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Gall stones
Hossam GHONEIM, MD
Risk factors
• Age
• Sex
• Pregnancy
• Oral contraceptives and estrogen replacement therapy
• Family history and genetics
• Obesity
• Rapid weight loss
• Diabetes mellitus
• Serum lipids
• Serum bilirubin
• Cirrhosis
• Gallbladder stasis
• Other drugs
• Decreased physical activity
• Crohn's disease
• Hemolysis
Clinical presentation
• Typical
– Severe pain, Intermittent and recurrent upper abd
mainly rt hypochondrium, refered to Rt shoulder
and/or back
– Nausea, vomiting, fever
• Atypical
– NCCP, epigastric pain, reflux and Heart burn
• Murphy’s sign on clinical examination
Diagnosis
• Ultrasound
• MRCP
• Lab
– CBC
– CRP
– Bilirubin, ALT,AST
FAQ
• Inflammation or no Inflammation (silent
stones)?
• Type of stones or number and size?
• CBD stones, MRCP or ERCP?
• GS pancreatitis
• Non calcular cholecystitis
• GB polyps
• GB dyskinesia
GS ilieus

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Gall stones

  • 2. Risk factors • Age • Sex • Pregnancy • Oral contraceptives and estrogen replacement therapy • Family history and genetics • Obesity • Rapid weight loss • Diabetes mellitus • Serum lipids • Serum bilirubin • Cirrhosis • Gallbladder stasis • Other drugs • Decreased physical activity • Crohn's disease • Hemolysis
  • 3. Clinical presentation • Typical – Severe pain, Intermittent and recurrent upper abd mainly rt hypochondrium, refered to Rt shoulder and/or back – Nausea, vomiting, fever • Atypical – NCCP, epigastric pain, reflux and Heart burn • Murphy’s sign on clinical examination
  • 4. Diagnosis • Ultrasound • MRCP • Lab – CBC – CRP – Bilirubin, ALT,AST
  • 5.
  • 6.
  • 7.
  • 8.
  • 9. FAQ • Inflammation or no Inflammation (silent stones)? • Type of stones or number and size? • CBD stones, MRCP or ERCP? • GS pancreatitis • Non calcular cholecystitis • GB polyps • GB dyskinesia