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Definitely, maybe:
       Implicit cognitive processes in
                  the clinic.
                            Frank Ryan
Clinical Psychologist                    Honorary Research Fellow
CNWL NHS Foundation Trust                Birkbeck College


                             London




                    f.ryan@psychology.bbk.ac.uk
Overview


• Implicit cognitive processes are plausible
  mechanisms to account for involuntary aspects
  of addiction
• These are potential targets for direct or indirect
  modification but component processes (e.g. goal
  maintenance) operate in existing treatments
• Addressing these processes has the potential to
  enhance outcomes
Time for CHANGE
•   Change
•   Habits
•   And
•   Negative
•   Generation of
•   Emotion
(Ryan, 2006)




                    f.ryan@psychology.bbk.ac.uk
Definitely! Maybe?
Should be doing ( good          Could be doing (plausible in
  evidence both laboratory        laboratory & indicative
  & clinic)                       trials)

• Focus on addictive habits     • Cognitive bias reversal
                                  (attentional bias reversal;
• Contingency management
                                  targeting automatic approach
• Encouraging attendance at
                                  tendencies; implicit challenges
  self-help “recovery” groups
                                  or behavioural experiments)
• Behavioural Couples Therapy
                                • Mindfulness practice
                                • Trans Cranial Brain
                                  Stimulation
An Appraisal Model of Cue Reactivity (Ryan, 2002)
  (arrows indicate influence of cognitive biases which can be facilitative or
                                  inhibitory)


                        Schematically Encoded Information
                          about self and addiction in LTM


                              Cognitions e.g.
    Cognitive                 Expectancies
    Appraisal:
                                                              Experience
                            Action Tendencies
    Stimulus
                                                                 of
                            and Behaviour
   encoded as
                                                               Craving
    drug cue                  Physiological
                                Reactivity



                                f.ryan@psychology.bbk.ac.uk
Adapted from Eysenck,1997
Cycle of pre-occupation

        Attribution of
     incentive salience


       Attentional bias

       Contents of
       Working memory




       Attentional bias




     f.ryan@psychology.bbk.ac.uk
A year is a long time in cognitive neuroscience…

• fMRI : appetitive cues detected at 33ms Childress et al
  2008

• Subliminal priming: 17 ms masked prime can lead to
  processing bias of smoking cues (Leventhal et al 2008)

• Stimuli stored in WM automatically attract attention (Soto
  et al 2008)




                     f.ryan@psychology.bbk.ac.uk
Basic Assumptions

• Impairment of executive control due to cognitive
  processing biases, poor goal maintenance, error
  detection and compromised decision making.
• These cognitive processes can be vulnerability factors
  for relapse.
• These are also potential targets for direct or indirect
  modification and can index therapeutic gain.
(Ryan, (2006)




                     f.ryan@psychology.bbk.ac.uk
The “Gateway” and the “Desktop”

Working memory <STM+Attentional control>
• Maintains representations of external stimuli
• Stores action plans
• Goal representations
• Task relevant information
NB:Even when goal maintenance fails in WM, goal
  is still retrievable from LTM !
Kane, MJ & Engle RW (2003) Working memory capacity and the control of attention: The contribution of goal
    neglect, response competition, and task set to Stroop interference. J Exptl Psych:(Gen) 132. 47-70



                                      f.ryan@psychology.bbk.ac.uk
Three Executive Functions

• Shifting (e. g . Switching from addition to subtraction-or from
   addiction to sobriety ?)

• Updating (Monitoring progress, keeping track or goal
   maintenance- or “I am not going to use today” ?)
• Inhibition (suppressing pre-potent responses e.g. Stroop task or
   anti-saccade task or “I will not dwell on my thoughts about drinking”)


   Miyake et al (2000) The unity and diversity of executive functions and their contributions to complex
   “frontal lobe” tasks: A latent variable analysis.
   Cognitive Psychology 41. 49-100.




                                      f.ryan@psychology.bbk.ac.uk
Motivational Enhancement

• Ambivalence is seen as conflict between controlled and
  automatic processes rather than a “balance sheet”

• Focus on decision making and goal specification is
  consistent with recruiting working memory processes
  and exerting a “top-down” regulation.




                    f.ryan@psychology.bbk.ac.uk
Therapeutic strategies with potential for increasing
                 cognitive control
•   Goal specificity
•   Stimulus Control: know those
    triggers
•   Implementation intentions
•   Be aware of and attempt to correct
    cognitive biases
•   Identify alternative rewards/goals
•   Self-monitoring
•   Distance /de- centre / mindfulness
    meditation
•   Challenge expectancies and
    implicit cognitions via behavioural
    experiments
•   Support self-efficacy

                             f.ryan@psychology.bbk.ac.uk
Implementing intentions to change

• If situation X occurs at time Y I will perform behaviour Z
  e.g.

“If I have money when I get paid on Friday I will do my
    shopping before visiting the cocaine dealer”

 “If I am offered alcohol to drink at the party I will say no
    thanks, but I would love a mineral water”.



Prestwich et al ( in Wiers & Stacy, 2006)


                                            f.ryan@psychology.bbk.ac.uk
Summary

• In the context of addiction, attentional bias prioritises cue
  detection and infiltration of working memory in a
  reciprocal way.

• This compromises executive control.

• If therapeutic intervention can increase cognitive control
  (e.g. by capturing WM resources) it is likely to reduce
  preoccupation with salient cues and attendant cue
  reactivity.


                      f.ryan@psychology.bbk.ac.uk
“The Road to recovery…is paved with good
                   rehearsals.”

• Enhanced outcome in addiction requires changes in both
  controlled and automatic processing
• Automatic processes, previously overlooked, can be
  reversed through practice and pre-empted by a range of
  techniques relying on goal maintenance and cognitive
  control.
• “Tried & tested” interventions need to delineate and
  accentuate the role of implicit cognitive processes.
• Emerging cognitive bias reversal technologies need to
  be evaluated and developed for further use.
• To maximise efficiency these need to be easily available.
                     f.ryan@psychology.bbk.ac.uk
Selected References

Childress, A R et al (2008) Prelude to passion: Limbic activation by “unseen” drug and
    sexual cues. ( click to view)

Leventhal, A.M.et al (2008). Subliminal processing of smoking related and affective cues
   in tobacco addiction. Experimental and Clinical Psychopharmacology. 4. 301-312

Ryan, F. (2002) Detected, Selected and Sometimes Neglected: Cognitive processing of
   cues in addiction. Experimental and Clinical Psychopharmacology. 10. 67-76.

Ryan, F. (2006) Appetite Lost and Found : Cognitive Psychology in the Addiction Clinic.
   In Cognition and Addiction. Munafo, M. & Albery, I. (Eds) OUP

Soto, D. et al. (2008) Automatic Guidance of Attention by Working Memory. Trends in
   Cognitive Sciences 342-348

Wiers, W.W., & Stacy, A.W. (2006) Handbook of implicit cognition and addiction.(Eds)
   Sage. London.



                               f.ryan@psychology.bbk.ac.uk

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Implicit cognitive processes in the addiction clinic

  • 1. Definitely, maybe: Implicit cognitive processes in the clinic. Frank Ryan Clinical Psychologist Honorary Research Fellow CNWL NHS Foundation Trust Birkbeck College London f.ryan@psychology.bbk.ac.uk
  • 2. Overview • Implicit cognitive processes are plausible mechanisms to account for involuntary aspects of addiction • These are potential targets for direct or indirect modification but component processes (e.g. goal maintenance) operate in existing treatments • Addressing these processes has the potential to enhance outcomes
  • 3. Time for CHANGE • Change • Habits • And • Negative • Generation of • Emotion (Ryan, 2006) f.ryan@psychology.bbk.ac.uk
  • 4. Definitely! Maybe? Should be doing ( good Could be doing (plausible in evidence both laboratory laboratory & indicative & clinic) trials) • Focus on addictive habits • Cognitive bias reversal (attentional bias reversal; • Contingency management targeting automatic approach • Encouraging attendance at tendencies; implicit challenges self-help “recovery” groups or behavioural experiments) • Behavioural Couples Therapy • Mindfulness practice • Trans Cranial Brain Stimulation
  • 5. An Appraisal Model of Cue Reactivity (Ryan, 2002) (arrows indicate influence of cognitive biases which can be facilitative or inhibitory) Schematically Encoded Information about self and addiction in LTM Cognitions e.g. Cognitive Expectancies Appraisal: Experience Action Tendencies Stimulus of and Behaviour encoded as Craving drug cue Physiological Reactivity f.ryan@psychology.bbk.ac.uk Adapted from Eysenck,1997
  • 6. Cycle of pre-occupation Attribution of incentive salience Attentional bias Contents of Working memory Attentional bias f.ryan@psychology.bbk.ac.uk
  • 7. A year is a long time in cognitive neuroscience… • fMRI : appetitive cues detected at 33ms Childress et al 2008 • Subliminal priming: 17 ms masked prime can lead to processing bias of smoking cues (Leventhal et al 2008) • Stimuli stored in WM automatically attract attention (Soto et al 2008) f.ryan@psychology.bbk.ac.uk
  • 8. Basic Assumptions • Impairment of executive control due to cognitive processing biases, poor goal maintenance, error detection and compromised decision making. • These cognitive processes can be vulnerability factors for relapse. • These are also potential targets for direct or indirect modification and can index therapeutic gain. (Ryan, (2006) f.ryan@psychology.bbk.ac.uk
  • 9. The “Gateway” and the “Desktop” Working memory <STM+Attentional control> • Maintains representations of external stimuli • Stores action plans • Goal representations • Task relevant information NB:Even when goal maintenance fails in WM, goal is still retrievable from LTM ! Kane, MJ & Engle RW (2003) Working memory capacity and the control of attention: The contribution of goal neglect, response competition, and task set to Stroop interference. J Exptl Psych:(Gen) 132. 47-70 f.ryan@psychology.bbk.ac.uk
  • 10. Three Executive Functions • Shifting (e. g . Switching from addition to subtraction-or from addiction to sobriety ?) • Updating (Monitoring progress, keeping track or goal maintenance- or “I am not going to use today” ?) • Inhibition (suppressing pre-potent responses e.g. Stroop task or anti-saccade task or “I will not dwell on my thoughts about drinking”) Miyake et al (2000) The unity and diversity of executive functions and their contributions to complex “frontal lobe” tasks: A latent variable analysis. Cognitive Psychology 41. 49-100. f.ryan@psychology.bbk.ac.uk
  • 11. Motivational Enhancement • Ambivalence is seen as conflict between controlled and automatic processes rather than a “balance sheet” • Focus on decision making and goal specification is consistent with recruiting working memory processes and exerting a “top-down” regulation. f.ryan@psychology.bbk.ac.uk
  • 12. Therapeutic strategies with potential for increasing cognitive control • Goal specificity • Stimulus Control: know those triggers • Implementation intentions • Be aware of and attempt to correct cognitive biases • Identify alternative rewards/goals • Self-monitoring • Distance /de- centre / mindfulness meditation • Challenge expectancies and implicit cognitions via behavioural experiments • Support self-efficacy f.ryan@psychology.bbk.ac.uk
  • 13. Implementing intentions to change • If situation X occurs at time Y I will perform behaviour Z e.g. “If I have money when I get paid on Friday I will do my shopping before visiting the cocaine dealer” “If I am offered alcohol to drink at the party I will say no thanks, but I would love a mineral water”. Prestwich et al ( in Wiers & Stacy, 2006) f.ryan@psychology.bbk.ac.uk
  • 14. Summary • In the context of addiction, attentional bias prioritises cue detection and infiltration of working memory in a reciprocal way. • This compromises executive control. • If therapeutic intervention can increase cognitive control (e.g. by capturing WM resources) it is likely to reduce preoccupation with salient cues and attendant cue reactivity. f.ryan@psychology.bbk.ac.uk
  • 15. “The Road to recovery…is paved with good rehearsals.” • Enhanced outcome in addiction requires changes in both controlled and automatic processing • Automatic processes, previously overlooked, can be reversed through practice and pre-empted by a range of techniques relying on goal maintenance and cognitive control. • “Tried & tested” interventions need to delineate and accentuate the role of implicit cognitive processes. • Emerging cognitive bias reversal technologies need to be evaluated and developed for further use. • To maximise efficiency these need to be easily available. f.ryan@psychology.bbk.ac.uk
  • 16. Selected References Childress, A R et al (2008) Prelude to passion: Limbic activation by “unseen” drug and sexual cues. ( click to view) Leventhal, A.M.et al (2008). Subliminal processing of smoking related and affective cues in tobacco addiction. Experimental and Clinical Psychopharmacology. 4. 301-312 Ryan, F. (2002) Detected, Selected and Sometimes Neglected: Cognitive processing of cues in addiction. Experimental and Clinical Psychopharmacology. 10. 67-76. Ryan, F. (2006) Appetite Lost and Found : Cognitive Psychology in the Addiction Clinic. In Cognition and Addiction. Munafo, M. & Albery, I. (Eds) OUP Soto, D. et al. (2008) Automatic Guidance of Attention by Working Memory. Trends in Cognitive Sciences 342-348 Wiers, W.W., & Stacy, A.W. (2006) Handbook of implicit cognition and addiction.(Eds) Sage. London. f.ryan@psychology.bbk.ac.uk

Editor's Notes

  1. Inhibition is the most important in present context and three latent variables correlate .42-.63