luisetto m et al mindset kinetics and some depression status a new quantitative model under biochemical - toxicology approach insights depress anxiety.2018,impact #PSYC,#neuro,#science,#tox,#go gle,HIGH,#cognitive, COLUMBIA UNIV. LIBRARY, SCILIT, WORLDCAT
The document discusses depression from the perspective of mindset kinetics and biochemical/toxicological factors. It proposes that depression may be related to the amount and quality of negative thinking, and how the brain/mind responds to and manages stress over time. The document suggests applying concepts from fields like biochemistry (e.g. kinetics, saturation limits) to better understand phenomena like depression. It argues that depression should be viewed as influenced by multiple interacting factors beyond just neurotransmitters, and that historical and social factors may influence what is considered a mental disorder.
This document discusses a proposed new quantitative model for understanding some cases of depression from a biochemical and toxicological perspective, focusing on the concept of "mindset kinetics".
The summary is:
1. The document proposes applying concepts from fields like biochemistry and kinetics to better understand how the brain and mind respond to and manage stress, with a high amount or duration of negative stress potentially leading to depression in susceptible individuals.
2. It discusses how mindfulness practices and other disciplines help exclude external stressors and suggests depression may be related more to the quality and amount of negative thinking over time.
3. The document reviews literature on factors like stress management skills, coping strategies, and mindfulness that could influence depressive symptoms and
1) The document discusses how quantitative methods involving biochemistry, toxicology, and imaging could help evaluate amygdala and limbic system activation in legal settings to better understand criminal behavior and mental states.
2) Literature on the topic suggests pathological amygdala and limbic system activation could be objectively diagnosed and potentially treated similarly to other physiological conditions if validated assessment methods were established.
3) Studies have found abnormal metabolism and neurochemistry in the amygdala of individuals with conditions like borderline personality disorder that could relate to symptoms like impulsivity and emotional dysregulation.
1. The document proposes a new theory of how consciousness interacts with matter by suggesting that the appraisal of a stimulus creates a new quantum entity.
2. This new entity possesses a quantum of thermal energy, and if the stimulus is appraised as a threat, the entity's temperature will be lower than the appraiser's body temperature.
3. Heat transfer then occurs from the body to the entity, causing threat-induced hypothermia and changes in neurotransmission that produce the psychological and physiological effects of stress.
This document summarizes research on using quantitative methods and physiological measurements to help understand criminal behavior and assess culpability in legal cases. It reviews literature showing that conditions like abnormal amygdala and limbic system activation can influence emotions and impulse control. The authors argue that objectively measuring these systems could provide additional context for legal decisions, rather than as direct evidence. They propose developing diagnostic tests to characterize stress responses and treatments for pathological conditions. While neuroscience hasn't yet determined criminal responsibility, it may help challenge understandings as the field advances.
The two functions systems that have contributed to the origin of Psychology has been emotional arousal and cognitive processes. Emotional arousal has provided the basic driving f orce, whereas cognitive processing contributed to making sensory-motor contacts with reality. Complex cognitive processing facilitated extensive knowledge base of the sensory-motor contacts, as well as helped to create virtual realities. Emotional arousal supported the genesis of responses and actions, as per the cognitive judgments made in the system. The article deals with brief account of the complex nature of interactions between the two systems and how psychology - the mind and behavior emerged from the interactions.
This document provides an overview of different types of psychological therapies discussed in Chapter 15 of the 9th edition of the Psychology textbook by David Myers. It summarizes various therapeutic approaches including psychoanalysis, humanistic therapies, behavior therapies, cognitive therapies, group/family therapies, and biomedical therapies. For each approach, it briefly describes key theorists, methods, applications, and criticisms. It also evaluates the effectiveness of psychotherapy and compares different therapies for treating specific disorders.
Meditation as Medication Mastering the Art of Mindfulness (Long Version)Daryush Parvinbenam
Meditation as Medication Mastering the Art of Mindfulness (Long Version)
By: Daryush Parvinbenam M.Ed., M.A., LPCCS, LICDC
Appleseed Community Mental Health Center
R.S.V.P Conference
Sept 29, 2010
The Neurobiology of Touch and Trauma Somatic Experiencing from Dysregulation ...Michael Changaris
This paper explores the role of touch in treatment. It explores the neurobiological impact of touch with a focus on the main neurological systems activated in touch. The paper attempts to outline tools to reduce symptoms of trauma through touch.
This document discusses a proposed new quantitative model for understanding some cases of depression from a biochemical and toxicological perspective, focusing on the concept of "mindset kinetics".
The summary is:
1. The document proposes applying concepts from fields like biochemistry and kinetics to better understand how the brain and mind respond to and manage stress, with a high amount or duration of negative stress potentially leading to depression in susceptible individuals.
2. It discusses how mindfulness practices and other disciplines help exclude external stressors and suggests depression may be related more to the quality and amount of negative thinking over time.
3. The document reviews literature on factors like stress management skills, coping strategies, and mindfulness that could influence depressive symptoms and
1) The document discusses how quantitative methods involving biochemistry, toxicology, and imaging could help evaluate amygdala and limbic system activation in legal settings to better understand criminal behavior and mental states.
2) Literature on the topic suggests pathological amygdala and limbic system activation could be objectively diagnosed and potentially treated similarly to other physiological conditions if validated assessment methods were established.
3) Studies have found abnormal metabolism and neurochemistry in the amygdala of individuals with conditions like borderline personality disorder that could relate to symptoms like impulsivity and emotional dysregulation.
1. The document proposes a new theory of how consciousness interacts with matter by suggesting that the appraisal of a stimulus creates a new quantum entity.
2. This new entity possesses a quantum of thermal energy, and if the stimulus is appraised as a threat, the entity's temperature will be lower than the appraiser's body temperature.
3. Heat transfer then occurs from the body to the entity, causing threat-induced hypothermia and changes in neurotransmission that produce the psychological and physiological effects of stress.
This document summarizes research on using quantitative methods and physiological measurements to help understand criminal behavior and assess culpability in legal cases. It reviews literature showing that conditions like abnormal amygdala and limbic system activation can influence emotions and impulse control. The authors argue that objectively measuring these systems could provide additional context for legal decisions, rather than as direct evidence. They propose developing diagnostic tests to characterize stress responses and treatments for pathological conditions. While neuroscience hasn't yet determined criminal responsibility, it may help challenge understandings as the field advances.
The two functions systems that have contributed to the origin of Psychology has been emotional arousal and cognitive processes. Emotional arousal has provided the basic driving f orce, whereas cognitive processing contributed to making sensory-motor contacts with reality. Complex cognitive processing facilitated extensive knowledge base of the sensory-motor contacts, as well as helped to create virtual realities. Emotional arousal supported the genesis of responses and actions, as per the cognitive judgments made in the system. The article deals with brief account of the complex nature of interactions between the two systems and how psychology - the mind and behavior emerged from the interactions.
This document provides an overview of different types of psychological therapies discussed in Chapter 15 of the 9th edition of the Psychology textbook by David Myers. It summarizes various therapeutic approaches including psychoanalysis, humanistic therapies, behavior therapies, cognitive therapies, group/family therapies, and biomedical therapies. For each approach, it briefly describes key theorists, methods, applications, and criticisms. It also evaluates the effectiveness of psychotherapy and compares different therapies for treating specific disorders.
Meditation as Medication Mastering the Art of Mindfulness (Long Version)Daryush Parvinbenam
Meditation as Medication Mastering the Art of Mindfulness (Long Version)
By: Daryush Parvinbenam M.Ed., M.A., LPCCS, LICDC
Appleseed Community Mental Health Center
R.S.V.P Conference
Sept 29, 2010
The Neurobiology of Touch and Trauma Somatic Experiencing from Dysregulation ...Michael Changaris
This paper explores the role of touch in treatment. It explores the neurobiological impact of touch with a focus on the main neurological systems activated in touch. The paper attempts to outline tools to reduce symptoms of trauma through touch.
The Hidden Agenda: Cognitive processes in addictiondrfrankryan
1. The document discusses cognitive processes like attentional biases and impaired executive function as latent vulnerability factors that can increase drug craving and relapse risk in addiction.
2. Treatment should focus on modifying these cognitive processes through strategies like cognitive rehabilitation, impulse control training, and reversing cognitive biases.
3. Translating cognitive psychology findings into effective clinical applications is challenging but treatments combining cognitive and behavioral approaches may be most effective in addressing addiction at both implicit and explicit cognitive levels.
Progressive muscle relaxation and other relaxation techniques aim to reduce stress and anxiety in three ways: as a preventative measure, as a treatment for stress-related conditions, and as a coping skill. Relaxation methods target the autonomic nervous system, endocrine system, and skeletal musculature to induce a relaxation response. While early techniques like Jacobson's progressive muscle relaxation took significant time, modified versions like Bernstein and Borkovec's progressive relaxation training condensed the process into shorter sessions. Other approaches include passive muscular relaxation, applied relaxation, and breathing techniques. Relaxation training provides benefits for stress, hypertension, pain, insomnia, and other conditions.
This document summarizes several theories related to message reception and processing. It discusses:
1) Osgood's theory of meaning, which views meaning as learned associations and proposes three basic dimensions of meaning: evaluation, activity, and potency.
2) Attribution theory, which examines how people infer causes of behavior based on perceptions of situational and personal factors.
3) Information integration theory, which views attitudes as elements stored in memory that are shaped by the valence (supportive or unsupportive) and weight (credibility) assigned to new information.
Treatments for Post-Traumatic Stress Disorder
Post-traumatic stress disorder (PTSD) is a medical condition that affects a person’s thoughts, feelings and behaviors.
There are many treatments available; however, the most common treatments are psychotherapy and/or medication.
Psychotherapy, also known as talk therapy, is a treatment in which people work with trained behavorial health
providers to discuss their problems and learn new skills. While there are a variety of psychotherapies available to treat
PTSD, some have been proven to be more effective than others. There are also several medications that are effective
in treating PTSD. This handout provides basic information on treatments recommended as most effective by the VA/
DoD clinical practice guideline for PTSD.
Implicit cognitive processes in the addiction clinicdrfrankryan
The document discusses implicit cognitive processes in addiction treatment. It argues that implicit processes underlie involuntary aspects of addiction and are potential targets for modification through existing and new treatments. Specifically, it suggests that addressing implicit biases and improving executive control can enhance treatment outcomes by reducing cue reactivity and preoccupation with drug cues. A number of cognitive and behavioral techniques are proposed that aim to increase cognitive control and reverse automatic tendencies, such as cognitive bias modification and implementation intentions.
The document discusses the behavioral approach to counseling. Some key points:
- Behaviorism views behavior as responses to environmental stimuli and believes behaviors are learned through conditioning. John Watson and B.F. Skinner were major proponents of behaviorism.
- The main goal of behavior therapy is to increase positive behaviors and engagement in reinforcing activities through structured programs that measure behaviors and increase chances of positive experiences.
- Techniques include systematic desensitization, exposure therapies, aversion therapy, and modeling to change maladaptive behaviors without focusing on underlying causes. Advantages include learning to act instead of react and changing brain physiology, while limitations include ignoring self and treating only symptoms.
Meditation and Mindfulness Report 2015Minae Nemoto
1) Meditation has numerous physical, mental, and social benefits including reducing stress hormones like cortisol, lowering blood pressure, reducing anxiety and depression, and improving brain function and memory.
2) Regular meditation practice of even just 10 minutes per day can help decrease one's vulnerability to stress and promote positive emotions. This allows individuals to approach challenges with greater strength and clarity.
3) Meditation involves focusing attention on breathing to calm the mind and increase oxygen in the bloodstream, boosting hormones like oxytocin that promote feelings of comfort and connection.
This summary provides an overview of the key points from the document in 3 sentences:
The document discusses three cognitive perspectives - cognitive, humanistic, and sociocultural - and how they shed light on understanding behavior. For the cognitive perspective, it examines how biological and thought processes influence behavior. The humanistic perspective views behavior as acquiring knowledge to understand one's environment and make appropriate choices. Finally, the sociocultural perspective sees behavior as observable and influenced by imitating others and following social and cultural norms.
The document summarizes research on the neurobiology of spirituality. Studies using neuroimaging techniques like PET, MRI, and SPECT have found that spiritual practices like meditation are associated with increased activity in the prefrontal cortex and decreased activity in the parietal lobe. Meditation appears to begin by activating the prefrontal cortex, which is involved in focus and attention. Over time, meditation may lead to transient hypofrontality. The prefrontal regions also mediate preparedness for religious experiences and cognitive processing of such experiences. Neurochemical changes from meditation involve neurotransmitter systems like dopamine. Overall, the evidence suggests spiritual practices engage multiple brain regions and can produce physiological and neurochemical alterations.
Scientific Theories of Hypnosis discusses several key theories that have been proposed to explain the phenomenon of hypnosis:
- State theories such as Hilgard's Neodissociation Theory propose that hypnosis involves a dissociation of control systems in the brain. Non-state theories such as Social-Cognitive Theory view hypnosis as influenced more by expectations and social factors rather than changes in brain states.
- More recent theories attempt to integrate aspects of state and non-state approaches. Woody and Sadler's Integrated Dissociative Theory proposes weakening of connections between different control systems. Cold Control Theory distinguishes between being in a mental state and being aware of it.
This document presents a mindfulness coaching model consisting of four key modalities: mind, body, cognition, and emotion. These modalities are represented by a square with the mindfulness coaching tools and techniques on a wheel in the center representing positive change or dynamic stability once integrated. The model is based on neuroplasticity and the Schwartz-Rock dynamic stability formula. Mindfulness practices cultivate high attention density and veto power, influencing the formula and facilitating positive change through neural pathway development. The document defines the mind and discusses how mindfulness can be conceptualized within the model's framework.
Resource guide template 2015_instructions unit 9 final projectLydia Robinson-Moody
This document is a resource guide for a stress management and prevention program consisting of 9 units. It provides information on the nature of stress and its links to health issues. It also covers the physiology of stress including the nervous, endocrine, and immune systems' roles. Journal writing exercises are included to help participants assess and track their stress levels over various situations throughout the course.
This document introduces energy medicine and discusses some of its key concepts and examples. It argues that energy medicine approaches the body as an energy and information system rather than a mechanical device. Some examples of energy medicine techniques mentioned are acupuncture, homeopathy, and energy psychology. The document also discusses how energy medicine and its understanding of the body are still emerging areas of science.
The stress proof brain master your emotional response to stress using mindful...An Le Truong
Lê Trường An – Dịch giả – Tác giả – Marketer – chuyên thực hiện các dự án SEO, Social Media, Dịch thuật và xuất bản nội dung. Ngoài ra, Lê Trường An liên tục cập nhật nội dung blog với các chủ đề SEO, Marketing và nhiều hơn nữa…
---
Content Creator Lê Trường An
Chuyên viên Marketing – Tác giả - Dịch giả tại letruongan.com
Chuyên viên Marketing tại BrainCoach
Chuyên viên Content Marketing tại FoogleSEO
Dịch vụ Marketing – SEO – Content Marketing
This document discusses self-healing and self-organization from the perspective of traditional Chinese medicine. It views health as a dynamic state where a system is open to information exchange without losing its characteristics. Disease occurs when a system is pushed beyond a threshold by triggers. Symptoms represent attractors that can be used for diagnosis and treatment. Treatment aims to design interventions for complex systems using methods like biomarker fingerprinting to address multiple subtypes of diseases like diabetes.
According to Antonio Damasio, the emotional process begins with conscious considerations about the object in the form of mental images. These images correspond to a neural substrate (topographic representations) influenced by the dispositional representations. At the unconscious level, the networks in the prefrontal cortex respond automatically and involuntarily to the signals derived from the processing of the above images, according to the dispositional representations, acquired based on personal experience rather than innate.
DOI: 10.13140/RG.2.2.21624.06401
This document discusses equine therapy as a model for healing from crisis and trauma. It provides an overview of equine therapy, including how it works, the roles of the equine therapist and horse handler, definitions of equine assisted psychotherapy and learning, populations it can benefit, what a typical session involves, and research supporting its effectiveness, especially for treating post-traumatic stress disorder in veterans.
This poster presentation discusses applying biochemical and toxicological principles to better understand mindset kinetics and its role in mental disorders, stress management, and behavior. It proposes that the brain and mind can be viewed through a kinetics lens and analyzed using principles from fields like quantum theory, Eli Goldratt's theory of constraints, and pharmacology. Quantifying factors like stress levels, exposure time, and an individual's buffer properties may provide a new experimental method for understanding resilience and the limits of stress management between the brain and mind. The goal is to draw connections between psychology, neuroscience, and other disciplines to gain a more holistic view of these phenomena.
This document discusses mindset kinetics under a toxicological aspect. It explores how factors like the amount, duration, and chronicity of stress, as well as individual resilience, can impact physiological responses. The kinetics of the mindset and how emotional processing occurs more rapidly than rational thinking are also examined. A number of techniques for improving resilience abilities are mentioned, and it is argued that kinetic and toxicological evaluations can provide insight into pathophysiological mechanisms and help develop new pharmacological strategies.
This document summarizes a paper that examines mindset kinetics under toxicological aspects. It discusses how the amount and kinetics of stress and stimuli can impact human conditions, and how not just single stresses but cumulative stress over time can make situations more severe. It explores individual differences in resilience, compares mindset kinetics to metabolic kinetics, and discusses whether we can think of a saturation point for handling high stress levels. The paper also reviews how emotional intelligence impacts work ability and considers approaches to improving resilience skills to better manage stress. It argues these situations should be evaluated using a kinetic-toxicological lens to understand the physiological mechanisms.
The Hidden Agenda: Cognitive processes in addictiondrfrankryan
1. The document discusses cognitive processes like attentional biases and impaired executive function as latent vulnerability factors that can increase drug craving and relapse risk in addiction.
2. Treatment should focus on modifying these cognitive processes through strategies like cognitive rehabilitation, impulse control training, and reversing cognitive biases.
3. Translating cognitive psychology findings into effective clinical applications is challenging but treatments combining cognitive and behavioral approaches may be most effective in addressing addiction at both implicit and explicit cognitive levels.
Progressive muscle relaxation and other relaxation techniques aim to reduce stress and anxiety in three ways: as a preventative measure, as a treatment for stress-related conditions, and as a coping skill. Relaxation methods target the autonomic nervous system, endocrine system, and skeletal musculature to induce a relaxation response. While early techniques like Jacobson's progressive muscle relaxation took significant time, modified versions like Bernstein and Borkovec's progressive relaxation training condensed the process into shorter sessions. Other approaches include passive muscular relaxation, applied relaxation, and breathing techniques. Relaxation training provides benefits for stress, hypertension, pain, insomnia, and other conditions.
This document summarizes several theories related to message reception and processing. It discusses:
1) Osgood's theory of meaning, which views meaning as learned associations and proposes three basic dimensions of meaning: evaluation, activity, and potency.
2) Attribution theory, which examines how people infer causes of behavior based on perceptions of situational and personal factors.
3) Information integration theory, which views attitudes as elements stored in memory that are shaped by the valence (supportive or unsupportive) and weight (credibility) assigned to new information.
Treatments for Post-Traumatic Stress Disorder
Post-traumatic stress disorder (PTSD) is a medical condition that affects a person’s thoughts, feelings and behaviors.
There are many treatments available; however, the most common treatments are psychotherapy and/or medication.
Psychotherapy, also known as talk therapy, is a treatment in which people work with trained behavorial health
providers to discuss their problems and learn new skills. While there are a variety of psychotherapies available to treat
PTSD, some have been proven to be more effective than others. There are also several medications that are effective
in treating PTSD. This handout provides basic information on treatments recommended as most effective by the VA/
DoD clinical practice guideline for PTSD.
Implicit cognitive processes in the addiction clinicdrfrankryan
The document discusses implicit cognitive processes in addiction treatment. It argues that implicit processes underlie involuntary aspects of addiction and are potential targets for modification through existing and new treatments. Specifically, it suggests that addressing implicit biases and improving executive control can enhance treatment outcomes by reducing cue reactivity and preoccupation with drug cues. A number of cognitive and behavioral techniques are proposed that aim to increase cognitive control and reverse automatic tendencies, such as cognitive bias modification and implementation intentions.
The document discusses the behavioral approach to counseling. Some key points:
- Behaviorism views behavior as responses to environmental stimuli and believes behaviors are learned through conditioning. John Watson and B.F. Skinner were major proponents of behaviorism.
- The main goal of behavior therapy is to increase positive behaviors and engagement in reinforcing activities through structured programs that measure behaviors and increase chances of positive experiences.
- Techniques include systematic desensitization, exposure therapies, aversion therapy, and modeling to change maladaptive behaviors without focusing on underlying causes. Advantages include learning to act instead of react and changing brain physiology, while limitations include ignoring self and treating only symptoms.
Meditation and Mindfulness Report 2015Minae Nemoto
1) Meditation has numerous physical, mental, and social benefits including reducing stress hormones like cortisol, lowering blood pressure, reducing anxiety and depression, and improving brain function and memory.
2) Regular meditation practice of even just 10 minutes per day can help decrease one's vulnerability to stress and promote positive emotions. This allows individuals to approach challenges with greater strength and clarity.
3) Meditation involves focusing attention on breathing to calm the mind and increase oxygen in the bloodstream, boosting hormones like oxytocin that promote feelings of comfort and connection.
This summary provides an overview of the key points from the document in 3 sentences:
The document discusses three cognitive perspectives - cognitive, humanistic, and sociocultural - and how they shed light on understanding behavior. For the cognitive perspective, it examines how biological and thought processes influence behavior. The humanistic perspective views behavior as acquiring knowledge to understand one's environment and make appropriate choices. Finally, the sociocultural perspective sees behavior as observable and influenced by imitating others and following social and cultural norms.
The document summarizes research on the neurobiology of spirituality. Studies using neuroimaging techniques like PET, MRI, and SPECT have found that spiritual practices like meditation are associated with increased activity in the prefrontal cortex and decreased activity in the parietal lobe. Meditation appears to begin by activating the prefrontal cortex, which is involved in focus and attention. Over time, meditation may lead to transient hypofrontality. The prefrontal regions also mediate preparedness for religious experiences and cognitive processing of such experiences. Neurochemical changes from meditation involve neurotransmitter systems like dopamine. Overall, the evidence suggests spiritual practices engage multiple brain regions and can produce physiological and neurochemical alterations.
Scientific Theories of Hypnosis discusses several key theories that have been proposed to explain the phenomenon of hypnosis:
- State theories such as Hilgard's Neodissociation Theory propose that hypnosis involves a dissociation of control systems in the brain. Non-state theories such as Social-Cognitive Theory view hypnosis as influenced more by expectations and social factors rather than changes in brain states.
- More recent theories attempt to integrate aspects of state and non-state approaches. Woody and Sadler's Integrated Dissociative Theory proposes weakening of connections between different control systems. Cold Control Theory distinguishes between being in a mental state and being aware of it.
This document presents a mindfulness coaching model consisting of four key modalities: mind, body, cognition, and emotion. These modalities are represented by a square with the mindfulness coaching tools and techniques on a wheel in the center representing positive change or dynamic stability once integrated. The model is based on neuroplasticity and the Schwartz-Rock dynamic stability formula. Mindfulness practices cultivate high attention density and veto power, influencing the formula and facilitating positive change through neural pathway development. The document defines the mind and discusses how mindfulness can be conceptualized within the model's framework.
Resource guide template 2015_instructions unit 9 final projectLydia Robinson-Moody
This document is a resource guide for a stress management and prevention program consisting of 9 units. It provides information on the nature of stress and its links to health issues. It also covers the physiology of stress including the nervous, endocrine, and immune systems' roles. Journal writing exercises are included to help participants assess and track their stress levels over various situations throughout the course.
This document introduces energy medicine and discusses some of its key concepts and examples. It argues that energy medicine approaches the body as an energy and information system rather than a mechanical device. Some examples of energy medicine techniques mentioned are acupuncture, homeopathy, and energy psychology. The document also discusses how energy medicine and its understanding of the body are still emerging areas of science.
The stress proof brain master your emotional response to stress using mindful...An Le Truong
Lê Trường An – Dịch giả – Tác giả – Marketer – chuyên thực hiện các dự án SEO, Social Media, Dịch thuật và xuất bản nội dung. Ngoài ra, Lê Trường An liên tục cập nhật nội dung blog với các chủ đề SEO, Marketing và nhiều hơn nữa…
---
Content Creator Lê Trường An
Chuyên viên Marketing – Tác giả - Dịch giả tại letruongan.com
Chuyên viên Marketing tại BrainCoach
Chuyên viên Content Marketing tại FoogleSEO
Dịch vụ Marketing – SEO – Content Marketing
This document discusses self-healing and self-organization from the perspective of traditional Chinese medicine. It views health as a dynamic state where a system is open to information exchange without losing its characteristics. Disease occurs when a system is pushed beyond a threshold by triggers. Symptoms represent attractors that can be used for diagnosis and treatment. Treatment aims to design interventions for complex systems using methods like biomarker fingerprinting to address multiple subtypes of diseases like diabetes.
According to Antonio Damasio, the emotional process begins with conscious considerations about the object in the form of mental images. These images correspond to a neural substrate (topographic representations) influenced by the dispositional representations. At the unconscious level, the networks in the prefrontal cortex respond automatically and involuntarily to the signals derived from the processing of the above images, according to the dispositional representations, acquired based on personal experience rather than innate.
DOI: 10.13140/RG.2.2.21624.06401
This document discusses equine therapy as a model for healing from crisis and trauma. It provides an overview of equine therapy, including how it works, the roles of the equine therapist and horse handler, definitions of equine assisted psychotherapy and learning, populations it can benefit, what a typical session involves, and research supporting its effectiveness, especially for treating post-traumatic stress disorder in veterans.
Carrie Rolla - Equine Therapy Powerpoint - Dr. Marlo
Similar to luisetto m et al mindset kinetics and some depression status a new quantitative model under biochemical - toxicology approach insights depress anxiety.2018,impact #PSYC,#neuro,#science,#tox,#go gle,HIGH,#cognitive, COLUMBIA UNIV. LIBRARY, SCILIT, WORLDCAT
This poster presentation discusses applying biochemical and toxicological principles to better understand mindset kinetics and its role in mental disorders, stress management, and behavior. It proposes that the brain and mind can be viewed through a kinetics lens and analyzed using principles from fields like quantum theory, Eli Goldratt's theory of constraints, and pharmacology. Quantifying factors like stress levels, exposure time, and an individual's buffer properties may provide a new experimental method for understanding resilience and the limits of stress management between the brain and mind. The goal is to draw connections between psychology, neuroscience, and other disciplines to gain a more holistic view of these phenomena.
This document discusses mindset kinetics under a toxicological aspect. It explores how factors like the amount, duration, and chronicity of stress, as well as individual resilience, can impact physiological responses. The kinetics of the mindset and how emotional processing occurs more rapidly than rational thinking are also examined. A number of techniques for improving resilience abilities are mentioned, and it is argued that kinetic and toxicological evaluations can provide insight into pathophysiological mechanisms and help develop new pharmacological strategies.
This document summarizes a paper that examines mindset kinetics under toxicological aspects. It discusses how the amount and kinetics of stress and stimuli can impact human conditions, and how not just single stresses but cumulative stress over time can make situations more severe. It explores individual differences in resilience, compares mindset kinetics to metabolic kinetics, and discusses whether we can think of a saturation point for handling high stress levels. The paper also reviews how emotional intelligence impacts work ability and considers approaches to improving resilience skills to better manage stress. It argues these situations should be evaluated using a kinetic-toxicological lens to understand the physiological mechanisms.
This document summarizes a study on mindset kinetics under toxicological aspects. It discusses how factors like the amount, duration, and timing of stressors, as well as individual resilience, can impact physiological responses. Specifically, it notes that an imbalanced mindset kinetics without proper stress management can lead to inappropriate responses, and that deeper understanding of these processes could aid new pharmacological strategies. The discussion concludes that properly evaluating stress situations requires considering the type, amount, and kinetics of stressors, alongside individual psychological and genetic factors.
Appetitive vs Aversive Motivation in AddictionPaul Coelho, MD
This document discusses addiction from a neurobiological and motivational perspective. It proposes that addiction involves a cycle of decreased function of brain reward systems and recruitment of antireward systems that progressively worsen. Excessive drug use results in short-term relief of the reward deficit but long-term worsening of neurochemical dysregulations, forming an allostatic state reflected in a chronic deviation of reward set point fueled by dysregulation of reward circuits and recruitment of stress responses. Vulnerability to addiction may involve genetic and developmental factors that sensitize brain antireward systems.
The Importance of Multiple Perspectives in Psychiatry | Crimson PublishersCrimsonpublishersPPrs
This document discusses the importance of considering multiple perspectives in psychiatry when formulating a patient's case. It outlines several perspectives to consider, including the medical model focusing on symptoms, pathologies and treatments; biological perspectives involving neurotransmitters; phenomenological perspectives articulating a patient's subjective experience; psychodynamic perspectives providing a dynamic understanding of a patient's psyche; interpersonal perspectives considering social and cultural influences as well as relationships; behavioral perspectives related to reinforcement and conditioning; and cognitive perspectives related to thoughts and associations. Considering multiple dimensions can provide a more comprehensive understanding of a patient to optimize treatment.
Hypnosis in psychotherapy and hypnosis as psicotherapyAmbrogio Pennati
This document discusses hypnosis from an evolutionary psychology perspective. It argues that hypnosis is an adaptive trait that provided benefits to individuals and groups throughout human evolution. Trance states facilitated group bonding, modulated pain and immune response, and increased healing. Rapport also had adaptive value by enhancing empathy and social learning. The document proposes hypnosis activates inner healing resources through the synergistic effects of rapport and trance. It views Milton Erickson's approach as implicitly evolutionary and recommends future work further integrate clinical hypnosis research with evolutionary theory and neuroscience.
Brain Based Therapy summarizes a new model called BASE that incorporates neuroscience into psychotherapy. BASE stands for brain, attunement, systems of care, and evidence-based treatment. The model views the brain as shaped by relationships and experience, and sees the goal of therapy as helping clients manage stress to regulate their brain and enhance neuroplasticity through attunement and addressing lifestyle factors like sleep and exercise.
Application of The Cognitive Psychology in Mental Illness or Traum.docxspoonerneddy
Application of The Cognitive Psychology in Mental Illness or Trauma
Melvin Coe
Capella University
Professor Theresa Crawford
Research Foundation of History Systems in Psych
June 7, 2020
Running Head: APPLICATION OF THE COGNITIVE PSYCHOLOGY 1
APPLICATION OF COGNITIVE PSYCHOLOGY 2
Application of The Cognitive Psychology in Mental Illness or Trauma
Introduction
In the present times, the number of people suffering from mental challenges has been on the rise. It is a time that demands psychologists to have better and effective scientific methods that would help them handle the different psychological issues being brought to their attention. Cognitive psychology is one of the scientific methods that can be used by psychologists to study the mind as an information processor. Using the method, psychologists are able to develop cognitive theories and models that would align and seems applicable in individual cases they are handling for instance, how one perceives, understands, remembers, attentiveness, makes use of language and is conscious of things.
The principal goals of clinical psychology are to generate knowledge based on scientifically valid evidence and to apply this knowledge to the optimal improvement of mental and behavioral health (Baker, McFall, Shoham, 2008). The values, principles, and methods of cognitive psychology and psychodynamic psychotherapy are anticipated to be utilized in an investigation which replaces maladaptive behaviors. The interest in the study is centered around increasing social response while decreasing maladaptive behaviors by utilizing differential reinforcement of alternative behaviors. Differential reinforcement of alternative behaviors is a procedure that reduces a problematic behavior by reinforcing an appropriate alternative behavior that serves the same function.
Research topic (Cognitive Psychology in the influences of patient with trauma or mental illness)
The research paper revolves around understanding how cognitive psychology influences patients with trauma and mental illness. It is evident that cognitive psychology revolves around the study of the process within the brain and they vary from learning, perception, attention, memory, thinking, language, attention and problem-solving (Maslow, 1943). The mental illness and trauma are a result of some of the brain processes thus with embracing the school of cognitive psychology it is easier to understand and comprehend the potential solutions. The problem of mental illness has become complaisant in the current era and with the limited resources and technology in the past made it a challenge to contain it but the advancement in field of psychology has made it easier to find solutions to the problem. There is no specific treatment for trauma or mental illness in this era of medical advancement and technology but cognitive psychology is making it easier to help under.
Application of The Cognitive Psychology in Mental Illness or Traum.docxssusera34210
Application of The Cognitive Psychology in Mental Illness or Trauma
Melvin Coe
Capella University
Professor Theresa Crawford
Research Foundation of History Systems in Psych
June 7, 2020
Running Head: APPLICATION OF THE COGNITIVE PSYCHOLOGY 1
APPLICATION OF COGNITIVE PSYCHOLOGY 2
Application of The Cognitive Psychology in Mental Illness or Trauma
Introduction
In the present times, the number of people suffering from mental challenges has been on the rise. It is a time that demands psychologists to have better and effective scientific methods that would help them handle the different psychological issues being brought to their attention. Cognitive psychology is one of the scientific methods that can be used by psychologists to study the mind as an information processor. Using the method, psychologists are able to develop cognitive theories and models that would align and seems applicable in individual cases they are handling for instance, how one perceives, understands, remembers, attentiveness, makes use of language and is conscious of things.
The principal goals of clinical psychology are to generate knowledge based on scientifically valid evidence and to apply this knowledge to the optimal improvement of mental and behavioral health (Baker, McFall, Shoham, 2008). The values, principles, and methods of cognitive psychology and psychodynamic psychotherapy are anticipated to be utilized in an investigation which replaces maladaptive behaviors. The interest in the study is centered around increasing social response while decreasing maladaptive behaviors by utilizing differential reinforcement of alternative behaviors. Differential reinforcement of alternative behaviors is a procedure that reduces a problematic behavior by reinforcing an appropriate alternative behavior that serves the same function.
Research topic (Cognitive Psychology in the influences of patient with trauma or mental illness)
The research paper revolves around understanding how cognitive psychology influences patients with trauma and mental illness. It is evident that cognitive psychology revolves around the study of the process within the brain and they vary from learning, perception, attention, memory, thinking, language, attention and problem-solving (Maslow, 1943). The mental illness and trauma are a result of some of the brain processes thus with embracing the school of cognitive psychology it is easier to understand and comprehend the potential solutions. The problem of mental illness has become complaisant in the current era and with the limited resources and technology in the past made it a challenge to contain it but the advancement in field of psychology has made it easier to find solutions to the problem. There is no specific treatment for trauma or mental illness in this era of medical advancement and technology but cognitive psychology is making it easier to help under.
This document proposes a new method for creating a physiological and anatomical brain map by associating specific brain areas and systems with the effects of various drugs, substances, and physiological conditions. The map would be created by combining the localized signals produced by different molecules, drugs, and pathophysiological states in the brain using imaging techniques. The authors argue this could provide a more comprehensive view of brain structure and function compared to existing brain mapping methods alone. They suggest this approach may help identify brain areas and systems not adequately addressed by current pharmaceutical treatments and provide more objective indicators of normal and abnormal brain states.
This document discusses the relationship between biological psychology and cognitive psychology. Biological psychology deals with brain functioning and how the brain influences behavior, while cognitive psychology focuses on mental processes like memory, problem-solving, and learning. Both fields contribute to understanding behavior and mental illnesses. The document outlines some of the main theories and contributors to biological psychology, like Lashley, and cognitive psychology, such as Hebb. It also describes how biological and cognitive approaches can be applied therapeutically.
Cognitive behaviour therapy aims to address addiction through four key areas: (1) Motivation and engagement, (2) Managing impulses and craving, (3) Mood management, and (4) Mindful recovery. CBT seeks to motivate change, teach skills to manage impulses to use substances, help manage negative emotions, and support mindful recovery approaches. Recent research also indicates cognitive control is impaired in addiction and CBT may need to directly target and rehabilitate neurocognitive functions to effectively treat addiction.
Introduction to the BioPsychoSocial approach to Addictionkavroom
In this 45 minute introductory lecture you will learn about the biopsychosocial approach to addiction
At the end of this session you should:
Have an understanding of the neurological systems that underpin addiction.
Appreciate that the ways addiction is explained has a direct influence upon treatment.
Be aware that there is no unified theory of addition, but that an integrated approach can help explain onset and maintenance of addictive behavior.
Cognitive behavior approach to psychopathologyPhi Lo
Cognitive behavioral therapy (CBT) is an effective treatment for psychopathology according to research. Meta-analyses show large effect sizes for CBT in treating various disorders like depression and anxiety. CBT is more cost-effective than medication and lowers relapse risk after treatment ends compared to antidepressants alone. While medication and CBT are both effective, combining the two may produce the best outcomes for severe depression.
Transformative Moments- Short Stories from the Biodynamic Psychotherapy Room Elya Steinberg
This document summarizes key aspects of biodynamic psychotherapy and massage. It discusses how the biodynamic therapist receives feedback from the client's autonomous nervous system, objective observations of the body, and the client's reported sensations to guide treatment in real-time. The therapist aims to support the client's self-healing abilities by responding attunedly to changes in both client and therapist. A case study of a client, "Lily", is discussed, whose various pains represented conflicts between different parts of herself not in communication. The therapist aims to understand such conflicts retained in the body and mind.
- Cognitive behavioral therapy (CBT) produces measurable changes in the brain similar to those produced by medications. Brain imaging studies show CBT decreases glucose metabolism in the obsessive compulsive disorder (OCD) brain to levels seen in healthy people, proportional to symptom improvement.
- Research has identified neurochemical and physiological events underlying psychotherapy's effects, such as the roles of oxytocin, arginine vasopressin, and NMDA in controlling attachment, empathy, and fear extinction. Genetic variations may predict who responds best to different psychotherapies. Integrating neurobiology with psychotherapy techniques holds promise to enhance treatment of mood and anxiety disorders.
Effects of StressProvide a 1-page description of a stressful .docxTatianaMajor22
Effects of Stress
Provide a 1-page description of a stressful event currently occurring in your life.
Discuss I am married work a full time job as an occupational therapy assistant am taking two courses
Have to take care of a home feed the animals attend to laundry
Think of my pateitns worry about their well being and what I can do for them ( I bring home my patients issues)
Constantly doing paper work for work such as documentation for billing
I feel like I have no free time for me some days I don’t even eat dinner or lunch because I don’t have time to make anything or am just too tired to cook
On top of this I am married and married ppl do argue and my husband am I have been bunting heads on finances.
Then, referring to information you learned throughout this course, address the following:
· What physiological changes occur in the brain due to the stress response?
· What emotional and cognitive effects might occur due to this stressful situation?
· Would the above changes (physiological, cognitive, or emotional) be any different if the same stress were being experienced by a person of the opposite sex or someone much older or younger than you?
· If the situation continues, how might your physical health be affected?
· What three behavioral strategies would you implement to reduce the effects of this stressor? Describe each strategy. Explain how each behavior could cause changes in brain physiology (e.g., exercise can raise serotonin levels).
· If you were encouraging an adult client to make the above changes, what ethical considerations would you have to keep in mind? How would you address those ethical considerations?
In addition to citing the online course and the text, you are also required to cite a minimum of four scholarly sources. For reputable web sources, look for .gov or .edu sites as opposed to .com sites. Please do not use Wikipedia.
Your paper should be double-spaced, in 12-point Times New Roman font, and with normal 1-inch margins; written in APA style; and free of typographical and grammatical errors. It should include a title page with a running head, an abstract, and a reference page.
The body of the paper should be at least 6 pages in length total
not including the reference or title page
Assignment 1 Grading Criteria
Maximum Points
Described a stressful event.
20
Explained the physiological changes that occur in the brain due to the stress response.
36
Explained the emotional and cognitive effects that may occur due to this stressful situation.
32
Analyzed potential differences in physiological, cognitive, and emotional responses in someone of a different age or sex.
32
Discussed the physical health risks.
28
Provided three behavioral strategies to reduce the effects of the stressor and explained how each could cause changes in brain physiology.
40
Analyzed ethical considerations in implementing behavioral strategies and offered suggestions for addressing these.
40
Integrated at least two scholarly references .
Transformative Moments- Short Stories from the Biodynamic Psychotherapy Room...Elya Steinberg
This article discusses biodynamic psychotherapy and biodynamic massage. It provides details on a case study of a client, Lily, who received biodynamic massage from a student, Roy. The massage involved working on different parts of Lily's body using various touch methods. In a discussion after the session, questions were raised about combining different touch methods. The author then analyzes Lily's case further, making assumptions about retained conflicts in her body and mind based on her reported pains and tensions in different areas. The author suggests Lily's shoulders may be bearing a burden that other parts of her body are not sharing, representing different parts of her that do not communicate.
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luisetto m et al mindset kinetics and some depression status a new quantitative model under biochemical - toxicology approach insights depress anxiety.2018,impact #PSYC,#neuro,#science,#tox,#go gle,HIGH,#cognitive, COLUMBIA UNIV. LIBRARY, SCILIT, WORLDCAT
1. Insights on the Depression and AnxietyOpen Access
HTTPS://WWW.HEIGHPUBS.ORG
029
Abstract
Depression: According Pubmed Health: Depression is a state of low mood and aversion to
activity that can affect a person’s thoughts, behavior, feelings and sense of well-being (moderate
or severe).
Can we consider some depression status due to high amount of some stressant stimulus? Or
continuous stress in a limited (or long) period? How can react mindset and brain in management
an high amount of negative stressing thinking? Observing some relevant literature also mindset
kinetics must be considered to better classify this kind of disorder under a specific endogenous
–exogenous biochemical-toxicological aspect.
Concept like Kinetics, reaction velocity limits, saturation of the systems, residual buffer
properties are currently used in biochemistry and related discipline.
This concepts can be applied also in some depression condition to better explain some
phenomena?
Research Article
Mindset kinetics and some depression
status: A new quantitative model
under biochemical - toxicology
approach?
Luisetto M1
*, Ghulam Rasool Mashori2
, Behzad Nili-
Ahmadabadi3
, Farhan Ahmad Khan4
and Kausar Rehman Khan5
1
Applied Pharmacologist, Independent Researcher, Italy
2
Pharm D, PhD in Clinical Pharmacology, Full Professor & Director, Department of Pharmacology,
Medical & Health Sciences for Woman, Peoples University of Medical and Health Sciences for
Women, Pakistan
3
Pharm D/PhD Innovative Pharmaceutical Product Development Specialist, USA
4
Professor & Head, Department of Pharmacology, ESIC Medical College and Hospital (Ministry
of Labour and Employment, Govt. of India), India
5
Preston University Karachi, Pakistan
*Address for Correspondence: Luisetto M,
Applied Pharmacologist, Independent Researcher,
Italy, Email: maurolu65@gmail.com
Submitted: 12 July 2018
Approved: 23 July 2018
Published: 24 July 2018
Copyright: 2018 Luisetto M, et al. This is
an open access article distributed under the
Creative Commons Attribution License, which
permits unrestricted use, distribution, and
reproduction in any medium, provided the
original work is properly cited.
Keywords: Depression; Mindset kinetics;
Toxicology; Theory of constraints; Mindfulness;
Neuroscience; Biochemistry
How to cite this article: Luisetto M, Mashori GR, Nili-Ahmadabadi B, Khan FA, Khan KR. Mindset kinetics
and some depression status: A new quantitative model under biochemical - toxicology approach?
Insights Depress Anxiety. 2018; 2: 029-039. https://doi.org/10.29328/journal.ida.1001008
Introduction
Depression is one of the most prevalent and debilitating of the neuro- psychiatric
disorders. According many Studies cognitive therapy is as ef icacious as antidepressant
medications at treating depression, and it seems to reduce the risk of relapse even after
its discontinuation. Cognitive-behavioral therapy and antidepressant drugs probably
engage some similar neural mechanisms, as well as mechanisms that are distinctive to
each. A better speci ication and knowledge and of these mechanisms might to be used to
guide therapy selection and to improve clinical outcomes. Today great enphasys concern
the neuro transmitter’s status and its implication as main pharmacological strategy.
But are we sure that is the only point of view to consider in this kind of disorder?
Starting from the effective ef icacy level of actual pharmacological therapy and the
number of relapses in some patients is relevant to observe this disorder under a new
light (the same also ef icacy of some non-pharmacological therapy).
2. Mindset kinetics and some depression status: A new quantitative model under biochemical - toxicology approach?
Published: July 24, 2018 030
This work is produced starting from a medicinal chemistry and biochemistry
approach (kinetics) related to some endogenous or exogenous noxa that can produce
unbalances of brain-mind. Every biological system present a determinate limit and
also brain-mind systems: an over stimulation of stressant stimulous for long time or
in acute can produce great effect in more receptive subject. Single individual resilience
ability and residual biochemical buffer systems can help in balance the system.
Theory of depression consider in example etiopathogenetic (genetic, biochemistry),
psycoanalitic factors and other that contribute to the global status of a subject.
Depression conditions can be compared to a psychological manifestation of the
spirit which although has been in luenced by hormonal level and many other biological
factors however has really only relationship with hormones or neurotransmitters? Are
this the only factors involved?
In example drinking coffee you would become stressed and angry but anger is a
product of someone’s provoking you, it has nothing to do with coffee for caffeine. Even
if this substatia can enhance global reactivity.
Yes losing hope is slowing down someone’s daily activity but this is only related to
the serotonin level?
In other example: pain is related to the endorphin level but pain in example
product of the deposit of crystals in the joints, could be a pressure on trigeminal or
sciatic nerve: therefore pain is not a product of endorphin level itself but a secondary
effect of Pathologic moves. Therefore manipulating serotonin and messing up with so
many nervous circuits must cause new disorder which we call them side effects (In ex
serotoninergic syndrome).
Neurotransmittermanipulationlikeinanxietyandantipsychoticandantidepressant
drugs have been introduced after 70s, and the psychomedical community and giant
Pharma and guaranteeing their income is trying to pathologize day after day some in
our opinion natural behavioral process of the spirit. So Tomorrow happiness could
be considered as disorder? And as well as yesterday too much energy of children was
considered not physiologic? Today some prestigious healthcare institution is talking
about also a pregnancy mood disorder? It is ridiculous. Why the medical community is
trying to pathologize everything in next time?
Is universally known that many psycologic or behavior discipline can help unman
being in correctly manage stressant stimulus (mindfulness, yoga and many other
discipline). In all this discipline we observe in example great inside concentration
activity excluding external stressant stimulus. So depression can be considered more
related to quality of thinking or to the amount of negative thinking (and related time
involved)?
Why the time can help some people to be more resilient after negative stressant
stimulus?
Observing other scienti ic discipline in example the light properties in physics
discipline: it can be considered under double condition: As ondulatory properties or as
particle (and every properties veri ied esperimentally).
(In example see the quantum theory in chemical physics): 2 different point of view
of the same phenomena (Figures 1,2).
So can we think some mindset-brain process under multiple aspect phenomena?
Thinking but also amount of thinking and the global quality of thinking (positive or
not) is a relevant factor to better understand mindset status. And is very interesting
3. Mindset kinetics and some depression status: A new quantitative model under biochemical - toxicology approach?
Published: July 24, 2018 031
observe if the brain show limits to manage this stressant conditions? The kinetics of
this phenomena can help us to better clear some psycologic- psychiatric, neurlogic
condition? A global saturation of the system, in example due by high stimulous as
today we see in modern world, can contribute to the ef iciency of the systems? And
what can be the effect in a saturated system to sostitute negative stress with positive?
In order to correctly evaluate the global system the negative-positive stress
balances must be compared in example to a receptorial model with agonist antagonist
in competition (pharmacological molecules) and observe the effect when positive
stimulus increase related the amount of negative (Figure 3).
And to correctly set the problem is useful to weigh stressant negative stimulus to
correctly evaluate a physio-pathologic condition?
Why2centuriesagoinmedicaltextbookstherewasn’tdescribedansiaaspathology?
Some psycologic- psychiatric condition changed in last centuries in medical and social
approach?
Contribute to this phenomena high amount of new stressant agents? (Media,
internet, civilization, business conditions et other recent conditions).
After high stressant periods a download of metabolic - neurotransmitters and other
molecule is a natural pathway? Is a conservative strategies? It can be compared to an
ibernant metabolic process in some animals?
Figure 1: Corpuscular and ondulatory theory of light.
Figure 2: Quantum theory, orbital energy, quantized energy level (not linear but quantized).
Figure 3: An antagonist molecule can bind to the receptor avoiding the agonist link.
4. Mindset kinetics and some depression status: A new quantitative model under biochemical - toxicology approach?
Published: July 24, 2018 032
Material and Methods
With an observational approach and analyzing scienti ic literature from biomedical
databases (PubMed and other like university library database) we try to verify if
mindset kinetics pro ile can in luence the depressive tract. Then we try to produce an
experimental tests hypotesys to verify the buffer properties of brain-mind and kinetics
involved in some brain- mind phenomena.
Mindset kinetics is also deeply involved in many kind of thinking and abilities
or behavior like: Catastrophic thinking, extreme thinking, Mental traps, too rapid
conclusion approach, con lict management, Emotion management, positive vision,
personal Goal setting, isolation, to search help ability and resilience, self-esteem and
self-motivation, critical thinking approach, Love our self-ability.
And also other like: ability to Change the frame of the situation in complex situations,
Rethinking the problems, Mental training, change negative thinking with pleasure
activity, Stress management (coping strategy), Living and thinking at the present
moment(not in past or in future), Emotional indifference and intelligence, Forgives
ability, Contemplation exercise (mindfulness) to reduce stressing situations, No guilt
sense (to make more free your mind and thinking), Dream up (to brake the negative
thinking), Make more umor in the dif iculties, Take distance from your negative thinking
(mindfulness),Verify our sense attribution to the stressant situation, Open to new
experiences, social intelligence, Neophyte behavior, Learn new experience (positive),
Use better the opportunities, No fear for new situation).
Results
From literature
According article mindset kinetics under a toxicological aspect “in order to evaluate
stressing situation are fundamental: kind of stress (in example HIGHor not); amount of
global stressing condition, simultaneous;
Duration of stimulus (cronic conditions?) individual status (resilience? stress
management ability, depression) psycologic but also genetic; kinetics.” [1] and in
article Attitudes and skills in business working setting : a HR management tool 2017: “
ability to Treat great problem in a simply way. Learning by the errors, lifelong learning,
Root causes analysis procedure (you can make errors but what is crucial is your ability
to rise on), Delegate more, Time management (to do list and other management
instruments), give priority, Rethinking the great problems, searching help in every
situation, zero thinking ability, take your time ability to give response.
Change the frame of the situation. Mental training, no extreme thinking, lose comfort
zone. Orientation attitudes (to be oriented in all situation), what your goal, what your task,
what resource you need to do better a works (resource, help, instruments, strategies)
to say no ability negotiation, con lict management, Positive thinking, Not catastrophic
thinking,Nonegativityinworkingsettings,Nottothinktobeatthecenteroftheworld,Pay
attention to Mental traps, no rapid conclusion, No preconception, Think to your positive
things happened in the day, Hard works to have more results help in work dif iculties,
Stop negative thinking with pleasure activity, Thinking Oriented to solution not only to
problems, Positive results drive towards more self-motivation, Use Entertainments as
motivational force, No mental traps, No mental limits, Trust in your instinct” [2].
“Stress Management and Coping Strategy Mindfulness: Living and thinking at the
present moment (not past or future) (Constantly thinking to troubles make the mind
weaker). Stop thinking (for 6 seconds), take a pause form trouble, Stop to the judgment,
Emotional indifference, Forgives ability (mindfulness), No intrusive thinking, Changing
sense of situation, Context, Make one think on the same time, learn go slowly, no
multitasking Meditation technique is one hobby. Give value to the others, listen the
5. Mindset kinetics and some depression status: A new quantitative model under biochemical - toxicology approach?
Published: July 24, 2018 033
other thinking in the right way. Contemplation (mindfulness) is to reduce stress. No guilt
sense (to make freer your mind). Massages, stretching, Sports, music, arts are hobbies.
Holidays are to reduce stress. Dream up (to break negative thinking). Laugh, sense of
humor, minimize, and leave drift the problems. Make humor in the dif iculties. Stop the
working connections when you are not at work or in of ice (if possible). Remember
that life is also out of of ice (family, friends, social). Build positive relationship (friends,
family and other). Learn to forgive mobbing management, to search emotional support
ability, Attention to the distortion in, communication (up, down and between), Hear
but not Listen (think before to the real sense of what other says to you), Pay attention
to informal notice about you and to the your images other see. Take distance from your
thinking (mindfulness), Verify our sense attribution to the situation, No too much rapid
response, Say you’re thinking with calm, No anger explosion, Open to new experiences,
Neophyte behavior, Learn some new experience (positive), Use well the opportunities,
No fear for the new situation, Make Glide the situation, To complain frequently results
in negative cycle, Search social support, family, friends, Searching fellow, alliances,
Rapidly stop the cause of trouble, before they increase(kill the monster before it
increase), Take time to give response (time to correctly think to the solution), Deep
knowledge in mobbing preventing activity (normative, law, of ice, strategies), Request
of write order about strange request, Register every strange situation, Send write letter
to chief of icer and to chief UR Manager of ice, Pay attention to your body, emotional
energy level, rest, Coaching supportive use” [2].
According Erin P Gillung et al., “Major depressive disorder (MDD) is the leading
cause of disability in the developed world, yet broadly effective treatments remain
elusive. Up to 40% of patients with depression are unresponsive to at least two
trials of antidepressant medication and thus have “treatment-resistant depression”
(TRD). There is an urgent need for cost-effective, non-pharmacologic, evidence-based
treatments for TRD. Mindfulness-Based Cognitive Therapy (MBCT) is an effective
treatment for relapse prevention and residual depression in major depression, but
has not been previously studied in patients with TRD in a large randomized trial” [3].
According article A NEW PHYSIO-ANATOMIC BRAIN MAP 2017 “Why many area and
brain systems are interested by pharmaceutical industry activity and other no?
The same we can think a new method to measure brain status observing some
individual characteristics as:
All this indicators can be added to create a single data to verify a normal status
giving more objectivity. Is not a new procedure but we think is innovative is to create
a complexive map using this information. This approach can be useful in some ield as
forensic science, jurisdictional settings, HR management, and many other (Emotional
Systems). Depression level, anxious status, schizophrenia, emotional status, or other
pathological condition as Parkinson, coma, epileptic status, exiting status, dementia,
migraine, sleep pro ile, hormonal status. And all other brain condition. Using for
example statistical analysis methods in order to not have a relative condition that
modify according the society evolution level but a more objectivable parameter to
use in stabile way (nor relative). (What cells involved and related intensity of signal
and objectivable effect). Information that come from directly from the cell or systems
involved. We can have a physiology and anatomic information complete related whit
the ef icacy of some drugs or substances. This approach start from observing some
brain disease (or systemic) and the effect due by some iatrogenic or toxic substanties
and the drugs (used in therapy).
All this condition are often under pharmacological therapies and the related
receptor pro ile. (The same we can consider the pro ile of addict’s substanties and
related receptor). We can see that in many situation we have an abuse or misuse of
some psychotropic drugs also in young people and this phenomena is growing every
year. Have we a single indicator to verify a normal or abnormal brain status? or we are
6. Mindset kinetics and some depression status: A new quantitative model under biochemical - toxicology approach?
Published: July 24, 2018 034
obliged to live in a psychological status managed by pharmacological molecules? “[4].
Dean J et al. written: “Major Depressive Disorder (MDD) is one of the most common and
debilitating mental disorders; however, its etiology remains unclear. This paper aims
to summarize the major neurobiological underpinnings of depression, synthesizing the
indingsintoacomprehensiveintegratedview.Aliteraturereviewwasconductedusing
Pubmed. Search terms included “depression” or “MDD” AND “biology”, “neurobiology”,
“in lammation”, “neurogenesis”, “monoamine”, and “stress”. Articles from 1995 to
2016 were reviewed with a focus on the connection between different biological and
psychological models. Some possible pathophysiological mechanisms of depression
include altered neurotransmission, HPA axis abnormalities involved in chronic
stress, in lammation, reduced neuroplasticity, and network dysfunction. All of these
proposed mechanisms are integrally related and interact bidirectionally. In addition,
psychological factors have been shown to have a direct effect on neurodevelopment,
causing a biological predisposition to depression, while biological factors can lead to
psychological pathology as well. The authors suggest that while it is possible that there
are several different endophenotypes of depression with distinct pathophysiological
mechanisms, it may be helpful to think of depression as one united syndrome, in which
these mechanisms interact as nodes in a matrix. Depressive disorders are considered
in the context of the RDoC paradigm, identifying the pathological mechanisms at every
translational level, with a focus on how these mechanisms interact. Finally, future
directions of research are identi ied” [5].
Shin YC: “Various types of stress affect mental health in the form of mood disorders,
anxiety disorders, and suicidal ideation. Recently, the increasing suicide rate in the
working-age population has become a major mental health concern in Korea. Thus, we
investigated what kind of stress in luence depression, anxiety, and suicidal ideation
in Korean employees. The study participants were 189,965 employees who attended
health screenings and responded to the Center for Epidemiologic Study-Depression
Scale, the Beck Anxiety Inventory, and a questionnaire on the major causes of stress
and suicidal ideation. We investigated the major causes of stress by gender and age
categories and used binary logistic regression to determine the impact of the causes
of stress on depression, anxiety and suicidal ideation. Of several stress causes, work-
related stress was the most prevalent, regardless of age category and gender, followed
by interpersonal relationships. However, interpersonal relationships and inancial
problems were the predominant causes of stress related to depression or suicidal
ideation. This research suggests that despite the fact that work is the most common
cause of stress for Korean employees, stress related to life problems other than work
has a greater in luence on the mental health of Korean employees” [6].
According Harvey et al., “The purpose of the present study was to address 1)
whether exercise provides protection against new-onset depression and anxiety
and 2) if so, the intensity and amount of exercise required to gain protection and,
lastly, 3) the mechanisms that underlie any association. A “healthy” cohort of 33,908
adults, selected on the basis of having no symptoms of common mental disorder or
limiting physical health conditions, was prospectively followed for 11 years. Validated
measures of exercise, depression, anxiety, and a range of potential confounding and
mediating factors were collected. Undertaking regular leisure-time exercise was
associated with reduced incidence of future depression but not anxiety. The majority
of this protective effect occurred at low levels of exercise and was observed regardless
of intensity. After adjustment for confounders, the population attributable fraction
suggests that, assuming the relationship is causal, 12% of future cases of depression
could have been prevented if all participants had engaged in at least 1 hour of physical
activity each week. The social and physical health bene its of exercise explained a
small proportion of the protective effect. Previously proposed biological mechanisms,
such as alterations in parasympathetic vagal tone, did not appear to have a role in
explaining the protection against depression. Regular leisure-time exercise of any
7. Mindset kinetics and some depression status: A new quantitative model under biochemical - toxicology approach?
Published: July 24, 2018 035
intensity provides protection against future depression but not anxiety. Relatively
modest changes in population levels of exercise may have important public mental
health bene its and prevent a substantial number of new cases of depression” [7].
Prathikanti S et al., “Conventional pharmacotherapies and psychotherapies for
major depression are associated with limited adherence to care and relatively low
remission rates. Yoga may offer an alternative treatment option, but rigorous studies
are few. This randomized controlled trial with blinded outcome assessors examined
an 8-week hatha yoga intervention as mono-therapy for mild-to-moderate major
depression. Investigators recruited 38 adults in San Francisco meeting criteria for
major depression of mild-to-moderate severity, per structured psychiatric interview
and scores of 14-28 on Beck Depression Inventory-II (BDI). At screening, individuals
engaged in psychotherapy, antidepressant pharmacotherapy, herbal or nutraceutical
mood therapies, or mind-body practices were excluded. Participants were 68% female,
with mean age 43.4 years (SD = 14.8, range = 22-72), and mean BDI score 22.4 (SD = 4.5).
Twenty participants were randomized to 90-minute hatha yoga practice groups twice
weekly for 8 weeks. Eighteen participants were randomized to 90-minute attention
control education groups twice weekly for 8 weeks. Certi ied yoga instructors delivered
both interventions at a university clinic. Primary outcome was depression severity,
measured by BDI scores every 2 weeks from baseline to 8 weeks. Secondary outcomes
were self-ef icacy and self-esteem, measured by scores on the General Self-Ef icacy
Scale (GSES) and Rosenberg Self-Esteem Scale (RSES) at baseline and at 8 weeks.
In intent-to-treat analysis, yoga participants exhibited signi icantly greater 8-week
decline in BDI scores than controls (p-value = 0.034). In sub-analyses of participants
completing inal 8-week measures, yoga participants were more likely to achieve
remission, de ined per inal BDI score ≤ 9 (p-value = 0.018). Effect size of yoga in reducing
BDI scores was large, per Cohen’s d = -0.96 [95%CI, -1.81 to -0.12]. Intervention groups
did not differ signi icantly in 8-week change scores for either the GSES or RSES. In adults
with mild-to-moderate major depression, an 8-week hatha yoga intervention resulted in
statistically and clinically signi icant reductions in depression severity [8].
Piotr Gałecki et al., “Separating emotions from cognition seems an impossible task in
a human being’s everyday experiences, similarly to the functional separation of frontal
lobes and hippocampal formations. The majority of emotional experiences are linked
with cognitive processes, and emotions are an indispensable element of cognition (the
so-called principle of cognition compatibility with mood). This principle affects not
only memory processes but also includes perception, attention, or linguistic abilities.
It seems that the so-called “reptilian brain” is in charge of steering our choices, while
“rational” frontal lobes are always one step behind. The pace of evolutionary changes
does not keep up with the intensity of civilization changes. Therefore, symptoms of
depression may be one of the forms of adaptation to excessively high requirements
of the environment. When summing up our deliberations regarding the etiology of
depression, can we simply claim that Nature has not inished its work? We will leave
this question without an answer” [9].
Ferrarifetal.,“Depressivedisordersareheterogeneousdiseases,andthecomplexity
of symptoms has led to the formulation of several aethiopathological hypotheses.
This heterogeneity may account for the following open issues about antidepressant
therapy: (i) antidepressants show a time lag between pharmacological effects, within
hours from acute drug administration, and therapeutic effects, within two-four
weeks of subchronic treatment; (ii) this latency interval is critical for the patient
because of the possible further mood worsening that may result in suicide attempts
for the seemingly ineffective therapy and for the apparent adverse effects; (iii) and
only 60-70 % of treated patients successfully respond to therapy. In this review, the
complexity of the biological theories that try to explain the molecular mechanisms of
these diseases is considered, encompassing (i) the classic “monoaminergic hypothesis”
8. Mindset kinetics and some depression status: A new quantitative model under biochemical - toxicology approach?
Published: July 24, 2018 036
alongside the updated hypothesis according to which long-term therapeutical action of
antidepressants is mediated by intracellular signal transduction pathways and (ii) the
hypothalamic-pituitary-adrenal axis involvement. Although these models have guided
research efforts in the ield for decades, they have not generated a compelling and
conclusive model either for depression pathophysiology or for antidepressant drugs’
action. So, other emerging theories are discussed: (iii) the alterations of neuroplasticity
and neurotrophins in selective vulnerable cerebral areas; (iv) the involvement of
in lammatoryprocesses;(v)andthealterationsinmitochondrialfunctionandneuronal
bioenergetics. The focus is put on the molecular and theoretical links between all
these hypotheses, which are not mutually exclusive but otherwise tightly correlated,
giving an integrated and comprehensive overview of the neurobiology of depressive
disorders” [10].
According Forsyth et al “The purpose of this article is to describe changes in positive
and negative thinking in adult inpatients with depression who attended an Advanced
Practice Nurse-led Cognitive Behavioral Therapy group on 1 inpatient unit in a large
medical center.
A descriptive design with a retrospective cohort chart review was conducted (n
= 427). Positive and negative thinking were measured by the Automatic Thoughts
Questionnaire at admission and at discharge.
Apairedt-testrevealedasigni icantchange(p=0.001)inbothpositiveandnegative
thinking in the desired direction between admission and discharge. It is important to
measure clinical improvements” [11].
Trick L et al., “Depression is common in people with long term conditions, and
is associated with worse medical outcomes. Previous research shows perseverative
negative thinking (e.g. worry, rumination) predicts subsequent depression and worse
medical outcomes, suggesting interventions targeting perseverative negative thinking
could improve depression and medical outcomes. Previous studies recruited healthy
individuals, however. This review aimed to determine the temporal relationship and
strength of prospective association of perseverative negative thinking with depression,
anxiety and emotional distress in people with long term conditions.
Four electronic databases were searched for studies including standardised measures
of perseverative negative thinking and depression, anxiety or emotional distress, and
which presented prospective associations. Findings were narratively synthesized.
Thirtystudieswereidenti iedinarangeoflongtermconditions.Perseverativenegative
thinking and subsequent depression, anxiety or emotional distress were signi icantly
correlated in the majority of studies (bivariate r=0.23 to r=0.73). 25 studies controlled
for confounders, and in 15 perseverative negative thinking predicted subsequent
depression, anxiety or emotional distress. Results varied according to condition and
study quality. Six of 7 studies found bivariate associations between depression, anxiety
or emotional distress and subsequent perseverative negative thinking, though 2 studies
controlling for key covariates found no association. Few studies assessed the impact of
perseverative negative thinking on medical outcomes.
Strongest evidence supported perseverative negative thinking predicting subsequent
depression, anxiety and emotional distress in people with long term conditions. Further
prospective research is warranted to clarify the association of perseverative negative
thinking with subsequent poor medical outcomes” [12].
And Saori Nishikawa et al written: “Previous studies have demonstrated an
association between negative life events (NLEs) in childhood and resilience/
posttraumatic growth (PTG) with regard to the pathogenesis of major depressive
disorder. We hypothesized that the type and timing of NLEs interact to in luence
9. Mindset kinetics and some depression status: A new quantitative model under biochemical - toxicology approach?
Published: July 24, 2018 037
mental health in the general youth population. Therefore, the present study aimed to
examine the effects of NLE timing and intensity on current depressive symptoms, and
to determine the direct and indirect effects of NLEs/resilience on PTG and depression
among non-clinical adolescents. Data were collected from 1,038 high-school students
across seven high schools in Fukui, Japan, during their freshman and sophomore years
(648 boys and 390 girls, mean age = 15.71, SD = 0.524). Respondents completed a set
of questionnaires designed to evaluate the type and timing of NLEs, depressive and
traumatic symptoms, and PTG. Cluster analysis was used to divide participants into
three groups based on outcomes: “cluster 1” (n = 631), for whom depressive scores
were signi icantly lower than other two subgroups (p < 0.05, for both); “cluster 2”
(n = 52), for whom levels of current and past perceived stress associated with NLEs
were signi icantly higher than those of the other two subgroups (p < 0.05, for both);
“cluster 3” (n = 374), for whom perceived stress at the time of NLE was signi icantly
higher than that of participants in the cluster 1 (p < 0.05) group, but not the cluster
2 group. Our indings indicated that exposure to NLEs at a younger age resulted in
stronger negative outcomes and that NLE timing and intensity were associated with
PTG and current symptoms of depression. Furthermore, path analysis demonstrated
that associations between perceived stress at the time of NLEs were direct and indirect
predictors of current depression via PTG and that posttraumatic stress symptom and
PTG mediate the association between NLEs/trait-resiliency and current depression. In
conclusion, our indings suggest that event intensity, NLE timing, and gender may play
a role in emotional vulnerability during adolescence” [13].
Discussion
Related the literature observed is relevant to introduce new more objective way to
the de inition of depression status to be pharmacologically treated to be separated to
the subject that take advantages with other non-pharmacological strategies.
In this kind of disorder also mindset kinetics and their speci ic limits must be
considered to evaluate in objective way saturation situation of the system, speci ic
buffer properties and resilience abilities of individuals.
In actual scenario a better objective way to verify the amount of stressing condition,
time of exposure and quality must be introduced.
An useful instruments for healthcare professionals and patients.(using also a
toxicological approach: what toxic condition, amount and time of exposure and under
a biochemical aspect( kinetics, max velocity of a system, saturation) and not only the
receptorial status.
Observing biochemistry kinetics law can we think that a Zero Order Kinetics in
mindset kinetics can reduce some mind-brain disorder? (Only a determinate quantum
of stressing condition in a de inite amount of time) (Figures 4-6).
Conclusion
Scientist like Max Planck, Einstein, Bohr, de Broglie, Schrödinger, Heisenberg
et others (involved in theory of quantum chemical physic), E. goldratt (Teory of
constraints), Michaelis-Menten (kinetics theory), other biochemical and enzymatic
reaction theory must be deeply investigated also in other ields like neuroscience and
applied in order to better clear some process (Figure 7).
The factor that can join the organic theories to the psychological approach can be
an abnormal- pathological mindset kinetics process or an overuse or saturation in
some Psyco- neurologic process.
The single resilience ability or single buffer properties in biochemical receptorial
status must be also objectivable.
10. Mindset kinetics and some depression status: A new quantitative model under biochemical - toxicology approach?
Published: July 24, 2018 038
Figure 4: Example of zero order kinetic.
Figure 5: Saturation kinetc.
MINDSET BUFFER
NEGATIVE STRESS compe on POSITIVE STRESS
Figure 6: Mindset buffer model.
Figure 7: E. Goldratt: theory of constraints. Weakest ring.
So Is crucial to verify in more objective way the global amount of stressan
stimulous, time long (acute or prolonged time), quality of stressant condition and the
single resilience ablities as well as the buffer biochemical properties and other factors
that can be involved (environment, social situation, working condition, health status).
So it is real crucial to introduce new diagnostic objective tests to verify this
conditions.
11. Mindset kinetics and some depression status: A new quantitative model under biochemical - toxicology approach?
Published: July 24, 2018 039
Considering the stress antstimolus like an endogenous- exogenous toxic condition
factor can be interesting to think to new kind of Remedies.
A Toxicology status can be considered also a overuse of a system that can produce
great unbalances in physiology in some apparatus.
Clarifications
This paper was not written for any diagnostic or therapeutic intent, only to produce
new research hypotesys.
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