The document details the emergence and spread of COVID-19, beginning with early warnings from doctors in Wuhan and the identification of the novel coronavirus as the pathogen responsible for pneumonia cases. It highlights the initial reactions from Chinese authorities, the virus's relationship to previous coronaviruses, and the timeline of its spread across China and to other countries. Further, it discusses the symptoms, potential animal hosts, transmissibility, and the importance of preventative measures, including social distancing and personal hygiene.

1. background
"2003 Greater China of severe acute respiratory syndrome, it left casualties from SARS were patients
with 7 showing symptoms similar had occurred" that the gain to the hospital documents China Wuhan
City center hospital doctor Lee wonryang was concerned about the possibility of the infection
spreading, 2019 On December 30th, with seven fellow doctors , they tried to inform and spread the risk
situation through social media (SNS). However, after receiving a notification from the Chinese
authorities that "spreading false information and making public sentiment uneasy." "If you continue to
circulate related facts, you may be arrested." I wrote and signed an autograph acknowledging that.
Chinese
Must Know
Each&Everything
COVID-19

2. background
"2003 Greater China of severe acute respiratory syndrome, it left casualties from SARS were patients
with 7 showing symptoms similar had occurred" that the gain to the hospital documents China Wuhan
City center hospital doctor Lee wonryang was concerned about the possibility of the infection
spreading, 2019 On December 30th, with seven fellow doctors , they tried to inform and spread the risk
situation through social media (SNS). However, after receiving a notification from the Chinese
authorities that "spreading false information and making public sentiment uneasy." "If you continue to
circulate related facts, you may be arrested." I wrote and signed an autograph acknowledging that.
Chinese
You Must Know
Each&Everything
COVID-19

3. On January 7, 2020, CCTV revealed that the pathogen causing pneumonia of unknown cause in Wuhan is a new class of coronavirus. [2] [3]
The complete sequence of this virus was identified by the Shanghai Public Health and Medical Clinical Center, Wuhan Central Clinic,
Huazhong University of Science and Technology, Wuhan City Disease Prevention and Mutual Aid Center.武漢市疾病予防控制中心) ,
University of Sydney is decrypted by the cooperation of the University of Sydney, including Edward. It was released on Virological.org on
January 11, 2020 by Professor Chang Yong-Jeon of the Shanghai Public Health Clinical Center under the cooperation of Professor C.
Holmes. [4] [5] On the 14th, it was officially published in Genbank , an international nucleic acid sequence database . [6] University of Hong
Kong Department of Microbiology and Infectious Diseases Major Win gwokyung According to a report of a professor, a comparison with
other kinds of viruses and corona viruses, China Zhejiang Zhoushan found in the bat SARS virus and the closest, bat SARS Viruses, human
SARS virus, and musk cat SARS virus are also close to 80%. [7]
It’s A Pandamic

4. s considered the birthplace virus Angry Fish Market (Wuhan market) is the name fishery market or in practice, and also processing
and trading a variety of wildlife, bamboo rats and badgers like wild animals is known to contain infectious agents likely to be even
higher. [8]
deployment
Of the first 41 confirmed cases of 2019-nCoV infection, two-thirds were found to be related to the Wuhan Huanan Seafood
Wholesale Market , which sold live animals . [43] [44] [45] [46]
The virus spread to other Chinese provinces through the Chinese New Year in early and mid-January 2020. On January 20,
China reported a sharp increase in about 140 new patients, including two in Beijing and one in Shenzhen . [47]
Dead
The first death outside China was the Philippines . [48] In the Philippines , a 44-year-old Chinese man from Wuhan , China , with
coronavirus developed severe pneumonia and died on February 1. [49] Since then, deaths have occurred around the world. According to
the National Health Commission of China, the majority of those who died were elderly patients, about 80% of those who died were
among those over the age of 60, and 75%

5. had diseases including cardiovascular disease and diabetes . [50]
The body of this part of the corona virus infection -19 § signs and symptoms are.
Infected people may be asymptomatic or may have mild to severe symptoms such as fever, dry cough, shortness of breath,
diarrhea, and sore throat. In addition, asymptomatic is not completely asymptomatic, rather than a weak immune function
should be seen. [51] [52]

6. cause
VIRUS
Main article: Swine coronavirus 2019 is.
It has been suggested that bats and snakes are the most likely causes of the virus . According to the science information portal ``EurekaAlert''
on the 23rd, medical staff from Beijing University, Guangxi University, and Ningbo University in China are the host of the novel coronavirus
SARS-Cov-2, a new type of pneumonia of unknown cause that has spread in Wuhan. He published a paper in the international journal The
Journal of Virology (JMV). According to the paper, "The results from the evolutionary chemical analysis (tracking the virus transformation
process) show that the snake is a wild animal pathogen of SARS-Cov-2. ) Is the most likely.” The research team also revealed through RNA
genome sequencing that SARS-Cov-2 is a recombinant virus between the bat coronavirus and the coronavirus of unknown origin. According to
the team, this recombination process took place in a viral spike glycoprotein that recognizes cell surface receptors. In addition, lead author
Professor Wei Ji said, "Homologous recombination within the spike glycoprotein suggests that it may contribute to cross-species infection of
SARS-Cov-2 from snake to human." Revealed. [53] [54]V

7. Detailed genomic analysis results for the novel coronavirus (COVID-19) were first released on January 23, 2020. On this day, a
research paper centered on the Wuhan Institute of Virology under the Chinese Academy of Sciences, a research paper that stated that
this virus is the same species as the SARS virus (SARS, severe acute respiratory syndrome), which was pandemic in 2003, and is
almost identical to the coronavirus found in bats. Was published in bioRxiv, an online publication in the field of biology. In the paper,
the researchers analyzed the entire genome sequence of the virus collected from five patients in the early stages of spread, and found
that it was 79.5% consistent with the SARS coronavirus and 96% with the coronavirus found in bats. When infected with this virus,
symptoms such as high fever, dry cough, headache, shortness of breath, and pneumonia occur. Although the mortality rate is not high,
respiratory failure caused by alveolar damage can lead to death in severe cases. The researchers also revealed that the coronavirus'
receptor, which penetrated human lung cells, was identical to the SARS virus. Based on this, the researchers said it is worth testing
whether SARS treatment can also be used in patients with new pneumonia. Earlier, another Chinese researcher published a paper in
the international journal, "The Journal of Medical Virology," suggesting that the virus may have made snakes an intermediate host.
However, the'MIT Technology Review' countered that this appears to be an error. [55]

8. Infectious
Li Gang (李剛), director of the Wuhan Disease Control Center, said in a CCTV interview in China , "The
contagiousness of the novel coronavirus is not strong." The World Health Organization also said that the contagious
nature of the new pneumonia outbreak in Wuhan, Hubei Province, China, is not as strong as there have been no cases
of human infection. However, after this announcement, there have been a huge number of cases of infection between
humans. Hong Kong's South China Morning Post (SCMP) said that the first patient outside Greater China, a Thai
pneumonia patient, was infected even though he did not visit the Wuhan market, the epicenter of the new pneumonia
spread from Wuhan . Reported on January 15th. It is estimated that the contagiousness of the novel coronavirus is
stronger than MERS and weaker than SARS. [56]

9. The spread of infectious diseases is divided into four stages.
● Stage 1: Transmitted from animal to human due to virus mutation
● Stage 2: Human liver transmission
● Step 3: Infect the patient's family or health care staff
● Stage 4: large outbreaks in the community
On January 21, 2020, Professor Yun Gueng Yong of Hong Kong University remarked on the South China Morning Post that the spread of the
epidemic has entered the third stage. [57] [58]
On January 23, 2020, a Chinese doctor who suffered from the pneumonia in the course of treatment of a new type of pneumonia that spread in
Wuhan (SARS, severe acute respiratory syndrome) study said that it appeared to be infected with the novel coronavirus through the cornea. . [59]
The number of basal infectious reproductive products (R0) is a number that indicates how many people a patient directly transmits an infectious
disease to. If the R0 value is 2, it means that one patient transmits the infectious disease directly to two people. [60]
On January 23, the World Health Organization (WHO) estimated the number of basic infectious reproductive products (R0) to be 1.4-2.5 in
relation to the transmission of the novel coronavirus . [61] The level is similar to the flu ( influenza ) (2 to 3 people). However, some other papers
have analyzed that the R0 value is 4. On January 25, a research team at the MRC World Infectious Disease Analysis Center at Imperial College
London in England analyzed that an average of about 2.6 patients with new pneumonia (R0 value 2.1 to 3.5) infects. [62]

10. Hong Kong University Professor Yun Gong Yong suggested the possibility that a new type of pneumonia that spread in Wuhan would
enter the same full-scale spread phase as in the 2003 SARS era . Professor Yun was particularly concerned about the possibility that
a super-propagator had already occurred , with a deadly virus in contact with a large crowd . [57] [58]
Was involved in the SARS response, China prominent scientists play a leading role in the new pneumococcal corresponding spread in
this Wuhan, South Central China mountains (鐘南山) is also "a key concern of swine pneumonia diffusion preventing proliferation in
Wuhan Super preacher said, would prevent the emergence of" " To this end, it is an urgent need to prevent people with symptoms of
new pneumonia from leaving Wuhan.” At the time of the SARS pandemic, the super preacher was called the'Poison King', and he
explained that there were cases where one person infected over 100 people. [63]
A superspreader or super spreader is a host that infects particularly more secondary contacts than other individuals infected with the
same virus or bacteria. When the SARS outbreak in Beijing, China in 2003, epidemiologists defined an individual who transmitted
SARS to at least eight people as a super-propagator. [64]

11. Diagnosis
Main article: -19 diagnose coronavirus infection is.
The World Health Organization has published several test protocols for SARS-CoV-2 . [65] [66] Real-time PCR testing
is used. [67] Respiratory or blood samples can be diagnosed. [68] Results generally come within hours to days. [69] [70]

12. prevention
Personal hygiene to prevent the spread of disease includes washing your hands, not touching your eyes, nose and mouth with
unwashed hands, and wearing a mask in public places. [71] [72] [73] Social or lifestyle distancing is also recommended to prevent
transmission . [74] [75]
Governments in many countries recommend refraining from unnecessary travel to countries and regions with cases of infection. [76]
China has banned the trade and consumption of wild animals. [77] In general, coronavirus has a shorter survival time in a hot and humid
environment than in a cold, dry environment, and direct data related to this and temperature reference information related to virus
inactivation are still insufficient. [78]
Contact follow-up is an important way for health authorities to determine the cause of infection and to prevent further transmission.

13. Washing hands
Main article: Hand washing is.
Hand washing is recommended to prevent the spread of the disease . The Centers for Disease Control and Prevention
(CDC) recommends that people wash their hands frequently with soap and water for at least 20 seconds, especially
after going to the bathroom or if their hands are dirty. If soap and water are not readily available, an alcohol-based
hand sanitizer with at least 60% alcohol by volume is recommended. [71] The World Health Organization also advises
people not to touch their eyes, nose and mouth with unwashed hands. [

14. Respiratory hygiene
Health agencies recommend covering your mouth and nose with a bent elbow or a tissue or a mask when coughing or
sneezing. If you cough or sneeze with a tissue, it should be discarded immediately. [72] [81]
It is recommended to wear a mask because it can be infected with droplets (spit) that disperse when talking,
sneezing and coughing . [82]

15. Social distancing
Social distancing can slow the spread of diseases by minimizing close contact between individuals. Public places such as
schools, companies, stadiums, theaters, shopping malls, etc. are sometimes closed, and people stay at home, limit travel,
avoid crowded areas, do not shake hands, and physically distance themselves from others to establish social distancing. can
do. [83] [84] [85]
It is also recommended to refrain from visiting hospitals or medical institutions for non-treatment purposes.
Self-isolation
People diagnosed with coronavirus infection-19 and those suspected of being infected are encouraged to self-isolate at
home.