Free radical-pharmacology

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Free radicals are highly reactive molecules that can damage cells. The field of free radical pharmacology studies how free radicals influence health and disease, and how antioxidants may help reduce oxidative stress. Research suggests free radicals play a role in aging and diseases like cancer, while antioxidants in fruits and vegetables may help counter the effects of free radicals in the body.

Alternative methods to animals testing are the development and implementation of test method that avoid use of live animals or use of less animals in method. The council directive on protection of animals used for experiments and scientific purpose in article 23 “The commission and member states should encourage research into development and validation of alternative methods which could provide the same level of information as that obtained in experiment using animals but which involves less animal”. Alternative methods able to do: Reduce Refine Replace collectively called as “The 3Rs Principle”. Needs for alternative methods Because in laboratory animals may be: Poisoned. Deprived of food water and sleep. Applied with skin and eye irritants. Subjected to psychological stress. Deliberately infected with the infected disease.

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