GeneMind Biosciences specializes in developing molecular diagnosis technology through independent research and development of DNA sequencing systems. The company aims to build a precision medicine ecosystem through collaboration. GeneMind has launched two sequencing platforms, GenoCare 1600 for single molecule sequencing and GenoLab M for high throughput sequencing, offering a total solution. GeneMind is one of few companies worldwide with independent sequencing brands and core upstream technologies.
Ion torrent semiconductor sequencing technologyCD Genomics
Ion Torrent is the latest generation sequencing technology. Its core technology is the use of semiconductor technology in chemical and digital information to establish a direct link.
DNA repair, DNA Mutation, Gene Expression by Dr. Anurag YadavDr Anurag Yadav
Various causes of DNA damage,
Methods of DNA repair for the Damage to the DNA structure,
Gene regulation and Gene Expression in eukaryotes and Prokaryotes.
Để xem full tài liệu Xin vui long liên hệ page để được hỗ trợ
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tai lieu tong hop, thu vien luan van, luan van tong hop, do an chuyen nganh
Ion torrent semiconductor sequencing technologyCD Genomics
Ion Torrent is the latest generation sequencing technology. Its core technology is the use of semiconductor technology in chemical and digital information to establish a direct link.
DNA repair, DNA Mutation, Gene Expression by Dr. Anurag YadavDr Anurag Yadav
Various causes of DNA damage,
Methods of DNA repair for the Damage to the DNA structure,
Gene regulation and Gene Expression in eukaryotes and Prokaryotes.
Để xem full tài liệu Xin vui long liên hệ page để được hỗ trợ
: https://www.facebook.com/thuvienluanvan01
HOẶC
https://www.facebook.com/garmentspace/
https://www.facebook.com/thuvienluanvan01
https://www.facebook.com/thuvienluanvan01
tai lieu tong hop, thu vien luan van, luan van tong hop, do an chuyen nganh
Bài này mình sưu tầm được, một số phần bị lỗi font. Mình thấy nó khá hay, và có thể giúp ng đọc hiểu được về cơ bản PCR là gì, và cách chạy PCR ra sao.
( Rất cảm ơn người làm bài present này)
PacBio SMRT - THIRD GENERATION SEQUENCING TECHNIQUEMuunda Mudenda
Nucleic acids sequencing is a very powerful molecular biology and biotechnology technique that gives way to discovery, invention, and solutions. This academic document discusses Single-Molecule Real-Time (SMRT) sequencing platform by Pacific Biosciences (PacBio). The doeucment does not claim to exhaust the subject but you will surely get all the needed highlights to understand this technology better. If you would like an in-depth discussion, do not hesitate to write me an email. Enjoy the read.
This is an internship report on molecular biology techniques, which was performed at PERD center under the guidance of Dr. Anshu Srivastava. This pdf contains all the basic information which is a preliminary requisite to know while approaching the molecular biology experimentally.
The next generation sequencing platform of roche 454creativebiogene1
454 is totally different from Solexa and Hiseq of Illumina. The disadvantage of 454 is that it is unable to accurately measure the homopolymer length. For this unavoidable reason, 454 technology will introduce insertion and deletion sequencing errors to the results.
Following our latest publication, The Market for CRISPR/Cas9 Genome Editing Products, released in June 2015 on the Interactive Market Intelligence platform, a follow-up questionnaire was sent to The Science Advisory Board to quantify how the emergence of CRISPR/Cas9 technology is impacting the use of traditional tools and techniques. It was fielded between July 6-8, 2015.
To download, please go to: http://marketanalysts.lifescienceexecutive.com/blog/?p=1995
Bài này mình sưu tầm được, một số phần bị lỗi font. Mình thấy nó khá hay, và có thể giúp ng đọc hiểu được về cơ bản PCR là gì, và cách chạy PCR ra sao.
( Rất cảm ơn người làm bài present này)
PacBio SMRT - THIRD GENERATION SEQUENCING TECHNIQUEMuunda Mudenda
Nucleic acids sequencing is a very powerful molecular biology and biotechnology technique that gives way to discovery, invention, and solutions. This academic document discusses Single-Molecule Real-Time (SMRT) sequencing platform by Pacific Biosciences (PacBio). The doeucment does not claim to exhaust the subject but you will surely get all the needed highlights to understand this technology better. If you would like an in-depth discussion, do not hesitate to write me an email. Enjoy the read.
This is an internship report on molecular biology techniques, which was performed at PERD center under the guidance of Dr. Anshu Srivastava. This pdf contains all the basic information which is a preliminary requisite to know while approaching the molecular biology experimentally.
The next generation sequencing platform of roche 454creativebiogene1
454 is totally different from Solexa and Hiseq of Illumina. The disadvantage of 454 is that it is unable to accurately measure the homopolymer length. For this unavoidable reason, 454 technology will introduce insertion and deletion sequencing errors to the results.
Following our latest publication, The Market for CRISPR/Cas9 Genome Editing Products, released in June 2015 on the Interactive Market Intelligence platform, a follow-up questionnaire was sent to The Science Advisory Board to quantify how the emergence of CRISPR/Cas9 technology is impacting the use of traditional tools and techniques. It was fielded between July 6-8, 2015.
To download, please go to: http://marketanalysts.lifescienceexecutive.com/blog/?p=1995
Next Generation Sequencing & DNA Synthesis: Technology, Consumables Manufactu...Yole Developpement
With the sequencer installed base doubling, the sequencing consumables market will reach $7.8B by 2024.
More information on that report at https://www.i-micronews.com/products/next-generation-sequencing-dna-synthesis-technology-consumables-manufacturing-and-market-trends-2019/
Yaohai Bio-Pharma is the first and the largest biologics CRTDMO (Contract Research, Testing, Development and Manufacturing Organization) focusing on microbial expression system in China, which was established in China Medical City, Taizhou with a 20, 000 square meters plant.
As a one-stop biologics CRTDMO, Yaohai provide customized end-to-end solutions from DNA to drug substance manufacturing and product fill & finish across diversified modalities, such as recombinant proteins, peptides and polypeptides, enzymes, antibody fragments and nano-antibodies, plasmid DNA and mRNA, Glyco-polymers, virus-like particle (VLP), to meet global customers’ clinical and commercial needs in biological drugs, biosimilars, vaccines and diagnostics for human and veterinary use.
https://www.yaohai-bio.com.cn/downloadfile
Best Practices for Validating a Next-Gen Sequencing WorkflowGolden Helix
Validating an NGS workflow is an iterative process that begins with collaboration with personnel and planning protocols for the entire workflow from sample preparation, sequencing and variant calling, all the way to data analysis and reporting. At Golden Helix, while we do not provide pre-validated black-box workflows, we provide our customers with support to validate workflows in a transparent manner, and assist them in reaching production deadlines. This webcast will be led by members of our Field Application Scientist team, and we will explore some of the best practices for NGS workflow validation that we have observed and helped to implement based on real-world examples from our customer base. Key topics for discussion will include:
Sample preparation and collection of adequate case/control data
Designing a robust workflow with special considerations for single versus family analyses and phenotypic considerations
Generating the desired output for clinical or other reports
Real world NGS workflow validation strategies
Tune in for tips and strategies that you can deploy when designing and validating your NGS workflow.
Deeper Insight into Transcriptomes! Download the FlyerQIAGEN
Discover a new workflow for RT-PCR-based gene expression work
Accurate and biologically relevant results in RT-PCR-based
gene expression can be difficult to achieve. Successful
transcriptome work requires validated, reproducible targets
and high-quality technology. Recognizing the variability arising from sample physiology
and pathology, the influence of sample purification and
assay conditions, and the importance of access to easyto-
use software, QIAGEN experts developed a new gene
expression workflow. It will help you properly validate your
RT-PCR and gain the deepest insight into your result.
Accelerate innovation and manufacturing in cell and gene therapy.pptxGenScript ProBio
The rapid expansion of the gene and cell therapy pipeline created constraints to accessing contract capacities around the globe. Innovation in gene and cell therapy expanded many drug development pipelines, and startups that are lacking internal production capacities heavily rely on contract manufacturing organizations (CDMO).
Essentials of Automations: Optimizing FME Workflows with ParametersSafe Software
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Join us for an insightful dive into the world of FME parameters, a critical element in optimizing workflow efficiency. This webinar marks the beginning of our three-part “Essentials of Automation” series. This first webinar is designed to equip you with the knowledge and skills to utilize parameters effectively: enhancing the flexibility, maintainability, and user control of your FME projects.
Here’s what you’ll gain:
- Essentials of FME Parameters: Understand the pivotal role of parameters, including Reader/Writer, Transformer, User, and FME Flow categories. Discover how they are the key to unlocking automation and optimization within your workflows.
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We’ll wrap up with a glimpse into future webinars, followed by a Q&A session to address your specific questions surrounding this topic.
Don’t miss this opportunity to elevate your FME expertise and drive your projects to new heights of efficiency.
Encryption in Microsoft 365 - ExpertsLive Netherlands 2024Albert Hoitingh
In this session I delve into the encryption technology used in Microsoft 365 and Microsoft Purview. Including the concepts of Customer Key and Double Key Encryption.
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Create a campaign using Mailchimp with merge tags/fields
Send an interactive Slack channel message (using buttons)
Have the message received by managers and peers along with a test email for review
But there’s more:
In a second workflow supporting the same use case, you’ll see:
Your campaign sent to target colleagues for approval
If the “Approve” button is clicked, a Jira/Zendesk ticket is created for the marketing design team
But—if the “Reject” button is pushed, colleagues will be alerted via Slack message
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Speakers:
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Charlie Greenberg, Host
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See how to accelerate model training and optimize model performance with active learning
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Get an exclusive demo of the new family of UiPath LLMs – GenAI models specialized for processing different types of documents and messages
This is a hands-on session specifically designed for automation developers and AI enthusiasts seeking to enhance their knowledge in leveraging the latest intelligent document processing capabilities offered by UiPath.
Speakers:
👨🏫 Andras Palfi, Senior Product Manager, UiPath
👩🏫 Lenka Dulovicova, Product Program Manager, UiPath
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The Art of the Pitch: WordPress Relationships and SalesLaura Byrne
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From Siloed Products to Connected Ecosystem: Building a Sustainable and Scala...
GeneMind Introduction.pdf
1. E x p l o r e L i f e ’ s M y s t e r i e s f o r B e t t e r H e a l t h c a r e
2. Company Introduction
Specializing in the independent R&D and manufacturing of
molecular diagnosis technology platform centred on DNA
sequencing system, GeneMind Biosciences is devoted to
constructing a precision medicine ecosystem to serve human
life and health through collaboration with genetic testing
service providers and medical institutions.
GeneMind has launched the single-molecule sequencing
platform GenoCare 1600 and the high-throughput sequencing
platform GenoLab M through independent research and
innovation, and offers the “equipment-reagent-flowcell-
software” total platform solution. GeneMind is one of the
few technology companies with core upstream technology and
independent brand of gene sequencing in the world.
GenoCare 1600 is the world’s first single-molecule
sequencer that has passed medical device clinical trials.
· A high-tech enterprise with core technologies of gene
sequencing and independent intellectual property rights
High-tech
· One of the few independent brands of gene sequencers
in the world
Self-owned brand
· Single-molecule sequencer+ High-throughput sequencing
platform
Volume Production
3. E s t a b l i s h e d i n
Shenzhen, China.
July 2012
S t a r t R & D o f
single-molecule
sequencer.
S e p t e m b e r
2014
T h e f i r s t
principle prototype
of GenoCare single-
molecule sequencing
platform was born.
O c t o b e r
2015
Official completed
the GMP production
line of sequencers
and reagents.
September
2018
G e n o C a r e 1 6 0 0
single-molecule
s e q u e n c e r
successfully passed
the medical device
r e g i s t r a t i o n
inspection of NMPA.
F e b r u a r y
2019
G e n o C a r e h a s
completed medical
d e v i c e c l i n i c a l
t r i a l s , a n d t h e
p o s i t i v e a n d
negative coincidence
rate has reached
100%.
May 2020 The GenoLab high-
t h r o u g h p u t
s e q u e n c i n g
p l a t f o r m w a s
o f f i c i a l l y
launched.
O c t o b e r
2020
Approved to establish
the first provincial
a c a d e m i c i a n
workstation dedicated
to the development of
sequencer platform in
China——Guangdong
A c a d e m i c i a n
workstation.
November
2021
Milestones
4. Core Technologies
Optical System
Hardware
The high sensitivity and high
resolution optical system can
quickly complete the fluorescence
signal acquisition
Base calling algorithm
Software
Complete the output from the
original image information
acquisition to the sequencing
accurately and quickly
Different specifications are
available
Flowcell
High sensitivity; High resolution
Nucleotide analogues and
polymerases
Chemistry
The unique termination base
structure and high fidelity
polymerase provide high precision
detection
5. Products
Able to run one flow cell
alone or two flow cell
simultaneously
Dual flow cell mode
Pre-configured reagent kit
Easy-to-use
Multiple throughput types
available
Flexible
Open to mainstream NGS
libraries
Compatible
Specifications
Flowcell
Two (Able to run one flow cell alone or
two flow cell simultaneously)
Reads/Run
250 M×2(FCM);
500 M×2(FCH)
Read Length SE75、SE150、PE75、PE150
Output/Run 37~150 Gb(FCM);75~300 Gb(FCH)
Turnaround time 13~43 h(FCM);16~53 h(FCH)
Q30 Q30>85%
GenoLab M High-throughput Sequencing Platform
7. I n d e p e n d e n t R & D a n d M a n u f a c t u r i n g C a p a b i l i t y The total area of R&D and production put into use by GeneMind
is nearly 10,000 square meters. The company estalished
sequencer production factory, flowcell laboratory,GMP
production line for kits, organic synthesis laboratory, and
enzyme engineering laboratory. The mass-produced products cover
sequencing instruments, sequencing kits,and flowcell.
· Flowcell Lab
Can be produced by ourselves
· Sequencer Production Line
Annual capacity is 1000 units
· Reagent Kits Production Line
Designed as a GMP workshop to produce kits
for 2.4 million tests annually
·Enzyme Engineering Lab
Independent research and development of
core enzyme
· Organic Synthesis Lab
Able to synthesize our own nucleic acid
and fluorochrome