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HYPERTENSION
A systolic blood pressure greater than 140 mmHg and
the diastolic pressure greater than 90 mmHg based on
the average of two or more accurate blood pressure
measurements taken during two or more compacts with
the health care provider.
Pathophysiology
โ€ข Hypertension can result from;
๏ƒผ An increase in cardiac output
๏ƒผAn increase in peripheral resistance (constriction of blood vessels)
๏ƒผOr both
โ€ข For hypertension to occur, there must be a change in one or more
factors affecting peripheral resistance or cardiac output
โ€ข A problem with the bodyโ€™s control systems that monitor or regulate
pressure
Causes
โ€ข Increased sympathetic nervous system activity related to dysfunction
of autonomic nervous system
โ€ข Increased renal reabsorption of sodium, chloride, and water related
to genetic variation in the pathways by which the kidneys handle
sodium
โ€ข Increased activity of the renin-angiotensin-aldosterone system
resulting in expansion of extracellular fluid volume and systemic
vascular resistance
Contโ€ฆ
โ€ข Decreased vasodilation of the arterioles related to dysfunction of
vascular endothelium
โ€ข Resistance to insulin action which maybe a common factor linking
hypertension, type 2 diabetes mellitus, hypertriglyceridemia, obesity,
and glucose intolerance
Risk factors
โ€ข Family history
โ€ข Life style (sedentarily, obesity, smoking etc)
โ€ข

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  • 1. HYPERTENSION A systolic blood pressure greater than 140 mmHg and the diastolic pressure greater than 90 mmHg based on the average of two or more accurate blood pressure measurements taken during two or more compacts with the health care provider.
  • 2. Pathophysiology โ€ข Hypertension can result from; ๏ƒผ An increase in cardiac output ๏ƒผAn increase in peripheral resistance (constriction of blood vessels) ๏ƒผOr both โ€ข For hypertension to occur, there must be a change in one or more factors affecting peripheral resistance or cardiac output โ€ข A problem with the bodyโ€™s control systems that monitor or regulate pressure
  • 3. Causes โ€ข Increased sympathetic nervous system activity related to dysfunction of autonomic nervous system โ€ข Increased renal reabsorption of sodium, chloride, and water related to genetic variation in the pathways by which the kidneys handle sodium โ€ข Increased activity of the renin-angiotensin-aldosterone system resulting in expansion of extracellular fluid volume and systemic vascular resistance
  • 4. Contโ€ฆ โ€ข Decreased vasodilation of the arterioles related to dysfunction of vascular endothelium โ€ข Resistance to insulin action which maybe a common factor linking hypertension, type 2 diabetes mellitus, hypertriglyceridemia, obesity, and glucose intolerance
  • 5. Risk factors โ€ข Family history โ€ข Life style (sedentarily, obesity, smoking etc) โ€ข