2. Definition :-
Glycolysis is defined as the
sequence of reactions converting
glucose (or glycogen) to pyruvate
or lactate, with the production of
ATP.
3. Glycolysis is derived from the Greek
words (glycose-sweet or sugar; lysis-
dissolution). It is a universal pathway in
the living cells. This pathway is also
known as Embden-Meyerhof- Parnas
pathway (EMP pathway).
Glycolysis (anaerobic) may be
summarized by the net reaction-
Glucose + 2ADP +Pi — 2Lactate+2ATP.
6. REACTIONS OF GLYCOLYSIS:-
There are three distinct phases
A. Energy Investment Phase or
Preparatory Phase.
B. Splitting Phase.
C. Energy Generation Phase.
7. ENERGETICS OF GLYCOLYSIS
Enzyme (method of ATP synthesis) Number of ATP
synthesized
Hexokinase and Phosphofructokinase -2
Phosphoglycerate kinase & Pyruvate kinase 4
Glyceraldehyde 3-phosphate dehydrogenase
(2 NADH, ETC, oxidative phosphorylation)
6
Net ATP synthesis in glycolysis in aerobic
condition
8