Interesting cases in neuroradiology SOL
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This document discusses evaluating and characterizing space occupying lesions in the brain. It lists potential causes of such lesions including tumors, infections, hemorrhages, infarcts, demyelinating diseases, and vascular lesions. Differential diagnoses are provided for specific cases, such as a 79 year old woman with bleeding from her left ear and a pontine lesion. The document emphasizes detecting, localizing, and determining the nature of any space occupying lesions found.
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The benefits of an ePCR solution should extend to the whole EMS organization, not just certain groups of people or certain departments. It should provide more than just a form for entering and a database for storing information. It should also include a workflow of how information is communicated, used and stored across the entire organization.
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- Video recording of this lecture in English language: https://youtu.be/Pt1nA32sdHQ
- Video recording of this lecture in Arabic language: https://youtu.be/uFdc9F0rlP0
- Link to download the book free: https://nephrotube.blogspot.com/p/nephrotube-nephrology-books.html
- Link to NephroTube website: www.NephroTube.com
- Link to NephroTube social media accounts: https://nephrotube.blogspot.com/p/join-nephrotube-on-social-media.html
Cell Therapy Expansion and Challenges in Autoimmune Disease
There is increasing confidence that cell therapies will soon play a role in the treatment of autoimmune disorders, but the extent of this impact remains to be seen. Early readouts on autologous CAR-Ts in lupus are encouraging, but manufacturing and cost limitations are likely to restrict access to highly refractory patients. Allogeneic CAR-Ts have the potential to broaden access to earlier lines of treatment due to their inherent cost benefits, however they will need to demonstrate comparable or improved efficacy to established modalities.
In addition to infrastructure and capacity constraints, CAR-Ts face a very different risk-benefit dynamic in autoimmune compared to oncology, highlighting the need for tolerable therapies with low adverse event risk. CAR-NK and Treg-based therapies are also being developed in certain autoimmune disorders and may demonstrate favorable safety profiles. Several novel non-cell therapies such as bispecific antibodies, nanobodies, and RNAi drugs, may also offer future alternative competitive solutions with variable value propositions.
Widespread adoption of cell therapies will not only require strong efficacy and safety data, but also adapted pricing and access strategies. At oncology-based price points, CAR-Ts are unlikely to achieve broad market access in autoimmune disorders, with eligible patient populations that are potentially orders of magnitude greater than the number of currently addressable cancer patients. Developers have made strides towards reducing cell therapy COGS while improving manufacturing efficiency, but payors will inevitably restrict access until more sustainable pricing is achieved.
Despite these headwinds, industry leaders and investors remain confident that cell therapies are poised to address significant unmet need in patients suffering from autoimmune disorders. However, the extent of this impact on the treatment landscape remains to be seen, as the industry rapidly approaches an inflection point.
MERCURY GROUP.BHMS.MATERIA MEDICA.HOMOEOPATHY
Mercurius is named after the roman god mercurius, the god of trade and science. The planet mercurius is named after the same god. Mercurius is sometimes called hydrargyrum, means ‘watery silver’. Its shine and colour are very similar to silver, but mercury is a fluid at room temperatures. The name quick silver is a translation of hydrargyrum, where the word quick describes its tendency to scatter away in all directions.
The droplets have a tendency to conglomerate to one big mass, but on being shaken they fall apart into countless little droplets again. It is used to ignite explosives, like mercury fulminate, the explosive character is one of its general themes.
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Interesting cases in neuroradiology SOL
- 1. Space occupying lesion Arunnit Boonrod
- 2. • Detection • Localization • Characterization
- 3. • Tumor • Infection • Hematoma • Infarction • Demyelinating disease • Vascular lesion
- 6. ?Benign or Malignant hemorrhage?
- 9. ?Nature? • Tumor • Infection • Hematoma • Infarction • Demyelinating disease • Vascular lesion
- 11. • Tumor • Infection • Hematoma • Infarction • Demyelinating disease • Vascular lesion
- 14. ?Nature? • Tumor • Infection • Hematoma • Infarction • Demyelinating disease • Vascular lesion
- 17. ?Nature? • Tumor • Infection • Hematoma • Infarction • Demyelinating disease • Vascular lesion
- 19. 79 yo woman with bleeding per left ear
- 21. ?What are DDx? • Paraganglioma • Meningioma • Schwannoma
- 22. Paraganglioma Schwannoma Meningioma Ill define lytic Smooth pressure erosion Hyperosteosis Salt and pepper appearance Avidly enhance Bright T2w Avidly enhance Isosignal Avidly enhance
- 24. ?Nature? • Tumor • Infection • Hematoma • Infarction • Demyelinating disease • Vascular lesion
- 28. ?Nature? • Tumor • Infection • Hematoma • Infarction • Demyelinating disease • Vascular lesion
- 29. DDX pontine lesion • Pontine glioma • Pontine infarction • Demyelinating lesion. • Central pontine myelinolysis.
- 34. The end Thank you for your attention