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7.4 Human Genetics and Pedigrees
KEY CONCEPT
A combination of methods is used to study human
genetics.
7.4 Human Genetics and Pedigrees
Human genetics follows the patterns seen in other
organisms.
• The basic principles of genetics are the same in all sexually
reproducing organisms.
– Inheritance of many human
traits is complex.
– Single-gene traits are
important in understanding
human genetics.
7.4 Human Genetics and Pedigrees
Females can carry sex-linked genetic disorders.
• Males (XY) express all of their sex linked genes.
• Expression of the disorder depends on which parent carries
the allele and the sex of the child.
X
Y
7.4 Human Genetics and Pedigrees
A pedigree is a chart for tracing genes in a family.
• Phenotypes are used to infer genotypes on a pedigree.
• Autosomal genes show different patterns on a pedigree
than sex-linked genes.
7.4 Human Genetics and Pedigrees
• If the phenotype is more common in males, the gene is
likely sex-linked.
7.4 Human Genetics and Pedigrees
Several methods help map human chromosomes.
• A karyotype is a picture of all chromosomes in a cell.
X Y
7.4 Human Genetics and Pedigrees
• Karyotypes can show changes in chromosomes.
– deletion of part of a chromosome or loss of a
chromosome
– large changes in chromosomes
– extra chromosomes or duplication of part of a
chromosome

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hssb0704t_powerpresDNA as the transforming principle..ppt

  • 1. 7.4 Human Genetics and Pedigrees KEY CONCEPT A combination of methods is used to study human genetics.
  • 2. 7.4 Human Genetics and Pedigrees Human genetics follows the patterns seen in other organisms. • The basic principles of genetics are the same in all sexually reproducing organisms. – Inheritance of many human traits is complex. – Single-gene traits are important in understanding human genetics.
  • 3. 7.4 Human Genetics and Pedigrees Females can carry sex-linked genetic disorders. • Males (XY) express all of their sex linked genes. • Expression of the disorder depends on which parent carries the allele and the sex of the child. X Y
  • 4. 7.4 Human Genetics and Pedigrees A pedigree is a chart for tracing genes in a family. • Phenotypes are used to infer genotypes on a pedigree. • Autosomal genes show different patterns on a pedigree than sex-linked genes.
  • 5. 7.4 Human Genetics and Pedigrees • If the phenotype is more common in males, the gene is likely sex-linked.
  • 6. 7.4 Human Genetics and Pedigrees Several methods help map human chromosomes. • A karyotype is a picture of all chromosomes in a cell. X Y
  • 7. 7.4 Human Genetics and Pedigrees • Karyotypes can show changes in chromosomes. – deletion of part of a chromosome or loss of a chromosome – large changes in chromosomes – extra chromosomes or duplication of part of a chromosome