Public Health - Incidence Prevalence Prevention of HIV in the UK - government situation report 2015 - improving the nations health - Impact on budget nhs england - care quality commission - health tourism - migrant burden - healthcare - hospitals treating disease.
Fast-track the end of AIDS in the EU - practical evidence-based interventions.
Presentation by: ECDC's HIV expert Anastasia Pharris
a two-day meeting under the auspices of the Maltese Presidency of the Council of the European Union (30-31 January 2017), HIV experts from across the European Union discussed how to reverse this trend and how to prepare Europe to achieve the set target of ending AIDS by 2030.
Fast-track the end of AIDS in the EU - practical evidence-based interventions.
Presentation by: Teymur Noori, ECDC
In a two-day meeting under the auspices of the Maltese Presidency of the Council of the European Union (30-31 January 2017), HIV experts from across the European Union discussed how to reverse this trend and how to prepare Europe to achieve the set target of ending AIDS by 2030.
The document discusses HIV infection among children and adolescents in the European Union and European Economic Area (EU/EEA). It provides statistics on new HIV diagnoses from 2006-2015, showing an increase among adolescents ages 15-19. The majority of infections in children under 15 were due to mother-to-child transmission, while most adolescents were infected through heterosexual sex or sex between men. While mother-to-child transmission rates are declining in EU/EEA-born children, transmission remains high in children born outside the EU/EEA to migrant mothers. The document calls for targeted HIV prevention strategies focusing on at-risk groups.
Fast-track the end of AIDS in the EU - practical evidence-based interventions.
Presentation by: Jens Lundgren, CHIP
In a two-day meeting under the auspices of the Maltese Presidency of the Council of the European Union (30-31 January 2017), HIV experts from across the European Union discussed how to reverse this trend and how to prepare Europe to achieve the set target of ending AIDS by 2030.
Although HIV is preventable through effective public health measures, significant HIV transmission continues in Europe. In 2015, almost 30 000 people were diagnosed in European Union and European Economic Area Member States; a rate of 6.3 cases in every 100 000 people (when adjusted for reporting delay).
This report, prepared jointly with the WHO Regional Office for Europe, presents data on HIV and AIDS for the whole European Region, including the EU and EEA countries. Analyses are provided for the EU and EEA region.
This document summarizes the challenges of HIV co-infections in the UK and strategies to address them. It finds that co-infections are a significant problem, especially among men who have sex with men and black communities. Improved surveillance, integrated care, and targeted public health interventions are needed to reduce co-infections in at-risk groups. Developing standardized monitoring indicators can help track progress in diagnosis, treatment, and prevention efforts going forward.
Teymur Noori, ECDC
22nd International AIDS Conference, Amsterdam 2018
2018 European African HIV/AIDS & Hepatitis C Community Summit. "Our Voices Matter for a lasting solution!!"
Fast-track the end of AIDS in the EU - practical evidence-based interventions.
Presentation: ECDC Acting Director Dr Andrea Ammon.
a two-day meeting under the auspices of the Maltese Presidency of the Council of the European Union (30-31 January 2017), HIV experts from across the European Union discussed how to reverse this trend and how to prepare Europe to achieve the set target of ending AIDS by 2030.
Fast-track the end of AIDS in the EU - practical evidence-based interventions.
Presentation by: ECDC's HIV expert Anastasia Pharris
a two-day meeting under the auspices of the Maltese Presidency of the Council of the European Union (30-31 January 2017), HIV experts from across the European Union discussed how to reverse this trend and how to prepare Europe to achieve the set target of ending AIDS by 2030.
Fast-track the end of AIDS in the EU - practical evidence-based interventions.
Presentation by: Teymur Noori, ECDC
In a two-day meeting under the auspices of the Maltese Presidency of the Council of the European Union (30-31 January 2017), HIV experts from across the European Union discussed how to reverse this trend and how to prepare Europe to achieve the set target of ending AIDS by 2030.
The document discusses HIV infection among children and adolescents in the European Union and European Economic Area (EU/EEA). It provides statistics on new HIV diagnoses from 2006-2015, showing an increase among adolescents ages 15-19. The majority of infections in children under 15 were due to mother-to-child transmission, while most adolescents were infected through heterosexual sex or sex between men. While mother-to-child transmission rates are declining in EU/EEA-born children, transmission remains high in children born outside the EU/EEA to migrant mothers. The document calls for targeted HIV prevention strategies focusing on at-risk groups.
Fast-track the end of AIDS in the EU - practical evidence-based interventions.
Presentation by: Jens Lundgren, CHIP
In a two-day meeting under the auspices of the Maltese Presidency of the Council of the European Union (30-31 January 2017), HIV experts from across the European Union discussed how to reverse this trend and how to prepare Europe to achieve the set target of ending AIDS by 2030.
Although HIV is preventable through effective public health measures, significant HIV transmission continues in Europe. In 2015, almost 30 000 people were diagnosed in European Union and European Economic Area Member States; a rate of 6.3 cases in every 100 000 people (when adjusted for reporting delay).
This report, prepared jointly with the WHO Regional Office for Europe, presents data on HIV and AIDS for the whole European Region, including the EU and EEA countries. Analyses are provided for the EU and EEA region.
This document summarizes the challenges of HIV co-infections in the UK and strategies to address them. It finds that co-infections are a significant problem, especially among men who have sex with men and black communities. Improved surveillance, integrated care, and targeted public health interventions are needed to reduce co-infections in at-risk groups. Developing standardized monitoring indicators can help track progress in diagnosis, treatment, and prevention efforts going forward.
Teymur Noori, ECDC
22nd International AIDS Conference, Amsterdam 2018
2018 European African HIV/AIDS & Hepatitis C Community Summit. "Our Voices Matter for a lasting solution!!"
Fast-track the end of AIDS in the EU - practical evidence-based interventions.
Presentation: ECDC Acting Director Dr Andrea Ammon.
a two-day meeting under the auspices of the Maltese Presidency of the Council of the European Union (30-31 January 2017), HIV experts from across the European Union discussed how to reverse this trend and how to prepare Europe to achieve the set target of ending AIDS by 2030.
Presentation by ECDC HIV expert Anastasia Pharris on epidemiological challenges for the HIV response in Europe.
Presented at: 16th European AIDS Conference, 26 October 2017, Milan.
ECDC poster at the 16th European AIDS Conference, 2017, Milan.
Authors: Lara Tavoschi, Joana Gomes-Dias, Anastasia Pharris, the EU/EEA HIV Surveillance Network
Although HIV is preventable through effective public health measures, significant HIV transmission continues in Europe. In 2014, almost 30 000 people were diagnosed in European Union and European Economic Area Member States. This slide set includes maps, graphs and tables from the 2014 HIV/AIDS surveillance report, published jointly by ECDC and WHO Europe.
An overview on how European countries have been responding to the HIV epidemic since 2004 based on the commitments as outlined in the Dublin Declaration on Partnership to Fight HIV/AIDS in Europe and Central Asia.
ECDC presentation at the 15th Conference of the International Society of Travel Medicine, 15 May 2017.
Presenter: Teymur Noori
Questions?
Contact info@ecdc.europa.eu
Fast-track the end of AIDS in the EU - practical evidence-based interventions.
Presentation by: Mika Salminen, European HA-REACT project
In a two-day meeting under the auspices of the Maltese Presidency of the Council of the European Union (30-31 January 2017), HIV experts from across the European Union discussed how to reverse this trend and how to prepare Europe to achieve the set target of ending AIDS by 2030.
The document summarizes the status of pre-exposure prophylaxis (PrEP) implementation in Europe based on data from 2018-2019. It finds that while formal PrEP rollout has been slow, especially in Eastern Europe and Central Asia, there is evidence of significant informal PrEP use across countries. As a result, an estimated 500,000 men who have sex with men (MSM) want or need PrEP but are unable to access it, representing a "PrEP gap" in Europe. Barriers to wider PrEP implementation include cost and lack of public funding in some countries.
Presentation during the EU session "Eliminationm of hepatitis B and C in teh EU: challenges and opportunities", at the International Liver Congress (ILC) 2017 in Amsterdam.
Presenter: Erika Duffell, European Centre for Disease Prevention and Control (ECDC)
In 2014, over 57 000 new cases of hepatitis B and C were reported. 22 442 cases of hepatitis B virus infection were reported in 30 EU/EEA Member States and 35 321 cases of hepatitis C were reported from 28 EU/EEA Member States.
Data and trends on hepatitis B and C for the countries of the European Union and European Economic Area.
2015 data.
See also ECDC's Annual Epidemiological Report: https://ecdc.europa.eu/en/annual-epidemiological-reports
This document provides a regional overview of HIV/AIDS trends in Asia and the Pacific from 1990-2013. It summarizes that there are currently 4.8 million people living with HIV in the region, with new infections declining significantly since 2001 but remaining largely unchanged in the past 5 years. Treatment coverage has increased substantially, with 1.56 million people now on ART, however this is still only about one-third of those in need. The challenges ahead include addressing gaps in prevention for key populations and along the treatment cascade.
HIV/AIDS data Hub Asia Pacific -Malaysia 2014Dr. Rubz
This document provides a summary of HIV/AIDS data for Malaysia across multiple indicators:
- HIV prevalence is highest among key populations like people who inject drugs, female sex workers, and men who have sex with men. Condom use and safe injection practices have increased over time but remain below optimal levels.
- The number of reported HIV infections and AIDS-related deaths has declined in recent years. Most HIV transmissions are through heterosexual contact and injecting drug use.
- Vulnerability remains high as many key populations lack comprehensive HIV knowledge and access to prevention programs, testing, and treatment.
- Government spending on HIV has increased but more funding needs to be directed towards programs for key populations at higher
Presentation from the opening session of the 17th European AIDS Conference (EACS) 2019, Basel, Switzerland.
Presenter: Anastasia Pharris, European Centre for Disease Prevention and Control.
Data and trends from the ECDC Annual Epidemiological reports for 2016 on:
Chlamydia (http://bit.ly/AERch16)
Lymphogranuloma venereum (http://bit.ly/AERLGV16)
Gonorrhoea (http://bit.ly/AERsy16)
Syphilis (http://bit.ly/AERsy16)
Congenital syphilis (http://bit.ly/AERcs16)
See also: https://ecdc.europa.eu/en/annual-epidemiological-reports
This document analyzes EU surveillance data from 2009-2014 on shigellosis, a bacterial infection transmitted through contaminated food or water or directly from person to person through feces. The analysis found that domestically-acquired shigellosis cases increased over this period and accounted for over half of reported cases in 2014, with the proportion of cases among men doubling. Male-to-female ratios were highest among domestic cases, suggesting ongoing sexual transmission of certain Shigella strains like S. flexneri serotype 3a among men who have sex with men in Europe. The authors conclude countries should investigate domestic male cases and sexual transmission more and report such data to help monitor trends and facilitate public health interventions.
Kathleen Brady from the Philadelphia Department of Public Health presented her annual updated on the HIV Epidemic in Philadelphia at a February 2015 combined meeting of the Philadelphia Ryan White Part A Planning Council and the HIV Prevention Planning Group.
Dr. Kathleen Brady (AACO)'s annual epidemiological update. This presentation was given to the Philadelphia EMA Ryan White Planning Council on Thursday, February 20, 2014.
Kathleen Brady - HIV in Philadelphia (Annual Epidemiological Presentation)Office of HIV Planning
On April 27, 2016, Kathleen Brady of the Philadelphia AIDS Activities Coordinating Office (AACO) presented her annual review of the HIV Epidemic in Philadelphia and the surrounding areas.
Surveillance data from 2013 show high numbers of newly diagnosed hepatitis B and C cases notified across Europe. Chronic cases dominate across both diseases with a marked variation between countries: in 2013, 19 930 cases of hepatitis B virus infection were reported in 28 EU/EEA Member States, a crude rate of 4.4 per 100 000 population. 26 EU/ EEA Member States recorded 32 512 cases of hepatitis C resulting in a crude rate of 9.9 per 100 000 population.
This document provides information about HIV/AIDS, including:
- It defines endemic, epidemic, and pandemic, with AIDS classified as a pandemic.
- As of 2003, it was estimated that 40 million people worldwide were living with HIV/AIDS, with 25-28.2 million in Sub-Saharan Africa.
- HIV attacks and destroys CD4 cells, weakening the immune system and leaving the body vulnerable to opportunistic infections over time without treatment.
- HIV is transmitted through direct contact with infected bodily fluids like blood, semen, vaginal fluids. It cannot be transmitted by casual contact.
- Prevention strategies include blood screening, education on safer sex practices, STI treatment, and preventing mother
This document provides information about HIV/AIDS, including how it is transmitted and prevented. It defines HIV as the virus that compromises the immune system, and AIDS as the final stage when the immune system is severely damaged. Some key statistics are presented, such as over 1.7 million people in the US being infected since 1981, with 1 in 5 unaware. Common symptoms during HIV emergence from latency are also listed. The document stresses that while there is no cure for HIV, antiretroviral drugs can suppress it and transmission is preventable through condom use and clean needles.
Presentation by ECDC HIV expert Anastasia Pharris on epidemiological challenges for the HIV response in Europe.
Presented at: 16th European AIDS Conference, 26 October 2017, Milan.
ECDC poster at the 16th European AIDS Conference, 2017, Milan.
Authors: Lara Tavoschi, Joana Gomes-Dias, Anastasia Pharris, the EU/EEA HIV Surveillance Network
Although HIV is preventable through effective public health measures, significant HIV transmission continues in Europe. In 2014, almost 30 000 people were diagnosed in European Union and European Economic Area Member States. This slide set includes maps, graphs and tables from the 2014 HIV/AIDS surveillance report, published jointly by ECDC and WHO Europe.
An overview on how European countries have been responding to the HIV epidemic since 2004 based on the commitments as outlined in the Dublin Declaration on Partnership to Fight HIV/AIDS in Europe and Central Asia.
ECDC presentation at the 15th Conference of the International Society of Travel Medicine, 15 May 2017.
Presenter: Teymur Noori
Questions?
Contact info@ecdc.europa.eu
Fast-track the end of AIDS in the EU - practical evidence-based interventions.
Presentation by: Mika Salminen, European HA-REACT project
In a two-day meeting under the auspices of the Maltese Presidency of the Council of the European Union (30-31 January 2017), HIV experts from across the European Union discussed how to reverse this trend and how to prepare Europe to achieve the set target of ending AIDS by 2030.
The document summarizes the status of pre-exposure prophylaxis (PrEP) implementation in Europe based on data from 2018-2019. It finds that while formal PrEP rollout has been slow, especially in Eastern Europe and Central Asia, there is evidence of significant informal PrEP use across countries. As a result, an estimated 500,000 men who have sex with men (MSM) want or need PrEP but are unable to access it, representing a "PrEP gap" in Europe. Barriers to wider PrEP implementation include cost and lack of public funding in some countries.
Presentation during the EU session "Eliminationm of hepatitis B and C in teh EU: challenges and opportunities", at the International Liver Congress (ILC) 2017 in Amsterdam.
Presenter: Erika Duffell, European Centre for Disease Prevention and Control (ECDC)
In 2014, over 57 000 new cases of hepatitis B and C were reported. 22 442 cases of hepatitis B virus infection were reported in 30 EU/EEA Member States and 35 321 cases of hepatitis C were reported from 28 EU/EEA Member States.
Data and trends on hepatitis B and C for the countries of the European Union and European Economic Area.
2015 data.
See also ECDC's Annual Epidemiological Report: https://ecdc.europa.eu/en/annual-epidemiological-reports
This document provides a regional overview of HIV/AIDS trends in Asia and the Pacific from 1990-2013. It summarizes that there are currently 4.8 million people living with HIV in the region, with new infections declining significantly since 2001 but remaining largely unchanged in the past 5 years. Treatment coverage has increased substantially, with 1.56 million people now on ART, however this is still only about one-third of those in need. The challenges ahead include addressing gaps in prevention for key populations and along the treatment cascade.
HIV/AIDS data Hub Asia Pacific -Malaysia 2014Dr. Rubz
This document provides a summary of HIV/AIDS data for Malaysia across multiple indicators:
- HIV prevalence is highest among key populations like people who inject drugs, female sex workers, and men who have sex with men. Condom use and safe injection practices have increased over time but remain below optimal levels.
- The number of reported HIV infections and AIDS-related deaths has declined in recent years. Most HIV transmissions are through heterosexual contact and injecting drug use.
- Vulnerability remains high as many key populations lack comprehensive HIV knowledge and access to prevention programs, testing, and treatment.
- Government spending on HIV has increased but more funding needs to be directed towards programs for key populations at higher
Presentation from the opening session of the 17th European AIDS Conference (EACS) 2019, Basel, Switzerland.
Presenter: Anastasia Pharris, European Centre for Disease Prevention and Control.
Data and trends from the ECDC Annual Epidemiological reports for 2016 on:
Chlamydia (http://bit.ly/AERch16)
Lymphogranuloma venereum (http://bit.ly/AERLGV16)
Gonorrhoea (http://bit.ly/AERsy16)
Syphilis (http://bit.ly/AERsy16)
Congenital syphilis (http://bit.ly/AERcs16)
See also: https://ecdc.europa.eu/en/annual-epidemiological-reports
This document analyzes EU surveillance data from 2009-2014 on shigellosis, a bacterial infection transmitted through contaminated food or water or directly from person to person through feces. The analysis found that domestically-acquired shigellosis cases increased over this period and accounted for over half of reported cases in 2014, with the proportion of cases among men doubling. Male-to-female ratios were highest among domestic cases, suggesting ongoing sexual transmission of certain Shigella strains like S. flexneri serotype 3a among men who have sex with men in Europe. The authors conclude countries should investigate domestic male cases and sexual transmission more and report such data to help monitor trends and facilitate public health interventions.
Kathleen Brady from the Philadelphia Department of Public Health presented her annual updated on the HIV Epidemic in Philadelphia at a February 2015 combined meeting of the Philadelphia Ryan White Part A Planning Council and the HIV Prevention Planning Group.
Dr. Kathleen Brady (AACO)'s annual epidemiological update. This presentation was given to the Philadelphia EMA Ryan White Planning Council on Thursday, February 20, 2014.
Kathleen Brady - HIV in Philadelphia (Annual Epidemiological Presentation)Office of HIV Planning
On April 27, 2016, Kathleen Brady of the Philadelphia AIDS Activities Coordinating Office (AACO) presented her annual review of the HIV Epidemic in Philadelphia and the surrounding areas.
Surveillance data from 2013 show high numbers of newly diagnosed hepatitis B and C cases notified across Europe. Chronic cases dominate across both diseases with a marked variation between countries: in 2013, 19 930 cases of hepatitis B virus infection were reported in 28 EU/EEA Member States, a crude rate of 4.4 per 100 000 population. 26 EU/ EEA Member States recorded 32 512 cases of hepatitis C resulting in a crude rate of 9.9 per 100 000 population.
This document provides information about HIV/AIDS, including:
- It defines endemic, epidemic, and pandemic, with AIDS classified as a pandemic.
- As of 2003, it was estimated that 40 million people worldwide were living with HIV/AIDS, with 25-28.2 million in Sub-Saharan Africa.
- HIV attacks and destroys CD4 cells, weakening the immune system and leaving the body vulnerable to opportunistic infections over time without treatment.
- HIV is transmitted through direct contact with infected bodily fluids like blood, semen, vaginal fluids. It cannot be transmitted by casual contact.
- Prevention strategies include blood screening, education on safer sex practices, STI treatment, and preventing mother
This document provides information about HIV/AIDS, including how it is transmitted and prevented. It defines HIV as the virus that compromises the immune system, and AIDS as the final stage when the immune system is severely damaged. Some key statistics are presented, such as over 1.7 million people in the US being infected since 1981, with 1 in 5 unaware. Common symptoms during HIV emergence from latency are also listed. The document stresses that while there is no cure for HIV, antiretroviral drugs can suppress it and transmission is preventable through condom use and clean needles.
This document discusses HIV/AIDS, including its symptoms such as fever, weight loss, and fatigue. It also covers the causes of HIV/AIDS such as infection by the human immunodeficiency virus, and how HIV is transmitted between people through activities like unprotected sex and sharing needles. Finally, the document talks about preventing the transmission of HIV through safe sex practices and needle exchange programs.
P8\; is caused by HIV infection, which weakens the immune system over time. A person can be infected with HIV for many years before developing AIDS. While there is no cure for HIV/AIDS, antiretroviral treatment can suppress the virus and prevent opportunistic infections that are characteristic of AIDS. The document provides details on how HIV is transmitted, the stages of HIV infection and AIDS, common signs and symptoms, and treatments available to manage the disease.
Andrew Hill - treatment of HIV and HCV: branded versus generic medicines Natalia Khilko
This document discusses treatment costs for HIV and hepatitis in Russia compared to global access prices. It finds that drug prices in Russia are much higher, preventing scale-up of treatment. To achieve UNAIDS 90-90-90 targets for HIV treatment in Russia and mass treatment for hepatitis, prices would need to be reduced, possibly through compulsory licensing of patents or local generic production, as done in Thailand and Brazil. The document advocates for standard global prices of $90 per year for HIV treatment and hepatitis B and $90 for a 12-week hepatitis C treatment course.
The document discusses the causes and effects of HIV. The main causes of HIV transmission are through unprotected sexual contact, sharing needles or syringes, and from mother to fetus during pregnancy or breastfeeding. Some effects of HIV include skin conditions like chicken pox or shingles that can affect organs and be life-threatening, as well as AIDS-related dementia which decreases cognitive ability and processing due to neurological impacts even though HIV does not directly infect nerve cells.
HIV AIDS Lecture Presented by me in my Community Dentistry Class, BIBI ASIFA DENTAL COLLEGE, SHAHEED MOHTARMA BENAZIR BHUTTO MEDICAL UNIVERSITY LARKANA, SINDH, PAKISTAN.
The document discusses the history and transmission of HIV/AIDS, noting that the first case was reported in the US in 1981 and over 1 million people had been infected by 2001, with over 400,000 deaths. It emphasizes that HIV can infect anyone and explains that the virus is most often transmitted through unprotected sex and contact with infected bodily fluids. The text provides information on testing, treatment, and prevention methods like condom use and advises readers not to believe HIV is not serious, as there is currently no cure.
The document provides information on HIV/AIDS, including:
1. HIV was first identified in 1981 and there have been two major strains identified, HIV-1 and HIV-2.
2. HIV is transmitted through bodily fluids and can be transmitted sexually or through contact with infected blood.
3. There are three phases of HIV infection eventually resulting in AIDS if not treated. Antiretroviral treatment can suppress the virus and prevent AIDS.
HIV AIDS is one of the most dreadful of all diseases. Newer drugs and drug combination are coming quite frequently. Attempts to design an HIV vaccine is also underway.
This seminar is my attempt this interesting topic with all the latest data I could collect on the internet.
This presentation provides an overview of HIV and AIDS. It defines HIV as a virus that attacks the immune system and destroys the body's ability to fight infections and diseases. It is transmitted through certain body fluids like blood, semen, vaginal fluids, and breast milk. The presentation details how HIV infects and replicates within immune cells called CD4 cells. It explains the stages of HIV infection from the initial window period to the development of AIDS when the immune system is severely compromised. Treatment options are discussed as well as strategies for prevention.
HIV/AIDS originated from chimpanzees in Africa and likely entered the US in the 1970s. In the 1980s, clusters of illnesses in gay men led to the identification of HIV and the disease being named AIDS. The Ryan White CARE Act provided funding for people with HIV/AIDS. Currently over 1 million people live with HIV/AIDS in the US, with higher rates among African Americans and men who have sex with men. Prevention focuses on abstinence, monogamy, and condom use.
How to Make Awesome SlideShares: Tips & TricksSlideShare
Turbocharge your online presence with SlideShare. We provide the best tips and tricks for succeeding on SlideShare. Get ideas for what to upload, tips for designing your deck and more.
SlideShare is a global platform for sharing presentations, infographics, videos and documents. It has over 18 million pieces of professional content uploaded by experts like Eric Schmidt and Guy Kawasaki. The document provides tips for setting up an account on SlideShare, uploading content, optimizing it for searchability, and sharing it on social media to build an audience and reputation as a subject matter expert.
Fast-track the end of AIDS in the EU - practical evidence-based interventions.
Presentation by: Valerie Delpech, Public Health Engand
In a two-day meeting under the auspices of the Maltese Presidency of the Council of the European Union (30-31 January 2017), HIV experts from across the European Union discussed how to reverse this trend and how to prepare Europe to achieve the set target of ending AIDS by 2030.
National and international perspectives of health.pptxlucascyrus
The HIV epidemic affects the health of individuals as well as the households. With effective awareness campaigns and UNAIDS cautions an equal progress in reduction of HIV infections have been observed.
The document provides an overview of HIV/AIDS, including its causes, symptoms, transmission, treatment, and global and national impact. It describes how HIV attacks and destroys CD4 cells, weakening the immune system and leaving the body vulnerable to opportunistic infections. While treatment can suppress the virus and prevent disease progression, there is currently no cure for HIV/AIDS. The document also outlines Nepal's national strategies to prevent new infections, improve quality of life for those living with HIV/AIDS, and reduce stigma through testing and counseling programs, condom promotion, harm reduction services, and antiretroviral treatment.
This document summarizes the global burden of tuberculosis (TB) in 2011. Some key points:
- An estimated 1.4 million people died from TB that year, with over 80% of TB/HIV co-infections occurring in Africa.
- TB incidence rates were highest in Africa, linked to high HIV infection rates. People living with HIV are 20-40 times more likely to develop active TB.
- About 630,000 cases of multi-drug resistant TB were estimated, with over 60% occurring in 5 countries: India, China, Russia, Philippines, and Pakistan.
- 500,000 women and 65,000 children died from TB in 2011, and 10 million children were left orphaned
current hiv situation in india and national aids control programme an overviewikramdr01
The document provides information about an orientation programme for doctors on the National AIDS Control Programme (NACO) in India. It will take place on December 26-27, 2013 at the Government Thiruvarur Medical College and Hospital in Thiruvarur, India. The programme will provide an overview of the current HIV situation in India, NACO's objectives and approaches, national guidelines for detecting HIV, and NACO's comprehensive HIV care and antiretroviral therapy (ART) services.
Сравнение режимов лечения ВИЧ в разрезе различных клинических сценариев.ART...hivlifeinfo
This downloadable slideset summarizes optimal evidence-based antiretroviral therapy management strategies for a series of challenging clinical cases and is based on a satellite symposium presented at HIV Glasgow 2016.
Format: Microsoft PowerPoint (.ppt)
File size: 1.32 MB
Date posted: 11/11/2016
This presentation discusses:
Why it is a Global Health Issue?
Difference between HIV and AIDS?
Signs and Symptoms
Routes of Transmission
Risk factors
Diagnosis
Prevention
Treatment
Dr. Anna Garner presented on updates in HIV and STIs. Key points included:
1) Late HIV diagnosis remains an issue in the UK, with many patients presenting only after developing AIDS-related illnesses. Missed opportunities for earlier testing contribute to late diagnoses.
2) STIs such as LGV have seen resurgences in certain populations. Ocular syphilis can also present an atypical symptom of syphilis infection.
3) Increased HIV and STI testing is needed in high prevalence areas. All healthcare providers should consider HIV in their differential and offer testing when appropriate to diagnose more patients earlier.
This document discusses the lack of recognition of trans and gender diverse (TGD) people in discussions around HIV/AIDS in Australia. While TGD people have a high risk of contracting HIV, accounting for up to 4% of notifications in Australia, they are largely invisible in mainstream discourse and data collection on HIV. The document argues that more research is needed on the lived experiences of TGD people living with HIV in Australia to understand the social challenges they face and improve recognition, care, and support for this at-risk population.
Global Medical Cures™ | HIV TESTING IN USA
DISCLAIMER-
Global Medical Cures™ does not offer any medical advice, diagnosis, treatment or recommendations. Only your healthcare provider/physician can offer you information and recommendations for you to decide about your healthcare choices.
This document discusses World AIDS Day 2017. It provides key facts about HIV/AIDS, including that over 36 million people worldwide are living with HIV, and outlines what life is like for those living with HIV today with effective treatment. The document encourages readers to help end HIV stigma by challenging misconceptions, and suggests ways to get involved on World AIDS Day like wearing a red ribbon to show support.
The document provides information about HIV/AIDS in Pakistan, including:
1) It discusses the objectives and infrastructure of the Enhanced Sindh AIDS Control Program, including voluntary counseling and testing centers, STI clinics, and PPTCT centers.
2) It provides a brief history of HIV, noting it originated from chimpanzees and was first identified in the US in 1981. HIV attacks and destroys CD4 cells, eventually causing AIDS.
3) It discusses HIV transmission, noting the major routes are sexual contact, exposure to infected blood or blood products, and from mother to child during pregnancy, birth, or breastfeeding.
India has seen a 57% reduction in its HIV count between 2001-2011, while Bangladesh and Sri Lanka saw increases of 25%. As of 2011, an estimated 2.1 million people in India were living with HIV. India's epidemic is heterogeneous and concentrated in certain states and sub-populations. Successful prevention efforts have led international figures to praise India's HIV/AIDS prevention model. However, more work remains as even a small increase in prevalence could mean over half a million new infections. The continuum of HIV care involves testing and counseling, treatment of opportunistic infections, anti-retroviral therapy initiation and monitoring, management of co-infections, and adherence support. WHO guidelines recommend treatment for all HIV-positive individuals
This document provides background information on HIV/AIDS and disease surveillance services. It discusses how HIV first emerged in the 1980s and has since spread globally. Disease surveillance involves the ongoing systematic collection and analysis of data to monitor disease spread and inform prevention and control efforts. The document then reviews studies on HIV prevalence in various countries and age groups. It also discusses theories relevant to disease surveillance and HIV control, including how education and awareness building can impact prevention efforts.
This document summarizes the position statement of the American College of Preventive Medicine (ACPM) regarding routine HIV screening. The ACPM supports routine HIV screening for all adolescents and adults ages 13-64, as well as pregnant women, based on evidence that risk-based screening is inadequate and leads to low testing rates, lack of HIV status awareness, and late diagnoses. The ACPM endorses opt-out consent procedures, use of rapid HIV tests, streamlined counseling separate from screening, and linking patients to treatment. The organization also recommends annual repeat testing for high-risk groups and repeat testing every 5 years for the general population.
This document introduces provider-initiated HIV testing and counseling (PITC). It discusses the evolution of HIV testing policies from mandatory testing to voluntary counseling and testing (VCT) to the current recommendation of PITC. PITC involves recommending HIV testing to all patients attending health facilities in generalized epidemics, and selectively in concentrated/low-level epidemics, using an opt-out approach. It provides guidance on implementing PITC, including pre-test information and consent, testing procedures, and post-test counseling for both HIV-positive and negative patients.
These lecture slides, by Dr Sidra Arshad, offer a simplified look into the mechanisms involved in the regulation of respiration:
Learning objectives:
1. Describe the organisation of respiratory center
2. Describe the nervous control of inspiration and respiratory rhythm
3. Describe the functions of the dorsal and respiratory groups of neurons
4. Describe the influences of the Pneumotaxic and Apneustic centers
5. Explain the role of Hering-Breur inflation reflex in regulation of inspiration
6. Explain the role of central chemoreceptors in regulation of respiration
7. Explain the role of peripheral chemoreceptors in regulation of respiration
8. Explain the regulation of respiration during exercise
9. Integrate the respiratory regulatory mechanisms
10. Describe the Cheyne-Stokes breathing
Study Resources:
1. Chapter 42, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 36, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 13, Human Physiology by Lauralee Sherwood, 9th edition
- Video recording of this lecture in English language: https://youtu.be/kqbnxVAZs-0
- Video recording of this lecture in Arabic language: https://youtu.be/SINlygW1Mpc
- Link to download the book free: https://nephrotube.blogspot.com/p/nephrotube-nephrology-books.html
- Link to NephroTube website: www.NephroTube.com
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Overall life span (LS) was 1671.7±1721.6 days and cumulative 5YS reached 62.4%, 10 years – 50.4%, 20 years – 44.6%. 94 LCP lived more than 5 years without cancer (LS=2958.6±1723.6 days), 22 – more than 10 years (LS=5571±1841.8 days). 67 LCP died because of LC (LS=471.9±344 days). AT significantly improved 5YS (68% vs. 53.7%) (P=0.028 by log-rank test). Cox modeling displayed that 5YS of LCP significantly depended on: N0-N12, T3-4, blood cell circuit, cell ratio factors (ratio between cancer cells-CC and blood cells subpopulations), LC cell dynamics, recalcification time, heparin tolerance, prothrombin index, protein, AT, procedure type (P=0.000-0.031). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and N0-12 (rank=1), thrombocytes/CC (rank=2), segmented neutrophils/CC (3), eosinophils/CC (4), erythrocytes/CC (5), healthy cells/CC (6), lymphocytes/CC (7), stick neutrophils/CC (8), leucocytes/CC (9), monocytes/CC (10). Correct prediction of 5YS was 100% by neural networks computing (error=0.000; area under ROC curve=1.0).
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3. HIV in the UK – Situation Report 2015: Incidence, prevalence and prevention
3
Contents
About Public Health England 2
Key findings and prevention implications 4
Number of people living with HIV 7
HIV Testing 16
HIV Prevention 21
References 23
Appendices 25
4. HIV in the UK – Situation Report 2015: Incidence, prevalence and prevention
4
Key findings and prevention implications
Overall, the number of people living with HIV in the UK continues to increase and
the number living with undiagnosed HIV remains high
In 2014, an estimated 103,700 people (95% credible interval (CrI) 97,500-112,700)
were living with HIV (PLWH) in the UK, of whom 69,200 (CrI 65,000-75,100) were men
and 34,400 (CrI 31,700-39,100) were women. This compares to an estimated 100,000
PLWH in 20131
. The overall HIV prevalence in the UK in 2014 was 1.9 per 1,000
people aged 15 and over. In 2014, an estimated 18,100 (17%) PLWH were unaware of
their infection and at risk of unknowingly passing on HIV if having sex without a
condom, and this is similar to revised estimates from 2013 (18,219 (18%)). The
estimated number and proportion of people living with undiagnosed HIV have declined
since 2010 (from 22,800 and 25% respectively), with the majority of this decline
happening before 2012.
Despite a decline in undiagnosed HIV infections among men who have sex with
men there is evidence that rates of ongoing HIV transmission remain high
An estimated 45,000 (CrI 41,900-49,500) men living with HIV in the UK in 2014 had
acquired their infection through sex with other men (MSM), up from 43,000 in 2013.
Among MSM aged 15-44, one in 20 is estimated to be living with HIV (48.7 MSM (CrI
41.2-58.1) per 1,000). An estimated 6,500 (CrI 3,500-10,900), 14%) MSM were
unaware of their infection in 2014, a decline from 8,500 (CrI 4,600-13,900, 22%) in
2010. HIV testing coverage among MSM attending sexual health (STI) clinics has
increased over this period and is likely to be the reason for the estimated decline in
undiagnosed infections and observed increases in new diagnoses. Despite this there
remains a high HIV incidence in MSM, with an indication of a small sequential increase
in 2013 and 2014 (Figure 4).
HIV testing in STI clinic attendees continues to increase throughout most of
England with high coverage particularly among MSM
In England, 1.43 million people attended a STI clinic in 2014, with 69% of eligible
attendees having an HIV test. Testing coverage was highest among MSM (87%,
90,719/104,028) and 179/223 (80%) of STI clinics across England achieved the British
Association for Sexual Health and HIV (BASHH) standard [4]. Coverage was less
1 Differences between estimates for PLWH in 2014 in this report and last year’s report are due to changes in the
mathematical model and data sources used to calculate the estimates
5. HIV in the UK – Situation Report 2015: Incidence, prevalence and prevention
5
comprehensive for eligible heterosexual men (77%, 382,743/497,455) and women2
(62%, 504,249/814,459), and only 33/223 (15%) STI clinics achieved 80% HIV test
coverage.
Prompt diagnosis remains a priority for heterosexuals living with HIV
Among the 54,100 (CrI 49,000-62,400) people (men (21,300), women (32,700)) living
in the UK who had acquired HIV through heterosexual sex, more than one in five (21%
(11,200 (CrI 6,200-18,900) were unaware of their HIV infection, with a higher proportion
of those living outside London unaware (24% out of London undiagnosed compared to
12% in London). Among heterosexuals aged 15-44 in the UK, almost one in every
1,000 is estimated to be living with HIV (0.9 per 1,000 (CrI 0.7-1.1), with higher
prevalence’s among black African heterosexual men (one in 56) and women (one in
22). Late diagnosis remains a significant problem among heterosexuals with 55%
(1,381/2,490) newly diagnosed at a late stage of infection in 2014, of whom 51%
(700/1,381) were black African. There is a need for expanded and scaled up HIV
testing across the UK to reduce undiagnosed infection and late diagnosis in line with
national HIV testing guidance [5-7].
The ongoing high rates of HIV transmission and acquisition among men who
have sex with men emphasise the need for high impact, appropriately tailored
combination prevention strategies and programmes
Despite high and increasing rates of HIV testing by MSM coupled with high levels of
effective ART treatment coverage for those diagnosed positive, there remains evidence
of ongoing HIV transmission among MSM. Ensuring optimal implementation of effective
prevention interventions such as condom use is required to reduce infections, in
addition to addressing the wider determinants of poor sexual health among MSM which
are closely linked to HIV infection [21].
The evidence for efficacy and effectiveness of antiretroviral agents to reduce onward
transmission from people who are HIV positive [14,16] as well as prevent HIV
acquisition in those who are HIV free (HIV – Pre Exposure Prophylaxis HIV – PrEP)
[12,13] continues to expand, making important additions to the prevention toolkit.
In England all anti-retroviral drugs, whether for treatment or prevention, are
commissioned by NHS England. In June 2015 the use of ART by people who are HIV
positive to both prevent as well as treat HIV infection (treatment as prevention or TasP)
was approved by NHS England [20]. At present there is no publicly funded PrEP
2
Figures for women include sexual reproductive health clinic HIV testing data which may reflect a lower HIV risk
population
6. HIV in the UK – Situation Report 2015: Incidence, prevalence and prevention
6
programme in any of the four UK nations. NHS England is currently working to make
commissioning decisions about PrEP, with a outcome expected in the summer of 2016.
HIV risk reduction messages
Early diagnosis of HIV infection enables better treatment outcomes and reduces the
risk transmitting the infection to others. Have an HIV test if you think you may have
been at risk.
Always use a condom correctly and consistently, and until all partners have had a
sexual health screen.
Reduce the number of sexual partners and avoid overlapping sexual relationships.
Men who have sex with men are advised to have an HIV and STI screen at least
annually, and every three months if having unprotected sex with new or casual
partners.
Unprotected sex with partners believed to be of the same HIV status (serosorting) is
unsafe. For the HIV positive person, there is a high risk of acquiring other STIs and
hepatitis. For the HIV negative person, there is a high risk of acquiring HIV infection
(6,500 of MSM remain unaware of their HIV infection) as well as of acquiring STIs and
hepatitis.
Black African men and women are advised to have an HIV test and a regular HIV
and STI screen if having unprotected sex with new or casual partners.
How to get an HIV test: Go to an open-access sexually transmitted infection (STI)
clinic (some clinics in large cities are offering ‘fast-track’ HIV testing) or go to a
community testing site (http://www.aidsmap.com/hiv-test-finder).
Ask your GP for an HIV test – nowadays there is no need for a lengthy discussion
about the test, it just involves having blood taken, or even a finger prick.
Ask online for a self-sampling kit (www.freetesting.hiv).
7. HIV in the UK – Situation Report 2015: Incidence, prevalence and prevention
7
Number of people living with HIV
Two methods are used to estimate the number of people living with HIV including those
undiagnosed. The first, the multi-parameter evidence synthesis model (MPES),
produces annual estimates for all most at risk populations, while the second is a CD4
back-calculation model that provides undiagnosed prevalence as well as incidence
estimates restricted to MSM populations. These figures complement the data on
diagnosed HIV prevalence presented in the HIV new diagnoses, treatment and care
2015 report [1].
In 2015, there have been significant revisions to the MPES used to estimate the number
and proportion of people living with undiagnosed HIV (full methodology published in [2]).
This is due to changes to the sources of primary data used by the model over the past
few years, including changes to the unlinked anonymous serosurveys and behavioural
surveys (eg NATSAL [3]) and a greater reliance on data from STI clinics. In this report,
the revised MPES methodology was used to generate annual estimates and trend data
for the years 2010 to 2014. Revisions to the methodology in 2015 mean that figures in
this report may be different to previously published estimates.
In 2014, there were an estimated 103,700 people living with HIV (PLWH) in the UK
(95% credible interval (CrI) 97,500-112,700). An estimated 18,100 (17%) (CrI 12,100-
26,900) people were unaware of their infection, with differences between exposure
groups (Figure 1 and Appendix 1). Since 2010 the number of PLWH has increased
(from 91,900) while the number and proportion undiagnosed (22,800, 25%) declined
before stabilising in recent years (Appendix 2).
The HIV prevalence among those aged 15-44 years in 2014 in the UK was estimated to
be 2.3 per 1,000 population (CrI 2.1-2.5), 2.8 per 1,000 men and 1.7 per 1,000 women.
The HIV epidemic remains largely concentrated among gay, bisexual men and other
MSM and men and women of black African ethnicity.
8. HIV in the UK – Situation Report 2015: Incidence, prevalence and prevention
8
Figure 1. Estimated number1
of people living with HIV (both diagnosed and
undiagnosed) all ages: UK, 2014
9. HIV in the UK – Situation Report 2015: Incidence, prevalence and prevention
9
Gay, bisexual men and other men who have sex with men
In 2014, an estimated 45,000 (CrI 41,900-49,500) MSM were living with HIV in the UK.
This has increased year on year from 38,400 (CrI 34,300-43,800) in 2010 and 43,000
(CrI 40,000-47,300) in 2013. This is largely due to reductions in premature death from
HIV as a result of effective antiretroviral therapy (ART), as well as continued HIV
transmission. Corresponding estimates of the number of MSM living with undiagnosed
HIV have decreased over time from 8,500 (CrI 4,600-13,900, (22%)) in 2010 to 6,500
(CrI 3,500-10,900, (14%)) in 2014. While there is evidence that the prevalence of
undiagnosed HIV in MSM has declined since 20103
, there is no evidence that this
decline continued between 2013 and 2014 (Figure 2).
Figure 2. Estimated number of undiagnosed HIV infections by exposure
categories1
over time in the UK (all ages); 2010-2014
1
Heterosexual men and women include black African heterosexuals. Lines through the bars represent 95% credible
intervals
3
A Bayesian evidence synthesis model of HIV prevalence in the UK over time shows that among 15-59 year olds
there is an 89% probability that the proportion, and a 74% probability that the number of MSM living with undiagnosed
HIV is smaller in 2014 than in 2010, with a 56% and 55% chance that the proportion/number respectively are smaller
in 2014 than in 2013.
10. HIV in the UK – Situation Report 2015: Incidence, prevalence and prevention
10
Less than half (45%, 20,200) of all MSM living with HIV were London residents . In the
UK in 2014, the estimated HIV prevalence among MSM aged 15-44 was one in 20 (48.7
MSM (CrI 41.2-58.1) per 1,000). This was higher in London, where one in 11 MSM
(89.7 per 1,000 (CrI 65.9-122.6)) were living with HIV compared to one in 28 (35.6 per
1,000 (CrI 28.5-43.7)) in England and Wales outside of London.
A second methodology to estimate the number of undiagnosed HIV using CD4 back-
calculation predicted that 7,100 (CrI 5,500-9,200) MSM aged 15 and over were living
with undiagnosed HIV in England and Wales in 2014, with a decline from from 9,100
(CrI 8,700-9,500) in 2010 (Figure 4). The number and trend are broadly comparable
with the MPES estimates of undiagnosed infection (Figure 1 and Appendix 1), though
the credible intervals for both methods are wide, especially in the most recent period.
The five-year decreasing trend in the number of MSM living with undiagnosed HIV
infections was geographically consistent, seen in London (3,400 (CrI 1,300-7,200) in
2010 compared to 2,400 (CrI 800-5,800) in 2014) (Figure 3) and outside London in
England and Wales (3,900 (CrI 1,400-7,900) in 2010 and 2,800 (CrI 1,000-5,700) in
2014). This decline coincided with increases in HIV testing among MSM attending STI
services (see HIV Testing section). In 2014, the undiagnosed HIV prevalence among
MSM aged 15-44 was 13.3 per 1,000 in London (CrI 4.1-35.2) compared to 5.9 per
1,000 (CrI 1.8-10.8) outside of London.
New diagnoses among MSM have continued to rise, with 3,360 men4
newly diagnosed
in 2014, the largest number ever recorded (up from 3,270 in 2013 and 2,860 in 2010),
accounting for more than half of all new HIV diagnoses (6,151) [1].
Two-thirds of MSM were aged between 25-44, with 6% aged 55 years old and over at
the time of their new diagnosis. The median age at diagnosis in 2014 was 33 years old,
and this has been stable over time (35 in 2005). Over half (51%) of all new diagnoses in
MSM in the UK were made in London. Four in five MSM newly diagnosed with HIV were
white (81%), with 2% Black African, 2% Black Caribbean and 14% described as
Other/mixed. The majority (60%) were born in the UK with 20% from the rest of Europe,
3% born in Africa and 6% in Asia.
4
Figures adjusted for missing by re-allocating across exposure groups according to known distributions
11. HIV in the UK – Situation Report 2015: Incidence, prevalence and prevention
11
Figure 3. Estimated number of undiagnosed HIV infections by exposure groups1
over time in London (all ages); 2010-2014
1
Heterosexual men and women include black African heterosexuals. Lines through the bars represent 95% credible
intervals
In 2014, 64% of MSM newly diagnosed with HIV in England, Wales and Northern
Ireland were tested for recent infection using the recent infection testing algorithm
(RITA) 5
and of these 32% (595/1,876) were likely to have acquired their infection in the
previous six months (Appendix 3). This has steadily risen from 23% (360/1,560) in
2011, through 27% (430/1,620) in 2012 and 30% in 2013. RITA testing coverage was
higher in MSM compared to heterosexuals (53%) or PWID (43%).
5
The Recent Infection Testing Algorithm (RITA) incorporates results from an HIV antibody assay modified for the
determination of HIV avidity as well as clinical biomarkers to distinguish recently acquired from long-standing HIV
infection.
12. HIV in the UK – Situation Report 2015: Incidence, prevalence and prevention
12
Figure 4. Back-calculation estimate of HIV incidence and prevalence of
undiagnosed HIV infection1
among MSM aged 15 and over: England and Wales
2005-2014
The rise in new HIV diagnoses and in the proportion of these that were recent infections
among MSM may be explained by both increases in HIV testing ongoing HIV
transmission. The CD4 back-calculation model estimates that over the past decade
approximately 2,600 MSM have acquired HIV each year in England and Wales (Figure
4), with suggestions of a small sequential rise in 2013 (2,700 (CrI 1,900-3,900)) and
2014 (2,800 (CrI 1,600-4,800)).
Despite improved HIV testing coverage in STI clinics the number of for MSM diagnosed
late with a CD4<350 remains high with only a slight decline over the past 10 years from
1,131 in 2005 to 974 in 2014 (adjusted for missing CD4 count) (Figure 5).
13. HIV in the UK – Situation Report 2015: Incidence, prevalence and prevention
13
Figure 5. Number1
of people diagnosed at a late stage of infection (CD4<350
copies/mL)2
by exposure category: UK, 2004-2014
14. HIV in the UK – Situation Report 2015: Incidence, prevalence and prevention
14
Heterosexual men and women
An estimated 21,300 (CrI 18,900-25,100) men and 32,700 (CrI 30,000-37,400) women
who acquired HIV through heterosexual sex were living with HIV in the UK in 2014, of
whom over half (55%, of men (9,900/21,300) and 62% of women (20,100/32,700)) were
of black African ethnicity. Numbers of heterosexual men and women and black African
men and women living with HIV have continued to rise since at least 2010, from 19,800
(CrI 17,200-23,400) and 29,000 (CrI 26,300-32,400) respectively.
Among all heterosexuals living with HIV in 2014, an estimated 21% (11,200 (CrI 6,200-
18,900) were unaware of their infection compared to 20% (11,100 (CrI 5,400-18,400,
20%) in 2013 and 27% (13,400 (CrI 8,100-20,200) in 2010.
In 2014, 24% of all heterosexual men (5,100, CrI 2,800-8,900) living with HIV were
unaware of their HIV infection compared to 18% of heterosexual women (18%, 6,000,
CrI 3,400-10,500). This difference is largely due to the effectiveness of the UK antenatal
screening programme. While there is considerable uncertainty in the estimates,
reflected in the wide credible intervals, a trend analysis shows evidence that there is
likely to have been a reduction in undiagnosed HIV among heterosexual men between
2010 and 2014, though less evidence for one in women6
.
Among the black African population, the proportion and number of PLWH estimated to
be undiagnosed were 16% (CrI 3%-32%), 1,500) among men and 12% (CrI 3%-26%),
2,400) among women in 2014. While the overwhelming majority of black African
heterosexual men and women living in the UK do not have HIV, in 2014 among 15-44
year olds, an estimated 17.9 per 1,000 black African heterosexual men (CrI 14.6-23.3
per 1,000) and 43.7 per 1,000 black African women (CrI 38.4-52.8) were living with HIV
compared to 0.5 (CrI 0.4-0.6) per 1,000 non-black African and 0.7 (CrI 0.6-0.8) per
1,000 non-black African women.
In 2014, heterosexual men and women were estimated to be twice as likely to have
undiagnosed HIV if they lived outside London (24% (CrI 11%-37%), undiagnosed 7,400
people) compared to in London (12% (CrI 6%-26%) undiagnosed, 2,400 people). This
trend was consistent for men and women of black African ethnicity. HIV testing
coverage in STI clinics among heterosexuals lags behind those among MSM across all
of England (see HIV testing section for more details).
In 2014, 2,490men (1,065) and women (1,425) were diagnosed with HIV infection
through heterosexual sex [1]. New diagnoses among heterosexual men and women
6
76% probability of a decrease in the number of heterosexual men living with undiagnosed HIV between 2010 and
2014 in the UK and a 65% probability of the same for undiagnosed women
15. HIV in the UK – Situation Report 2015: Incidence, prevalence and prevention
15
have declined by almost half since 2005 (4,840), largely due to a reduction in new
diagnoses among people born in sub-Saharan Africa.
In 2014, 51% of heterosexual men living with HIV were aged 25-44 years at diagnosis
compared to 60% of women, while 18% and 9% were over 55 respectively. The median
age at HIV diagnosis for heterosexuals has increased steadily over time, from 34 (32 in
women, 37 in men) in 2005 to 40 in 2014 (37 in women and 43 in men).
Among the 1108 heterosexuals diagnosed in 2014 who had a RITA test performed, one
in ten (10% (112/1,108) were probably recently acquired, with similar proportions
among men (59/499 (12%)) and women (53/609 (9%)). There were apparent
differences in recency by ethnicity however with 6.4% (34/529, CI 4.5-8.9%) among
black Africans compared to 17.4% (64/368, CI 13.7%-21.7%) among people of white
ethnicity, though there may be sampling and subtype biases. Although RITA test
coverage was lower in heterosexuals than among MSM and thus difficult to compare, a
lower proportion of heterosexuals had evidence of recent infection compared to MSM.
While there have been declines over time in the number of late diagnoses among
heterosexual men (1,224 in 2005 to 643 in 2014) and women (1,905 in 2005 to 738 in
2014) (Figure 5), the proportion diagnosed late remains over 50% in both sexes with the
median CD4 at diagnosis staying low at 280 cells/mL in heterosexual men and 335
cells/mL in women in 2014, emphasising the need to further improve HIV testing
availability and uptake.
People who inject drugs
In 2014, an estimated 2,160 people who inject drugs (PWID) were living with HIV in the
UK (1,500 men and 650 women), of whom 11% (CrI 7%-19%) were unaware of their
HIV status. The estimated prevalence of HIV among this population in the UK was 2.2
per 1,000 aged 15-44 in 2014.
A low and stable number of people (150/6,151 (2%)) were diagnosed with HIV acquired
through shared use of injecting drug equipment in 2014, of which 101 were men and 49
women and most white (82%). Almost one third (30%) of these diagnoses were made in
LondonThree quarters (73%) of new diagnoses among PWID were made in people
aged 25-44 with 6% aged 55 or above.
A high proportion of PWID newly diagnosed with HIV in 2014, were already at a late
stage of infection (66/101 (65%)) and only 4% (2/49) of samples tested through the
RITA algorithm were indicative of recent infection.
16. HIV in the UK – Situation Report 2015: Incidence, prevalence and prevention
16
HIV Testing
HIV testing in STI services
In England, 1.43 million people were reported to have attended an STI (also known as
GUM) clinic in 2014, more than in 2013 (1.37 million). The proportion of eligible people
tested for HIV infection (coverage) was 69% (991,816/1,439,212), a slight decrease
from 71% in 2013.
HIV testing coverage remained highest among MSM (87%, 90,719/104,028), followed
by heterosexual men (77%, 382,743/497,455) and women (62%, 504,249/814,459).
Though overall increases in testing coverage in MSM and heterosexual men have
continued since 2009 (rising from 78% in MSM and 72% in heterosexual men in 2009),
coverage in women has decreased from 67% in 2013. This is despite an increase in
eligible women testing (up from 482,443 in 2013) and may be due to attendances at
integrated sexual and reproductive health clinics in which the population of women
being seen may be at lower HIV risk (Appendices 4 and 5).
There were 179 of 223 (80%) STI clinics in England where HIV testing coverage
reached at least 80% among MSM attendees, consistent with BASHH
recommendations for STI testing in MSM [5]. Of these, 44 clinics achieved optimal (90%
or greater) testing coverage in eligible MSM attendees (Figure 6). However, coverage
was lower among heterosexual men and women, where 85% (190/223) of clinics fell
below 80% (Figure 7). In every PHE centre area of the country there were marked
differences between local services in the levels achieved for HIV test coverage.
Despite improved coverage for MSM among STI clinic attendees, continued efforts to
further increase HIV testing are needed, in line with national testing guidance [5-
7]. Expanded HIV testing outside of STI services should also be implemented in order to
increase accessibility among populations not regularly presenting to STI clinics. STI
clinic data from England in 2014 indicate that less than one quarter of people of black
African or black British ethnicity presented to the same STI clinic at least once in the
previous five years.
New HIV diagnoses in STI clinic attendees
In 2014, a total of 4,155 people were diagnosed with HIV through testing at STI clinics
(3,247 men and 907 women). The majority of new diagnoses were found in men (78%),
with MSM comprising over half (55%, 2,276/4,155) of all new diagnoses in 2014. The
largest proportions of new diagnoses were made in white (55%), followed by black or
17. HIV in the UK – Situation Report 2015: Incidence, prevalence and prevention
17
black British ethnic groups (22%). No ethnicity data was available for 299 (7%) of all
new diagnoses.
Nearly two-thirds (63%, 2,628/4155) of all new HIV diagnoses in STI clinics were
reported in people aged 25-44. Over 24% (1,004/4155) of all diagnoses occurred in
people over the age 45, while 77 diagnoses were found in those 65 and older. The age
distribution of new HIV diagnoses differed between men and women. New diagnoses in
men were highest in those aged 25-34 (37%, 1,217/3,247) and by those 35-44 (27%,
880/3,247). Similarly, the greatest proportions of new diagnoses in women were
reported among those aged 25-34 (30%, 268/907) and 35-44 (29%, 262/907). Of those
newly diagnosed in STI clinics over the age of 45, 74% were male.
Of the 4,155 people diagnosed with HIV in STI clinics in 2014, 3654 (88%) had not had
a test at the same clinic within the preceding 43 to 365 day period. Of the 501 (12%)
that had had an HIV test reported within this time period in the same clinic, 172 people
had tested twice, 51 tested three times, 13 tested four times and two tested five times.
For people who had tested at least once in the previous 43 to 365 day period, the mean
time to re-test was 175 days.
Partner notification in STI services
Partner notification (PN) – whereby partners of those newly diagnosed with HIV are
contacted for testing – is an effective way of reaching people previously undiagnosed
with HIV infection. The BASHH recommends that every individual diagnosed with HIV at
an STI clinic is offered PN [8].
In England, 2,225 people reported attending a STI clinic service following partner
notification for HIV in 2014 (Appendix 6). Assuming the 4,155 people newly diagnosed
with HIV in STI clinics were all offered PN, this gives a PN ratio of 0.54. Of all the
patients who attended through PN, an HIV test was reported for 1,830 (82.2%) and, of
these, 102 (5.6%) were newly diagnosed with HIV. Positivity was slightly higher among
MSM (6.4%) compared to heterosexual men (5.5%). There was also variation by gender
and age: positivity was higher in men aged over 65 years (12.5%) and women aged 45-
64 (6.6%).
18. HIV in the UK – Situation Report 2015: Incidence, prevalence and prevention
18
Figure 6. Variation in HIV test coverage1,2
between STI clinics in England, by PHE
centre, among MSM attendees: England, 2014
19. HIV in the UK – Situation Report 2015: Incidence, prevalence and prevention
19
Figure 7. Variation in HIV test coverage1,2
between STI clinics in England, by PHE
centre, among heterosexual attendees: England, 2014
20. HIV in the UK – Situation Report 2015: Incidence, prevalence and prevention
20
HIV testing through self (home)-sampling or self (home)-testing
Increased HIV testing, especially in the most at-risk populations, is a central component
of any HIV prevention strategy. To achieve this end, innovations in both HIV self-
sampling and self-testing appear promising. HIV self-sampling involves the request of a
free sampling pack online, sampling home (a finger-prick blood test or an oral swab),
and posting the sample to a laboratory for HIV testing, with a result texted or telephoned
within 48 hours. Self-testing involves the purchasing a test-kit, sampling and testing at
home with an immediate result. It is now lawful to sell and advertise the sale of HIV self-
testing kits in England, Scotland and Wales, and self-testing kits are available for
purchase.
PHE has supported two successful pilot national HIV self-sampling services (Terrence
Higgins Trust/HIV Prevention England and Dean Street At-Home). During National HIV
Testing Weeks in 2013 and 2014, people were able to order online free self-sampling
kits to use at home. The success of these service pilots resulted in the establishment of
a national self-sampling service co-commissioned by PHE and 89 collaborating local
authorities. This service, for those at high HIV risk, began in November 2015 as part of
‘National HIV Testing Week’.
Antenatal screening
In 2014, the HIV screening coverage of pregnant women in England was 97% with over
690,000 women tested, and 1.5 women per 1,000 (1,018/693,570) testing HIV positive.
An estimated 22% of these women were diagnosed for the first time as a direct result of
their 2014 pregnancy screening, the remaining women had been diagnosed prior to
their 2014 pregnancy.
Between 2006 and 2014, in the UK as a whole, the transmission rate for the
approximately 11,000 children born to women living with HIV infection diagnosed prior
to delivery was well under 1% [9]; another 75 infants were also born and diagnosed with
perinatally acquired HIV whose mothers were not diagnosed prior to delivery [10].
HIV screening in blood donors
In 2014, 13 donors tested positive for HIV infection at screening, representing 0.6
detected infections per 100,000 donations. Where known, HIV infection was mostly
acquired in the UK (7/13). Six of the 13 donors were men and three reported sex with
other men. One was compliant with the 12 month MSM blood donor deferral policy and
had not had sex with another man in the last year and had not been tested in any other
setting during that time. Eight donors (three men, five women) were repeat donors, all
acquired HIV within three years following their previous negative donation and two had
avidity results that suggested recent HIV infection prior to their HIV diagnosis [11].
21. HIV in the UK – Situation Report 2015: Incidence, prevalence and prevention
21
HIV Prevention
Pre-exposure prophylaxis (PrEP)
HIV Pre Exposure Prophylaxis (HIV – PrEP) is the use of antiretroviral agents by people
who do not have HIV prior to a potential exposure to HIV to prevent acquisition of
infection. Worldwide a number of research studies in different populations have shown
that consistent use of HIV-PrEP can be an efficacious and effective prevention
intervention. Two European studies of oral PrEP using a combination of tenofovir and
emtricitabine coformulated as Truvada (t) among men who have sex with men (PROUD
trial [12] in the UK and the IPERGAY trial [13] in France) have reported during 2015.
Both trials demonstrated a reduction in HIV acquisition of 86% in intent to treat
analyses. Existing and emerging data suggest that HIV – PrEP has the potential, within
a combination prevention approach, to have a significant role in the control of HIV
transmission.
In England use of anti-retroviral drugs, whether for treatment or prevention, is
designated as a specialised service that is commissioned by NHS England. PHE is
actively involved in supporting NHS England and local authorities as they prepare to
make commissioning decisions about PrEP. Working within the PrEP Policy Working
Group (of NHS England’s Clinical Reference Group) for HIV, PHE is supporting NHS
England’s policy development through the delivery of data and intelligence, which
includes a comprehensive evidence review and health economic analyses.
Impact of treatment on HIV prevention in the UK
People on effective ART with an undetectable viral load are very unlikely to pass on HIV
to sexual partners [14-16].
In the UK, free and accessible HIV treatment and care has resulted in large-scale
treatment coverage: in 2014, an estimated 75% of all PLWH (diagnosed and
undiagnosed) were treated and 70% of all PLWH (72,800/103,700) had an undetectable
viral load (less than 200 copies/UL) (Figure 8). This figure is close to the ambitious
UNAIDS target of 73% of all PLWH being virologically suppressed, as laid out in the 90-
90-90 goals (90% of people living with HIV being diagnosed, 90% diagnosed on ART
and 90% viral suppression for those on ART by 2020) [17].
The number and proportion of people initiating ART at CD4 counts>350 cells/mm3
has
increased between 2010 and 2014 (Figure 9). This is particularly seen for those with a
CD4>500 cells/mm3
in which group 1,700 people (31% of all initiations) initiated ART in
2014 compared to 600 (11%) in 2010. This may reflect earlier prescribing and uptake of
22. HIV in the UK – Situation Report 2015: Incidence, prevalence and prevention
22
ART to prevent HIV transmission as per British HIV Association (BHIVA) guidelines [18,
19].
Figure 8. The UK HIV treatment cascade, all ages: 2014
Figure 9. Number1
of patients starting ART by CD4 count at initiation2
: UK, 2010-
2014
23. HIV in the UK – Situation Report 2015: Incidence, prevalence and prevention
23
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diagnoses, treatment and care in the UK 2015 report: data to end 2014. October 2015. Public Health
England, London.
2. Estimates of human immunodeficiency virus prevalence and proportion diagnosed based on
Bayesian multiparameter synthesis of surveillance data. Goubar A et al. Journal of the Royal
Statistical Society, Jun 2008. DOI: 10.1111/j.1467-985X.2007.00537.x
3. Sonnenberg P, Clifton S, Beddows S, Field N, Soldan K, Tanton C, Mercer CH, da Silva FC,
Alexander S, Copas AJ, Phelps A, Erens B, Prah P, Macdowall W, Wellings K, Ison CA, Johnson AM.
Prevalence, risk factors, and uptake of interventions for sexually transmitted infections in Britain:
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30;382(9907):1795-806.
4. British Association for Sexual Health. BASHH Recommendations for Testing for Sexually Transmitted
Infections in Men who have Sex with Men Accessed on: 16 November 2015. Available at:
http://www.bashh.org/documents/BASHH%20Recommendations%20for%20testing%20for%20STIs%
20in%20MSM%20-%20FINAL.pdf
5. Addressing Late HIV Diagnosis through Screening and Testing: An Evidence Summary, Public Health
England, April 2014. Accessed 18 October 2015. Available at:
http://www.bashh.org/documents/HIV%20Screening%20and%20Testing_Evidence%20Summary_Ap
ril%202014.pdf
6. HIV Testing, 2014. Guideline LGB21. National Institute for Clinical Excellence. Available at:
https://www.nice.org.uk/advice/lgb21/chapter/What-NICE-says#nice-recommendations. Accessed 16
October 2015.
7. UK National Guidelines for HIV Testing 2008. Prepared by BHIVA, BASHH and BIS. Available at:
http://www.bhiva.org/documents/guidelines/testing/glineshivtest08.pdf.
8. McClean H, Radcliffe K, Sullivan A and Ahmed-Jushuf I. 2012 BASHH statement on partner
notification for sexually transmissible infections. International Journal of STD & AIDS 2013;
doi:10.1177/0956462412472804. Available at:
http://www.bashh.org/documents/2012%20Partner%20Notification%20Statement.pdf
9. Townsend CL, Byrne L, Cortina-Borja M, Thorne C, de Ruiter A, Lyall H, Taylor GP, Peckham CS,
Tookey PA. Earlier initiation of ART and further decline in mother-to-child HIV transmission rates,
2000-2011. AIDS 2014,28:1049-1057
10. Obstetric and paediatric HIV surveillance data from the UK and Ireland. NSHPC 2015. Population
Policy and Practice Programme, UCL Institute of Child Health London. Available at:
www.ucl.ac.uk/nshpc
11. Safe Supplies: Uncovering Donor Behaviour. Annual Review from the NHS Blood and
Transplant/Public Health England Epidemiology Unit, 2014. London, 2015.
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http://www.gov.uk/government/collections/bloodborne-infections-in-blood-and-tissuedonors-bibd-
guidance-data-and-analysis
12. Pre-exposure prophylaxis to prevent the acquisition of HIV-1 infection (PROUD): effectiveness results
from the pilot phase of a pragmatic open-label randomised trial. McCormack S et al. Lancet,
published online 09 Sept 2015. Available at:
http://www.thelancet.com/journals/lancet/article/PIIS0140-6736(15)00056-2/abstract.
13. On Demand PrEP With Oral TDF-FTC in MSM: Results of the ANRS Ipergay Trial. Molina JM et al.
Presented at CROI, Feb 23-26 2015, Washington. Abstract 23LB. Available at:
http://www.croiconference.org/sessions/demand-prep-oral-tdf-ftc-msm-results-anrs-ipergay-trial
14. Prevention of HIV-1 infection with early antiretroviral therapy. Cohen MS et al. NEJM. 2011 Aug 11;
365(6):493-505. doi: 10.1056/NEJMoa1105243. Epub 2011 Jul 18.
15. British HIV Association guidelines for the treatment of HIV-1 positive adults with antiretroviral therapy
2015. BHIVA writing group. Accessed 16
th
Nov 2015.
http://www.bhiva.org/documents/Guidelines/Treatment/2015/2015-treatment-guidelines.pdf
16. HIV transmission risk through condomless sex if the HIV positive partner is on suppressive ART:
PARTNER study A Rodger, V Cambiano, T Bruun, P Vernazza, S Collins, V Estrada, J Van Lunzen,
GM Corbelli, AM Geretti, D Asboe, P Viciano, F Gutiérrez, C Pradier, K Westling, R Weber, H Furrer,
J Prins, J Gerstoft, A Phillips and J Lundgren for the PARTNER Study Group. Presented CROI 2014.
Slides available at http://www.cphiv.dk/portals/0/files/CROI_2014_PARTNER_slides.pdf
17. 90-90-90 An ambitious treatment target to help end the AIDS epidemic. Accessed 16
th
Nov 15.
Available at http://www.unaids.org/sites/default/files/media_asset/90-90-90_en_0.pdf
18. BHIVA guidelines for the treatment of HIV-1 positive adults with antiretroviral therapy 2015. Accessed
on: 16 Nov 2015. http://www.bhiva.org/documents/Guidelines/Treatment/consultation/150621-BHIVA-
Treatment-GL-Final-draft-for-consultation.pdf
19. BHIVA treatment guidelines British HIV Association. Treatment of HIV-1 positive adults with
antiretroviral therapy 2012 (updated November 2013). Accessed on: 24 October 2015. Available at:
http://www.bhiva.org/documents/Guidelines/Treatment/2012/hiv1029_2.pdf
20. NHS England’s response to a public consultation “investing in specialised services”, June
2015. https://www.england.nhs.uk/2015/07/02/annual-investment-decisions
21. Promoting the health and wellbeing of gay, bisexual and other men who have sex with men.
https://www.gov.uk/government/publications/promoting-the-health-and-wellbeing-of-gay-bisexual-and-other-
men-who-have-sex-with-men
25. HIV in the UK – Situation Report 2015: Incidence, prevalence and prevention
25
Appendices
Appendix 1: Estimated number1
of people living with HIV (both diagnosed and
undiagnosed) by exposure category: UK, 2014
Number
diagnosed
Number
undiagnosed
Total % Undiagnosed
(credible interval)2
(credible interval)2
(credible interval)2
(credible interval)2
38,480 6,490 44,980 14%
(37,770, 39,200) (3,529, 10899) (41,930, 49,460) (8, 22%)
1,915 243 2,162 11%
(1,713, 2,039) (135, 440) (1,918, 2,405) (7, 19%)
42,880 11,160 54,050 21%
(42,040, 43,790) (6,240, 18,920) (49,010, 61,920) (13, 31%)
16,190 5,100 21,290 24%
(15,880, 16,510) (2,750, 8,839) (18,910, 25,050) (15, 35%)
8,312 1,530 9,845 16%
(8,114, 8,510) (291, 3,884) (8,586, 12,220) (3, 32%)
7,878 3,570 11,445 31%
(7,697, 8,068) (1,815, 6,982) (9,671, 14,880) (19, 47%)
26,690 6,000 32,680 18%
(26,090, 27,310) (3,369,10,509) (29,950, 37,350) (11, 28%)
17,730 2,380 20,120 12%
(17,300, 18,180) (479, 6,090) (18,130, 23,900) (3, 26%)
8,960 3,620 12,560 29%
(8,709, 9,220) (1,851, 5,535) (10,790, 14,540) (17, 38%)
85,600 18,090 103,700 17%
(84,140, 87,110) (12,100, 26,880) (97,500, 112,700) (12, 24%)
2
Lower bound, upper bound.
Women excluding
black Africans
Total3
1
National estimates of the number of people living with HIV in the UK are obtained from the multi-parameter statistical model fitted to a range of
surveillance and survey data.
3
Numbers may not add to total due to rounding and exclusion of data relating to HIV acquired through mother-to-child transmission and blood
related products.
Exposure category
Men who have sex with men
People who inject drugs
Heterosexuals
Men
Black African
ethnicity
Men excluding
black Africans
Women
Black African
ethnicity
26. HIV in the UK – Situation Report 2015: Incidence, prevalence and prevention
26
Appendix 2: Comparison of estimated number of people living with HIV (both diagnosed and undiagnosed) using
revised methods: UK, 2010, 2013 and 2014
Total % Undiagnosed Total % Undiagnosed Total % Undiagnosed
(credible interval)
2
(credible interval)
2
(credible interval)
2
(credible interval)
2
(credible interval)
2
(credible interval)
2
44,980 14% 42,990 16% 38,350 22%
(41,930, 49,460) (8, 22%) (39,950, 47,270) (9, 23%) (34,290, 43,750) (13, 32%)
2,162 11% 2,356 10% 2,499 27%
(1,918, 2,405) (7, 19%) (2,132, 2,564) (6, 16%) (2,133, 2.955) (17. 37%)
54,050 21% 52,050 21% 48,870 27%
(49,010, 61,920) (13, 31%) (47,360, 59,980) (13, 31%) (43,550, 55,840) (19, 37%)
21,290 24% 21,190 25% 19,820 32%
(18,910, 25,050) (15, 35%) (18,970, 24,930) (17, 36%) (17,220, 23,430) (22, 43%)
9,845 16% 9,869 15% 9,095 17%
(8,586, 12,220) (3, 32%) (8,777, 12,060) (5, 30%) (7,854, 11,150) (4, 32%)
11,445 31% 11,321 34% 10,725 45%
(9,671, 14,880) (19, 47%) (10,193, 12,870) (22, 50%) (9,366 , 12,280) (33, 61%)
32,680 18% 30,860 18% 29,050 24%
(29,950, 37,350) (11, 28%) (28,390, 35,050) (12, 28%) (26,330, 32,410) (16, 32%)
20,120 12% 19,310 11% 17,820 12%
(18,130, 23,900) (3, 26%) (17,690, 22,540) (3, 24%) (16,040, 20,730) (3, 25%)
12,560 29% 11,550 31% 11,230 43%
(10,790, 14,540) (17, 38%) (10,700, 12,510) (18, 40%) (10,290, 11,680) (31, 52%)
103,700 17% 99,960 18% 91,940 25%
(97,500, 112,700) (12, 24%) (93,819, 108,200) (13, 24%) (85,000, 99,980) (19, 31%)
1
In the revised method, African people are defined by their reported ethnicity, the previous method defined through country of birth.
2
Lower bound, upper bound.
Total3
3
Numbers may not add to total due to rounding and exclusion of data relating to HIV acquired through mother-to-child transmission and blood related
Heterosexuals
Men
Black African
ethnicity
Men excluding black
Africans
Women
Black African
ethnicity
Women excluding
black Africans
People who inject drugs
2014 estimates (revised method) 2013 estimates (revised method) 2010 estimates (revised method)
Exposure category1
Men who have sex with men
27. HIV in the UK – Situation Report 2015: Incidence, prevalence and prevention
27
Appendix 3: Number and proportion of likely recently acquired infections at diagnosis (ascertained through the
Recent Infection Testing Algorithm) by exposure category and age group: England, Wales and Northern Ireland,
20141, 2, 3
15-24 25-34 35-49 50+ Total
Recent infections 112 280 156 47 595
Number RITA tested 292 778 595 211 1,876
% 38% 36% 26% 22% 32%
(95% CI) (33-44) (33-39) (23-30) (17-28) (30-34)
Recent infections 10 17 20 12 59
Number RITA tested 27 98 225 149 499
% 37% 17% 9% 8% 12%
(95% CI) (19-58) (10-26) (6-13) (4-14) (9-15)
Recent infections 13 21 10 9 53
Number RITA tested 70 193 234 112 609
% 19% 11% 4% 8% 9%
(95% CI) (10-30) (7-16) (2-8) (4-15) (7-11)
Recent infections 23 38 30 21 112
Number RITA tested 97 291 459 261 1,108
% 24% 13% 7% 8% 10%
(95% CI) (16-33) (9-17) (4-9) (5-12) (8-12)
Recent infections 142 331 189 71 733
Number RITA tested 424 1,133 1,150 516 3,223
% 33% 29% 16% 14% 23%
(95% CI) (29-38) (27-32) (14-19) (10-17) (21-24)
1
Ascertained bv the Recent Infection Testing Algorithm (RITA)
2
Overall, nearly 50% of new HIV diagnoses had a test for recent infection and this was similar across exposure categories .
Note: Appendices show actual numbers. Numbers presented in text are rounded.
3
Data to end August 2014. From September 1st
2013 a new assay to test for recent infection was introduced which uses a
different algorithm to classify recent infection.
Total
Exposure category
Men who have sex
with men
Heterosexual men
Heterosexual women
All Heterosexuals
28. HIV in the UK – Situation Report 2015: Incidence, prevalence and prevention
28
Appendix 4: HIV test coverage1
by gender, male sexual orientation, and age
group: England, 2014
Age group
<15 546 338 196 62 36
15-19 43,664 39,330 31,338 90 72
20-24 131,903 122,138 103,321 93 78
25-34 187,779 173,351 148,627 92 79
35-44 74,062 66,803 56,372 90 76
45-64 53,415 46,604 38,993 87 73
65+ 5,881 4,647 3,734 79 63
Subtotal3
497,455 453,399 382,743 91 77
<15 37 27 22 73 59
15-19 4,924 4,474 4,269 91 87
20-24 19,832 18,350 17,731 93 89
25-34 39,347 36,355 35,008 92 89
35-44 21,122 19,119 18,178 91 86
45-64 16,637 14,654 13,727 88 83
65+ 2,063 1,815 1,718 88 83
Subtotal3
104,028 94,862 90,719 91 87
<15 834 494 278 59 33
15-19 50,790 45,253 36,681 89 72
20-24 157,065 144,611 124,509 92 79
25-34 235,120 215,849 188,965 92 80
35-44 98,745 88,385 76,615 90 78
45-64 72,975 63,045 54,205 86 74
65+ 8,262 6,628 5,589 80 68
Subtotal3
624,485 564,894 487,359 90 78
<15 4,848 2,965 1,480 61 31
15-19 134,081 107,956 70,861 81 53
20-24 237,934 202,153 154,348 85 65
25-34 272,841 229,205 178,978 84 66
35-44 101,513 81,948 61,614 81 61
45-64 58,924 46,520 35,163 79 60
65+ 3,067 1,794 1,333 58 43
Subtotal3
814,459 673,318 504,249 83 62
<15 5,682 3,459 1,758 61 31
15-19 184,901 153,238 107,564 83 58
20-24 395,069 346,826 278,910 88 71
25-34 508,065 445,156 368,028 88 72
35-44 200,295 170,366 138,254 85 69
45-64 131,924 109,587 89,389 83 68
65+ 11,331 8,424 6,924 74 61
Total3
1,439,212 1,238,462 991,816 86 69
2
Defined as a visit to an STI clinic including all subsequent STI attendances during the following six weeks.
3
Include individuals without age reported.
Note: Appendices show actual numbers. Numbers presented in text are rounded.
4
Include heterosexual women and women who have sex with women. In text, the 67% (470,760/705,690) coverage was among
heterosexual women.
HIV test
STI clinic
attendees2
Offered Tested Offered % Coverage %
1
HIV test coverage measures the percentage of eligible new GUM attendees in whom a HIV test was accepted. An eligible new GUM
attendee is defined as a patient attending a GUM clinic at least once during a calendar year. People known to be HIV positive, or for
whom a HIV test was not appropriate, are excluded. HIV test uptake (in Appendix 14) measures the number of eligible new GUM
episodes where a HIV test was accepted as a percentage of those where a HIV test was offered. An eligible new GUM episode is
defined as a visit to a GUM clinic including all subsequent GUM attendances in the following six weeks. Attendances by known HIV
positive patients, or where a HIV test was not appropriate, are excluded.
Women4
Total
Gender
Men
Heterosexual
Menwhohavesex
withmen
(by sexual
orientation)
Allmen
29. HIV in the UK – Situation Report 2015: Incidence, prevalence and prevention
29
Appendix 5: HIV test uptake1
by gender, male sexual orientation, and age group:
England, 2014
Age group
<15 639 382 222 60 58
15-19 51,448 44,392 34,515 86 78
20-24 158,563 138,809 114,084 88 82
25-34 222,430 193,974 162,339 87 84
35-44 87,825 73,519 60,709 84 83
45-64 64,348 50,770 41,646 79 82
65+ 7,657 5,096 4,017 67 79
Subtotal3
593,056 507,067 417,638 86 82
<15 54 35 29 65 83
15-19 7,114 5,777 5,461 81 95
20-24 28,924 24,523 23,397 85 95
25-34 58,667 50,033 47,621 85 95
35-44 31,537 26,102 24,592 83 94
45-64 24,293 19,080 17,643 79 92
65+ 3,071 2,317 2,150 75 93
Subtotal3
153,699 127,900 120,925 83 95
<15 1,004 567 312 56 55
15-19 60,958 51,717 41,102 85 79
20-24 193,315 167,757 141,148 87 84
25-34 289,720 250,473 215,523 86 86
35-44 123,254 102,208 87,449 83 86
45-64 91,900 71,719 60,822 78 85
65+ 11,088 7,590 6,307 68 83
Subtotal3
771,845 652,557 553,086 85 85
<15 6,637 3,730 1,750 56 47
15-19 179,567 133,491 81,747 74 61
20-24 304,128 240,858 175,125 79 73
25-34 339,249 266,325 199,978 79 75
35-44 123,964 92,470 67,165 75 73
45-64 71,364 51,346 37,929 72 74
65+ 4,001 1,915 1,398 48 73
Subtotal3
1,029,945 790,667 565,411 77 72
<15 7,641 4,297 2,062 56 48
15-19 240,556 185,237 122,871 77 66
20-24 497,516 408,679 316,327 82 77
25-34 629,074 516,901 415,586 82 80
35-44 247,259 194,712 154,640 79 79
45-64 163,290 123,087 98,772 75 80
65+ 15,091 9,507 7,707 63 81
Total3
1,802,068 1,443,478 1,118,707 80 78
2
Defined as a visit to an STI clinic including all subsequent STI attendances during the following six weeks.
3
Include individuals without age reported.
Note: Appendices show actual numbers. Numbers presented in text are rounded.
1 HIV test uptake measures the number of eligible new GUM episodes where a HIV test was accepted as a percentage of those where
a HIV test was offered. An eligible new GUM episode is defined as a visit to a GUM clinic including all subsequent GUM attendances in
the following six weeks. Attendances by known HIV positive patients, or where a HIV test was not appropriate, are excluded. HIV test
coverage (in Appendix 13) measures the percentage of eligible new GUM attendees in whom a HIV test was accepted. An eligible new
GUM attendee is defined as a patient attending a GUM clinic at least once during a calendar year. People known to be HIV positive, or
for whom a HIV test was not appropriate, are excluded.
HIV test
Uptake %
Heterosexual
Menwhohavesex
withmen
Gender
Offered Tested Offered %
Allmen
Men
(by sexual
orientation)
Total
New STI
episode2
Women
(including
women who
have sex with
women)
30. HIV in the UK – Situation Report 2015: Incidence, prevalence and prevention
30
Appendix 6: Number of contacts and HIV diagnoses made through partner notification at STI clinics by risk group:
England, 2013 and 2014
2013 2014 2013 2014 2013 2014 2013 2014
Male (total) 1,592 1,747 1,284 1,444 79 86 6.2 6.0
Heterosexual 540 571 460 493 15 27 3.3 5.5
Men who have sex with men 1,018 1,150 799 929 60 59 7.5 6.4
Female (total) 443 478 385 386 25 16 7 4.1
Heterosexual 421 466 365 375 23 15 6.3 4.0
Women who have sex with women 4 4 4 3 0 0 0.0 0.0
Ethnicity
White 1,355 1,493 1,130 1,264 69 63 6.1 5.0
Black or Black British 352 324 280 253 17 19 6 7.5
Asian or Asian British 85 98 71 82 4 3 5.6 3.7
Mixed 85 107 71 90 5 3 7.0 3.3
Other ethnic groups 52 50 37 37 3 3 8 8.1
Unknown 106 153 80 104 6 11 8 11
Total 2,035 2,225 1,669 1,830 104 102 6.2 5.6
Note: Appendices show actual numbers. Numbers presented in text are rounded.
Number of PN
contacts
Number of PN contacts
tested (a)
Number of PN
contacts diagnosed (b)
Percentage of PN
contacts diagnosed (b/a) %Gender & sexual orientation