Giles Yeo: Communicating Your Science: Lessons from the Front Line
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Giles Yeo is a geneticist who studies obesity. He discusses communicating science effectively to different audiences using various mediums. Some key points he makes include: explaining the why, how, and what of scientific work; tailoring messages based on audience and medium; and simplifying concepts without being wrong. Yeo provides an example experiment where he studied how depriving cells of amino acids reduces levels of the FTO protein, which is linked to obesity.
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Giles Yeo: Communicating Your Science: Lessons from the Front Line
- 1. Giles Yeo gshy2@cam.ac.uk @GilesYeo Communicating Your Science: Lessons from the Front Line
- 2. Who am I and what do I do? I am a geneticist that studies obesity
- 3. Getting lunch – it’s a jungle out there Primal directives of life: 1. Find and eat food 2. Avoid becoming food 3. Reproduce 4. Repeat
- 5. Scully, Nature, 508(7496):S50-1, 2014
- 6. Energy balance Energy Intake Energy Expenditure Food Intake Basal Metabolism Physical Activity Adaptive Thermogenesis
- 7. Twin studies Heritability of BODY WEIGHT = Heritability of HEIGHT
- 8. Locke et al, Nature 2015
- 9. Your genes are like a hand of poker You can’t do anything about the cards you have But you can choose how to play them
- 10. We become fat because we eat more than we burn, but why we eat more is complex Obese people find it hard to lose weight NOT because they are BAD, but because of their biology Trying to understand the genetics between obese and lean people is NOT giving obese folk an excuse My message
- 11. King Canute
- 14. Why? How? What? Why are you doing what you are doing? What is the question? How have you chosen to answer the question? What have you found out? What does this mean? Introduction Aims and objectives Approach Materials and methods Results Discussion The foundation of scientific communication
- 15. AA Deprivation and FTO Protein Levels eIF2a FTO H3 N46 -AA (Hrs) 0 2 4 8 HEK 293 -AA (Hrs) 0 2 4 8 MEFs (wt) -AA (Hrs) 0 2 4 8 16 24 +AA Mouse Human Why How What Genetic variation – FTO – Obesity; Fasting reduces FTO expression. Why? Nutrients? Glucose? Amino acids? Use 3 cell-lines; Amino acid starved; FTO measured by Western blot. Amino acid starvation reduces FTO protein levels in 3 different cell-lines. In order to determine… We used/did/performed/ measured… We found that… This means…..
- 16. is a completely scalable concept Why? How? What? Individual experiments Projects Programmes Careers
- 17. Audience Academic Specialist Academic Non-specialist Educated lay Students Young students General public Difficulty
- 18. Simplify ≠ Wrong The cab-driver/David Cameron test
- 19. AA Deprivation and FTO Protein Levels eIF2a FTO H3 N46 -AA (Hrs) 0 2 4 8 HEK 293 -AA (Hrs) 0 2 4 8 MEFs (wt) -AA (Hrs) 0 2 4 8 16 24 +AA Mouse Human Why How What Genetic variation – FTO – Obesity; Fasting reduces FTO expression. Why? Nutrients? Glucose? Amino acids? Use 3 cell-lines; Amino acid starved; FTO measured by Western blot. Amino acid starvation reduces FTO protein levels in 3 different cell-lines. Audience Academic Specialist Academic Non-specialist Educated lay Students Young students General public
- 25. et al Social media….a useful tool or a curse?