SlideShare a Scribd company logo
Iron deficiency anemia
Assistant prof .Radfan Saleh
Blood Smear Interpretation Assistant prof .Radfan Saleh
Normal blood picture Assistant prof .Radfan Saleh
Iron stain Assistant prof .Radfan Saleh
Blood film, high concentration
Assistant prof .Radfan Saleh
Blood film, low concentration
Assistant prof .Radfan Saleh
Iron deficiency is defined as a
decreased total iron body content.
Iron is vital for all living organisms
because it is essential for multiple
metabolic processes, including
oxygen transport and DNA
synthesis. Assistant prof .Radfan Saleh
Iron balance is achieved largely by
regulation of iron absorption in the
proximal small intestine.
Factors that enhance iron absorption
. Facilitators: ascorbate, citrate, amino
acids, iron deficiency
Assistant prof .Radfan Saleh
Factors that prevent iron absorption.
Inhibitors: , tannins, iron overload,
antacids
Assistant prof .Radfan Saleh
Causes of iron deficiency :-
chronic blood loss
increased iron requirement
iron malabsorption
inadequate dietary intake
1- chronic blood loss:- the most common
causes of iron deficiency in adult are :-
- Occult bleeding from the gastrointestinal
tract.
- Blood loss caused by menstruation or
pregnancy and including birth.
A) gastrointestinal bleeding: occult blood loss from the
gastrointestinal tract can be chronic without displaying
any symptoms and may go undetected until the
patient presents with symptoms of anemia this is may
be due to :- peptic ulcer, hook worm infection,
malignancies of stomach or colon.
B) uterine bleeding:- menstrual bleeding is the most
common cause of iron deficiency in woman . The
average amount of blood lost during each menstrual
cycle is about 45 ml which represents about 25mg
of iron lost each month.
C) other sources of bleeding:- this is may present
with chronic blood loss that result from hematuria or
hemoglobinuria.
2- increases in the physiologic
requirement for iron :-
This is due to increases in the requirements for
iron that exceed the amounts of iron normally
available in the diet .
infancy:- in the infant iron deficiency usually result
from an unsupplemented diet of milk that is not
capably of providing enough iron for erythropoiesis.
Adolescence:- iron deficiency is result from the
increased demands during period of increased
growth.
Pregnancy and lactation:- although menstruation ceases
during pregnancy, there is an increased demand for iron
because of fetal growth and an increased maternal red cell
mass during pregnancy
3- iron malabsorption :-
Iron deficiency may be result from two absorption
deficiency :-
A) malabsorption syndromes this due to damage in
the iron-absorbing mucosal cells of the duodenum.
B) subtotal gastrectomy:-gastric acid may not be
available for converting insoluble dietary ferric iron to
the soluble ferrous form that can be absorbed and
transport rapidly through the duodenum.
4- inadequate iron intake .
Source of iron:-
rich source (liver, heart, kidney)
Good source (leafy vegetable, fish, fruit )
Schistosomes & Eggs
Assistant prof .Radfan Saleh
iron deficiency anemia
Assistant prof .Radfan Saleh
iron deficiency anemia
Assistant prof .Radfan Saleh
Distinct microcytosis (compare with size of the
lymphocyte). Some of erythrocytes are hypochromic. A
few pencil shaped cells are seen
Assistant prof .Radfan Saleh
The arrow shows elongated pencil - like cell
Assistant prof .Radfan Saleh
The arrow shows elongated pencil - like cell
Assistant prof .Radfan Saleh
severe iron deficiency anemia
Assistant prof .Radfan Saleh
Iron stain
Assistant prof .Radfan Saleh
•
marrow particle stained for detection of free iron
shows no trace of the element
. Assistant prof .Radfan Saleh
Iron stain, depleted stores
Assistant prof .Radfan Saleh
Iron stain, depleted stores
Assistant prof .Radfan Saleh
Iron deficient Dual population treated
Assistant prof .Radfan Saleh
Diagnosis
History and clinical examination of the patient,
specially dietary history
Peripheral blood picture, hypochromic microcytic
anemia
Measurement of
Serum iron
Serum ferritin
Normal blood levels are 30-300 ng/mL for males and 15-
200 ng/mL for females
Stainable iron in bone marrow
Assistant prof .Radfan Saleh
Serum Iron (SI)
•
Men: 65 to 176 µg/ dL
•
Women: 50 to 170 µg/ dL
•
Newborns: 100 to 250 µg/ dL
•
Children: 50 to 120 µg/ dL
•
:
µg/ dL
TIBC:240-450
•
Transferrin saturation: 20-50%
Assistant prof .Radfan Saleh
CBC, iron deficiency anemia. Microcytosis is indicated by the low MCV.
Hypochromia correlates here with the low MCH.
Assistant prof .Radfan Saleh
Clinical features
anemia
The most common symptoms of
anemia are pallor, fatigue and
dyspnea
Assistant prof .Radfan Saleh
koilonychia
Assistant prof .Radfan Saleh
koilonychia
Assistant prof .Radfan Saleh
koilonychia
Assistant prof .Radfan Saleh
Angular cheilitis
Assistant prof .Radfan Saleh
Angular cheilitis
Assistant prof .Radfan Saleh
Diagnosis of iron deficiency anemia:-
1- peripheral blood findings:-
hemoglobin :- 5 – 10 g/dl.
haematocrit :- low MCV
low MCH
2- peripheral blood smears:-
microcytic, hypochromic red cells.
poikilocytosis, which are abnormal shaped
RBCs
Pencil shape are feature in iron deficiency
anemia
Causes of Anemia of Chronic
Disease
Any disease condition that is associated with
inflammation, and that lasts more than 1 or 2
months, can cause anemia of chronic disease.
In some cases, the inflammation is obvious (chronic
infections or rheumatic disorders, for example); in
other cases, the inflammation is less obvious
(malignancies).
Chronic illnesses that are not associated with
inflammation (for example, hypertension or
diabetes mellitus) are not usually associated with
the anemia of chronic disease.
Laboratory Diagnosis
1- The anemia due to chronic disease is usually mild or moderate:
blood hemoglobin levels ≥8 to 10 g/dL.
However, the anemia may be more severe
in chronic illnesses with marked inflammation. The anemia is
usually normocytic and normochromic but can be microcytic in
severe cases.
2- MCV is usually only mildly decreased (≥70 fL).
3- The reticulocyte count is low.
4- erythrocyte sedimentation rate are usually increased.
iron deficiency anemia for laboratory students.ppt
iron deficiency anemia for laboratory students.ppt

More Related Content

Similar to iron deficiency anemia for laboratory students.ppt

Anemia Panel - New.pptx
Anemia Panel - New.pptxAnemia Panel - New.pptx
Anemia Panel - New.pptx
Drneelimayadav2
 
Iron deficiency anemia
Iron deficiency anemiaIron deficiency anemia
Iron deficiency anemia
Snehil Agrawal
 
Approach to a case of iron defciency anaemia
Approach to a case of iron defciency anaemiaApproach to a case of iron defciency anaemia
Approach to a case of iron defciency anaemia
Sachin Adukia
 
Microcytic hypochromic anemia
Microcytic hypochromic anemia Microcytic hypochromic anemia
Microcytic hypochromic anemia
Ahmed Abdelhakeem
 
Iron deficiency anemia.
Iron deficiency anemia.Iron deficiency anemia.
Iron deficiency anemia.
Ameenah
 
Fluorosis Anemia Iodine deficincey disorder_relation
Fluorosis Anemia Iodine deficincey disorder_relationFluorosis Anemia Iodine deficincey disorder_relation
Fluorosis Anemia Iodine deficincey disorder_relation
drdduttaM
 
Iron deficiency anemia
Iron deficiency anemiaIron deficiency anemia
Iron deficiency anemia
Habibah Chaudhary
 
Module 4: Nutrient Deficiencies: Iron and Vitamin D
Module 4: Nutrient Deficiencies: Iron and Vitamin DModule 4: Nutrient Deficiencies: Iron and Vitamin D
Module 4: Nutrient Deficiencies: Iron and Vitamin D
Nutrition Resource Centre
 
irondeficiencyanemiafinal-111212143737-phpapp01 (1).pptx
irondeficiencyanemiafinal-111212143737-phpapp01 (1).pptxirondeficiencyanemiafinal-111212143737-phpapp01 (1).pptx
irondeficiencyanemiafinal-111212143737-phpapp01 (1).pptx
KalyanAcharya10
 
Sankhla Akshit PPT.pptx
Sankhla Akshit PPT.pptxSankhla Akshit PPT.pptx
Sankhla Akshit PPT.pptx
KalyanAcharya10
 
IRON DEFICIENCY.pdf
IRON DEFICIENCY.pdfIRON DEFICIENCY.pdf
IRON DEFICIENCY.pdf
58NitinSinha
 
Anemia (iron deficiency anemia)
Anemia (iron deficiency anemia)Anemia (iron deficiency anemia)
Anemia (iron deficiency anemia)
JinalChaudhari5
 
Anaemia.pptx
Anaemia.pptxAnaemia.pptx
Anaemia.pptx
Imtiyaz60
 
Iron deficiency anemia
Iron deficiency anemiaIron deficiency anemia
Iron deficiency anemia
The Medical Post
 
Bems Rabia presentation
Bems Rabia presentationBems Rabia presentation
Bems Rabia presentation
Aamir Sharif
 
Rabia presentation
Rabia presentationRabia presentation
Rabia presentation
Aamir Sharif
 
HS-_Iron_Deficiency_Anemia.pdf
HS-_Iron_Deficiency_Anemia.pdfHS-_Iron_Deficiency_Anemia.pdf
HS-_Iron_Deficiency_Anemia.pdf
SanjayaManiDixit
 
2 microcytic anemia i-iron deficiency.ppt
2 microcytic anemia i-iron deficiency.ppt2 microcytic anemia i-iron deficiency.ppt
2 microcytic anemia i-iron deficiency.ppt
AbdulKaderSouid
 
Iron deficiency anaemia (for v year mbbs)
Iron deficiency anaemia (for v year mbbs)Iron deficiency anaemia (for v year mbbs)
Iron deficiency anaemia (for v year mbbs)
mona aziz
 
Anemia.pptx
Anemia.pptxAnemia.pptx
Anemia.pptx
ssuser75fd45
 

Similar to iron deficiency anemia for laboratory students.ppt (20)

Anemia Panel - New.pptx
Anemia Panel - New.pptxAnemia Panel - New.pptx
Anemia Panel - New.pptx
 
Iron deficiency anemia
Iron deficiency anemiaIron deficiency anemia
Iron deficiency anemia
 
Approach to a case of iron defciency anaemia
Approach to a case of iron defciency anaemiaApproach to a case of iron defciency anaemia
Approach to a case of iron defciency anaemia
 
Microcytic hypochromic anemia
Microcytic hypochromic anemia Microcytic hypochromic anemia
Microcytic hypochromic anemia
 
Iron deficiency anemia.
Iron deficiency anemia.Iron deficiency anemia.
Iron deficiency anemia.
 
Fluorosis Anemia Iodine deficincey disorder_relation
Fluorosis Anemia Iodine deficincey disorder_relationFluorosis Anemia Iodine deficincey disorder_relation
Fluorosis Anemia Iodine deficincey disorder_relation
 
Iron deficiency anemia
Iron deficiency anemiaIron deficiency anemia
Iron deficiency anemia
 
Module 4: Nutrient Deficiencies: Iron and Vitamin D
Module 4: Nutrient Deficiencies: Iron and Vitamin DModule 4: Nutrient Deficiencies: Iron and Vitamin D
Module 4: Nutrient Deficiencies: Iron and Vitamin D
 
irondeficiencyanemiafinal-111212143737-phpapp01 (1).pptx
irondeficiencyanemiafinal-111212143737-phpapp01 (1).pptxirondeficiencyanemiafinal-111212143737-phpapp01 (1).pptx
irondeficiencyanemiafinal-111212143737-phpapp01 (1).pptx
 
Sankhla Akshit PPT.pptx
Sankhla Akshit PPT.pptxSankhla Akshit PPT.pptx
Sankhla Akshit PPT.pptx
 
IRON DEFICIENCY.pdf
IRON DEFICIENCY.pdfIRON DEFICIENCY.pdf
IRON DEFICIENCY.pdf
 
Anemia (iron deficiency anemia)
Anemia (iron deficiency anemia)Anemia (iron deficiency anemia)
Anemia (iron deficiency anemia)
 
Anaemia.pptx
Anaemia.pptxAnaemia.pptx
Anaemia.pptx
 
Iron deficiency anemia
Iron deficiency anemiaIron deficiency anemia
Iron deficiency anemia
 
Bems Rabia presentation
Bems Rabia presentationBems Rabia presentation
Bems Rabia presentation
 
Rabia presentation
Rabia presentationRabia presentation
Rabia presentation
 
HS-_Iron_Deficiency_Anemia.pdf
HS-_Iron_Deficiency_Anemia.pdfHS-_Iron_Deficiency_Anemia.pdf
HS-_Iron_Deficiency_Anemia.pdf
 
2 microcytic anemia i-iron deficiency.ppt
2 microcytic anemia i-iron deficiency.ppt2 microcytic anemia i-iron deficiency.ppt
2 microcytic anemia i-iron deficiency.ppt
 
Iron deficiency anaemia (for v year mbbs)
Iron deficiency anaemia (for v year mbbs)Iron deficiency anaemia (for v year mbbs)
Iron deficiency anaemia (for v year mbbs)
 
Anemia.pptx
Anemia.pptxAnemia.pptx
Anemia.pptx
 

More from ssuser9976be

Tolerence and autoimmun diseases for laboratorystudents.pptx
Tolerence and autoimmun diseases for laboratorystudents.pptxTolerence and autoimmun diseases for laboratorystudents.pptx
Tolerence and autoimmun diseases for laboratorystudents.pptx
ssuser9976be
 
nephritis lecture for laboratory students -1.pptx
nephritis lecture  for  laboratory students -1.pptxnephritis lecture  for  laboratory students -1.pptx
nephritis lecture for laboratory students -1.pptx
ssuser9976be
 
histology for laboratory students 8.pptx
histology  for  laboratory  students 8.pptxhistology  for  laboratory  students 8.pptx
histology for laboratory students 8.pptx
ssuser9976be
 
5Sickle Cell Disease-hematology disease .ppt
5Sickle Cell Disease-hematology disease .ppt5Sickle Cell Disease-hematology disease .ppt
5Sickle Cell Disease-hematology disease .ppt
ssuser9976be
 
5Sickle Cell Disease-hematology disease .ppt
5Sickle Cell Disease-hematology disease  .ppt5Sickle Cell Disease-hematology disease  .ppt
5Sickle Cell Disease-hematology disease .ppt
ssuser9976be
 
2 Anaemia blood diseases for medical laboratory.ppt
2 Anaemia blood diseases for medical laboratory.ppt2 Anaemia blood diseases for medical laboratory.ppt
2 Anaemia blood diseases for medical laboratory.ppt
ssuser9976be
 
5 Ischemia Infarction & Gangrene in pathology.pptx
5 Ischemia Infarction & Gangrene in pathology.pptx5 Ischemia Infarction & Gangrene in pathology.pptx
5 Ischemia Infarction & Gangrene in pathology.pptx
ssuser9976be
 
respiratory system 54172for anatomy students.ppt
respiratory system 54172for anatomy students.pptrespiratory system 54172for anatomy students.ppt
respiratory system 54172for anatomy students.ppt
ssuser9976be
 
6 Haemoglobinopathies blood diseases.ppt
6 Haemoglobinopathies blood diseases.ppt6 Haemoglobinopathies blood diseases.ppt
6 Haemoglobinopathies blood diseases.ppt
ssuser9976be
 
5Sickle Cell Disease-blood diseases .ppt
5Sickle Cell Disease-blood diseases .ppt5Sickle Cell Disease-blood diseases .ppt
5Sickle Cell Disease-blood diseases .ppt
ssuser9976be
 
3 iron deficiency anemia blood diseases.ppt
3 iron deficiency anemia blood diseases.ppt3 iron deficiency anemia blood diseases.ppt
3 iron deficiency anemia blood diseases.ppt
ssuser9976be
 
virology level 3 taiz lecture university 1 .pptx
virology level 3 taiz lecture university 1 .pptxvirology level 3 taiz lecture university 1 .pptx
virology level 3 taiz lecture university 1 .pptx
ssuser9976be
 
General_Laboratory_S.ppt for laboratory re
General_Laboratory_S.ppt for laboratory reGeneral_Laboratory_S.ppt for laboratory re
General_Laboratory_S.ppt for laboratory re
ssuser9976be
 
house fly.ppt
house fly.ppthouse fly.ppt
house fly.ppt
ssuser9976be
 
المحاضرة الأولى بروتوزوا .pptx
المحاضرة الأولى بروتوزوا .pptxالمحاضرة الأولى بروتوزوا .pptx
المحاضرة الأولى بروتوزوا .pptx
ssuser9976be
 
Nocardia.pptx
Nocardia.pptxNocardia.pptx
Nocardia.pptx
ssuser9976be
 
نشاط بكتيريا.pptx
نشاط بكتيريا.pptxنشاط بكتيريا.pptx
نشاط بكتيريا.pptx
ssuser9976be
 
urinary system.pptx
urinary system.pptxurinary system.pptx
urinary system.pptx
ssuser9976be
 
Amoebiasis.pptx
Amoebiasis.pptxAmoebiasis.pptx
Amoebiasis.pptx
ssuser9976be
 
pcr final lecture.pptx
pcr final lecture.pptxpcr final lecture.pptx
pcr final lecture.pptx
ssuser9976be
 

More from ssuser9976be (20)

Tolerence and autoimmun diseases for laboratorystudents.pptx
Tolerence and autoimmun diseases for laboratorystudents.pptxTolerence and autoimmun diseases for laboratorystudents.pptx
Tolerence and autoimmun diseases for laboratorystudents.pptx
 
nephritis lecture for laboratory students -1.pptx
nephritis lecture  for  laboratory students -1.pptxnephritis lecture  for  laboratory students -1.pptx
nephritis lecture for laboratory students -1.pptx
 
histology for laboratory students 8.pptx
histology  for  laboratory  students 8.pptxhistology  for  laboratory  students 8.pptx
histology for laboratory students 8.pptx
 
5Sickle Cell Disease-hematology disease .ppt
5Sickle Cell Disease-hematology disease .ppt5Sickle Cell Disease-hematology disease .ppt
5Sickle Cell Disease-hematology disease .ppt
 
5Sickle Cell Disease-hematology disease .ppt
5Sickle Cell Disease-hematology disease  .ppt5Sickle Cell Disease-hematology disease  .ppt
5Sickle Cell Disease-hematology disease .ppt
 
2 Anaemia blood diseases for medical laboratory.ppt
2 Anaemia blood diseases for medical laboratory.ppt2 Anaemia blood diseases for medical laboratory.ppt
2 Anaemia blood diseases for medical laboratory.ppt
 
5 Ischemia Infarction & Gangrene in pathology.pptx
5 Ischemia Infarction & Gangrene in pathology.pptx5 Ischemia Infarction & Gangrene in pathology.pptx
5 Ischemia Infarction & Gangrene in pathology.pptx
 
respiratory system 54172for anatomy students.ppt
respiratory system 54172for anatomy students.pptrespiratory system 54172for anatomy students.ppt
respiratory system 54172for anatomy students.ppt
 
6 Haemoglobinopathies blood diseases.ppt
6 Haemoglobinopathies blood diseases.ppt6 Haemoglobinopathies blood diseases.ppt
6 Haemoglobinopathies blood diseases.ppt
 
5Sickle Cell Disease-blood diseases .ppt
5Sickle Cell Disease-blood diseases .ppt5Sickle Cell Disease-blood diseases .ppt
5Sickle Cell Disease-blood diseases .ppt
 
3 iron deficiency anemia blood diseases.ppt
3 iron deficiency anemia blood diseases.ppt3 iron deficiency anemia blood diseases.ppt
3 iron deficiency anemia blood diseases.ppt
 
virology level 3 taiz lecture university 1 .pptx
virology level 3 taiz lecture university 1 .pptxvirology level 3 taiz lecture university 1 .pptx
virology level 3 taiz lecture university 1 .pptx
 
General_Laboratory_S.ppt for laboratory re
General_Laboratory_S.ppt for laboratory reGeneral_Laboratory_S.ppt for laboratory re
General_Laboratory_S.ppt for laboratory re
 
house fly.ppt
house fly.ppthouse fly.ppt
house fly.ppt
 
المحاضرة الأولى بروتوزوا .pptx
المحاضرة الأولى بروتوزوا .pptxالمحاضرة الأولى بروتوزوا .pptx
المحاضرة الأولى بروتوزوا .pptx
 
Nocardia.pptx
Nocardia.pptxNocardia.pptx
Nocardia.pptx
 
نشاط بكتيريا.pptx
نشاط بكتيريا.pptxنشاط بكتيريا.pptx
نشاط بكتيريا.pptx
 
urinary system.pptx
urinary system.pptxurinary system.pptx
urinary system.pptx
 
Amoebiasis.pptx
Amoebiasis.pptxAmoebiasis.pptx
Amoebiasis.pptx
 
pcr final lecture.pptx
pcr final lecture.pptxpcr final lecture.pptx
pcr final lecture.pptx
 

Recently uploaded

How to Create a More Engaging and Human Online Learning Experience
How to Create a More Engaging and Human Online Learning Experience How to Create a More Engaging and Human Online Learning Experience
How to Create a More Engaging and Human Online Learning Experience
Wahiba Chair Training & Consulting
 
How to Make a Field Mandatory in Odoo 17
How to Make a Field Mandatory in Odoo 17How to Make a Field Mandatory in Odoo 17
How to Make a Field Mandatory in Odoo 17
Celine George
 
math operations ued in python and all used
math operations ued in python and all usedmath operations ued in python and all used
math operations ued in python and all used
ssuser13ffe4
 
What is Digital Literacy? A guest blog from Andy McLaughlin, University of Ab...
What is Digital Literacy? A guest blog from Andy McLaughlin, University of Ab...What is Digital Literacy? A guest blog from Andy McLaughlin, University of Ab...
What is Digital Literacy? A guest blog from Andy McLaughlin, University of Ab...
GeorgeMilliken2
 
ANATOMY AND BIOMECHANICS OF HIP JOINT.pdf
ANATOMY AND BIOMECHANICS OF HIP JOINT.pdfANATOMY AND BIOMECHANICS OF HIP JOINT.pdf
ANATOMY AND BIOMECHANICS OF HIP JOINT.pdf
Priyankaranawat4
 
The History of Stoke Newington Street Names
The History of Stoke Newington Street NamesThe History of Stoke Newington Street Names
The History of Stoke Newington Street Names
History of Stoke Newington
 
Walmart Business+ and Spark Good for Nonprofits.pdf
Walmart Business+ and Spark Good for Nonprofits.pdfWalmart Business+ and Spark Good for Nonprofits.pdf
Walmart Business+ and Spark Good for Nonprofits.pdf
TechSoup
 
ZK on Polkadot zero knowledge proofs - sub0.pptx
ZK on Polkadot zero knowledge proofs - sub0.pptxZK on Polkadot zero knowledge proofs - sub0.pptx
ZK on Polkadot zero knowledge proofs - sub0.pptx
dot55audits
 
RHEOLOGY Physical pharmaceutics-II notes for B.pharm 4th sem students
RHEOLOGY Physical pharmaceutics-II notes for B.pharm 4th sem studentsRHEOLOGY Physical pharmaceutics-II notes for B.pharm 4th sem students
RHEOLOGY Physical pharmaceutics-II notes for B.pharm 4th sem students
Himanshu Rai
 
Mule event processing models | MuleSoft Mysore Meetup #47
Mule event processing models | MuleSoft Mysore Meetup #47Mule event processing models | MuleSoft Mysore Meetup #47
Mule event processing models | MuleSoft Mysore Meetup #47
MysoreMuleSoftMeetup
 
Beyond Degrees - Empowering the Workforce in the Context of Skills-First.pptx
Beyond Degrees - Empowering the Workforce in the Context of Skills-First.pptxBeyond Degrees - Empowering the Workforce in the Context of Skills-First.pptx
Beyond Degrees - Empowering the Workforce in the Context of Skills-First.pptx
EduSkills OECD
 
Film vocab for eal 3 students: Australia the movie
Film vocab for eal 3 students: Australia the movieFilm vocab for eal 3 students: Australia the movie
Film vocab for eal 3 students: Australia the movie
Nicholas Montgomery
 
Advanced Java[Extra Concepts, Not Difficult].docx
Advanced Java[Extra Concepts, Not Difficult].docxAdvanced Java[Extra Concepts, Not Difficult].docx
Advanced Java[Extra Concepts, Not Difficult].docx
adhitya5119
 
Pengantar Penggunaan Flutter - Dart programming language1.pptx
Pengantar Penggunaan Flutter - Dart programming language1.pptxPengantar Penggunaan Flutter - Dart programming language1.pptx
Pengantar Penggunaan Flutter - Dart programming language1.pptx
Fajar Baskoro
 
MARY JANE WILSON, A “BOA MÃE” .
MARY JANE WILSON, A “BOA MÃE”           .MARY JANE WILSON, A “BOA MÃE”           .
MARY JANE WILSON, A “BOA MÃE” .
Colégio Santa Teresinha
 
clinical examination of hip joint (1).pdf
clinical examination of hip joint (1).pdfclinical examination of hip joint (1).pdf
clinical examination of hip joint (1).pdf
Priyankaranawat4
 
Chapter wise All Notes of First year Basic Civil Engineering.pptx
Chapter wise All Notes of First year Basic Civil Engineering.pptxChapter wise All Notes of First year Basic Civil Engineering.pptx
Chapter wise All Notes of First year Basic Civil Engineering.pptx
Denish Jangid
 
BÀI TẬP BỔ TRỢ TIẾNG ANH LỚP 9 CẢ NĂM - GLOBAL SUCCESS - NĂM HỌC 2024-2025 - ...
BÀI TẬP BỔ TRỢ TIẾNG ANH LỚP 9 CẢ NĂM - GLOBAL SUCCESS - NĂM HỌC 2024-2025 - ...BÀI TẬP BỔ TRỢ TIẾNG ANH LỚP 9 CẢ NĂM - GLOBAL SUCCESS - NĂM HỌC 2024-2025 - ...
BÀI TẬP BỔ TRỢ TIẾNG ANH LỚP 9 CẢ NĂM - GLOBAL SUCCESS - NĂM HỌC 2024-2025 - ...
Nguyen Thanh Tu Collection
 
Traditional Musical Instruments of Arunachal Pradesh and Uttar Pradesh - RAYH...
Traditional Musical Instruments of Arunachal Pradesh and Uttar Pradesh - RAYH...Traditional Musical Instruments of Arunachal Pradesh and Uttar Pradesh - RAYH...
Traditional Musical Instruments of Arunachal Pradesh and Uttar Pradesh - RAYH...
imrankhan141184
 
UGC NET Exam Paper 1- Unit 1:Teaching Aptitude
UGC NET Exam Paper 1- Unit 1:Teaching AptitudeUGC NET Exam Paper 1- Unit 1:Teaching Aptitude
UGC NET Exam Paper 1- Unit 1:Teaching Aptitude
S. Raj Kumar
 

Recently uploaded (20)

How to Create a More Engaging and Human Online Learning Experience
How to Create a More Engaging and Human Online Learning Experience How to Create a More Engaging and Human Online Learning Experience
How to Create a More Engaging and Human Online Learning Experience
 
How to Make a Field Mandatory in Odoo 17
How to Make a Field Mandatory in Odoo 17How to Make a Field Mandatory in Odoo 17
How to Make a Field Mandatory in Odoo 17
 
math operations ued in python and all used
math operations ued in python and all usedmath operations ued in python and all used
math operations ued in python and all used
 
What is Digital Literacy? A guest blog from Andy McLaughlin, University of Ab...
What is Digital Literacy? A guest blog from Andy McLaughlin, University of Ab...What is Digital Literacy? A guest blog from Andy McLaughlin, University of Ab...
What is Digital Literacy? A guest blog from Andy McLaughlin, University of Ab...
 
ANATOMY AND BIOMECHANICS OF HIP JOINT.pdf
ANATOMY AND BIOMECHANICS OF HIP JOINT.pdfANATOMY AND BIOMECHANICS OF HIP JOINT.pdf
ANATOMY AND BIOMECHANICS OF HIP JOINT.pdf
 
The History of Stoke Newington Street Names
The History of Stoke Newington Street NamesThe History of Stoke Newington Street Names
The History of Stoke Newington Street Names
 
Walmart Business+ and Spark Good for Nonprofits.pdf
Walmart Business+ and Spark Good for Nonprofits.pdfWalmart Business+ and Spark Good for Nonprofits.pdf
Walmart Business+ and Spark Good for Nonprofits.pdf
 
ZK on Polkadot zero knowledge proofs - sub0.pptx
ZK on Polkadot zero knowledge proofs - sub0.pptxZK on Polkadot zero knowledge proofs - sub0.pptx
ZK on Polkadot zero knowledge proofs - sub0.pptx
 
RHEOLOGY Physical pharmaceutics-II notes for B.pharm 4th sem students
RHEOLOGY Physical pharmaceutics-II notes for B.pharm 4th sem studentsRHEOLOGY Physical pharmaceutics-II notes for B.pharm 4th sem students
RHEOLOGY Physical pharmaceutics-II notes for B.pharm 4th sem students
 
Mule event processing models | MuleSoft Mysore Meetup #47
Mule event processing models | MuleSoft Mysore Meetup #47Mule event processing models | MuleSoft Mysore Meetup #47
Mule event processing models | MuleSoft Mysore Meetup #47
 
Beyond Degrees - Empowering the Workforce in the Context of Skills-First.pptx
Beyond Degrees - Empowering the Workforce in the Context of Skills-First.pptxBeyond Degrees - Empowering the Workforce in the Context of Skills-First.pptx
Beyond Degrees - Empowering the Workforce in the Context of Skills-First.pptx
 
Film vocab for eal 3 students: Australia the movie
Film vocab for eal 3 students: Australia the movieFilm vocab for eal 3 students: Australia the movie
Film vocab for eal 3 students: Australia the movie
 
Advanced Java[Extra Concepts, Not Difficult].docx
Advanced Java[Extra Concepts, Not Difficult].docxAdvanced Java[Extra Concepts, Not Difficult].docx
Advanced Java[Extra Concepts, Not Difficult].docx
 
Pengantar Penggunaan Flutter - Dart programming language1.pptx
Pengantar Penggunaan Flutter - Dart programming language1.pptxPengantar Penggunaan Flutter - Dart programming language1.pptx
Pengantar Penggunaan Flutter - Dart programming language1.pptx
 
MARY JANE WILSON, A “BOA MÃE” .
MARY JANE WILSON, A “BOA MÃE”           .MARY JANE WILSON, A “BOA MÃE”           .
MARY JANE WILSON, A “BOA MÃE” .
 
clinical examination of hip joint (1).pdf
clinical examination of hip joint (1).pdfclinical examination of hip joint (1).pdf
clinical examination of hip joint (1).pdf
 
Chapter wise All Notes of First year Basic Civil Engineering.pptx
Chapter wise All Notes of First year Basic Civil Engineering.pptxChapter wise All Notes of First year Basic Civil Engineering.pptx
Chapter wise All Notes of First year Basic Civil Engineering.pptx
 
BÀI TẬP BỔ TRỢ TIẾNG ANH LỚP 9 CẢ NĂM - GLOBAL SUCCESS - NĂM HỌC 2024-2025 - ...
BÀI TẬP BỔ TRỢ TIẾNG ANH LỚP 9 CẢ NĂM - GLOBAL SUCCESS - NĂM HỌC 2024-2025 - ...BÀI TẬP BỔ TRỢ TIẾNG ANH LỚP 9 CẢ NĂM - GLOBAL SUCCESS - NĂM HỌC 2024-2025 - ...
BÀI TẬP BỔ TRỢ TIẾNG ANH LỚP 9 CẢ NĂM - GLOBAL SUCCESS - NĂM HỌC 2024-2025 - ...
 
Traditional Musical Instruments of Arunachal Pradesh and Uttar Pradesh - RAYH...
Traditional Musical Instruments of Arunachal Pradesh and Uttar Pradesh - RAYH...Traditional Musical Instruments of Arunachal Pradesh and Uttar Pradesh - RAYH...
Traditional Musical Instruments of Arunachal Pradesh and Uttar Pradesh - RAYH...
 
UGC NET Exam Paper 1- Unit 1:Teaching Aptitude
UGC NET Exam Paper 1- Unit 1:Teaching AptitudeUGC NET Exam Paper 1- Unit 1:Teaching Aptitude
UGC NET Exam Paper 1- Unit 1:Teaching Aptitude
 

iron deficiency anemia for laboratory students.ppt

  • 1. Iron deficiency anemia Assistant prof .Radfan Saleh
  • 2. Blood Smear Interpretation Assistant prof .Radfan Saleh
  • 3. Normal blood picture Assistant prof .Radfan Saleh
  • 4. Iron stain Assistant prof .Radfan Saleh
  • 5. Blood film, high concentration Assistant prof .Radfan Saleh
  • 6. Blood film, low concentration Assistant prof .Radfan Saleh
  • 7. Iron deficiency is defined as a decreased total iron body content. Iron is vital for all living organisms because it is essential for multiple metabolic processes, including oxygen transport and DNA synthesis. Assistant prof .Radfan Saleh
  • 8. Iron balance is achieved largely by regulation of iron absorption in the proximal small intestine. Factors that enhance iron absorption . Facilitators: ascorbate, citrate, amino acids, iron deficiency Assistant prof .Radfan Saleh
  • 9. Factors that prevent iron absorption. Inhibitors: , tannins, iron overload, antacids Assistant prof .Radfan Saleh
  • 10. Causes of iron deficiency :- chronic blood loss increased iron requirement iron malabsorption inadequate dietary intake 1- chronic blood loss:- the most common causes of iron deficiency in adult are :- - Occult bleeding from the gastrointestinal tract. - Blood loss caused by menstruation or pregnancy and including birth.
  • 11. A) gastrointestinal bleeding: occult blood loss from the gastrointestinal tract can be chronic without displaying any symptoms and may go undetected until the patient presents with symptoms of anemia this is may be due to :- peptic ulcer, hook worm infection, malignancies of stomach or colon. B) uterine bleeding:- menstrual bleeding is the most common cause of iron deficiency in woman . The average amount of blood lost during each menstrual cycle is about 45 ml which represents about 25mg of iron lost each month. C) other sources of bleeding:- this is may present with chronic blood loss that result from hematuria or hemoglobinuria.
  • 12. 2- increases in the physiologic requirement for iron :- This is due to increases in the requirements for iron that exceed the amounts of iron normally available in the diet . infancy:- in the infant iron deficiency usually result from an unsupplemented diet of milk that is not capably of providing enough iron for erythropoiesis. Adolescence:- iron deficiency is result from the increased demands during period of increased growth. Pregnancy and lactation:- although menstruation ceases during pregnancy, there is an increased demand for iron because of fetal growth and an increased maternal red cell mass during pregnancy
  • 13. 3- iron malabsorption :- Iron deficiency may be result from two absorption deficiency :- A) malabsorption syndromes this due to damage in the iron-absorbing mucosal cells of the duodenum. B) subtotal gastrectomy:-gastric acid may not be available for converting insoluble dietary ferric iron to the soluble ferrous form that can be absorbed and transport rapidly through the duodenum. 4- inadequate iron intake . Source of iron:- rich source (liver, heart, kidney) Good source (leafy vegetable, fish, fruit )
  • 14. Schistosomes & Eggs Assistant prof .Radfan Saleh
  • 15. iron deficiency anemia Assistant prof .Radfan Saleh
  • 16. iron deficiency anemia Assistant prof .Radfan Saleh
  • 17. Distinct microcytosis (compare with size of the lymphocyte). Some of erythrocytes are hypochromic. A few pencil shaped cells are seen Assistant prof .Radfan Saleh
  • 18. The arrow shows elongated pencil - like cell Assistant prof .Radfan Saleh
  • 19. The arrow shows elongated pencil - like cell Assistant prof .Radfan Saleh
  • 20. severe iron deficiency anemia Assistant prof .Radfan Saleh
  • 21. Iron stain Assistant prof .Radfan Saleh
  • 22. • marrow particle stained for detection of free iron shows no trace of the element . Assistant prof .Radfan Saleh
  • 23. Iron stain, depleted stores Assistant prof .Radfan Saleh
  • 24. Iron stain, depleted stores Assistant prof .Radfan Saleh
  • 25. Iron deficient Dual population treated Assistant prof .Radfan Saleh
  • 26. Diagnosis History and clinical examination of the patient, specially dietary history Peripheral blood picture, hypochromic microcytic anemia Measurement of Serum iron Serum ferritin Normal blood levels are 30-300 ng/mL for males and 15- 200 ng/mL for females Stainable iron in bone marrow Assistant prof .Radfan Saleh
  • 27. Serum Iron (SI) • Men: 65 to 176 µg/ dL • Women: 50 to 170 µg/ dL • Newborns: 100 to 250 µg/ dL • Children: 50 to 120 µg/ dL • : µg/ dL TIBC:240-450 • Transferrin saturation: 20-50% Assistant prof .Radfan Saleh
  • 28. CBC, iron deficiency anemia. Microcytosis is indicated by the low MCV. Hypochromia correlates here with the low MCH. Assistant prof .Radfan Saleh
  • 29. Clinical features anemia The most common symptoms of anemia are pallor, fatigue and dyspnea Assistant prof .Radfan Saleh
  • 35. Diagnosis of iron deficiency anemia:- 1- peripheral blood findings:- hemoglobin :- 5 – 10 g/dl. haematocrit :- low MCV low MCH 2- peripheral blood smears:- microcytic, hypochromic red cells. poikilocytosis, which are abnormal shaped RBCs Pencil shape are feature in iron deficiency anemia
  • 36.
  • 37.
  • 38. Causes of Anemia of Chronic Disease Any disease condition that is associated with inflammation, and that lasts more than 1 or 2 months, can cause anemia of chronic disease. In some cases, the inflammation is obvious (chronic infections or rheumatic disorders, for example); in other cases, the inflammation is less obvious (malignancies). Chronic illnesses that are not associated with inflammation (for example, hypertension or diabetes mellitus) are not usually associated with the anemia of chronic disease.
  • 39. Laboratory Diagnosis 1- The anemia due to chronic disease is usually mild or moderate: blood hemoglobin levels ≥8 to 10 g/dL. However, the anemia may be more severe in chronic illnesses with marked inflammation. The anemia is usually normocytic and normochromic but can be microcytic in severe cases. 2- MCV is usually only mildly decreased (≥70 fL). 3- The reticulocyte count is low. 4- erythrocyte sedimentation rate are usually increased.