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Challenges in frailty-related information use and
decision making in clinical practice
Sarah Damanti, MD
Geriatric Unit IRCCS Ca’ Granda Ospedale Maggiore Policlinico, Milano
University of Milan, PhD in Nutritional Sciences
INFORMATICS FOR HEALTH 2017
HEALTHCARE INFORMATION STANDARDS FOR FRAILTY: WHY, WHEN AND HOW
Frailty is a multidimensional dynamic condition,
whose prevalence increases with age, but is
independent of chronological age, characterized
by decreased physiological resilience and a
weakened response to stressors.
The Journals of Gerontology Series A: Biological Sciences and Medical Sciences, 2013. 68(1): p. 62-67
Romero-Ortuno, R. and R.A. Kenny, The frailty index in Europeans: association with age and mortality. Age and Ageing,
2012
Three months ago, Mr. Smith
underwent surgical removal of a
prostatic adenoma. After surgery he
developed an urinary tract infection
from a very aggressive bacterium so he
remained hospitalized for 2 weeks .
STRESSORS
Since the discharge something changed
 He lost weight (5 Kg ) without
particular reasons or symptoms.
 He keeps feeling tired and refuses to
leave his house and to perform some
of the everyday activities he used to.
REDUCED
RESILIENCE
Is it important to screen for frailty?
Frail individuals, having a weakened response to
stressors, are predisposed to poor clinical
outcomes (disability, dementia and falls) and
adverse events (hospitalization, institutionalization
and mortality).
The Lancet, 2013. 381(9868): p. 752-762.
Hazzard, W.R., et al., eds. Frailty: in Principles of Geriatric Medicine and Gerontology. 1999, McGraw Hill New York 1119-1156
 Moreover, he has fallen several times without
an apparent cause.
 The frequency of these falls has increased in the
las two weeks
POOR CLINICAL OUTCOMES
However, being frailty a potentially reversible
condition it is challenging but possible to reverse it,
also to reduce the health care expenditure.
How to deal with frailty complexity?
GEM
Geriatric Evaluation and
Management
 Appropriate Prescribing
 Behavioral Disturbances in Dementia
 Delirium
 Dementia
 Depression
 Diabetes Mellitus
 Falls
 Frailty
 Insomnia
 Lower Urinary Tract Symptoms in Men
 Multimorbidity
 Nutrition and Weight
 Osteoporosis
 PainPalliative Symptom Management
 Pressure UlcersPreventionPrognosticationSyncope
 Urinary Incontinence
MULTIDIMENSIONAL BUT…..
…..OFTEN TOO LONG!!!!
 Longer to triage
 Spend more time in the ED
 Consume more resources (laboratory studies, X ray )
 Missed or incorrect diagnosis are frequent
 Are more frequently admitted
 Undergo adverse health oucomes after the
discharge
 Lack of information OR excess of information
 Atypical presentations
 Altered laboratory values
 Comorbidity
 Polypharmacy
 Communication problems (aphasia, deafness)
 Altered mental status (delirium, dementia)
On arriving to the Emergency Department,
Mr. Smith his very confused and agitated.
His blood pressure is elevated.
Since he kept being agitated and tried to get
off the stretcher, he was given a sedative
POOR CLINICAL OUTCOME: DELIRIUM
It was very difficult for the ED physician to
get information he needed because Mr.
Smith was unable to refer his medical
history and kept complaining of the pain in
his leg, while his wife was really
frightened.
She has forgotten tablet boxes at home
and she could not remember the therapy
of his husband .
DIFFICULTIES IN GETTING
INFORMATION
OBSERVATIONS UNITS
What is the role of informatic devices in ED
setting?
HOSPITALIZATION
Which problems we have in managing
hospitalized frail people?
During his initial evaluation, the admitting
physician asked Mr. Smith about which
medications he was taking, but the
patient could not recall what they were
or the doses
HOW TO GET THE PROPER
INFORMATION IN AN
EASIER WAY?
The physician on the hospital team
contacted Dr. Care, who provided a
medical history and general list of
medications. The GP provided the
hospital team with contact information
for urologist as well
POLIPHARMACY
How to deal with polipharmacy?
 A structured, critical examination of a patient’s medicines
 Optimizing the impact of medicines
 Minimizing the number of medication related problems
 Reducing waste
MEDICATION REVIEW
 the medication prescribed is appropriate for the patient’s needs
 the medication is effective for the patient
 the medication is a cost effective choice
 any required monitoring has been done or arrangements are in
place
Check that:
Consider:
 drug interactions
 side effects
 compliance
 complementary medicines
 lifestyle and non-medicinal interventions
 unmet need
What is the role of informatic devices in
dealing with polipharmacy?
Drugs Aging. 2013 Oct;30(10):821-8.
Prevention of inappropriate prescribing in hospitalized
older patients using a computerized prescription
support system (INTERcheck(®)).
The use of INTERCheck(®) was associated with a significant reduction in potentially
inappropriate medications and new-onset potentially severe DDIs. CPSSs combining
different prescribing quality measures should be considered as an important strategy for
optimizing medication prescription for elderly patients.
Polypharmacy is very common among older adults and can lead to inappropriate prescribing,
poor adherence to treatment, adverse drug events and the prevalence of potential drug-drug
interactions (DDIs). Electronic prescription database software may help to prevent
inappropriate prescribing and minimize the occurrence of adverse drug reactions.
INTERcheck(®) is a Computerized Prescription Support System (CPSS) developed in order to
optimize drug prescription for elderly people with multimorbidity.
REHAB
Lost of many of his previous
abilities
Not able anymore to walk without
cane and only for short sections.
Mrs. Smith is very worried about
the home reentry.
She talks with the social assistant
and the geriatrician.
Both recommend her to activate
home services and adapt the
ground floor in the bathroom.
RESIDENTIAL HOME
Before going home, the nurse reviewed important
information with him and his wife, who was taking him
home.
Few new prescriptions
Necessity to continue rehabilitation at home with a
physiotherapist
Mrs. Smith should schedule a follow-up appointment with
his primary care physician within 3 days
Mr. Smith was prescribed wheelchair for displacements
out of his house
Renovations have been performed and home services made
available (support in household tasks for two hours three
days a week).
CONTINUTY OF CARE
REDUCED LEVEL OF
AUTONOMY
Int J Integr Care. 2014 Apr-Jun
Cochrane Database Syst Rev. 2010 Jan 20;(1):CD000313.
Discharge planning from hospital to home.
The evidence suggests that a structured discharge plan tailored to the
individual patient probably brings about small reductions in hospital length of stay and
readmission rates for older people admitted to hospital with a medical condition.
What is the role of informatic devices in
hospital discharge?
MoveCare: Multiple-actOrs Virtual Empathic CARgiver for the Elder
MOVECARE aims at supporting the
independent living of the elders at
home; monitoring their daily
activities while promoting their
cognitive, physical, and social
activities.
Project ID 732158
http:www.movecare-project.eu
A mobile robot with the needed abilities to assist
elder people at home.
Fully integrated within the MOVECARE ecosystem to
serve as an autonomous assistant for the elder at
home
The Giraff robotic platform
Thank
you for
the
attention

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Healthcare Information Standards for Frailty: Why, When and How (3 of 5)

  • 1. Challenges in frailty-related information use and decision making in clinical practice Sarah Damanti, MD Geriatric Unit IRCCS Ca’ Granda Ospedale Maggiore Policlinico, Milano University of Milan, PhD in Nutritional Sciences INFORMATICS FOR HEALTH 2017 HEALTHCARE INFORMATION STANDARDS FOR FRAILTY: WHY, WHEN AND HOW
  • 2. Frailty is a multidimensional dynamic condition, whose prevalence increases with age, but is independent of chronological age, characterized by decreased physiological resilience and a weakened response to stressors. The Journals of Gerontology Series A: Biological Sciences and Medical Sciences, 2013. 68(1): p. 62-67 Romero-Ortuno, R. and R.A. Kenny, The frailty index in Europeans: association with age and mortality. Age and Ageing, 2012
  • 3. Three months ago, Mr. Smith underwent surgical removal of a prostatic adenoma. After surgery he developed an urinary tract infection from a very aggressive bacterium so he remained hospitalized for 2 weeks . STRESSORS Since the discharge something changed  He lost weight (5 Kg ) without particular reasons or symptoms.  He keeps feeling tired and refuses to leave his house and to perform some of the everyday activities he used to. REDUCED RESILIENCE
  • 4.
  • 5. Is it important to screen for frailty?
  • 6. Frail individuals, having a weakened response to stressors, are predisposed to poor clinical outcomes (disability, dementia and falls) and adverse events (hospitalization, institutionalization and mortality). The Lancet, 2013. 381(9868): p. 752-762. Hazzard, W.R., et al., eds. Frailty: in Principles of Geriatric Medicine and Gerontology. 1999, McGraw Hill New York 1119-1156
  • 7.  Moreover, he has fallen several times without an apparent cause.  The frequency of these falls has increased in the las two weeks POOR CLINICAL OUTCOMES
  • 8. However, being frailty a potentially reversible condition it is challenging but possible to reverse it, also to reduce the health care expenditure.
  • 9. How to deal with frailty complexity?
  • 11.  Appropriate Prescribing  Behavioral Disturbances in Dementia  Delirium  Dementia  Depression  Diabetes Mellitus  Falls  Frailty  Insomnia  Lower Urinary Tract Symptoms in Men  Multimorbidity  Nutrition and Weight  Osteoporosis  PainPalliative Symptom Management  Pressure UlcersPreventionPrognosticationSyncope  Urinary Incontinence MULTIDIMENSIONAL BUT….. …..OFTEN TOO LONG!!!!
  • 12.
  • 13.  Longer to triage  Spend more time in the ED  Consume more resources (laboratory studies, X ray )  Missed or incorrect diagnosis are frequent  Are more frequently admitted  Undergo adverse health oucomes after the discharge  Lack of information OR excess of information  Atypical presentations  Altered laboratory values  Comorbidity  Polypharmacy  Communication problems (aphasia, deafness)  Altered mental status (delirium, dementia)
  • 14. On arriving to the Emergency Department, Mr. Smith his very confused and agitated. His blood pressure is elevated. Since he kept being agitated and tried to get off the stretcher, he was given a sedative POOR CLINICAL OUTCOME: DELIRIUM It was very difficult for the ED physician to get information he needed because Mr. Smith was unable to refer his medical history and kept complaining of the pain in his leg, while his wife was really frightened. She has forgotten tablet boxes at home and she could not remember the therapy of his husband . DIFFICULTIES IN GETTING INFORMATION
  • 15.
  • 16.
  • 18. What is the role of informatic devices in ED setting?
  • 19.
  • 20. HOSPITALIZATION Which problems we have in managing hospitalized frail people?
  • 21. During his initial evaluation, the admitting physician asked Mr. Smith about which medications he was taking, but the patient could not recall what they were or the doses HOW TO GET THE PROPER INFORMATION IN AN EASIER WAY? The physician on the hospital team contacted Dr. Care, who provided a medical history and general list of medications. The GP provided the hospital team with contact information for urologist as well
  • 22.
  • 23.
  • 25.
  • 26. How to deal with polipharmacy?
  • 27.  A structured, critical examination of a patient’s medicines  Optimizing the impact of medicines  Minimizing the number of medication related problems  Reducing waste MEDICATION REVIEW
  • 28.  the medication prescribed is appropriate for the patient’s needs  the medication is effective for the patient  the medication is a cost effective choice  any required monitoring has been done or arrangements are in place Check that: Consider:  drug interactions  side effects  compliance  complementary medicines  lifestyle and non-medicinal interventions  unmet need
  • 29. What is the role of informatic devices in dealing with polipharmacy?
  • 30.
  • 31. Drugs Aging. 2013 Oct;30(10):821-8. Prevention of inappropriate prescribing in hospitalized older patients using a computerized prescription support system (INTERcheck(®)). The use of INTERCheck(®) was associated with a significant reduction in potentially inappropriate medications and new-onset potentially severe DDIs. CPSSs combining different prescribing quality measures should be considered as an important strategy for optimizing medication prescription for elderly patients. Polypharmacy is very common among older adults and can lead to inappropriate prescribing, poor adherence to treatment, adverse drug events and the prevalence of potential drug-drug interactions (DDIs). Electronic prescription database software may help to prevent inappropriate prescribing and minimize the occurrence of adverse drug reactions. INTERcheck(®) is a Computerized Prescription Support System (CPSS) developed in order to optimize drug prescription for elderly people with multimorbidity.
  • 32.
  • 33.
  • 34. REHAB Lost of many of his previous abilities Not able anymore to walk without cane and only for short sections. Mrs. Smith is very worried about the home reentry. She talks with the social assistant and the geriatrician. Both recommend her to activate home services and adapt the ground floor in the bathroom. RESIDENTIAL HOME
  • 35. Before going home, the nurse reviewed important information with him and his wife, who was taking him home. Few new prescriptions Necessity to continue rehabilitation at home with a physiotherapist Mrs. Smith should schedule a follow-up appointment with his primary care physician within 3 days Mr. Smith was prescribed wheelchair for displacements out of his house Renovations have been performed and home services made available (support in household tasks for two hours three days a week). CONTINUTY OF CARE REDUCED LEVEL OF AUTONOMY
  • 36.
  • 37. Int J Integr Care. 2014 Apr-Jun
  • 38. Cochrane Database Syst Rev. 2010 Jan 20;(1):CD000313. Discharge planning from hospital to home. The evidence suggests that a structured discharge plan tailored to the individual patient probably brings about small reductions in hospital length of stay and readmission rates for older people admitted to hospital with a medical condition.
  • 39. What is the role of informatic devices in hospital discharge?
  • 40. MoveCare: Multiple-actOrs Virtual Empathic CARgiver for the Elder MOVECARE aims at supporting the independent living of the elders at home; monitoring their daily activities while promoting their cognitive, physical, and social activities. Project ID 732158 http:www.movecare-project.eu
  • 41. A mobile robot with the needed abilities to assist elder people at home. Fully integrated within the MOVECARE ecosystem to serve as an autonomous assistant for the elder at home The Giraff robotic platform
  • 42.

Editor's Notes

  1. The clinical approach towards acutely ill elder patients presenting to the ED can be highly complicated, especially when physicians are not familiar with their management . Atypical presentations, altered laboratory values, comorbidity, polypharmacy, communication problems (aphasia, deafness) and altered mental status (delirium, dementia) are frequent and complicate the collection of anamnesis. The presence of a relative, cohabitant or caregiver, who might compensate for communication or cognitive defects, is often indispensable. On the contrary, sometimes an excess of information (enormous amount of charts, reports and other documentation, often useless) creates embarrassment. The survey and appraisal of objective data (physical examination) could be very difficult too, and should take into account the whole clinical picture (e.g., non-verbal communication of pain in a demented elderly patient). Atypical presentation of medical conditions is frequent in elderly patients, as these presentations are not only limited to variability in clinical signs and symptoms but also involve psycho-cognitive and functional domains. Any type of acute illness can underlie loss of autonomy, immobilisation, falls, incontinence, reduced cognitive performance and delirium, but the main issue is that non-recognition of an atypical feature is not without consequences