Nowadays semantic networks become more important in industry and modern science. For this reason there is a need for an efficient tool allowing preparation and navigation through complex data spaces. We present the novel Topic Map tool H-Maps, which offers a web based navigator providing an enhanced utilization and graphical visualization of semantic networks. Present applications transform existing content to subject-centric Topic Map representations in a one-way fashion. Preserving the advantage of transferring diverse back ends into a unified topic map in existing applications the H-Maps approach goes one step further. The resulting topic map structure can be examined and extended with an iterative procedure. Especially in science this procedure is leading to a considerable improvement of flexibility and performance as can be shown within projects of computational biology.

1. H-Maps: An Efficient Approach for Graphical Visualization and Navigation of Topic Maps and Data Representation in Computational Biology Dr. Steffen Hüttner Hölle & Hüttner AG Derendinger Str. 40 72072 Tübingen Email: lifescience@h-net.com

3. Applications in Computional Biology R&D projects EndoPlas (supported by BMBF) PASSAGE (supported by the Ministery of Sciences Baden-Württemberg)

9. PyroMAP – Mapping Properties Realisation as Type Role1 Role1 Titel Name huh:title Autor Association huh:author Written by Author Zusammenfassung Occurrence huh:abstract Datum Occurrence huh:Date Kurztitel Variant Name huh:shortTitle URL Occurrence huh:url Verlag Association huh:publishinghouse Published by Publishing House ISBN Occurrence huh:isbn ISSN Occurrence huh:issn Erfinder Association huh:inventor Invented from Inventor Patent-Nummer Occurrence huh:patentnr Vortragender Association Huh:lecturer Lectured by Lecturer Erscheinungsort Association huh:place place of publication Place Verweise Umsetzung als Typ Role1 Role1 Notizen Association huh:note Note Note Schlagwörter Association huh:tag Tag Tag Verweise Association Huh:related (*1) Name of Parent Collection (*1) Name of Parent Collection (*1)

10. PyroMAP – Overview Data Streaming Research Internet Browser Internet Browser Browser PlugIn Zotero SQL-Datenbank Topic Map Mapper Topic Map Engine User in Research PyroMAP Ontologie RDF File Topic Map Navigator Topic Map File

16. Find the right way: Map of Knowlegde Combination : Semantic technology and molecular biology Ontology Knowlegde PASSAGE Module Bioinformatics H-Maps Topic Maps Sugar metabolism 10% Expression level Influence sugar metabolism Function Glucose Parameter GAPDH Gene Assay 1 – Stress factor A Experiment Project Hans Müller Person Experiments database Enzyme datanbase Publi- cation Glucose Database Single reads has ressources Cluster

17. Hit the Mark: H-Maps Topic Maps Solution Data PASSAGE Map Experimental results H-Maps Bioinformatic Application Semantic Solution Suite

19. H-Maps Technology The Realisation

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