This document discusses energy, metabolism, and how the body uses food for fuel. It covers the following key points:
1. Energy is measured in kilojoules and kilocalories, and is required for life processes like heart function, organ function, temperature regulation, and muscle movement. Different people need varying amounts depending on age, gender, size, activity level, and genes.
2. Energy comes from carbohydrates, proteins, and fats in food. Carbohydrates and proteins provide 4 calories per gram while fat provides 9 calories per gram, making it the most energy dense.
3. Basal metabolic rate is the minimum energy needed for basic body functions at rest. It can
This presentation talks about energy balance, shows how to calculate your total energy expenditure and explains the different Dietary Reference Intakes (DRIs).
Food, Nutrition, Nutrients, Diet, Energy consumption & BMIDr.Subir Kumar
Chemistry of nutrition, Dietary principles of food, Basic energy consumption, Total calorie requirements, Energy providing foods, Nutrition balance, Body mass index
This presentation talks about energy balance, shows how to calculate your total energy expenditure and explains the different Dietary Reference Intakes (DRIs).
Food, Nutrition, Nutrients, Diet, Energy consumption & BMIDr.Subir Kumar
Chemistry of nutrition, Dietary principles of food, Basic energy consumption, Total calorie requirements, Energy providing foods, Nutrition balance, Body mass index
Knee anatomy and clinical tests 2024.pdfvimalpl1234
This includes all relevant anatomy and clinical tests compiled from standard textbooks, Campbell,netter etc..It is comprehensive and best suited for orthopaedicians and orthopaedic residents.
These simplified slides by Dr. Sidra Arshad present an overview of the non-respiratory functions of the respiratory tract.
Learning objectives:
1. Enlist the non-respiratory functions of the respiratory tract
2. Briefly explain how these functions are carried out
3. Discuss the significance of dead space
4. Differentiate between minute ventilation and alveolar ventilation
5. Describe the cough and sneeze reflexes
Study Resources:
1. Chapter 39, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 34, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 17, Human Physiology by Lauralee Sherwood, 9th edition
4. Non-respiratory functions of the lungs https://academic.oup.com/bjaed/article/13/3/98/278874
Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
Prix Galien International 2024 Forum ProgramLevi Shapiro
June 20, 2024, Prix Galien International and Jerusalem Ethics Forum in ROME. Detailed agenda including panels:
- ADVANCES IN CARDIOLOGY: A NEW PARADIGM IS COMING
- WOMEN’S HEALTH: FERTILITY PRESERVATION
- WHAT’S NEW IN THE TREATMENT OF INFECTIOUS,
ONCOLOGICAL AND INFLAMMATORY SKIN DISEASES?
- ARTIFICIAL INTELLIGENCE AND ETHICS
- GENE THERAPY
- BEYOND BORDERS: GLOBAL INITIATIVES FOR DEMOCRATIZING LIFE SCIENCE TECHNOLOGIES AND PROMOTING ACCESS TO HEALTHCARE
- ETHICAL CHALLENGES IN LIFE SCIENCES
- Prix Galien International Awards Ceremony
The prostate is an exocrine gland of the male mammalian reproductive system
It is a walnut-sized gland that forms part of the male reproductive system and is located in front of the rectum and just below the urinary bladder
Function is to store and secrete a clear, slightly alkaline fluid that constitutes 10-30% of the volume of the seminal fluid that along with the spermatozoa, constitutes semen
A healthy human prostate measures (4cm-vertical, by 3cm-horizontal, 2cm ant-post ).
It surrounds the urethra just below the urinary bladder. It has anterior, median, posterior and two lateral lobes
It’s work is regulated by androgens which are responsible for male sex characteristics
Generalised disease of the prostate due to hormonal derangement which leads to non malignant enlargement of the gland (increase in the number of epithelial cells and stromal tissue)to cause compression of the urethra leading to symptoms (LUTS
Recomendações da OMS sobre cuidados maternos e neonatais para uma experiência pós-natal positiva.
Em consonância com os ODS – Objetivos do Desenvolvimento Sustentável e a Estratégia Global para a Saúde das Mulheres, Crianças e Adolescentes, e aplicando uma abordagem baseada nos direitos humanos, os esforços de cuidados pós-natais devem expandir-se para além da cobertura e da simples sobrevivência, de modo a incluir cuidados de qualidade.
Estas diretrizes visam melhorar a qualidade dos cuidados pós-natais essenciais e de rotina prestados às mulheres e aos recém-nascidos, com o objetivo final de melhorar a saúde e o bem-estar materno e neonatal.
Uma “experiência pós-natal positiva” é um resultado importante para todas as mulheres que dão à luz e para os seus recém-nascidos, estabelecendo as bases para a melhoria da saúde e do bem-estar a curto e longo prazo. Uma experiência pós-natal positiva é definida como aquela em que as mulheres, pessoas que gestam, os recém-nascidos, os casais, os pais, os cuidadores e as famílias recebem informação consistente, garantia e apoio de profissionais de saúde motivados; e onde um sistema de saúde flexível e com recursos reconheça as necessidades das mulheres e dos bebês e respeite o seu contexto cultural.
Estas diretrizes consolidadas apresentam algumas recomendações novas e já bem fundamentadas sobre cuidados pós-natais de rotina para mulheres e neonatos que recebem cuidados no pós-parto em unidades de saúde ou na comunidade, independentemente dos recursos disponíveis.
É fornecido um conjunto abrangente de recomendações para cuidados durante o período puerperal, com ênfase nos cuidados essenciais que todas as mulheres e recém-nascidos devem receber, e com a devida atenção à qualidade dos cuidados; isto é, a entrega e a experiência do cuidado recebido. Estas diretrizes atualizam e ampliam as recomendações da OMS de 2014 sobre cuidados pós-natais da mãe e do recém-nascido e complementam as atuais diretrizes da OMS sobre a gestão de complicações pós-natais.
O estabelecimento da amamentação e o manejo das principais intercorrências é contemplada.
Recomendamos muito.
Vamos discutir essas recomendações no nosso curso de pós-graduação em Aleitamento no Instituto Ciclos.
Esta publicação só está disponível em inglês até o momento.
Prof. Marcus Renato de Carvalho
www.agostodourado.com
Explore natural remedies for syphilis treatment in Singapore. Discover alternative therapies, herbal remedies, and lifestyle changes that may complement conventional treatments. Learn about holistic approaches to managing syphilis symptoms and supporting overall health.
Pulmonary Thromboembolism - etilogy, types, medical- Surgical and nursing man...VarunMahajani
Disruption of blood supply to lung alveoli due to blockage of one or more pulmonary blood vessels is called as Pulmonary thromboembolism. In this presentation we will discuss its causes, types and its management in depth.
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NVBDCP.pptx Nation vector borne disease control programSapna Thakur
NVBDCP was launched in 2003-2004 . Vector-Borne Disease: Disease that results from an infection transmitted to humans and other animals by blood-feeding arthropods, such as mosquitoes, ticks, and fleas. Examples of vector-borne diseases include Dengue fever, West Nile Virus, Lyme disease, and malaria.
2. Energy is the ability to do work. It is measured in kilojoules (kJ) and kilocalories
(kcals). We all need energy to grow, stay alive, keep warm and be active. Energy is
essential for life, and is required to fuel many different body processes, growth and
activities.
These include:
• keeping the heart beating;
• keeping the organs functioning;
• maintenance of body temperature;
• muscle contraction.
3. Different people need different amounts of dietary energy
depending on the following:
• age;
• gender;
• body size;
• level of activity;
• genes.
4. Energy is provided by the carbohydrate, protein and fat in the food and drink we
consume.
These are known as macronutrients.
The amount of energy that each of these macronutrients provides varies.
5. Definition of terms
Calorie: unit used to measure energy
Kilocalorie is a unit of energy commonly used to express
energy value of food.
Food energy is the amount of energy in food that is a
available through digestion. The energy value of food
indicates its value to the body as fuel.
6. Kilocalories come from foods and beverages
• Bomb calorimeter used in laboratories to measure
kilocalories in foods and beverages
- Results must be adjusted for the physiological fuel
values
• Nutrition analysis software or food composition tables
can estimate energy in
- Carbohydrate and Protein: 4 kcal/gram
- Fat: 9 kcal/gram
- Alcohol: 7 kcal/gram
7. Energy
Energy intake is measured in joules (J) or kilojoules (kJ), but many people
are more familiar with Calories (kcal).
1 kilojoule (kJ) = 1,000 joules
1 megajoule (MJ) = 1,000,000 joules
1 kilocalorie (kcal) = 1,000 calories
To convert from one unit to another:
1 kcal = 4.184 kJ
Therefore, a 2000-kcal diet
provides 8.368 MJ or 8368 kJ
1 MJ = 239 kcal
8. Carbohydrate (starch and sugars) provides 3.75 kcal (16 kJ) per gram (for the
purposes of food labelling this is rounded up to 4 kcal (17kJ) per gram).
Protein provides 4kcal (17kJ) per gram.
Fat is the most energy dense nutrient, providing 9kcal (37kJ) per gram.
Energy intake can be estimated by applying these figures to the amount of
carbohydrate, protein and fat we consume from food and drink.
Alcohol also provides energy at 7kcal (29kJ) per gram.
10. Which of these foods do you think contributes the most energy per 100g?
Total Energy: 1135.5kJ
Carbohydrate 982.6kJ
Protein 170.0kJ
Fat 66.6kJ
Total Energy: 3696.0kJ
Carbohydrate 0.0kJ
Protein 0.0kJ
Fat 3696.0kJ
Total Energy: 450.9kJ
Carbohydrate 17.0kJ
Protein 312.8kJ
Fat 122.1kJ
Energy in food and drinks
11. How much energy do we need?
Energy requirements vary from person to person,
depending on the Basal Metabolic Rate (BMR) and
Physical Activity Level (PAL).
Total energy expenditure (TEE) =
BMR x PAL
12. What Is Energy Balance and Why Is It
Important?
Energy balance is achieved when the kilocalories consumed
equal the kilocalories expended
13. Energy Balance
Energy balance can be maintained by:
• regulating energy intake through the diet;
• adjusting physical activity levels;
• a combination of both.
Energy in:
food and
drinks
Energy
out:
activity
Energy in = Energy out = Energy balance
15. A person is said to be in positive energy balance when the
diet provides more energy than is needed to meet energy
demands of the body. Energy is stored as fat and the
person puts on weight over time.
People who achieve a positive energy balance over an
extended period of time are likely to become overweight
or obese.
Being overweight or obese is associated with an increased
risk of developing certain cancers, cardiovascular disease
and type 2 diabetes.
Positive energy balance
Energy in:
food and
drinks
Energy
out:
activity
Energy in > Energy out = Weight gain
16. A person is said to be in negative energy balance when
there is insufficient energy from the diet to meet energy
demands of the body. Energy is derived from energy
stores and the person loses weight.
People who achieve a negative energy balance over an
extended period of time are likely to become
underweight.
Being underweight is associated with health problems,
such as osteoporosis (low bone mass), infertility
(difficulty to conceive) and even heart failure.
Negative energy balance
Energy
in: food
and
drinks
Energy
out:
activity
Energy out > Energy in = Weight loss
17. Experts have estimated the average requirements for energy for
different types of people.
These figures are known as Estimated Average Requirements (EAR)
for energy.
It is also recommended that:
• about 50% of our energy intake should come from carbohydrate;
• no more than 35% of our energy intake should come from fat.
That means around 15% of our energy intake should come from protein.
Dietary reference values
18. Estimated average requirements (EARs) vary throughout life.
Babies, young children and teenagers need more energy in
relation to their size to grow and be active.
After the age of 18, energy requirements decrease and remain
the same until 50, but actual needs depend on people’s activity
levels.
Energy requirements for older adults decrease as activity levels
fall, and there is a reduction in the basal metabolic rate.
Estimated average requirements
20. EARs - adults
Years Men (MJ) Men (kcal) Women (MJ) Women (kcal)
19-24 11.6 2772 9.1 2175
25-34 11.5 2749 9.1 2175
35-44 11.0 2629 8.8 2103
45-54 10.8 2581 8.8 2103
55-64 10.8 2581 8.7 2079
65-74 9.8 2342 8.0 1912
75+ 9.6 2294 7.7 1840
Why do you think there is a difference in requirements for males and females?
What effect would increasing activity levels have on the energy requirements?
21. Metabolic Rate
• It is the rate of energy production within the body.
• ATP molecules are the unit of biologic energy. ATP is converted to ADP to
release energy, which is needed for all bodily functions, such as cell division,
contraction of muscles, maintaining body temperature, movement of fluids
etc.
• ATP can be synthesized from energy molecules (carbohydrate, protein and
fat) aerobically or anaerobic ally.
• The rate of ATP production (to perform the bodily functions) is closely
coordinated with cardiovascular response.
• Higher ATP consumption rate higher is oxygen consumption rate and higher
the cardiac output.
22. What is basal metabolic rate?
Basal metabolic rate (BMR) is the rate at which a person uses
energy to maintain the basic functions of the body when it is at
complete rest, such as:
• breathing;
• keeping warm;
• keeping the heart beating
23. Unit of energy production (metabolism)
• Basic unit of energy = Force x distance = 1N x 1m = 1 Joule
• Energy content in food is given in terms of Kcal (commonly referred as
Calorie).
• Kcal is the amount of energy needed to raise the temp of 1 kg of water by 10
C.
• 1 Joule = 0.000239 kcal
• 1 kcal = 1/0.000239 J = 4184 J
• Rate of energy consumption = 1 Joule/sec = 1 watt
• 1 kcal/hr = 1/3600 Kcal/sec = 4184/3600 J/sec = 1.16 watt
24. Basal Metabolic rate
Energy metabolism needed to maintain body temperature
and body functions (regeneration of cells, respiration,
circulation etc) at rest.
– 1.28 W/kg for males,
– 1.16 W/kg for females (higher percent of fat do not need
metabolism).
– Children have higher surface to volume ratio more heat loss,
also higher growth rate so they have higher basal metabolic
rate.
25. Factors that Affect Basal Metabolic Rate
Exercise: This is one of the biggest factors
that influence BMR.
BMR is higher in people who exercise
regularly
26. Hormones: an increase in thyroid hormones increases
BMR, decreased levels of the hormone lower BMR
Body Temperature: Excessive heat or cold raise BMR
27. Gender: Males tend to have higher basal metabolism than
females due to an abundance of hormones such as
testosterone ad elevated levels of muscle mass compared to
females
Age: as we get older basal metabolic rate becomes
increasingly slower.
28. Surface Area: Taller individuals have a higher BMR
compared to shorter individuals. More surface area
means more heat lost from the body, which causes the
metabolism to speed up in order to maintain body
temperature.
29. Stress and Illness: increase in hormone activity due to
physical or physiological stress increase BMR.
Starvation: Fasting for more than 48 hrs. will lead to a
decrease of 50% of Basal Metabolic Rate.
30.
31. Body mass index (BMI)
Body Mass Index (BMI) can be used to
identify if an adult is a correct weight for
height.
BMI can be calculated as follows:
BMI = weight (kg)
(height in m)2
Recommended BMI range (adults)
Less than 18.5 Underweight
18.5 to 25 Desirable or healthy
range
25-30 Overweight
30-35 Obese (Class I)
35-40 Obese (Class II)
Over 40 Morbidly or severely
obese (Class III)
33. Health Risks Associated with Body Weight and Body
Composition
Being overweight increases health risks
• Overweight and obesity associated with increased risk of
heart disease, hypertension, stroke, hyperlipidemia,
gallstones, sleep apnea, and reproductive problems
• Increases risk of certain cancers including colon, breast,
endometrial, and gallbladder cancer
• More than 80% of people with type 2 diabetes are
overweight
• Metabolic syndrome is associated with central obesity
34. Health Risks Associated with Body Weight and Body
Composition
Being underweight also increases health risks
• Symptomatic of malnutrition, substance abuse, or disease
• Higher risk of anemia, osteoporosis and bone fractures,
heart irregularities, and amenorrhea
• Correlated with depression and anxiety, inability to fight
infection, trouble regulating body temperature, decreased
muscle strength, and risk of premature death
• May be unintentional and due to malabsorption
associated with diseases such as cancer, inflammatory
bowel disease, or celiac disease
36. Activity Metabolism
Activity Metabolism increases with physical
exertion level. This is due to increase demand of
ATP from muscle contraction, increase work of
ventilation, increased work by the heart muscle.
Population values for Activity Metabolic Rates for
various industrial tasks are available or can be
predicted for job design purposes.
Kcal/hr kcal/min
Light 0-189 0-3.15
Moderate 189-300 3.15-5
Heavy over 300 over 5
37. RESPONSE TO EXERCISE
To match the energy demand for work, adjustment occurs in
1. Heart Rate – varies from resting 70 bpm to maximum (220-age)
2. Stroke Volume – increases gradually up to 40% for Maximal Voluntary Contraction.
3. A-V difference in O2 concentration –
resting arterial 19 mL/100 mL, venous 15 mL/100 mL
In extreme situation venous O2 concentration can drop to 6 mL/100 mL
4. Blood redistribution
5. Blood Pressure
6. Breathing rate
7. Ventilation
Each of these physical responses can be used to measure physical work load.
38. Heart rate and
activity metabolism rate
• Oxygen uptake rate during exercise provides good estimator of ATP use,
hence the metabolic rate.
• In normal physical work, cardiac output (amount of blood pumped per
minute) also matches the oxygen supply needed for a workload.
• Cardiac Output = Heart Rate (/Min) *Stroke Volume (liters) liters/min.
• For an individual Stroke Volume is affected by the intensity of exercise. SV
increases with exercise intensity and reaches its maximum level for an
exercise of about 40% of ones maximum aerobic capacity. For an individual,
it also changes with body posture.
• Heart Rate is an excellent predictor of workload or cardiovascular load for
moderate to heavy intensity physical work.
39. Heart rate and
level of work intensity
• Heart Rate is effected by:
– (i) Emotions especially at low metabolic level.
– (ii) Ambient temperature
– (iii) Exercise intensity
• When using heart rate for light work, other factors needs to be
controlled appropriately.
• For lighter type of tasks also HR is often used to compare exertion
levels of two tasks.
• Heart rate measurement is comparatively easy and often used in
Ergonomics studies to compare physiological costs of work.
40. Classification of physical work intensity
Type of
work
Kcal/Hr Kcal/min
O2 uptake
L/min
HR
(bpm)
Light 0-189 0-3.15 .5 90
Moderate 189-300 3.15-5 .5-.99 90-110
Heavy 300+ 5+ 1-1.49 110-130
41. MEASURMENT OF CARDIOVASCULAR LIMITS OF AN
INDIVIDUAL
• VO2 max in mL/kg- min is a determinant of ones cardiovascular
capacity or fitness level.
• It can be measured in laboratory
• Type of task to determine VO2max also has an influence on VO2
max. Larger muscle group used, produces larger values of VO2
max.
• VO2 max varies with fitness level and age
42.
43. Effect of mental workload on HR
• Response to mental workload, Heart Rate variability
(sinus arrhythmia) is reduced with higher mental
workload.
44. 2009
Energy Imbalance
Effects in the Body
Excess energy is stored in fat cells, which enlarge or multiply.
Enlargement of fat cells is known as hypertrophy,
whereas multiplication of fat cells is known as hyperplasia.
With time, excesses in energy storage lead to obesity.
Fat cells
J La State Med Soc .2005; 156 (1): S42-49.
45. 2009
Fat Cell Enlargement
Hypertrophy
Enlarged fat cells produce the
clinical problems associated with obesity,
due to the following:
The weight or mass of the extra fat
The increased secretion of free fatty acids
and peptides from enlarged fat cells.
J La State Med Soc .2005; 156 (1): S42-49.
46. 2009
Obstructive sleep apnea
Osteoarthritis
Cardiovascular disorders
Gastrointestinal
disorders
Metabolic disorders
Endometrial, prostate
and breast cancers
Complications of pregnancy
Menstrual irregularities
Psychological disorders
Individuals who are obese are at a greater risk of developing:
Morbidity
Associated with Obesity
CDC