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Gamete Intrafallopian transfer (GIFT).pdf
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- 2. History In the mid1980s , fertility programs around the world were continuing to struggle with poor success rates for IVF . Although GIFT technically stands for “Gamete Intrafallopian Transfer ” most patients referred to it as putting “Gametes Into the Fallopian Tube”.
- 3. Introduction GIFT can beused to treat many types of infertility, except in cases where there is damage or abnormalities of the both fallopian tubes. These techniques can also be used in cases of male infertility , as long as the sperm is capable of fertilizing an egg .
- 4. If the womanis not capable of producing eggs that can be used in GIFT , but her partner's sperm is capable of fertilization, they might consider getting eggs from a donor.
- 5. Women over age35areless likely to have viable eggs and more likely to have children with birth defects than younger women . One reason for using an egg donor is age.
- 6. A woman withpremature ovarian failure, a condition in which menopause has begun early, might also consider a donor if she wants to carry a child. Most egg donation is anonymous, but some couples prefer to know their egg donor and take legal steps to contract for the donation of the eggs.
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- 8. PRE-EXAMINATION OF THECONCEIVING SURROUNDING IN WOMEN’S BODY: After showing interest in GIFT treatment, the fertility expert will examine you and an X-ray will be taken to determine the health status of your Fallopian tubes.
- 9. In other cases,there must at least be one healthy Fallopian tube for the procedure to be conducted. A laparoscopy will be performed to check the Fallopian tubes or determine the presence of scar tissue on the outside wall.
- 10. CHECKING OF MAN’SSPERMS: Adjoining process of man sperm count is checked to determine if proper health sperms are there to carry forward the fertilization process.
- 11. OVULATION AND EGG RETRIEVAL: Medications are givento female counterpart so that multiple mature eggs can be formed. The follicles are monitored every two days so that proper formation of eggs can be well monitored.
- 12. After having fertilitydrugs or natural ovulation, the well-formed timely eggs will be retrieved through a laparoscopic surgery by extracting the eggs from the follicles and your male partner will provide sperms on the same day in case donor sperms aren’t necessary. Normally 8 – 16 eggs are retrieved at this time.
- 13. FERTILIZATION PROCESS: This processis carried out by Embryologist After mixing the eggs and the sperms, they will be transferred back into the woman’s body via her vagina with the help of a catheter.
- 14. SURGICAL PROCESS TO TRANSFERTHE EGGS AND SPERMS: Through laparoscopy and making a small incision on stomach, the eggs and sperm mixture from the catheter is transferred into one of the fallopian tube.
- 15. SUCCESSFUL IMPLANTATION SIGNALIS SIGNALED WITH EMBRYO FORMATION If after transferring the mixture of eggs and sperms, an embryo is formed after few days, then if implantation is successful then pregnancy rates increases.
- 16. The woman is additionallyplaced on medications that facilitate to make the female internal reproductive organ lining to facilitate implantation throughout this era.
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- 18. A gamete intra-fallopiantransfer can be fully completed inoneand ahalfmonths. This includes the entire process beginning from the initiation of the hormonal therapy and right until implantation. The surgical procedure alone would take a little more thaneight hours, and you can go back home on the same day as the operation.
- 19. TAKE A PREGNANCY TEST: Pregnancy testcan be done two weeks after surgery.
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- 24. ZIFT and GIFTmay not be available in all areas. These procedures cost approximately $15,000 to $20,000 for each attempt. In vitro fertilization usually costs less.
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- 26. The GIFT procedure provides abelief of natural conception with the fact that fertilization takes place inside the body of a woman than in the laboratory dish.
- 27. It is muchmore affordable than IVF and with that, a couple can easily foot the GIFT treatment cost in India than other ART treatments.
- 28. It is aconvenient procedure since it requires no hospitalization or extensive fertility workout . There are many couples out there who are unable to conceive despite earnest and dedicated attempts.
- 29. The advancement inthe field of medicine has made available the assisted reproductive technology (ART). But how can one determine as to which one is the best for them? IVF, ZIFT, and GIFT- all have their pros and cons.
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- 31. There is achance of multiple pregnancies if more than one egg is used. This can lead to a miscarriage or financial/emotional burden of raising more kids than initially intended.
- 32. It is invasivedue to the use of a laparoscopy which increases the chance of complications. There is a risk of ectopic pregnancy where the egg gets implanted outside the uterus.
- 33. Babies born usingthis method have a higher susceptibility to congenital disabilities. There is a chance that the treatment does not work. The procedure relies on the same methods used for IVF in ovary simulation.
- 34. If you haveexperienced ovarian hyperstimulation during IVF, there is a chance that you will experience the same with GIFT . While rare, there is a small chance of infection that can develop during this surgery.
- 35. There is novalidation method to know if fertilization has taken place. The entire process is time-consuming and expensive.
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- 37. Gamete intrafallopian transfer isnot technically in vitro fertilization because with GIFT, fertilization takes place inside the body, not on a petri dish.
- 38. As with mostfertility procedures, success depends on the couple's age and the Success rate .
- 39. woman's egg quality. Itis estimated that approximately 25–30% of GIFT cycles result in pregnancy , with a third of those being twins or triplets, etc.
- 40. Some Catholic moral theologiansare nevertheless concerned with it because they "consider this to be a replacement of the marital act, and therefore immoral."
- 41. The First GIFT babyin the US was Kaitlynne Kelley born on 28 April 1987.
- 42. • In Venezuela,the first GIFT babies were Luis Hernández, Rosa Helena Hernández and Luisa Hernández , who were born on 24 June 1987 and were also the first triplets to be born using the GIFT method.
- 43. • The firstapplication of this method in Latin America was held in Argentina on 13 May 1986, and was led by Dr. Ricardo Asch , the treatment was successfully completed with the birth of Manuel Campo Lopez .