicrobials (including antibiotics), improves patient outcomes, reduces microbial resistance, and decreases the spread of infections caused by multidrug-resistant organisms. WHO launched the Global Antimicrobial Resistance and Use Surveillance System (GLASS) in 2015 to fill knowledge gaps and inform strategies at all levels. ACCORDING TO apic.org, Antimicrobial stewardship is a coordinated program that promotes the appropriate use of antimicrobials (including antibiotics), improves patient outcomes, reduces microbial resistance, and decreases the spread of infections caused by multidrug-resistant organisms. ACCORDING TO pewtrusts.org, Antibiotic stewardship refers to efforts in doctors’ offices, hospitals, long term care facilities, and other health care settings to ensure that antibiotics are used only when necessary and appropriate According to WHO, Antimicrobial stewardship is a systematic approach to educate and support health care professionals to follow evidence-based guidelines for prescribing and administering antimicrobials In 1996, John McGowan and Dale Gerding first applied the term antimicrobial stewardship, where they suggested a causal association between antimicrobial agent use and resistance. They also focused on the urgency of large-scale controlled trials of antimicrobial-use regulation employing sophisticated epidemiologic methods, molecular typing, and precise resistance mechanism analysis. Antimicrobial Stewardship(AMS) refers to the optimal selection, dosing, and duration of antimicrobial treatment resulting in the best clinical outcome with minimal side effects to the patients and minimal impact on subsequent resistance. According to the 2019 report, in the US, more than 2.8 million antibiotic-resistant infections occur each year, and more than 35000 people die. In addition to this, it also mentioned that 223,900 cases of Clostridoides difficile occurred in 2017, of which 12800 people died. The report did not include viruses or parasites VISION Being proactive Supporting optimal animal and human health Exploring ways to reduce overall use of antimicrobials Using the drugs that prevent and treat disease by killing microscopic organisms in a responsible way GOAL to prevent the generation and spread of antimicrobial resistance (AMR). Doing so will preserve the effectiveness of these drugs in animals and humans for years to come. being to preserve human and animal health and the effectiveness of antimicrobial medications. to implement a multidisciplinary approach in assembling a stewardship team to include an infectious disease physician, a clinical pharmacist with infectious diseases training, infection preventionist, and a close collaboration with the staff in the clinical microbiology laboratory to prevent antimicrobial overuse, misuse and abuse. to minimize the developme

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Defecation Normal defecation begins with movement in the left colon, moving stool toward the anus. When stool reaches the rectum, the distention causes relaxation of the internal sphincter and an awareness of the need to defecate. At the time of defecation, the external sphincter relaxes, and abdominal muscles contract, increasing intrarectal pressure and forcing the stool out The Valsalva maneuver exerts pressure to expel faeces through a voluntary contraction of the abdominal muscles while maintaining forced expiration against a closed airway. Patients with cardiovascular disease, glaucoma, increased intracranial pressure, or a new surgical wound are at greater risk for cardiac dysrhythmias and elevated blood pressure with the Valsalva maneuver and need to avoid straining to pass the stool. Normal defecation is painless, resulting in passage of soft, formed stool CONSTIPATION Constipation is a symptom, not a disease. Improper diet, reduced fluid intake, lack of exercise, and certain medications can cause constipation. For example, patients receiving opiates for pain after surgery often require a stool softener or laxative to prevent constipation. The signs of constipation include infrequent bowel movements (less than every 3 days), difficulty passing stools, excessive straining, inability to defecate at will, and hard feaces IMPACTION Fecal impaction results from unrelieved constipation. It is a collection of hardened feces wedged in the rectum that a person cannot expel. In cases of severe impaction the mass extends up into the sigmoid colon. DIARRHEA Diarrhea is an increase in the number of stools and the passage of liquid, unformed feces. It is associated with disorders affecting digestion, absorption, and secretion in the GI tract. Intestinal contents pass through the small and large intestine too quickly to allow for the usual absorption of fluid and nutrients. Irritation within the colon results in increased mucus secretion. As a result, feces become watery, and the patient is unable to control the urge to defecate. Normally an anal bag is safe and effective in long-term treatment of patients with fecal incontinence at home, in hospice, or in the hospital. Fecal incontinence is expensive and a potentially dangerous condition in terms of contamination and risk of skin ulceration HEMORRHOIDS Hemorrhoids are dilated, engorged veins in the lining of the rectum. They are either external or internal. FLATULENCE As gas accumulates in the lumen of the intestines, the bowel wall stretches and distends (flatulence). It is a common cause of abdominal fullness, pain, and cramping. Normally intestinal gas escapes through the mouth (belching) or the anus (passing of flatus) FECAL INCONTINENCE Fecal incontinence is the inability to control passage of feces and gas from the anus. Incontinence harms a patient’s body image PREPARATION AND GIVING OF LAXATIVESACCORDING TO POTTER AND PERRY, An enema is the instillation of a solution into the rectum and sig

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Itp ari

1. 31-Mar-16 1Acute Respiratory Tract Infection Microbiology Pediatrics

2. Acute Respiratory tract infection Dr Jayaramachandran S Assistant Professor Dept. of Community Medicine MGMC & RI

3. Introduction 31-Mar-16 Acute Respiratory Tract Infection 3

4. Introduction 31-Mar-16 Acute Respiratory Tract Infection 4

5. 31-Mar-16 Acute Respiratory Tract Infection 5 LRTI : 3.1 millions deaths

6. 31-Mar-16 Acute Respiratory Tract Infection 6

7. Definition of ARI 31-Mar-16 Acute Respiratory Tract Infection 7

8. Classification of ARI 31-Mar-16 8Acute Respiratory Tract Infection

9. 31-Mar-16 Acute Respiratory Tract Infection 9

10. 31-Mar-16 Acute Respiratory Tract Infection 10

11. Mode of Spread 31-Mar-16 Acute Respiratory Tract Infection 11

12. Risk factors 31-Mar-16 Acute Respiratory Tract Infection 12

13. Risk factor 31-Mar-16 Acute Respiratory Tract Infection 13

14. Risk factor 31-Mar-16 Acute Respiratory Tract Infection 14

15. Risk factor 31-Mar-16 Acute Respiratory Tract Infection 15

16. Risk factor 31-Mar-16 Acute Respiratory Tract Infection 16

17. Risk factors 31-Mar-16 Acute Respiratory Tract Infection 17

18. Risk factor 31-Mar-16 Acute Respiratory Tract Infection 18

19. Risk factor 31-Mar-16 Acute Respiratory Tract Infection 19

20. Risk factor 31-Mar-16 Acute Respiratory Tract Infection 20

21. Risk factor 31-Mar-16 Acute Respiratory Tract Infection 21

22. Risk factors 31-Mar-16 Acute Respiratory Tract Infection 22

23. Risk factors 31-Mar-16 Acute Respiratory Tract Infection 23

24. Risk factors 31-Mar-16 Acute Respiratory Tract Infection 24

25. Risk factors 31-Mar-16 Acute Respiratory Tract Infection 25

26. Prevention & Control 31-Mar-16 Acute Respiratory Tract Infection 26

27. Prevention & Control 31-Mar-16 Acute Respiratory Tract Infection 27

28. Prevention & Control 31-Mar-16 Acute Respiratory Tract Infection 28

29. Prevention & Control • Vaccines 31-Mar-16 Acute Respiratory Tract Infection 29

30. Prevention & Control • Vaccines 31-Mar-16 Acute Respiratory Tract Infection 30

31. Prevention & Control • Vaccines 31-Mar-16 Acute Respiratory Tract Infection 31

32. Prevention & Control • Vaccines 31-Mar-16 Acute Respiratory Tract Infection 32

33. Prevention & Control • Vaccines 31-Mar-16 Acute Respiratory Tract Infection 33

34. Thank you… 31-Mar-16 Acute Respiratory Tract Infection 34

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