this ppt is about a Biochip device. in this ppt we add a full knowledge about a biochips.

1. D E S I G N A N D A P P L I C A T I O N O F
D I G I T A L M I C R O F L U I D I C B I O C H I P
Mr. Ravirajsinh Chauhan
Mr. Mitul Patel
BIO TECHNOLOGY
Seminar
20ss02it001
DEV AKABARI

2. AREA,
Biotechnology is a science-driven industry sector that uses
living organisms and molecular biology to produce
healthcare-related products. Biotechnology companies also
develop therapeutics or processes (such as DNA
fingerprinting).
N E X T
BIO TECHNOLOGY

3. TYPES OF BIOCHIP,
D N A c h i p P r o t e i n c h i p E n z y m e c h i p L a b - o n - a - c h i p

4. Lab-on-chip,
Systems for performing biomedical analyses of very
small quantities of liquids
N E X T
Advantages,
- Fast reaction times
- Low-cost, portable and disposable
- Compactness massive parallelization high-
throughput

5. TYPES,
- Continuous-flow: enclosed, interconnecting, micron-
dimension channels
- Digital: discrete droplets of fluid across the surface of
an array of electrodes.
N E X T

6. DIGITAL
MICROFLUIDIC
BIOCHIP,
A biodroplet transportationchemical analysis is based on
several laboratory protocols that require repeated mixing of
samples with reagents. Sample preparation and analyte
identification steps in such bioassays often involve mixing for
solution preparation, i.e., various fluids are to be mixed in a
certain volumetric ratio in their resulting mixture.

7. ADVANTAGES,
It has no moving parts. It requires no channels.
It controls many droplets independently because the electro wetting force is localized
at the surface.
It works with a wide variety of liquids ----- that is, most electrolytic solution. It is
compatible with microscopy.
Glass substrate and transparent indium-tin-oxide (ITO) electrodes makes the chip
compatible with observation from a microscope.

8. Biotech vs.
Pharmaceutical
Biotechnology and pharmaceutical companies both
produce medicines. However, the medicines made by
biotechnology companies are derived from living
organisms while those made by pharmaceutical companies
generally have a chemical basis.
The term biopharma describes companies that use both
biotechnology and chemicals in their research and
development. Common products of biopharmas are
anything made of plastic, laundry detergent, vaccines,
beer, and wine. Common products of pharmaceutical
companies are drugs and vitamins.

9. Biotechnology firms use the processes of living organisms
to solve problems with new products. The use of DNA has
helped to create pest-resistant crops, biofuels like ethanol,
and gene cloning.
On the pharma front, the Cleveland Clinic recognized the
top 10 medical advances for 2021.
These included a new class of drugs for migraines called
calcitonin gene-related peptide (CGRP) and PARP
inhibitors for the treatment of prostate cancer. Also, a new
treatment for postpartum hemorrhage, the vacuum-induced
uterine tamponade, will greatly help women in developing
countries who have limited access to other treatment
options.
Top biotech companies include Exelixis, Novavax, and
Regeneron Pharmaceuticals. Top pharmas include
Johnson & Johnson, Pfizer, and Roche.

10. Biochip is a miniature version of a laboratory, using
which more than hundreds of biochemical reactions
take place simultaneously. They are specially
designed for functioning in a biological environment,
especially inside living organisms. It is not an
electronic device. Biochips consist of millions of
biosensors, which acts as microreactor used for
detecting particular analytes such as an enzyme,
protein, biological molecule and antibody.
BIOCIP,

11. 1. https://www.geeksforgeeks.org/introduction-of-biochip/
2. https://www.ijert.org/the-bio-chips
3. https://www.techopedia.com/definition/14272/biochip
4. https://www.britannica.com/technology/biochip
5. https://whatis.techtarget.com/definition/biochip
REFERENCES

12. THANK
YOU
Seminar
20ss02it001
DEV AKABARI