This report focuses on study of behavior of a human knee cartilage on application of point load. A cartilage is a tissue which covers the long bones at the knee joint.it is known as articular cartilage in the medical world. It prevents osteoarthritis and other knee related injuries. The main challenge of this project was to define material properties of bone and cartilage in ANSYS workbench. Initially the physical structure and function of knee bone and cartilage is defined and all the material properties are defined in workbench and in the subsequent section a thorough explicit analysis is done on ANSYS workbench and force vs displacement, internal energy-time graphs are plotted. Next, a structural and 2D analysis done in ANSYS –APDL. Next an explicit analysis done in LS-Dyna and plots for displacement-force and Internal energy-time are determined.