This document discusses how to succeed in the 4th Industrial Revolution. It begins with learning objectives about understanding the 4th IR, its impact, and how to apply it to biomedicine. It then discusses trends like globalization, technology, and managing millennials. Key technologies are outlined, like the Internet of Things, artificial intelligence, 5G, augmented reality, 3D printing, drones, biometrics, blockchain and quantum computing. Issues around unemployment, inequality, and ensuring AI safety are addressed. The document provides advice on how to empower societies to master technologies, prioritize futures through design rather than default, focus on key values, question algorithms, adapt skills, and protect data to succeed in the future.