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PATHWAY, ENERGETICS, AND
SIGNIFICANCE
MADE BY :-MR. SANDIP PAL
Definition :-
Glycolysis is defined as the
sequence of reactions converting
glucose (or glycogen) to pyruvate
or lactate, with the production of
ATP.
Glycolysis is derived from the Greek
words (glycose-sweet or sugar; lysis-
dissolution). It is a universal pathway in
the living cells. This pathway is also
known as Embden-Meyerhof- Parnas
pathway (EMP pathway).
 Glycolysis (anaerobic) may be
summarized by the net reaction-
Glucose + 2ADP +Pi — 2Lactate+2ATP.
MADE BY:- MR. SANDIP PAL.
GLYCOLYSIS
PATHWAY :-
REACTIONS OF GLYCOLYSIS:-
There are three distinct phases
A. Energy Investment Phase or
Preparatory Phase.
B. Splitting Phase.
C. Energy Generation Phase.
ENERGETICS OF GLYCOLYSIS
Enzyme (method of ATP synthesis) Number of ATP
synthesized
Hexokinase and Phosphofructokinase -2
Phosphoglycerate kinase & Pyruvate kinase 4
Glyceraldehyde 3-phosphate dehydrogenase
(2 NADH, ETC, oxidative phosphorylation)
6
Net ATP synthesis in glycolysis in aerobic
condition
8
THANK YOU
LIKE, SHARE AND COMMENT
MADE BY: MR. SANDIP PAL

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Glycolysis - Pathway, Energetics and Significance

  • 2. Definition :- Glycolysis is defined as the sequence of reactions converting glucose (or glycogen) to pyruvate or lactate, with the production of ATP.
  • 3. Glycolysis is derived from the Greek words (glycose-sweet or sugar; lysis- dissolution). It is a universal pathway in the living cells. This pathway is also known as Embden-Meyerhof- Parnas pathway (EMP pathway).  Glycolysis (anaerobic) may be summarized by the net reaction- Glucose + 2ADP +Pi — 2Lactate+2ATP.
  • 4. MADE BY:- MR. SANDIP PAL.
  • 6. REACTIONS OF GLYCOLYSIS:- There are three distinct phases A. Energy Investment Phase or Preparatory Phase. B. Splitting Phase. C. Energy Generation Phase.
  • 7. ENERGETICS OF GLYCOLYSIS Enzyme (method of ATP synthesis) Number of ATP synthesized Hexokinase and Phosphofructokinase -2 Phosphoglycerate kinase & Pyruvate kinase 4 Glyceraldehyde 3-phosphate dehydrogenase (2 NADH, ETC, oxidative phosphorylation) 6 Net ATP synthesis in glycolysis in aerobic condition 8
  • 8. THANK YOU LIKE, SHARE AND COMMENT MADE BY: MR. SANDIP PAL