Fifth Normal Form (5NF) is a state where a relation is decomposed into independent subrelations such that joining them back together does not lose or create any new data. To be in 5NF, a relation must be in 4NF and cannot be further decomposed without violating lossless join or introducing redundancy. A join dependency exists when a relation can be recreated by joining its decomposed subrelations based on their candidate keys. Being free of join dependencies means a relation is in 5NF.