Hippo signaling is a conserved pathway that controls cell prolifcratio.pdf
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Hippo signaling is a conserved pathway that controls cell prolifcration, apoptosis (cell death), and organ size in response to cell density. At low cell density (Figure I, on the left), transcription co-activators YAP and TAZ enter the nucleus and induce expression of genes that favor cell growth and proliferation. As cell density increases (figure 2 on the right), interactions between membrane-bound FAT4 receptors and DCHS 1/2 on neighboring cells trigger activation of cytoplasmic kinases Mst l /2 and LATS1/2. These kinases phosphorylate TAZ/YAP and prevent them from entering the nucleus, thereby reducing gene expression. 27. What is the ligand in this pathway? 28. What is the receptor in this pathway? 29. What are the target proteins in this pathway? What type of proteins are these (we've seen these in class during Week 3 )? 30. What happens when the target proteins are phosphorylated? 31. What is the ultimate cellular response if this pathway is activated?.
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Given an exponential distribution with = 20 , what is the probability that the arrival time is a. less
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(Click on the following icon in order to copy its contents into a spreadsheet.) Enter the portfolio
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Given $100-000 to invest- construct a value-weighted portfolio of the (1).pdf
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Given an array nums of size n, return the majority element.
The majority element is the element that appears more than round(n/2) times. You may assume
that the majority element always exists in the array.
Use the code template main_find_major_element
main_find_major_element:
#include <iostream>
#include <vector>
#include <algorithm>
using namespace std;
// implement the function here.
int findMajorityElement(vector< int > &v)
{
return 0;
}
int main()
{
int n;
cout << "Enter the size of the vector: ";
cin >> n;
vector< int > input;
int element;
cout << "Enter the elements of the vector: ";
for ( int i = 0; i < n; i++)
{ cin >> element;
input.push_back(element);
}
int result = findMajorityElement(input);
cout << "The Majority Element is: " << result << endl;
return 0;
}
Examples:
Input:
Output:
3
Input:
Output:
2.
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holla holla
1) Why can the recombination rate never exceed 50%?
a) Each crossing-over event only involves 2 of the 4 chromatids in a tetrad
b)When the recombination rate equals 50% the two genes must be on different chromosomes
c)The occurrence of >1 crossover between two genes prevents the recombination rate from
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d)Only 50% of recombinant gametes are viable
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II)Every base pair has the same chance of being the site of a crossing over
III)There are more base pairs than genome features that can be mapped via linkage mapping
IV)The probability of crossing over is different for different chromosomal regions
3)Association mapping works because...............
I)genealogical research is producing pedigrees for large families
II)alleles causing trait variation are in linkage disequilibrium with alleles in the founding linkage
III)All loci in the genome will reach linkage equilibrium after a small number of generations
IV)alleles causing trait variation are in linkage equilibrium with alleles in the founding linkage.
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Megakaryocytes Adipose cells Immature blood cells.
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