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Final Exam English II
International Spread of The COVID-19 Outbreak
REYNALDI
20160700011
STUDY PROGRAM INFORMATION SYSTEMS
FACULTY OF SCIENCE AND TECHNOLOGY
UNIVERSITAS BUDDHI DHARMA
Beginning in December 2019, Chinese health authorities have been closely monitoring
a cluster of pneumonia cases in the city of Wuhan in Hubei province, China. The pathogen that
causes the viral pneumonia in affected individuals is the newly recognized coronavirus known
as severe acute respiratory syndrome–coronavirus 2 (SARS-CoV-2) (WHO, 2020). Early
reports predicted the onset of a potential Coronavirus outbreak given the estimate of a
reproduction number for the 2019 Novel (New) Coronavirus (COVID-19, named by WHO on
Feb 11, 2020) which was deemed to be significantly larger than 1 (ranges from 2.24 to 3.58)
(S. Zhao, etc 2020).
As of January 30, 2020, 7734 cases have been confirmed in China and 90 other cases
have also been reported from a number of countries that include Taiwan, Thailand, Vietnam,
Malaysia, Nepal, Sri Lanka, Cambodia, Japan, Singapore, Republic of Korea, United Arab
Emirates, United States, The Philippines, India, Australia, Canada, Finland, France, and
Germany. The case fatality rate was calculated to be 2.2% (170/7824) (M. Bassetti, etc 2020).
Patients infected with COVID-19 showed higher leukocyte numbers, abnormal respiratory
findings, and increased levels of plasma pro-inflammatory cytokines. One of the COVID-19
case reports showed a patient at 5 days of fever presented with a cough, coarse breathing sounds
of both lungs, and a body temperature of 39.0 °C. The patient's sputum showed positive real-
time polymerase chain reaction results that confirmed COVID-19 infection (J. Lei, etc 2020).
Based on the large number of infected people that were exposed to the wet animal
market in Wuhan City where live animals are routinely sold, it is suggested that this is the
likely zoonotic origin of the COVID-19. Efforts have been made to search for a reservoir host
or intermediate carriers from which the infection may have spread to humans. Initial reports
identified two species of snakes that could be a possible reservoir of the COVID-19. However,
to date, there has been no consistent evidence of coronavirus reservoirs other than mammals
and birds (M. Bassetti, 2020 & W. Ji, 2020).
Starting in early February 2020, 59 airline companies suspended or limited flights to
mainland China, and several countries—including the United States, Russia, Australia, and
Italy—have imposed government-issued travel restrictions (New York Times, 2020). this is
done to prevent the spread of the virus from becoming more widespread.
The experts have done several analyzes and the analysis of the COVID-19 outbreak and
the modeling assessment of the effects of travel limitations could be beneficial to national and
international agencies for public health response planning. We show that, by January 23, 2020,
the epidemic has already spread to other cities within mainland China. The travel quarantine
around Wuhan has only modestly delayed the spread of disease to other areas of mainland
China. This finding is consistent with the results of separate studies on the diffusion of SARS-
CoV-2 in mainland China (H. Tian, etc, 2020).
The person-to-person transmission of COVID-19 infection led to the isolation of
patients that were administered a variety of treatments. At present, there are no specific
antiviral drugs or vaccine against COVID-19 infection for potential therapy of humans. The
only option available is using broad-spectrum antiviral drugs like Nucleoside analogues and
also HIV-protease inhibitors that could attenuate virus infection until the specific antiviral
becomes available (H. Lu Drug, 2020). With 3405 deaths from covid-19, Italy’s fatalities now
exceed those of China. There were 427 deaths in the 24 hours until 6 pm on 19 March,
according to Italy’s civil protection chief Angelo Borrelli. China’s death toll is 3245. Two
doctors died from the covid-19 in Como on 19 March, according to the federation of Italian
doctors’ guilds. They were respiratory specialist Giuseppe Lanati and family doctor Luigi
Frusciante, both of whom had come out of retirement to work during the emergency. There
have now been 13 deaths among Italian doctors, the federation said. (Day, Michael, 2020).
Extensive measures to reduce person-to-person transmission of COVID-19 are required
to control the current outbreak. Special attention and efforts to protect or reduce transmission
should be applied to susceptible populations including children, health care providers, and
elderly people. A guideline was published for the medical staff, healthcare providers, and,
public health individuals and researchers who are interested in the 2019-nCoV (Y.H. Jin, L,
etc, 2020).Also it has been reported that some of the Asian populations are more susceptible to
acquire this COVID-19 infection when compared to the other races populations (Xu, 2020).
Following are the protective measures given by WHO (2020d),
1. Wash hands completely using an alcohol-based hand sanitizer will kill the virus,
2. Avoid touching eyes, nose and mouth when outside.
3. Be updated about the virus.
4. Avoid travelling or gathering in crowded places.
5. Women with infants are encouraged to breastfeed their babies to enhance their
immunity.
WHO is coordinating efforts to develop vaccines and medicines to prevent and treat
COVID-19 (WHO, 2020d). National Institutes of Health (NIH), has mentioned that SARS-
CoV-2 could survive for up to 3 h maximum as aerosols to a maximum of three days on
surfaces. Slowing the spread of the COVID-19 cases will significantly reduce the strain on the
healthcare system of the country by limiting the number of people who are severely sick by
COVID-19 and need hospital care. It will also give researchers more time to develop the
vaccine against COVID-19. So, it's time for all the citizens to join hands together to fight
against coronavirus by practicing self-hygiene and social distancing (Balachandar Vellingir,
etc, 2020).
It is hoped that with our health and hygiene we will be able to release us from the
COVID-19 virus and a vaccine for this virus can be found soon, and we can return to our daily
lives without fearing overshadowed by this virus.
REFERENCES
World Health Organization (WHO), “Novel Coronavirus – China” (WHO, 2020);
www.who.int/csr/don/12-january-2020-novel-coronavirus-china/en/.
S. Zhao, Q. Lin, J. Ran, S.S. Musa, G. Yang, W. Wang, et al. Preliminary estimation of the
basic reproduction number of novel coronavirus (2019-nCoV) in China, from 2019 to 2020: a
data-driven analysis in the early phase of the outbreak. 92 (2020), pp. 214-217, https://doi.org
/10.1016/j.ijid.2020.01.050
M. Bassetti, A. Vena, D. Roberto Giacobbe The Novel Chinese Coronavirus (2019-nCoV)
Infections: challenges for fighting the storm Eur. J. Clin. Invest. (2020), Article e13209,
https://doi.org /10.1111/eci.13209
J. Lei, J. Li, X. Li, X. Qi CT imaging of the 2019 novel coronavirus (2019-nCoV) pneumonia
Radiology (2020), p. 200236, https://doi.org/10.1148/radiol.2020200236
M. Bassetti, A. Vena, D. Roberto Giacobbe The Novel Chinese Coronavirus (2019-nCoV)
Infections: challenges for fighting the storm Eur. J. Clin. Invest. (2020), Article e13209,
https://doi.org /10.1111/eci.13209
W. Ji, W. Wang, X. Zhao, J. Zai, X. Li Homologous recombination within the spike
glycoprotein of the newly identified coronavirus may boost cross-species transmission from
snake to human J. Med. Virol., 92 (4) (2020), pp. 433-440, https://doi.org/10.1002/jmv.25682
New York Times, “North Korea Bans Foreign Tourists Over Coronavirus, Tour Operator Says”
(2020); https://www.nytimes.com/2020/01/21/world/asia/coronavirus-china-north-korea-
tourism-ban.html
H. Tian, Y. Liu, Y. Li, C.-H. Wu, B. Chen, M. U. G. Kraemer, B. Li, J. Cai, B. Xu, Q. Yang,
B. Wang, P. Yang, Y. Cui, Y. Song, P. Zheng, Q. Wang, O. N. Bjornstad, R. Yang, B. Grenfell,
O. Pybus, C. Dye, The impact of transmission control measures during the first 50 days of the
COVID-19 epidemic in China. medRxiv https://doi.org/2020.01.30.20019844 [Preprint]. 10
March 2020. https://doi.org/10.1101/2020.01.30.20019844
H. Lu Drug treatment options for the 2019-new coronavirus (2019-nCoV) Biosci. Trends
(2020), https://doi.org/10.5582/bst.2020.01020
Day, Michael.BMJ : British Medical Journal (Online); London Vol. 368, (Mar 23, 2020).
https://doi.org/10.1136/bmj.m1165
Y.H. Jin, L. Cai, Z.S. Cheng, H. Cheng, T. Deng, Y.P. Fan, et al. A rapid advice guideline for
the diagnosis and treatment of 2019 novel coronavirus (2019-nCoV) infected pneumonia
(standard version) Mil. Med. Res., 7 (2020), p. 4
Y. Xu Unveiling the origin and transmission of 2019-nCoV Trends Microbiol., 28 (2020), pp.
239-240, https://doi.org/10.1016/j.tim.2020.02.001
World Health Organization (WHO) Surveillance case definitions for human infection with
novel coronavirus (nCoV) (2020) https://apps.who.int/iris/handle/10665/330376
COVID-19: A promising cure for the global panic Balachandar Vellingir, Kaavya
Jayaramayya, Mahalaxmi Iyer Volume 725, 10 July 2020, 138277
https://www.sciencedirect.com/science/article/pii/S0048969720317903

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Final exam english ii reynaldi 20160700011

  • 1. Final Exam English II International Spread of The COVID-19 Outbreak REYNALDI 20160700011 STUDY PROGRAM INFORMATION SYSTEMS FACULTY OF SCIENCE AND TECHNOLOGY
  • 2. UNIVERSITAS BUDDHI DHARMA Beginning in December 2019, Chinese health authorities have been closely monitoring a cluster of pneumonia cases in the city of Wuhan in Hubei province, China. The pathogen that causes the viral pneumonia in affected individuals is the newly recognized coronavirus known as severe acute respiratory syndrome–coronavirus 2 (SARS-CoV-2) (WHO, 2020). Early reports predicted the onset of a potential Coronavirus outbreak given the estimate of a reproduction number for the 2019 Novel (New) Coronavirus (COVID-19, named by WHO on Feb 11, 2020) which was deemed to be significantly larger than 1 (ranges from 2.24 to 3.58) (S. Zhao, etc 2020). As of January 30, 2020, 7734 cases have been confirmed in China and 90 other cases have also been reported from a number of countries that include Taiwan, Thailand, Vietnam, Malaysia, Nepal, Sri Lanka, Cambodia, Japan, Singapore, Republic of Korea, United Arab Emirates, United States, The Philippines, India, Australia, Canada, Finland, France, and Germany. The case fatality rate was calculated to be 2.2% (170/7824) (M. Bassetti, etc 2020). Patients infected with COVID-19 showed higher leukocyte numbers, abnormal respiratory findings, and increased levels of plasma pro-inflammatory cytokines. One of the COVID-19 case reports showed a patient at 5 days of fever presented with a cough, coarse breathing sounds of both lungs, and a body temperature of 39.0 °C. The patient's sputum showed positive real- time polymerase chain reaction results that confirmed COVID-19 infection (J. Lei, etc 2020). Based on the large number of infected people that were exposed to the wet animal market in Wuhan City where live animals are routinely sold, it is suggested that this is the likely zoonotic origin of the COVID-19. Efforts have been made to search for a reservoir host or intermediate carriers from which the infection may have spread to humans. Initial reports identified two species of snakes that could be a possible reservoir of the COVID-19. However, to date, there has been no consistent evidence of coronavirus reservoirs other than mammals and birds (M. Bassetti, 2020 & W. Ji, 2020). Starting in early February 2020, 59 airline companies suspended or limited flights to mainland China, and several countries—including the United States, Russia, Australia, and Italy—have imposed government-issued travel restrictions (New York Times, 2020). this is done to prevent the spread of the virus from becoming more widespread.
  • 3. The experts have done several analyzes and the analysis of the COVID-19 outbreak and the modeling assessment of the effects of travel limitations could be beneficial to national and international agencies for public health response planning. We show that, by January 23, 2020, the epidemic has already spread to other cities within mainland China. The travel quarantine around Wuhan has only modestly delayed the spread of disease to other areas of mainland China. This finding is consistent with the results of separate studies on the diffusion of SARS- CoV-2 in mainland China (H. Tian, etc, 2020). The person-to-person transmission of COVID-19 infection led to the isolation of patients that were administered a variety of treatments. At present, there are no specific antiviral drugs or vaccine against COVID-19 infection for potential therapy of humans. The only option available is using broad-spectrum antiviral drugs like Nucleoside analogues and also HIV-protease inhibitors that could attenuate virus infection until the specific antiviral becomes available (H. Lu Drug, 2020). With 3405 deaths from covid-19, Italy’s fatalities now exceed those of China. There were 427 deaths in the 24 hours until 6 pm on 19 March, according to Italy’s civil protection chief Angelo Borrelli. China’s death toll is 3245. Two doctors died from the covid-19 in Como on 19 March, according to the federation of Italian doctors’ guilds. They were respiratory specialist Giuseppe Lanati and family doctor Luigi Frusciante, both of whom had come out of retirement to work during the emergency. There have now been 13 deaths among Italian doctors, the federation said. (Day, Michael, 2020). Extensive measures to reduce person-to-person transmission of COVID-19 are required to control the current outbreak. Special attention and efforts to protect or reduce transmission should be applied to susceptible populations including children, health care providers, and elderly people. A guideline was published for the medical staff, healthcare providers, and, public health individuals and researchers who are interested in the 2019-nCoV (Y.H. Jin, L, etc, 2020).Also it has been reported that some of the Asian populations are more susceptible to acquire this COVID-19 infection when compared to the other races populations (Xu, 2020). Following are the protective measures given by WHO (2020d), 1. Wash hands completely using an alcohol-based hand sanitizer will kill the virus, 2. Avoid touching eyes, nose and mouth when outside. 3. Be updated about the virus.
  • 4. 4. Avoid travelling or gathering in crowded places. 5. Women with infants are encouraged to breastfeed their babies to enhance their immunity. WHO is coordinating efforts to develop vaccines and medicines to prevent and treat COVID-19 (WHO, 2020d). National Institutes of Health (NIH), has mentioned that SARS- CoV-2 could survive for up to 3 h maximum as aerosols to a maximum of three days on surfaces. Slowing the spread of the COVID-19 cases will significantly reduce the strain on the healthcare system of the country by limiting the number of people who are severely sick by COVID-19 and need hospital care. It will also give researchers more time to develop the vaccine against COVID-19. So, it's time for all the citizens to join hands together to fight against coronavirus by practicing self-hygiene and social distancing (Balachandar Vellingir, etc, 2020). It is hoped that with our health and hygiene we will be able to release us from the COVID-19 virus and a vaccine for this virus can be found soon, and we can return to our daily lives without fearing overshadowed by this virus.
  • 5. REFERENCES World Health Organization (WHO), “Novel Coronavirus – China” (WHO, 2020); www.who.int/csr/don/12-january-2020-novel-coronavirus-china/en/. S. Zhao, Q. Lin, J. Ran, S.S. Musa, G. Yang, W. Wang, et al. Preliminary estimation of the basic reproduction number of novel coronavirus (2019-nCoV) in China, from 2019 to 2020: a data-driven analysis in the early phase of the outbreak. 92 (2020), pp. 214-217, https://doi.org /10.1016/j.ijid.2020.01.050 M. Bassetti, A. Vena, D. Roberto Giacobbe The Novel Chinese Coronavirus (2019-nCoV) Infections: challenges for fighting the storm Eur. J. Clin. Invest. (2020), Article e13209, https://doi.org /10.1111/eci.13209 J. Lei, J. Li, X. Li, X. Qi CT imaging of the 2019 novel coronavirus (2019-nCoV) pneumonia Radiology (2020), p. 200236, https://doi.org/10.1148/radiol.2020200236 M. Bassetti, A. Vena, D. Roberto Giacobbe The Novel Chinese Coronavirus (2019-nCoV) Infections: challenges for fighting the storm Eur. J. Clin. Invest. (2020), Article e13209, https://doi.org /10.1111/eci.13209 W. Ji, W. Wang, X. Zhao, J. Zai, X. Li Homologous recombination within the spike glycoprotein of the newly identified coronavirus may boost cross-species transmission from snake to human J. Med. Virol., 92 (4) (2020), pp. 433-440, https://doi.org/10.1002/jmv.25682 New York Times, “North Korea Bans Foreign Tourists Over Coronavirus, Tour Operator Says” (2020); https://www.nytimes.com/2020/01/21/world/asia/coronavirus-china-north-korea- tourism-ban.html H. Tian, Y. Liu, Y. Li, C.-H. Wu, B. Chen, M. U. G. Kraemer, B. Li, J. Cai, B. Xu, Q. Yang, B. Wang, P. Yang, Y. Cui, Y. Song, P. Zheng, Q. Wang, O. N. Bjornstad, R. Yang, B. Grenfell, O. Pybus, C. Dye, The impact of transmission control measures during the first 50 days of the COVID-19 epidemic in China. medRxiv https://doi.org/2020.01.30.20019844 [Preprint]. 10 March 2020. https://doi.org/10.1101/2020.01.30.20019844 H. Lu Drug treatment options for the 2019-new coronavirus (2019-nCoV) Biosci. Trends (2020), https://doi.org/10.5582/bst.2020.01020 Day, Michael.BMJ : British Medical Journal (Online); London Vol. 368, (Mar 23, 2020). https://doi.org/10.1136/bmj.m1165
  • 6. Y.H. Jin, L. Cai, Z.S. Cheng, H. Cheng, T. Deng, Y.P. Fan, et al. A rapid advice guideline for the diagnosis and treatment of 2019 novel coronavirus (2019-nCoV) infected pneumonia (standard version) Mil. Med. Res., 7 (2020), p. 4 Y. Xu Unveiling the origin and transmission of 2019-nCoV Trends Microbiol., 28 (2020), pp. 239-240, https://doi.org/10.1016/j.tim.2020.02.001 World Health Organization (WHO) Surveillance case definitions for human infection with novel coronavirus (nCoV) (2020) https://apps.who.int/iris/handle/10665/330376 COVID-19: A promising cure for the global panic Balachandar Vellingir, Kaavya Jayaramayya, Mahalaxmi Iyer Volume 725, 10 July 2020, 138277 https://www.sciencedirect.com/science/article/pii/S0048969720317903