Growth hormone deficiency (GHD), also known as dwarfism or pituitary dwarfism, is a condition caused by insufficient amounts of growth hormone in the body. Children with GHD have abnormally short stature with normal body proportions. GHD can be present at birth (congenital) or develop later (acquired).
In this mini-review benefits and risks of Growth Hormone (GH) replacement therapy in adults with GH deficiency are discussed. In addition, a cost-benefit analysis will be made and the inevitable illicit use and doping of growth hormone will be considered. Global human growth hormone market is expected to rise to USD 7,1 billion in 2025 and is the fastest growing market segment in Pharma due to extending GH treatment indications and investments of large players. Growth hormone use in anti-aging is highly controversial but booming. New guidelines are discussed as well as the recently FDA approved ghrelin oral GH stimulation test. The very recent horizon view of the Growth Hormone Research Society is discussed as well as the proteomic search for putative new biomarkers for detecting GH defiency in patients and doping in athletes. GH replacement therapy in children remains a costly treatment with USD 35.000-50.000 for each gained inch in height.
Physical Activity during Pregnancy and the Effect on Mothers and Fet.docxmattjtoni51554
Physical Activity during Pregnancy and the Effect on Mothers and Fetal Health
Abstract
1.2 Introduction:
Physical activity is an essential role that all people should engaged, aerobic and muscle strength exercises are an easy to do where the benefits of it are great, prevention, treatment of disease and keeping fit in all stage of life even in pregnancy period and this exercises can be modify to suit physical condition of the pregnant womens
Pregnancy is a blessing from Allah that every woman wishes. Pregnancy it’s condition that many changes it happened on women bodies from the day of fertilization to the day after delivery of the baby and the popular effect in women bodies it’s the increment of body weight, as it's known that many women they didn’t control them weight and they become overweight or obese, in this condition the pregnant woman she will be in danger, many diseases start with increase of the body weight and it may lead to a serious health problems. Without controlling the body weight increment, woman with a normal weight it may become an overweight or even obese.
In general overweight and obesity one of prevalence public issue that affect many countries in the world where it’s observe in all ages, adults, adolescents, and children it maybe became a global epidemic , the impact of this issue has a strong relationship with mortality and morbidity also this relationship have been known for more than 2000 between health professionals[1-2]. body mass index (BMI) is the way that give a right measurement for the total body fat compare with body weight, the method for calculation by determining the body weight in kilogram and divide it by height in meter squared, this way determine the degree of overweight easy with a reliable number.
There are interventions that can control the body weight before pregnancy period, during pregnancy period and after it, but the most important intervention that we will cover it’s the physical activity or exercise and the advantages for this intervention on the mother health and the outcome also the disadvantages that it can happen if available.
Physical activity and exercise has a great impact on health status, where there are many study done to prove this relation. where health outcome in people with physical inactivity is a major problem in the world and specially in developed countries. In worldwide physical inactivity appear in a huge number where one out of every five adults is physically inactive and the long period of sitting independent show that is a risk factor for mortality[3]
The healthy body weight in pregnancy it depends on the body mass index (BMI) so the WHO classify the BMI into four categories underweight: <18.5 kg/m2, normal weight: 18.5-24.99 kg/m2, overweight: 25-29.9 kg/m2, and obese ≥30 kg/m2 [4-5]. With this category, recognizing every case will be easy and right grouping will be more accurate.
all pregnant women are included in all age and different country.
In this mini-review benefits and risks of Growth Hormone (GH) replacement therapy in adults with GH deficiency are discussed. In addition, a cost-benefit analysis will be made and the inevitable illicit use and doping of growth hormone will be considered. Global human growth hormone market is expected to rise to USD 7,1 billion in 2025 and is the fastest growing market segment in Pharma due to extending GH treatment indications and investments of large players. Growth hormone use in anti-aging is highly controversial but booming. New guidelines are discussed as well as the recently FDA approved ghrelin oral GH stimulation test. The very recent horizon view of the Growth Hormone Research Society is discussed as well as the proteomic search for putative new biomarkers for detecting GH defiency in patients and doping in athletes. GH replacement therapy in children remains a costly treatment with USD 35.000-50.000 for each gained inch in height.
Physical Activity during Pregnancy and the Effect on Mothers and Fet.docxmattjtoni51554
Physical Activity during Pregnancy and the Effect on Mothers and Fetal Health
Abstract
1.2 Introduction:
Physical activity is an essential role that all people should engaged, aerobic and muscle strength exercises are an easy to do where the benefits of it are great, prevention, treatment of disease and keeping fit in all stage of life even in pregnancy period and this exercises can be modify to suit physical condition of the pregnant womens
Pregnancy is a blessing from Allah that every woman wishes. Pregnancy it’s condition that many changes it happened on women bodies from the day of fertilization to the day after delivery of the baby and the popular effect in women bodies it’s the increment of body weight, as it's known that many women they didn’t control them weight and they become overweight or obese, in this condition the pregnant woman she will be in danger, many diseases start with increase of the body weight and it may lead to a serious health problems. Without controlling the body weight increment, woman with a normal weight it may become an overweight or even obese.
In general overweight and obesity one of prevalence public issue that affect many countries in the world where it’s observe in all ages, adults, adolescents, and children it maybe became a global epidemic , the impact of this issue has a strong relationship with mortality and morbidity also this relationship have been known for more than 2000 between health professionals[1-2]. body mass index (BMI) is the way that give a right measurement for the total body fat compare with body weight, the method for calculation by determining the body weight in kilogram and divide it by height in meter squared, this way determine the degree of overweight easy with a reliable number.
There are interventions that can control the body weight before pregnancy period, during pregnancy period and after it, but the most important intervention that we will cover it’s the physical activity or exercise and the advantages for this intervention on the mother health and the outcome also the disadvantages that it can happen if available.
Physical activity and exercise has a great impact on health status, where there are many study done to prove this relation. where health outcome in people with physical inactivity is a major problem in the world and specially in developed countries. In worldwide physical inactivity appear in a huge number where one out of every five adults is physically inactive and the long period of sitting independent show that is a risk factor for mortality[3]
The healthy body weight in pregnancy it depends on the body mass index (BMI) so the WHO classify the BMI into four categories underweight: <18.5 kg/m2, normal weight: 18.5-24.99 kg/m2, overweight: 25-29.9 kg/m2, and obese ≥30 kg/m2 [4-5]. With this category, recognizing every case will be easy and right grouping will be more accurate.
all pregnant women are included in all age and different country.
Hypoglycaemia and improved testicular parameters in Sesamum radiatum treated ...lukeman Joseph Ade shittu
The development of a new dietary adjunct with a novel natural antioxidant impact on diabetes mellitus with prevention of its long term deleterious effect on the male fertility in general has been increasingly expressed in recent time. Hence, we aim to evaluate the effects of aqueous extract of Sesame radiatum leaves on adult male Sprague Dawley rats’ testis using unbiased stereological, biochemical and hormonal studies. Thirty adult male rats were divided into three groups of 10 rats each. The treated groups; 1 and 2 received 28.0 and 14 mg/kg bwt of aqueous extract of sesame leaves via oral garvage, respectively, while the control group received equal volume of 0.9% (w/v) normal saline per day for 6 weeks. Serum follicle-stimulating hormone (FSH), testosterone and blood glucose were assayed. In addition five microns of uniformly random transverse sections of processed testicular tissues were equally analyzed using an un-biased stereological study. The result showed that the mean percentage volume fractions (Vf) of epithelial cells and lumen of the testis were 76% (P<0.05)><0.05),>0.05) higher than the control in a dose related manner. Serum testosterone and FSH were significantly higher and lower, respectively, in the high dose sesame when compared to control. Sesame leaves intake improved glucose profile and testicular parameters in a dose related manner via possible improved insulin activity on the cells with a stimulatory impact on sperm production. This also confirmed its folkloric claims.
hCG is a hormone of great importance in maintenance and establishment of human pregnancy. It is composed of 2 subunits and exists in four forms. It is mainly secreted from syncytiotrophoblast and also from the pituitary gland. It play a very crucial role in maintaining the pregnancy, promote angiogenesis and placental growth as well. If some sort of disturbances occur in the level of hCG it promote a lot of problem like preeclampsia, miscarriages and fetal growth retardation etc.
Maybe it's the name human growth hormone that creates the misunderstanding. Many believe that HGH is not needed once you stop growing. Researchers tell us it is a different story.
Company Chosen Suncorp Bank Across Australia and globally, th.docxjanthony65
Company Chosen: Suncorp Bank
Across Australia and globally, the nature and practice of Human Resource Management (HRM) is in a constant state of evolution as organisational forms, management standards, labour markets and whole economies shift, adapt and change. In this assignment you are required to select an organisation, and undertake an investigation and evaluation regarding the HRM practices and policies present in that organisation. Your assignment is thus in two parts. The first section (of approximately 900 words) requires you to account for, and discuss, the ways in which your selected organisation:
· Recruits and inducts new staff
· Manages staff performance and engagement
· Identifies and advances high performing staff
· Ensures that staff operate safely
· Advances a diversity agenda across its staff and management base
· Encourages staff to stay at the organisation
· Resolves disputes and/or negotiates pay and benefits
In the second part of the assignment (approximately 1100 words in length) you should offer informed suggestions, supported by peer-reviewed academic literature (i.e. quality journal articles) on how the organisation can better structure its HRM practices and policies to advance employee performance (such as engagement, wellbeing, safety, commitment etc.) and organisational outcomes (e.g. profit and standing). Your suggestions should be critical and based on evidence, and at least 8 peer-reviewed academic articles should be cited in this section.
Home-based exergaming among children with
overweight and obesity: a randomized clinical trial
A. E. Staiano , R. A. Beyl , W. Guan , C. A. Hendrick , D. S. Hsia and
R. L. Newton Jr.
Pennington Biomedical Research Center, Baton
Rouge, Louisiana, USA
Address for correspondence:
AE Staiano, Pennington Biomedical
Research Center, 6400 Perkins Rd,
Baton Rouge, LA 70815, USA.
E-mail: [email protected]
Received 14 February 2018; revised 30 April 2018;
accepted 26 May 2018
Summary
Background: Given children’s low levels of physical activity and high
prevalence of obesity, there is an urgent need to identify innovative physical activity
options.
Objective: This study aims to test the effectiveness of exergaming (video
gaming that involves physical activity) to reduce children’s adiposity and improve
cardiometabolic health.
Methods: This randomized controlled trial assigned 46 children with
overweight/obesity to a 24-week exergaming or control condition. Intervention par-
ticipants were provided a gaming console with exergames, a gameplay curriculum
(1 h per session, three times a week) and video chat sessions with a fitness coach
(telehealth coaching). Control participants were provided the exergames following fi-
nal clinic visit. The primary outcome was body mass index (BMI) z-score. Secondary
outcomes were fat mass by dual energy X-ray absorptiometry and cardiometabolic
health metrics.
Results: Half of the participants were girls, and 57% were African–American.
Int.
Company Chosen Suncorp Bank Across Australia and globally, th.docxtemplestewart19
Company Chosen: Suncorp Bank
Across Australia and globally, the nature and practice of Human Resource Management (HRM) is in a constant state of evolution as organisational forms, management standards, labour markets and whole economies shift, adapt and change. In this assignment you are required to select an organisation, and undertake an investigation and evaluation regarding the HRM practices and policies present in that organisation. Your assignment is thus in two parts. The first section (of approximately 900 words) requires you to account for, and discuss, the ways in which your selected organisation:
· Recruits and inducts new staff
· Manages staff performance and engagement
· Identifies and advances high performing staff
· Ensures that staff operate safely
· Advances a diversity agenda across its staff and management base
· Encourages staff to stay at the organisation
· Resolves disputes and/or negotiates pay and benefits
In the second part of the assignment (approximately 1100 words in length) you should offer informed suggestions, supported by peer-reviewed academic literature (i.e. quality journal articles) on how the organisation can better structure its HRM practices and policies to advance employee performance (such as engagement, wellbeing, safety, commitment etc.) and organisational outcomes (e.g. profit and standing). Your suggestions should be critical and based on evidence, and at least 8 peer-reviewed academic articles should be cited in this section.
Home-based exergaming among children with
overweight and obesity: a randomized clinical trial
A. E. Staiano , R. A. Beyl , W. Guan , C. A. Hendrick , D. S. Hsia and
R. L. Newton Jr.
Pennington Biomedical Research Center, Baton
Rouge, Louisiana, USA
Address for correspondence:
AE Staiano, Pennington Biomedical
Research Center, 6400 Perkins Rd,
Baton Rouge, LA 70815, USA.
E-mail: [email protected]
Received 14 February 2018; revised 30 April 2018;
accepted 26 May 2018
Summary
Background: Given children’s low levels of physical activity and high
prevalence of obesity, there is an urgent need to identify innovative physical activity
options.
Objective: This study aims to test the effectiveness of exergaming (video
gaming that involves physical activity) to reduce children’s adiposity and improve
cardiometabolic health.
Methods: This randomized controlled trial assigned 46 children with
overweight/obesity to a 24-week exergaming or control condition. Intervention par-
ticipants were provided a gaming console with exergames, a gameplay curriculum
(1 h per session, three times a week) and video chat sessions with a fitness coach
(telehealth coaching). Control participants were provided the exergames following fi-
nal clinic visit. The primary outcome was body mass index (BMI) z-score. Secondary
outcomes were fat mass by dual energy X-ray absorptiometry and cardiometabolic
health metrics.
Results: Half of the participants were girls, and 57% were African–American.
Int.
Company Chosen Suncorp Bank Across Australia and globally, th.docxmccormicknadine86
Company Chosen: Suncorp Bank
Across Australia and globally, the nature and practice of Human Resource Management (HRM) is in a constant state of evolution as organisational forms, management standards, labour markets and whole economies shift, adapt and change. In this assignment you are required to select an organisation, and undertake an investigation and evaluation regarding the HRM practices and policies present in that organisation. Your assignment is thus in two parts. The first section (of approximately 900 words) requires you to account for, and discuss, the ways in which your selected organisation:
· Recruits and inducts new staff
· Manages staff performance and engagement
· Identifies and advances high performing staff
· Ensures that staff operate safely
· Advances a diversity agenda across its staff and management base
· Encourages staff to stay at the organisation
· Resolves disputes and/or negotiates pay and benefits
In the second part of the assignment (approximately 1100 words in length) you should offer informed suggestions, supported by peer-reviewed academic literature (i.e. quality journal articles) on how the organisation can better structure its HRM practices and policies to advance employee performance (such as engagement, wellbeing, safety, commitment etc.) and organisational outcomes (e.g. profit and standing). Your suggestions should be critical and based on evidence, and at least 8 peer-reviewed academic articles should be cited in this section.
Home-based exergaming among children with
overweight and obesity: a randomized clinical trial
A. E. Staiano , R. A. Beyl , W. Guan , C. A. Hendrick , D. S. Hsia and
R. L. Newton Jr.
Pennington Biomedical Research Center, Baton
Rouge, Louisiana, USA
Address for correspondence:
AE Staiano, Pennington Biomedical
Research Center, 6400 Perkins Rd,
Baton Rouge, LA 70815, USA.
E-mail: [email protected]
Received 14 February 2018; revised 30 April 2018;
accepted 26 May 2018
Summary
Background: Given children’s low levels of physical activity and high
prevalence of obesity, there is an urgent need to identify innovative physical activity
options.
Objective: This study aims to test the effectiveness of exergaming (video
gaming that involves physical activity) to reduce children’s adiposity and improve
cardiometabolic health.
Methods: This randomized controlled trial assigned 46 children with
overweight/obesity to a 24-week exergaming or control condition. Intervention par-
ticipants were provided a gaming console with exergames, a gameplay curriculum
(1 h per session, three times a week) and video chat sessions with a fitness coach
(telehealth coaching). Control participants were provided the exergames following fi-
nal clinic visit. The primary outcome was body mass index (BMI) z-score. Secondary
outcomes were fat mass by dual energy X-ray absorptiometry and cardiometabolic
health metrics.
Results: Half of the participants were girls, and 57% were African–American.
Int ...
Four year follow-up of a randomized controlled trial of choline for neurodeve...BARRY STANLEY 2 fasd
Abstract
Background
Despite the high prevalence of fetal alcohol spectrum disorder (FASD), there are few interventions targeting its core neurocognitive and behavioral deficits. FASD is often conceptualized as static and permanent, but interventions that capitalize on brain plasticity and critical developmental windows are emerging. We present a long-term follow-up study evaluating the neurodevelopmental effects of choline supplementation in children with FASD 4 years after an initial efficacy trial
Mobile Decision Support System to Determine Toddler's Nutrition using Fuzzy S...IJECEIAES
Determination of nutritional status is closely related to the determination of dietary patterns should be given to infants. Nutrition is very important role in mental, physical development, and human productivity. In this study, the system based on android is developed to determine the nutritional status of infants by using Fuzzy Sugeno. Indicator variables are age, height, circle head, and body weight according to the male or female. In this study, the results of measurements of nutritional status of children with Fuzzy Sugenoare tested by comparing the nutritional quality of the data Posyandu toddler by using anthropometric tables. The results of the evaluation measurement accuracy in this application are compared with the results of manual calculation based infant growth charts according to WHO standards. Therefore, these applications can be used to help the community in monitoring the nutritional status of children so that the growth of children is more appropriate in line with expectations.
Presentation covers 3 topics: 1) Definition of infertility with brief review of female reproduction. 2) Discussion of how fertility status is evaluated with a description of some of the tests that are performed. 3) Review of several treatment options. By Dr. Arlene Morales of Fertility Specialists Medical Center (FSMG) http://ivfspecialists.com/
Progesterone Abnormalities up and down regulationArubSultan
Progesterone abnormalities refer to irregularities in the levels of the hormone progesterone, a crucial player in the female reproductive system. These imbalances can disrupt the menstrual cycle, leading to issues such as irregular periods, heavy bleeding, or amenorrhea. Inadequate progesterone levels may impact fertility, causing difficulty in conceiving or maintaining a pregnancy. Conversely, excess progesterone can result in symptoms like fatigue, mood swings, and breast tenderness. Progesterone abnormalities is essential for maintaining reproductive health and hormonal balance in both men and women. In men, imbalances in progesterone levels may impact libido, mood, and energy levels. Treatment for progesterone abnormalities typically involves hormone replacement therapy (HRT) to restore balance. In cases of low progesterone, supplemental progesterone medications, such as oral capsules or creams, may be prescribed. Lifestyle modifications, such as stress management and a healthy diet, can also positively impact progesterone levels.
DISCUS FISH Introduction Morphology and its behaviour characteristicsArubSultan
Discus fish (Kings of the Aquarium) are dazzling freshwater fish prized for their vibrant colors and round, flattened bodies. Native to the Amazon basin, these calm creatures are popular aquarium additions, but require specific care due to their sensitivity to water conditions .
R
Shark introduction Morphology and its behaviour characteristicsArubSultan
Sharks are a group of elasmobranch fish characterized by a cartilaginous skeleton, five to seven gill slits on the sides of the head, and pectoral fins that are not fused to the head. Modern sharks are classified within the clade Selachimorpha (or Selachii) and are the sister group to the Batoidea (rays and kin). Some sources extend the term "shark" as an informal category including extinct members of Chondrichthyes (cartilaginous fish) with a shark-like morphology, such as hybodonts. They generally do not live in freshwater, although there are a few known exceptions, such as the bull shark and the river shark, which can be found in both seawater and freshwater.Sharks have a covering of dermal denticles that protects their skin from damage and parasites in addition to improving their fluid dynamics. They have numerous sets of replaceable teeth.
More Related Content
Similar to Growth hormone abnormalities upregulation and downregulation of growth hormone
Hypoglycaemia and improved testicular parameters in Sesamum radiatum treated ...lukeman Joseph Ade shittu
The development of a new dietary adjunct with a novel natural antioxidant impact on diabetes mellitus with prevention of its long term deleterious effect on the male fertility in general has been increasingly expressed in recent time. Hence, we aim to evaluate the effects of aqueous extract of Sesame radiatum leaves on adult male Sprague Dawley rats’ testis using unbiased stereological, biochemical and hormonal studies. Thirty adult male rats were divided into three groups of 10 rats each. The treated groups; 1 and 2 received 28.0 and 14 mg/kg bwt of aqueous extract of sesame leaves via oral garvage, respectively, while the control group received equal volume of 0.9% (w/v) normal saline per day for 6 weeks. Serum follicle-stimulating hormone (FSH), testosterone and blood glucose were assayed. In addition five microns of uniformly random transverse sections of processed testicular tissues were equally analyzed using an un-biased stereological study. The result showed that the mean percentage volume fractions (Vf) of epithelial cells and lumen of the testis were 76% (P<0.05)><0.05),>0.05) higher than the control in a dose related manner. Serum testosterone and FSH were significantly higher and lower, respectively, in the high dose sesame when compared to control. Sesame leaves intake improved glucose profile and testicular parameters in a dose related manner via possible improved insulin activity on the cells with a stimulatory impact on sperm production. This also confirmed its folkloric claims.
hCG is a hormone of great importance in maintenance and establishment of human pregnancy. It is composed of 2 subunits and exists in four forms. It is mainly secreted from syncytiotrophoblast and also from the pituitary gland. It play a very crucial role in maintaining the pregnancy, promote angiogenesis and placental growth as well. If some sort of disturbances occur in the level of hCG it promote a lot of problem like preeclampsia, miscarriages and fetal growth retardation etc.
Maybe it's the name human growth hormone that creates the misunderstanding. Many believe that HGH is not needed once you stop growing. Researchers tell us it is a different story.
Company Chosen Suncorp Bank Across Australia and globally, th.docxjanthony65
Company Chosen: Suncorp Bank
Across Australia and globally, the nature and practice of Human Resource Management (HRM) is in a constant state of evolution as organisational forms, management standards, labour markets and whole economies shift, adapt and change. In this assignment you are required to select an organisation, and undertake an investigation and evaluation regarding the HRM practices and policies present in that organisation. Your assignment is thus in two parts. The first section (of approximately 900 words) requires you to account for, and discuss, the ways in which your selected organisation:
· Recruits and inducts new staff
· Manages staff performance and engagement
· Identifies and advances high performing staff
· Ensures that staff operate safely
· Advances a diversity agenda across its staff and management base
· Encourages staff to stay at the organisation
· Resolves disputes and/or negotiates pay and benefits
In the second part of the assignment (approximately 1100 words in length) you should offer informed suggestions, supported by peer-reviewed academic literature (i.e. quality journal articles) on how the organisation can better structure its HRM practices and policies to advance employee performance (such as engagement, wellbeing, safety, commitment etc.) and organisational outcomes (e.g. profit and standing). Your suggestions should be critical and based on evidence, and at least 8 peer-reviewed academic articles should be cited in this section.
Home-based exergaming among children with
overweight and obesity: a randomized clinical trial
A. E. Staiano , R. A. Beyl , W. Guan , C. A. Hendrick , D. S. Hsia and
R. L. Newton Jr.
Pennington Biomedical Research Center, Baton
Rouge, Louisiana, USA
Address for correspondence:
AE Staiano, Pennington Biomedical
Research Center, 6400 Perkins Rd,
Baton Rouge, LA 70815, USA.
E-mail: [email protected]
Received 14 February 2018; revised 30 April 2018;
accepted 26 May 2018
Summary
Background: Given children’s low levels of physical activity and high
prevalence of obesity, there is an urgent need to identify innovative physical activity
options.
Objective: This study aims to test the effectiveness of exergaming (video
gaming that involves physical activity) to reduce children’s adiposity and improve
cardiometabolic health.
Methods: This randomized controlled trial assigned 46 children with
overweight/obesity to a 24-week exergaming or control condition. Intervention par-
ticipants were provided a gaming console with exergames, a gameplay curriculum
(1 h per session, three times a week) and video chat sessions with a fitness coach
(telehealth coaching). Control participants were provided the exergames following fi-
nal clinic visit. The primary outcome was body mass index (BMI) z-score. Secondary
outcomes were fat mass by dual energy X-ray absorptiometry and cardiometabolic
health metrics.
Results: Half of the participants were girls, and 57% were African–American.
Int.
Company Chosen Suncorp Bank Across Australia and globally, th.docxtemplestewart19
Company Chosen: Suncorp Bank
Across Australia and globally, the nature and practice of Human Resource Management (HRM) is in a constant state of evolution as organisational forms, management standards, labour markets and whole economies shift, adapt and change. In this assignment you are required to select an organisation, and undertake an investigation and evaluation regarding the HRM practices and policies present in that organisation. Your assignment is thus in two parts. The first section (of approximately 900 words) requires you to account for, and discuss, the ways in which your selected organisation:
· Recruits and inducts new staff
· Manages staff performance and engagement
· Identifies and advances high performing staff
· Ensures that staff operate safely
· Advances a diversity agenda across its staff and management base
· Encourages staff to stay at the organisation
· Resolves disputes and/or negotiates pay and benefits
In the second part of the assignment (approximately 1100 words in length) you should offer informed suggestions, supported by peer-reviewed academic literature (i.e. quality journal articles) on how the organisation can better structure its HRM practices and policies to advance employee performance (such as engagement, wellbeing, safety, commitment etc.) and organisational outcomes (e.g. profit and standing). Your suggestions should be critical and based on evidence, and at least 8 peer-reviewed academic articles should be cited in this section.
Home-based exergaming among children with
overweight and obesity: a randomized clinical trial
A. E. Staiano , R. A. Beyl , W. Guan , C. A. Hendrick , D. S. Hsia and
R. L. Newton Jr.
Pennington Biomedical Research Center, Baton
Rouge, Louisiana, USA
Address for correspondence:
AE Staiano, Pennington Biomedical
Research Center, 6400 Perkins Rd,
Baton Rouge, LA 70815, USA.
E-mail: [email protected]
Received 14 February 2018; revised 30 April 2018;
accepted 26 May 2018
Summary
Background: Given children’s low levels of physical activity and high
prevalence of obesity, there is an urgent need to identify innovative physical activity
options.
Objective: This study aims to test the effectiveness of exergaming (video
gaming that involves physical activity) to reduce children’s adiposity and improve
cardiometabolic health.
Methods: This randomized controlled trial assigned 46 children with
overweight/obesity to a 24-week exergaming or control condition. Intervention par-
ticipants were provided a gaming console with exergames, a gameplay curriculum
(1 h per session, three times a week) and video chat sessions with a fitness coach
(telehealth coaching). Control participants were provided the exergames following fi-
nal clinic visit. The primary outcome was body mass index (BMI) z-score. Secondary
outcomes were fat mass by dual energy X-ray absorptiometry and cardiometabolic
health metrics.
Results: Half of the participants were girls, and 57% were African–American.
Int.
Company Chosen Suncorp Bank Across Australia and globally, th.docxmccormicknadine86
Company Chosen: Suncorp Bank
Across Australia and globally, the nature and practice of Human Resource Management (HRM) is in a constant state of evolution as organisational forms, management standards, labour markets and whole economies shift, adapt and change. In this assignment you are required to select an organisation, and undertake an investigation and evaluation regarding the HRM practices and policies present in that organisation. Your assignment is thus in two parts. The first section (of approximately 900 words) requires you to account for, and discuss, the ways in which your selected organisation:
· Recruits and inducts new staff
· Manages staff performance and engagement
· Identifies and advances high performing staff
· Ensures that staff operate safely
· Advances a diversity agenda across its staff and management base
· Encourages staff to stay at the organisation
· Resolves disputes and/or negotiates pay and benefits
In the second part of the assignment (approximately 1100 words in length) you should offer informed suggestions, supported by peer-reviewed academic literature (i.e. quality journal articles) on how the organisation can better structure its HRM practices and policies to advance employee performance (such as engagement, wellbeing, safety, commitment etc.) and organisational outcomes (e.g. profit and standing). Your suggestions should be critical and based on evidence, and at least 8 peer-reviewed academic articles should be cited in this section.
Home-based exergaming among children with
overweight and obesity: a randomized clinical trial
A. E. Staiano , R. A. Beyl , W. Guan , C. A. Hendrick , D. S. Hsia and
R. L. Newton Jr.
Pennington Biomedical Research Center, Baton
Rouge, Louisiana, USA
Address for correspondence:
AE Staiano, Pennington Biomedical
Research Center, 6400 Perkins Rd,
Baton Rouge, LA 70815, USA.
E-mail: [email protected]
Received 14 February 2018; revised 30 April 2018;
accepted 26 May 2018
Summary
Background: Given children’s low levels of physical activity and high
prevalence of obesity, there is an urgent need to identify innovative physical activity
options.
Objective: This study aims to test the effectiveness of exergaming (video
gaming that involves physical activity) to reduce children’s adiposity and improve
cardiometabolic health.
Methods: This randomized controlled trial assigned 46 children with
overweight/obesity to a 24-week exergaming or control condition. Intervention par-
ticipants were provided a gaming console with exergames, a gameplay curriculum
(1 h per session, three times a week) and video chat sessions with a fitness coach
(telehealth coaching). Control participants were provided the exergames following fi-
nal clinic visit. The primary outcome was body mass index (BMI) z-score. Secondary
outcomes were fat mass by dual energy X-ray absorptiometry and cardiometabolic
health metrics.
Results: Half of the participants were girls, and 57% were African–American.
Int ...
Four year follow-up of a randomized controlled trial of choline for neurodeve...BARRY STANLEY 2 fasd
Abstract
Background
Despite the high prevalence of fetal alcohol spectrum disorder (FASD), there are few interventions targeting its core neurocognitive and behavioral deficits. FASD is often conceptualized as static and permanent, but interventions that capitalize on brain plasticity and critical developmental windows are emerging. We present a long-term follow-up study evaluating the neurodevelopmental effects of choline supplementation in children with FASD 4 years after an initial efficacy trial
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Growth hormone abnormalities upregulation and downregulation of growth hormone
1.
2. Presented by: Noor ul ain
Roll no: 20M-UOC/ZOL-04
BS: Zoology
Semester: 7th(Morning)
Course Title: Endocrinology
Presented to: Dr.Syeda Nadia
GROWTH HORMONE ABNORMALITIES
University of Chakwal
Department of Zoology
3. Introduction
- Growth hormone (GH), also called somatotropin or human growth
hormone
- It stimulates the growth of essentially all tissues of the body, including
bone
- GH is synthesized and secreted by anterior pituitary cells called
somatotrophs,
- GH is vital for normal physical growth in children;(Wu, W., & Chen, R.
2023)
5. Function
In biochemical terms, GH stimulates
protein synthesis and increases fat
breakdown to provide the energy
necessary for tissue growth.
It also antagonizes (opposes) the action
of insulin. ( Yuen K. C et al., 2019) Figure 1.2: Growth hormone
(https://images.app.goo.gl/391ZqpL17j7
Ynt8F8)
7. 1.Excess of Growth hormone
- (Excess of GH) in the body, a
condition known as acromegaly
- when it occurs in adults or gigantism
when it affects children and
adolescents (Cristin L et al., 2023)
Figure 1.3:Excess of Growth
hormone
(https://images.app.goo.gl/TeYCn7
WBijZK3x1RA)
8. Key aspects of Growth hormone Excess
- 1. Skeletal Changes:
- 2. Soft Tissue Growth
- 3. Joint and Muscle Problem
- 4. Metabolic Effects:
- 5. Cardiovascular Issues
- 6. Respiratory and Sleep Problems:
- 7. Vision Impairment:
- 8. Increased Cancer Risk:
- 9. Psychological and Emotional Impact
9. 2.Growth hormone deficiency
- Growth hormone deficiency (GHD) is a medical condition where
the body doesn’t produce enough growth hormone (GH).
- This condition can affect both children and adults and has various
effects on the body. (Boluses et al., 2023)
10. - In children
• StuntedGrowth
• Delayed Development
• Impaired muscle development
• Metaboliceffects
• Psychological and emotional impacts
Figure 1.4:Growth hormone deficiency in children (https://images.app.goo.gl/EeWXCQh4AB58XLwh6)
11. - In Adults
- Decrease Bone Density
- Decreased muscle mass
- Change in body composition
- Cardiovascular Effects
Figure 1.5: Growth hormone deficiency in adults
https://images.app.goo.gl/o532Z5vSEoK2G21YA
12. 3.Pituitary Tumors
Benign or malignant tumors in
the pituitary gland can disrupt the
regulation of growth hormone,
causing both excess and
deficiency(Dhaneshwar et al.,
2019)
Figure1.6: Pituitary Tumors
https://images.app.goo.gl/5i42V5
NiqhxaUmzc7
13. 4.Idiopathic short stature
- Some individuals are shorter than average without a known cause,
- This might be due to subtle growth hormone abnormalities
5.Turner Syndrome
- In females with Turner syndrome, there may be a deficiency in
growth hormone, leading to short stature.
Figure 1.7: Idiopathic short
stature
https://images.app.goo.gl/2N
KE5qvZ87Kea9U
14. Diagnosis
Diagnosis of GH abnormalities typically involves blood tests to measure GH
levels, imaging studies (like MRI or CT scans) to identify tumors or structural
issues, and other diagnostic procedures to determine the underlying cause. (Montini
et al., 2019)
Treatment
In Growth hormone Excess
• Management typicallyinvolves surgery to remove the tumor causing excess GH production(if present)
and may also includemedications to lower GH levels.
In Growth hormone deficiency
• The primary treatment for growth hormonedeficiency is GH replacement therapy, which involves
administering synthetic GH to supplement the body’s deficient levels.( B. M., Radovick et al., 2021)
16. Research and future directions
- Genetic Insights
- Early diagnosis and screening
- Long term outcomes
- Cancer risk assessment
- Biomarkers and Monitoring
- Neuroendocrinology
17. -References:
- Wu, W., & Chen, R. (2023). The effect of growth hormone treatment in children with novel BPTF gene variants:
A report of two cases and literature review. Molecular Genetics & Genomic Medicine, 11(1), e2066.
- Yuen, K. C., Biller, B. M., Radovick, S., Carmichael, J. D., Jasim, S., Pantalone, K. M., & Hoffman, A. R. (2019).
American Association of Clinical Endocrinologists and American College of Endocrinology guidelines for
management of growth hormone deficiency in adults and patients transitioning from pediatric to adult care.
Endocrine Practice, 25(11), 1191-1232.
- Cristin, L., Montini, A., Martinino, A., Scarano Pereira, J. P., Giovinazzo, F., & Agnes, S. (2023). The Role of
Growth Hormone and Insulin Growth Factor 1 in the Developmentof Non-Alcoholic Steato-Hepatitis: A
- Boluses, C. L., da Silva Boguszewski, M. C., & de Herder,W. W. (2023). The science behind the relations
among cancer, height, growth patterns, and growth hormone axis. Endocrine-Related Cancer, 30(4).
