General physical examination involves assessing the patient's general appearance, vital signs, and examining the hands, scalp/face/neck, lymph nodes, and edema. Examining the hands focuses on signs like clubbing, cyanosis, and nail changes. Examination of the face evaluates features such as jaundice, pallor, and oral lesions. Neck examination includes assessing carotid pulses, jugular venous pressure, thyroid, and lymph nodes. Vital signs include pulse, blood pressure, respiratory rate, temperature, oxygen saturation, and blood glucose.