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holla holla
1) Why can the recombination rate never exceed 50%?
a) Each crossing-over event only involves 2 of the 4 chromatids in a tetrad
b)When the recombination rate equals 50% the two genes must be on different chromosomes
c)The occurrence of >1 crossover between two genes prevents the recombination rate from
exceeding 50%
d)Only 50% of recombinant gametes are viable
2)Why are genetic distances an imperfect representation of physical distances on the
chromosome?
i)genetic distances are relative whereas physical distances can be expressed in base pairs
II)Every base pair has the same chance of being the site of a crossing over
III)There are more base pairs than genome features that can be mapped via linkage mapping
IV)The probability of crossing over is different for different chromosomal regions
3)Association mapping works because...............
I)genealogical research is producing pedigrees for large families
II)alleles causing trait variation are in linkage disequilibrium with alleles in the founding linkage
III)All loci in the genome will reach linkage equilibrium after a small number of generations
IV)alleles causing trait variation are in linkage equilibrium with alleles in the founding linkage

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holla holla 1) Why can the recombination rate never exceed 50-- a).pdf

  • 1. holla holla 1) Why can the recombination rate never exceed 50%? a) Each crossing-over event only involves 2 of the 4 chromatids in a tetrad b)When the recombination rate equals 50% the two genes must be on different chromosomes c)The occurrence of >1 crossover between two genes prevents the recombination rate from exceeding 50% d)Only 50% of recombinant gametes are viable 2)Why are genetic distances an imperfect representation of physical distances on the chromosome? i)genetic distances are relative whereas physical distances can be expressed in base pairs II)Every base pair has the same chance of being the site of a crossing over III)There are more base pairs than genome features that can be mapped via linkage mapping IV)The probability of crossing over is different for different chromosomal regions 3)Association mapping works because............... I)genealogical research is producing pedigrees for large families II)alleles causing trait variation are in linkage disequilibrium with alleles in the founding linkage III)All loci in the genome will reach linkage equilibrium after a small number of generations IV)alleles causing trait variation are in linkage equilibrium with alleles in the founding linkage