SlideShare a Scribd company logo
Kristin Schneeman Program Director September 12, 2008 “ What You Seed Is What You Get”  Making Faster Cures  the Central Organizing Principle  of the Research Enterprise
Saving lives by saving time Our mission is to identify and implement global solutions to accelerate the pace of  discovery and clinical development of new therapies  for the treatment of disease.
FasterCures’  Blueprint for Change Research Leadership and Innovation The Redstone Acceleration and Innovation Network (TRAIN):   Sharing best practices in funding and conducting innovative research Philanthropy Advisory Service:   Develop a more transparent information marketplace to help philanthropists make informed investment decisions TRAIN-dustrial Relations:   Facilitate partnerships between nonprofits and industry to help translate research into therapeutic breakthroughs
FasterCures’  Blueprint for Change Research Tools and Resources Patients Helping Doctors BioBank Central Electronic health records Research Environment Advocacy for change at the FDA and NIH Intellectual property and technology transfer HIPAA reform
“Entrepreneurs for Cures” What would your business model be if your bottom line were curing a disease?
The High Costs of Business as Usual We’re spending a lot on treating disease: $2.1 trillion on healthcare in 2006 – more than $7000 per person We’re not spending much on curing disease: And productivity is falling: Sources: CMS, Research!America
A New Central Organizing Principle Our current research infrastructure has led to great advances  in knowledge of human health and disease;  but it is  not  a good system for developing therapies for patients  studying biology curing diseases
The Translation Gap Basic research  is the earliest stage of research, carried out for the advancement of knowledge, without necessarily any regard to its application to practical problems. Translational research  is the process of applying ideas, insights, and discoveries generated through basic scientific inquiry to the treatment and prevention of human disease – the critical bridge between basic research and clinical research. Clinical research  is research in human subjects aiming toward approved treatments for patients.
Separating what we  need to do in science and what we need to do in the culture of science to accelerate curing diseases
TRAIN: You Are Not Alone The Redstone Acceleration and Innovation Network Collaborative, mission-driven, results-oriented, and strategic in their use of capital, these groups are motivated solely by moving promising therapies from the laboratory bench to the patient’s bedside as rapidly as possible – even those that do not directly fund therapy development.
“ Venture Philanthropy”  -> “Passion Capital” Strategic use of capital Building collaborations Streamlining the grantmaking process Sharing information “… patient groups with an entrepreneurial bent have become the drug industry’s new power brokers.”   -  Forbes , 9/15/08
Nonprofits as “De-Riskers” Developing pre-clinical tools Targeting research to support translation Funding mechanisms that bring in industry Managing academic science Access to patient community New indications for existing drugs High-throughput screening of promising compounds Access to scientific expertise Advocating with FDA
New Business Models to Accelerate Research More than $66 million in research funding since 2005 Actively supports more than 30 new treatments in development – 4 FDA-approved Partners include Vertex Pharmaceuticals, Parion Sciences, PTC Therapeutics, Inspire Pharmaceuticals, Gilead Sciences, Altus Pharmaceuticals Research  Preclinical  Phase 1  Phase 2  Phase 3  To Patients
New Business Models to Accelerate Research Funded $126 million in research to date, two-thirds for translational research Funded testing of over 100 therapeutic targets for Parkinson’s Disease Partnership with Elan Corp. gives Elan first look at promising projects
New Business Models to Accelerate Research Has raised $102 million to fund 70 labs worldwide 4 new treatments approved in 4 years 10 clinical trials facilitated by MMRF’s Research Consortium 30 MMRF-funded compounds now in preclinical studies and clinical trials
Instead of  following the money,  lead the money.

More Related Content

What's hot

A Vision for a National Research Network
A Vision for a National Research Network A Vision for a National Research Network
A Vision for a National Research Network
Brian Ahier
 
Providing actionable healthcare analytics at scale: Insights from the Nationa...
Providing actionable healthcare analytics at scale: Insights from the Nationa...Providing actionable healthcare analytics at scale: Insights from the Nationa...
Providing actionable healthcare analytics at scale: Insights from the Nationa...
Nuffield Trust
 
Week 12 assignment
Week 12 assignmentWeek 12 assignment
Week 12 assignment
lucianqueen1983
 
Achieving Outcomes for NZ using Health IT
Achieving Outcomes for NZ using Health IT Achieving Outcomes for NZ using Health IT
Achieving Outcomes for NZ using Health IT
Health Informatics New Zealand
 
Radiology Cost Effectiveness - By Jeffrey Shyu
Radiology Cost Effectiveness - By Jeffrey ShyuRadiology Cost Effectiveness - By Jeffrey Shyu
Radiology Cost Effectiveness - By Jeffrey Shyu
Brigham and Women's Hospital
 
Cost Effectiveness in Radiology - By Jeffrey Shyu
Cost Effectiveness in Radiology - By Jeffrey ShyuCost Effectiveness in Radiology - By Jeffrey Shyu
Cost Effectiveness in Radiology - By Jeffrey Shyu
Brigham and Women's Hospital
 
Sharing and standards christopher hart - clinical innovation and partnering...
Sharing and standards   christopher hart - clinical innovation and partnering...Sharing and standards   christopher hart - clinical innovation and partnering...
Sharing and standards christopher hart - clinical innovation and partnering...
Christopher Hart
 
Sally Redman | Early findings from SPIRIT
Sally Redman | Early findings from SPIRITSally Redman | Early findings from SPIRIT
Sally Redman | Early findings from SPIRIT
Sax Institute
 
How should we value HRQoL in children?
How should we value HRQoL in children?How should we value HRQoL in children?
How should we value HRQoL in children?
Office of Health Economics
 
2016 Scope david cocker
2016 Scope david cocker2016 Scope david cocker
2016 Scope david cocker
David Cocker
 
What is international collaborative research?
What is international collaborative research?What is international collaborative research?
What is international collaborative research?
Dr Edward Fitzgerald
 
Prof Trevor Duffy, Chief Academic Officer, RCSI Hospitals Group
Prof Trevor Duffy,  Chief Academic Officer, RCSI Hospitals GroupProf Trevor Duffy,  Chief Academic Officer, RCSI Hospitals Group
Prof Trevor Duffy, Chief Academic Officer, RCSI Hospitals Group
Investnet
 
Outcomes research power point for research class
Outcomes research power point for research classOutcomes research power point for research class
Outcomes research power point for research class
fochoa10
 
NCRIS and the health domain
NCRIS and the health domainNCRIS and the health domain
NCRIS and the health domain
ARDC
 
Chris Packham: Commissioning challenges
Chris Packham: Commissioning challengesChris Packham: Commissioning challenges
Chris Packham: Commissioning challenges
Nuffield Trust
 
Powering Medical Research With Data: The Research Analytics Adoption Model
Powering Medical Research With Data: The Research Analytics Adoption ModelPowering Medical Research With Data: The Research Analytics Adoption Model
Powering Medical Research With Data: The Research Analytics Adoption Model
Health Catalyst
 
Clinical trials data sharing
Clinical trials data sharingClinical trials data sharing
Clinical trials data sharing
ARDC
 
Mc dougall
Mc dougallMc dougall
Seamless Journey from Population Health to Precision Medicine
Seamless Journey from Population Health to Precision MedicineSeamless Journey from Population Health to Precision Medicine
Seamless Journey from Population Health to Precision Medicine
Orion Health
 
Investigator-initiated clinical trials: a community perspective
Investigator-initiated clinical trials: a community perspectiveInvestigator-initiated clinical trials: a community perspective
Investigator-initiated clinical trials: a community perspective
ARDC
 

What's hot (20)

A Vision for a National Research Network
A Vision for a National Research Network A Vision for a National Research Network
A Vision for a National Research Network
 
Providing actionable healthcare analytics at scale: Insights from the Nationa...
Providing actionable healthcare analytics at scale: Insights from the Nationa...Providing actionable healthcare analytics at scale: Insights from the Nationa...
Providing actionable healthcare analytics at scale: Insights from the Nationa...
 
Week 12 assignment
Week 12 assignmentWeek 12 assignment
Week 12 assignment
 
Achieving Outcomes for NZ using Health IT
Achieving Outcomes for NZ using Health IT Achieving Outcomes for NZ using Health IT
Achieving Outcomes for NZ using Health IT
 
Radiology Cost Effectiveness - By Jeffrey Shyu
Radiology Cost Effectiveness - By Jeffrey ShyuRadiology Cost Effectiveness - By Jeffrey Shyu
Radiology Cost Effectiveness - By Jeffrey Shyu
 
Cost Effectiveness in Radiology - By Jeffrey Shyu
Cost Effectiveness in Radiology - By Jeffrey ShyuCost Effectiveness in Radiology - By Jeffrey Shyu
Cost Effectiveness in Radiology - By Jeffrey Shyu
 
Sharing and standards christopher hart - clinical innovation and partnering...
Sharing and standards   christopher hart - clinical innovation and partnering...Sharing and standards   christopher hart - clinical innovation and partnering...
Sharing and standards christopher hart - clinical innovation and partnering...
 
Sally Redman | Early findings from SPIRIT
Sally Redman | Early findings from SPIRITSally Redman | Early findings from SPIRIT
Sally Redman | Early findings from SPIRIT
 
How should we value HRQoL in children?
How should we value HRQoL in children?How should we value HRQoL in children?
How should we value HRQoL in children?
 
2016 Scope david cocker
2016 Scope david cocker2016 Scope david cocker
2016 Scope david cocker
 
What is international collaborative research?
What is international collaborative research?What is international collaborative research?
What is international collaborative research?
 
Prof Trevor Duffy, Chief Academic Officer, RCSI Hospitals Group
Prof Trevor Duffy,  Chief Academic Officer, RCSI Hospitals GroupProf Trevor Duffy,  Chief Academic Officer, RCSI Hospitals Group
Prof Trevor Duffy, Chief Academic Officer, RCSI Hospitals Group
 
Outcomes research power point for research class
Outcomes research power point for research classOutcomes research power point for research class
Outcomes research power point for research class
 
NCRIS and the health domain
NCRIS and the health domainNCRIS and the health domain
NCRIS and the health domain
 
Chris Packham: Commissioning challenges
Chris Packham: Commissioning challengesChris Packham: Commissioning challenges
Chris Packham: Commissioning challenges
 
Powering Medical Research With Data: The Research Analytics Adoption Model
Powering Medical Research With Data: The Research Analytics Adoption ModelPowering Medical Research With Data: The Research Analytics Adoption Model
Powering Medical Research With Data: The Research Analytics Adoption Model
 
Clinical trials data sharing
Clinical trials data sharingClinical trials data sharing
Clinical trials data sharing
 
Mc dougall
Mc dougallMc dougall
Mc dougall
 
Seamless Journey from Population Health to Precision Medicine
Seamless Journey from Population Health to Precision MedicineSeamless Journey from Population Health to Precision Medicine
Seamless Journey from Population Health to Precision Medicine
 
Investigator-initiated clinical trials: a community perspective
Investigator-initiated clinical trials: a community perspectiveInvestigator-initiated clinical trials: a community perspective
Investigator-initiated clinical trials: a community perspective
 

Similar to FasterCures Presentation at LifeFest 2008

FasterCures Presentation: Fostering innovation while delivering treatments an...
FasterCures Presentation: Fostering innovation while delivering treatments an...FasterCures Presentation: Fostering innovation while delivering treatments an...
FasterCures Presentation: Fostering innovation while delivering treatments an...
TRAIN Central Station
 
From personalized medicine to personalized science - a new concept in biogero...
From personalized medicine to personalized science - a new concept in biogero...From personalized medicine to personalized science - a new concept in biogero...
From personalized medicine to personalized science - a new concept in biogero...
Anna Ericsson
 
The Clinical and Translational Science Awards (CTSA) Program: What can it do ...
The Clinical and Translational Science Awards (CTSA) Program: What can it do ...The Clinical and Translational Science Awards (CTSA) Program: What can it do ...
The Clinical and Translational Science Awards (CTSA) Program: What can it do ...
CTSciNet .org
 
Translational researchfinal4whsla
Translational researchfinal4whslaTranslational researchfinal4whsla
Translational researchfinal4whsla
Allan Barclay
 
Canadian Institute of Health Research
Canadian Institute of Health ResearchCanadian Institute of Health Research
Canadian Institute of Health Research
Jennifer Hindorff
 
Engaging Patients in Research and Tool Development
Engaging Patients in Research and Tool DevelopmentEngaging Patients in Research and Tool Development
Engaging Patients in Research and Tool Development
Patient-Centered Outcomes Research Institute
 
US Precision Medicine Initiative
US Precision Medicine InitiativeUS Precision Medicine Initiative
US Precision Medicine Initiative
Dr Dev Kambhampati
 
Latest Project to Cure PKD
Latest Project to Cure PKDLatest Project to Cure PKD
Latest Project to Cure PKD
Sean Flaherty
 
Comparative Effectiveness Research
Comparative Effectiveness ResearchComparative Effectiveness Research
Comparative Effectiveness Research
Rick Mathis
 
Knowledge transfer, and evidence informed health policy-minster's meeting
Knowledge transfer, and evidence informed health policy-minster's meetingKnowledge transfer, and evidence informed health policy-minster's meeting
Knowledge transfer, and evidence informed health policy-minster's meeting
Dr Ghaiath Hussein
 
Translational medicine
Translational medicineTranslational medicine
Translational medicine
Haroon Rashid
 
The Patient-Centered Clinical Trial: A New Paradigm
The Patient-Centered Clinical Trial: A New ParadigmThe Patient-Centered Clinical Trial: A New Paradigm
The Patient-Centered Clinical Trial: A New Paradigm
John Reites
 
Move Your Research Out of the Ivory Tower and Impact Health: Translating Earl...
Move Your Research Out of the Ivory Tower and Impact Health: Translating Earl...Move Your Research Out of the Ivory Tower and Impact Health: Translating Earl...
Move Your Research Out of the Ivory Tower and Impact Health: Translating Earl...
CTSI at UCSF
 
THE LARGE DATA DEMO - ONE MODEL
THE LARGE DATA DEMO - ONE MODELTHE LARGE DATA DEMO - ONE MODEL
THE LARGE DATA DEMO - ONE MODEL
Stephen Allan Weitzman
 
Crowd funding in a clinical research
Crowd funding in a clinical researchCrowd funding in a clinical research
Crowd funding in a clinical research
sushant deshmukh
 
P4 Medicine May 2011
P4 Medicine May 2011P4 Medicine May 2011
CMT update 2014 fall
CMT update 2014 fallCMT update 2014 fall
CMT update 2014 fall
Sean Ekins
 
Nhp Conference Feb 2004
Nhp Conference Feb 2004Nhp Conference Feb 2004
Nhp Conference Feb 2004
pierrecharest
 
Testing times for clinical trials - Perscetives on personalised health care
Testing times for clinical trials - Perscetives on personalised health careTesting times for clinical trials - Perscetives on personalised health care
Testing times for clinical trials - Perscetives on personalised health care
Mats Sundgren
 
TransCelerate Overview - Clinical Research Access & Information Exchange Ini...
TransCelerate Overview -  Clinical Research Access & Information Exchange Ini...TransCelerate Overview -  Clinical Research Access & Information Exchange Ini...
TransCelerate Overview - Clinical Research Access & Information Exchange Ini...
TransCelerate
 

Similar to FasterCures Presentation at LifeFest 2008 (20)

FasterCures Presentation: Fostering innovation while delivering treatments an...
FasterCures Presentation: Fostering innovation while delivering treatments an...FasterCures Presentation: Fostering innovation while delivering treatments an...
FasterCures Presentation: Fostering innovation while delivering treatments an...
 
From personalized medicine to personalized science - a new concept in biogero...
From personalized medicine to personalized science - a new concept in biogero...From personalized medicine to personalized science - a new concept in biogero...
From personalized medicine to personalized science - a new concept in biogero...
 
The Clinical and Translational Science Awards (CTSA) Program: What can it do ...
The Clinical and Translational Science Awards (CTSA) Program: What can it do ...The Clinical and Translational Science Awards (CTSA) Program: What can it do ...
The Clinical and Translational Science Awards (CTSA) Program: What can it do ...
 
Translational researchfinal4whsla
Translational researchfinal4whslaTranslational researchfinal4whsla
Translational researchfinal4whsla
 
Canadian Institute of Health Research
Canadian Institute of Health ResearchCanadian Institute of Health Research
Canadian Institute of Health Research
 
Engaging Patients in Research and Tool Development
Engaging Patients in Research and Tool DevelopmentEngaging Patients in Research and Tool Development
Engaging Patients in Research and Tool Development
 
US Precision Medicine Initiative
US Precision Medicine InitiativeUS Precision Medicine Initiative
US Precision Medicine Initiative
 
Latest Project to Cure PKD
Latest Project to Cure PKDLatest Project to Cure PKD
Latest Project to Cure PKD
 
Comparative Effectiveness Research
Comparative Effectiveness ResearchComparative Effectiveness Research
Comparative Effectiveness Research
 
Knowledge transfer, and evidence informed health policy-minster's meeting
Knowledge transfer, and evidence informed health policy-minster's meetingKnowledge transfer, and evidence informed health policy-minster's meeting
Knowledge transfer, and evidence informed health policy-minster's meeting
 
Translational medicine
Translational medicineTranslational medicine
Translational medicine
 
The Patient-Centered Clinical Trial: A New Paradigm
The Patient-Centered Clinical Trial: A New ParadigmThe Patient-Centered Clinical Trial: A New Paradigm
The Patient-Centered Clinical Trial: A New Paradigm
 
Move Your Research Out of the Ivory Tower and Impact Health: Translating Earl...
Move Your Research Out of the Ivory Tower and Impact Health: Translating Earl...Move Your Research Out of the Ivory Tower and Impact Health: Translating Earl...
Move Your Research Out of the Ivory Tower and Impact Health: Translating Earl...
 
THE LARGE DATA DEMO - ONE MODEL
THE LARGE DATA DEMO - ONE MODELTHE LARGE DATA DEMO - ONE MODEL
THE LARGE DATA DEMO - ONE MODEL
 
Crowd funding in a clinical research
Crowd funding in a clinical researchCrowd funding in a clinical research
Crowd funding in a clinical research
 
P4 Medicine May 2011
P4 Medicine May 2011P4 Medicine May 2011
P4 Medicine May 2011
 
CMT update 2014 fall
CMT update 2014 fallCMT update 2014 fall
CMT update 2014 fall
 
Nhp Conference Feb 2004
Nhp Conference Feb 2004Nhp Conference Feb 2004
Nhp Conference Feb 2004
 
Testing times for clinical trials - Perscetives on personalised health care
Testing times for clinical trials - Perscetives on personalised health careTesting times for clinical trials - Perscetives on personalised health care
Testing times for clinical trials - Perscetives on personalised health care
 
TransCelerate Overview - Clinical Research Access & Information Exchange Ini...
TransCelerate Overview -  Clinical Research Access & Information Exchange Ini...TransCelerate Overview -  Clinical Research Access & Information Exchange Ini...
TransCelerate Overview - Clinical Research Access & Information Exchange Ini...
 

More from TRAIN Central Station

Valley of Death CAN Briefing Slides
Valley of Death CAN Briefing SlidesValley of Death CAN Briefing Slides
Valley of Death CAN Briefing Slides
TRAIN Central Station
 
BIO 2010 Partnering with Patients
BIO 2010 Partnering with PatientsBIO 2010 Partnering with Patients
BIO 2010 Partnering with Patients
TRAIN Central Station
 
BIO 2010 Partnering with Patients
BIO 2010 Partnering with PatientsBIO 2010 Partnering with Patients
BIO 2010 Partnering with Patients
TRAIN Central Station
 
Pharma Assets Portal
Pharma Assets PortalPharma Assets Portal
Pharma Assets Portal
TRAIN Central Station
 
Valley of Death Panel Slides at the Partnering for Cures Conference, December...
Valley of Death Panel Slides at the Partnering for Cures Conference, December...Valley of Death Panel Slides at the Partnering for Cures Conference, December...
Valley of Death Panel Slides at the Partnering for Cures Conference, December...
TRAIN Central Station
 
Progeria Research Foundation at Partnering for Cures
Progeria Research Foundation at Partnering for CuresProgeria Research Foundation at Partnering for Cures
Progeria Research Foundation at Partnering for Cures
TRAIN Central Station
 
PATH Malaria Vaccine Initiative
PATH Malaria Vaccine InitiativePATH Malaria Vaccine Initiative
PATH Malaria Vaccine Initiative
TRAIN Central Station
 
Life Raft Group: A New Model for Cancer Research
Life Raft Group: A New Model for Cancer ResearchLife Raft Group: A New Model for Cancer Research
Life Raft Group: A New Model for Cancer Research
TRAIN Central Station
 
Leukemia Lymphoma Society: An Invitation to Innovation
Leukemia Lymphoma Society: An Invitation to InnovationLeukemia Lymphoma Society: An Invitation to Innovation
Leukemia Lymphoma Society: An Invitation to Innovation
TRAIN Central Station
 
Susan G. Komen for the Cure Presentation at Partnering for Cures
Susan G. Komen for the Cure Presentation at Partnering for CuresSusan G. Komen for the Cure Presentation at Partnering for Cures
Susan G. Komen for the Cure Presentation at Partnering for Cures
TRAIN Central Station
 
JDRF at the Partnering for Cures Conference
JDRF at the Partnering for Cures ConferenceJDRF at the Partnering for Cures Conference
JDRF at the Partnering for Cures Conference
TRAIN Central Station
 
IAVI's Integrated R&D Program: Accelerating AIDS vaccine development
IAVI's Integrated R&D Program: Accelerating AIDS vaccine developmentIAVI's Integrated R&D Program: Accelerating AIDS vaccine development
IAVI's Integrated R&D Program: Accelerating AIDS vaccine development
TRAIN Central Station
 
DNDi: New Drugs for Neglected Diseases; New Hope for Forgotten Patients
DNDi: New Drugs for Neglected Diseases; New Hope for Forgotten PatientsDNDi: New Drugs for Neglected Diseases; New Hope for Forgotten Patients
DNDi: New Drugs for Neglected Diseases; New Hope for Forgotten Patients
TRAIN Central Station
 
TB Alliance: Improving Treatments Against TB
TB Alliance: Improving Treatments Against TBTB Alliance: Improving Treatments Against TB
TB Alliance: Improving Treatments Against TB
TRAIN Central Station
 

More from TRAIN Central Station (14)

Valley of Death CAN Briefing Slides
Valley of Death CAN Briefing SlidesValley of Death CAN Briefing Slides
Valley of Death CAN Briefing Slides
 
BIO 2010 Partnering with Patients
BIO 2010 Partnering with PatientsBIO 2010 Partnering with Patients
BIO 2010 Partnering with Patients
 
BIO 2010 Partnering with Patients
BIO 2010 Partnering with PatientsBIO 2010 Partnering with Patients
BIO 2010 Partnering with Patients
 
Pharma Assets Portal
Pharma Assets PortalPharma Assets Portal
Pharma Assets Portal
 
Valley of Death Panel Slides at the Partnering for Cures Conference, December...
Valley of Death Panel Slides at the Partnering for Cures Conference, December...Valley of Death Panel Slides at the Partnering for Cures Conference, December...
Valley of Death Panel Slides at the Partnering for Cures Conference, December...
 
Progeria Research Foundation at Partnering for Cures
Progeria Research Foundation at Partnering for CuresProgeria Research Foundation at Partnering for Cures
Progeria Research Foundation at Partnering for Cures
 
PATH Malaria Vaccine Initiative
PATH Malaria Vaccine InitiativePATH Malaria Vaccine Initiative
PATH Malaria Vaccine Initiative
 
Life Raft Group: A New Model for Cancer Research
Life Raft Group: A New Model for Cancer ResearchLife Raft Group: A New Model for Cancer Research
Life Raft Group: A New Model for Cancer Research
 
Leukemia Lymphoma Society: An Invitation to Innovation
Leukemia Lymphoma Society: An Invitation to InnovationLeukemia Lymphoma Society: An Invitation to Innovation
Leukemia Lymphoma Society: An Invitation to Innovation
 
Susan G. Komen for the Cure Presentation at Partnering for Cures
Susan G. Komen for the Cure Presentation at Partnering for CuresSusan G. Komen for the Cure Presentation at Partnering for Cures
Susan G. Komen for the Cure Presentation at Partnering for Cures
 
JDRF at the Partnering for Cures Conference
JDRF at the Partnering for Cures ConferenceJDRF at the Partnering for Cures Conference
JDRF at the Partnering for Cures Conference
 
IAVI's Integrated R&D Program: Accelerating AIDS vaccine development
IAVI's Integrated R&D Program: Accelerating AIDS vaccine developmentIAVI's Integrated R&D Program: Accelerating AIDS vaccine development
IAVI's Integrated R&D Program: Accelerating AIDS vaccine development
 
DNDi: New Drugs for Neglected Diseases; New Hope for Forgotten Patients
DNDi: New Drugs for Neglected Diseases; New Hope for Forgotten PatientsDNDi: New Drugs for Neglected Diseases; New Hope for Forgotten Patients
DNDi: New Drugs for Neglected Diseases; New Hope for Forgotten Patients
 
TB Alliance: Improving Treatments Against TB
TB Alliance: Improving Treatments Against TBTB Alliance: Improving Treatments Against TB
TB Alliance: Improving Treatments Against TB
 

Recently uploaded

Exploring Alternatives- Why Laparoscopy Isn't Always Best for Hydrosalpinx.pptx
Exploring Alternatives- Why Laparoscopy Isn't Always Best for Hydrosalpinx.pptxExploring Alternatives- Why Laparoscopy Isn't Always Best for Hydrosalpinx.pptx
Exploring Alternatives- Why Laparoscopy Isn't Always Best for Hydrosalpinx.pptx
FFragrant
 
THE MANAGEMENT OF PROSTATE CANCER . pptx
THE MANAGEMENT OF PROSTATE CANCER . pptxTHE MANAGEMENT OF PROSTATE CANCER . pptx
THE MANAGEMENT OF PROSTATE CANCER . pptx
Bright Chipili
 
Managing Product Backlogs Tips for Prioritization and Organization by Joseph ...
Managing Product Backlogs Tips for Prioritization and Organization by Joseph ...Managing Product Backlogs Tips for Prioritization and Organization by Joseph ...
Managing Product Backlogs Tips for Prioritization and Organization by Joseph ...
JosephBozkaya
 
PCD Pharma Franchise For Gynae Products | Infertility Range - Sarthi Life Sci...
PCD Pharma Franchise For Gynae Products | Infertility Range - Sarthi Life Sci...PCD Pharma Franchise For Gynae Products | Infertility Range - Sarthi Life Sci...
PCD Pharma Franchise For Gynae Products | Infertility Range - Sarthi Life Sci...
Sarthi Life Sciences
 
Geriatric radiography.pptx Geriatric radiography.pptxGeriatric radiography.pptx
Geriatric radiography.pptx Geriatric radiography.pptxGeriatric radiography.pptxGeriatric radiography.pptx Geriatric radiography.pptxGeriatric radiography.pptx
Geriatric radiography.pptx Geriatric radiography.pptxGeriatric radiography.pptx
Dinesh Danny
 
selllllllllllllllllllllllllllllllllllllllllllllll.pptx
selllllllllllllllllllllllllllllllllllllllllllllll.pptxselllllllllllllllllllllllllllllllllllllllllllllll.pptx
selllllllllllllllllllllllllllllllllllllllllllllll.pptx
Joebest8
 
SA Gastro Cure(pancreatic cancer treatment in india).pptx
SA Gastro Cure(pancreatic cancer treatment in india).pptxSA Gastro Cure(pancreatic cancer treatment in india).pptx
SA Gastro Cure(pancreatic cancer treatment in india).pptx
VinothKumar70905
 
Perforation.pptx
Perforation.pptxPerforation.pptx
Perforation.pptx
Nandish Sannaiah
 
Mainstreaming #CleanLanguage in healthcare.pptx
Mainstreaming #CleanLanguage in healthcare.pptxMainstreaming #CleanLanguage in healthcare.pptx
Mainstreaming #CleanLanguage in healthcare.pptx
Judy Rees
 
POTENTIAL TARGET DISEASES FOR GENE THERAPY SOURAV.pptx
POTENTIAL TARGET DISEASES FOR GENE THERAPY SOURAV.pptxPOTENTIAL TARGET DISEASES FOR GENE THERAPY SOURAV.pptx
POTENTIAL TARGET DISEASES FOR GENE THERAPY SOURAV.pptx
souravpaul769171
 
Amygdala Medi-Trivia Quiz (Prelims) | FAQ 2024
Amygdala Medi-Trivia Quiz (Prelims) | FAQ 2024Amygdala Medi-Trivia Quiz (Prelims) | FAQ 2024
Amygdala Medi-Trivia Quiz (Prelims) | FAQ 2024
Anindya Das Adhikary
 
KUSTHA PPT .pdf KUSTHA definition, classification, and modern probable correl...
KUSTHA PPT .pdf KUSTHA definition, classification, and modern probable correl...KUSTHA PPT .pdf KUSTHA definition, classification, and modern probable correl...
KUSTHA PPT .pdf KUSTHA definition, classification, and modern probable correl...
DrMalathiVenketesham
 
Journal club presentation JC 28.5.24 edit.pptx
Journal club presentation JC 28.5.24 edit.pptxJournal club presentation JC 28.5.24 edit.pptx
Journal club presentation JC 28.5.24 edit.pptx
AdhyaDubey1
 
vaginal thrush presentation by Dr. Rewas Ali
vaginal thrush presentation by Dr. Rewas Alivaginal thrush presentation by Dr. Rewas Ali
vaginal thrush presentation by Dr. Rewas Ali
RewAs ALI
 
Top 10 Habits for Longevity [Biohacker Summit 2024]
Top 10 Habits for Longevity [Biohacker Summit 2024]Top 10 Habits for Longevity [Biohacker Summit 2024]
Top 10 Habits for Longevity [Biohacker Summit 2024]
Olli Sovijärvi
 
Care and Maintenance of Laboratory Equipment in Histotechnology.pptx
Care and Maintenance of Laboratory Equipment in Histotechnology.pptxCare and Maintenance of Laboratory Equipment in Histotechnology.pptx
Care and Maintenance of Laboratory Equipment in Histotechnology.pptx
Dr. Jagroop Singh
 
Approach to Head Injuiry, Intracranial Pressure Measurement and Management.pptx
Approach to Head Injuiry, Intracranial Pressure Measurement and Management.pptxApproach to Head Injuiry, Intracranial Pressure Measurement and Management.pptx
Approach to Head Injuiry, Intracranial Pressure Measurement and Management.pptx
Bipul Thakur
 
FUNCTIONAL DYSPEPSIA by Dr. Maryam Iqbal
FUNCTIONAL DYSPEPSIA by Dr. Maryam IqbalFUNCTIONAL DYSPEPSIA by Dr. Maryam Iqbal
FUNCTIONAL DYSPEPSIA by Dr. Maryam Iqbal
Zain Umar
 
Respiratory system at glance- Neonatology
Respiratory system at glance- NeonatologyRespiratory system at glance- Neonatology
Respiratory system at glance- Neonatology
Dr. Habibur Rahim
 
Hemodialysis: Chapter 8, Complications During Hemodialysis, Part 3 - Dr.Gawad
Hemodialysis: Chapter 8, Complications During Hemodialysis, Part 3 - Dr.GawadHemodialysis: Chapter 8, Complications During Hemodialysis, Part 3 - Dr.Gawad
Hemodialysis: Chapter 8, Complications During Hemodialysis, Part 3 - Dr.Gawad
NephroTube - Dr.Gawad
 

Recently uploaded (20)

Exploring Alternatives- Why Laparoscopy Isn't Always Best for Hydrosalpinx.pptx
Exploring Alternatives- Why Laparoscopy Isn't Always Best for Hydrosalpinx.pptxExploring Alternatives- Why Laparoscopy Isn't Always Best for Hydrosalpinx.pptx
Exploring Alternatives- Why Laparoscopy Isn't Always Best for Hydrosalpinx.pptx
 
THE MANAGEMENT OF PROSTATE CANCER . pptx
THE MANAGEMENT OF PROSTATE CANCER . pptxTHE MANAGEMENT OF PROSTATE CANCER . pptx
THE MANAGEMENT OF PROSTATE CANCER . pptx
 
Managing Product Backlogs Tips for Prioritization and Organization by Joseph ...
Managing Product Backlogs Tips for Prioritization and Organization by Joseph ...Managing Product Backlogs Tips for Prioritization and Organization by Joseph ...
Managing Product Backlogs Tips for Prioritization and Organization by Joseph ...
 
PCD Pharma Franchise For Gynae Products | Infertility Range - Sarthi Life Sci...
PCD Pharma Franchise For Gynae Products | Infertility Range - Sarthi Life Sci...PCD Pharma Franchise For Gynae Products | Infertility Range - Sarthi Life Sci...
PCD Pharma Franchise For Gynae Products | Infertility Range - Sarthi Life Sci...
 
Geriatric radiography.pptx Geriatric radiography.pptxGeriatric radiography.pptx
Geriatric radiography.pptx Geriatric radiography.pptxGeriatric radiography.pptxGeriatric radiography.pptx Geriatric radiography.pptxGeriatric radiography.pptx
Geriatric radiography.pptx Geriatric radiography.pptxGeriatric radiography.pptx
 
selllllllllllllllllllllllllllllllllllllllllllllll.pptx
selllllllllllllllllllllllllllllllllllllllllllllll.pptxselllllllllllllllllllllllllllllllllllllllllllllll.pptx
selllllllllllllllllllllllllllllllllllllllllllllll.pptx
 
SA Gastro Cure(pancreatic cancer treatment in india).pptx
SA Gastro Cure(pancreatic cancer treatment in india).pptxSA Gastro Cure(pancreatic cancer treatment in india).pptx
SA Gastro Cure(pancreatic cancer treatment in india).pptx
 
Perforation.pptx
Perforation.pptxPerforation.pptx
Perforation.pptx
 
Mainstreaming #CleanLanguage in healthcare.pptx
Mainstreaming #CleanLanguage in healthcare.pptxMainstreaming #CleanLanguage in healthcare.pptx
Mainstreaming #CleanLanguage in healthcare.pptx
 
POTENTIAL TARGET DISEASES FOR GENE THERAPY SOURAV.pptx
POTENTIAL TARGET DISEASES FOR GENE THERAPY SOURAV.pptxPOTENTIAL TARGET DISEASES FOR GENE THERAPY SOURAV.pptx
POTENTIAL TARGET DISEASES FOR GENE THERAPY SOURAV.pptx
 
Amygdala Medi-Trivia Quiz (Prelims) | FAQ 2024
Amygdala Medi-Trivia Quiz (Prelims) | FAQ 2024Amygdala Medi-Trivia Quiz (Prelims) | FAQ 2024
Amygdala Medi-Trivia Quiz (Prelims) | FAQ 2024
 
KUSTHA PPT .pdf KUSTHA definition, classification, and modern probable correl...
KUSTHA PPT .pdf KUSTHA definition, classification, and modern probable correl...KUSTHA PPT .pdf KUSTHA definition, classification, and modern probable correl...
KUSTHA PPT .pdf KUSTHA definition, classification, and modern probable correl...
 
Journal club presentation JC 28.5.24 edit.pptx
Journal club presentation JC 28.5.24 edit.pptxJournal club presentation JC 28.5.24 edit.pptx
Journal club presentation JC 28.5.24 edit.pptx
 
vaginal thrush presentation by Dr. Rewas Ali
vaginal thrush presentation by Dr. Rewas Alivaginal thrush presentation by Dr. Rewas Ali
vaginal thrush presentation by Dr. Rewas Ali
 
Top 10 Habits for Longevity [Biohacker Summit 2024]
Top 10 Habits for Longevity [Biohacker Summit 2024]Top 10 Habits for Longevity [Biohacker Summit 2024]
Top 10 Habits for Longevity [Biohacker Summit 2024]
 
Care and Maintenance of Laboratory Equipment in Histotechnology.pptx
Care and Maintenance of Laboratory Equipment in Histotechnology.pptxCare and Maintenance of Laboratory Equipment in Histotechnology.pptx
Care and Maintenance of Laboratory Equipment in Histotechnology.pptx
 
Approach to Head Injuiry, Intracranial Pressure Measurement and Management.pptx
Approach to Head Injuiry, Intracranial Pressure Measurement and Management.pptxApproach to Head Injuiry, Intracranial Pressure Measurement and Management.pptx
Approach to Head Injuiry, Intracranial Pressure Measurement and Management.pptx
 
FUNCTIONAL DYSPEPSIA by Dr. Maryam Iqbal
FUNCTIONAL DYSPEPSIA by Dr. Maryam IqbalFUNCTIONAL DYSPEPSIA by Dr. Maryam Iqbal
FUNCTIONAL DYSPEPSIA by Dr. Maryam Iqbal
 
Respiratory system at glance- Neonatology
Respiratory system at glance- NeonatologyRespiratory system at glance- Neonatology
Respiratory system at glance- Neonatology
 
Hemodialysis: Chapter 8, Complications During Hemodialysis, Part 3 - Dr.Gawad
Hemodialysis: Chapter 8, Complications During Hemodialysis, Part 3 - Dr.GawadHemodialysis: Chapter 8, Complications During Hemodialysis, Part 3 - Dr.Gawad
Hemodialysis: Chapter 8, Complications During Hemodialysis, Part 3 - Dr.Gawad
 

FasterCures Presentation at LifeFest 2008

  • 1. Kristin Schneeman Program Director September 12, 2008 “ What You Seed Is What You Get” Making Faster Cures the Central Organizing Principle of the Research Enterprise
  • 2. Saving lives by saving time Our mission is to identify and implement global solutions to accelerate the pace of discovery and clinical development of new therapies for the treatment of disease.
  • 3. FasterCures’ Blueprint for Change Research Leadership and Innovation The Redstone Acceleration and Innovation Network (TRAIN): Sharing best practices in funding and conducting innovative research Philanthropy Advisory Service: Develop a more transparent information marketplace to help philanthropists make informed investment decisions TRAIN-dustrial Relations: Facilitate partnerships between nonprofits and industry to help translate research into therapeutic breakthroughs
  • 4. FasterCures’ Blueprint for Change Research Tools and Resources Patients Helping Doctors BioBank Central Electronic health records Research Environment Advocacy for change at the FDA and NIH Intellectual property and technology transfer HIPAA reform
  • 5. “Entrepreneurs for Cures” What would your business model be if your bottom line were curing a disease?
  • 6. The High Costs of Business as Usual We’re spending a lot on treating disease: $2.1 trillion on healthcare in 2006 – more than $7000 per person We’re not spending much on curing disease: And productivity is falling: Sources: CMS, Research!America
  • 7. A New Central Organizing Principle Our current research infrastructure has led to great advances in knowledge of human health and disease; but it is not a good system for developing therapies for patients studying biology curing diseases
  • 8. The Translation Gap Basic research is the earliest stage of research, carried out for the advancement of knowledge, without necessarily any regard to its application to practical problems. Translational research is the process of applying ideas, insights, and discoveries generated through basic scientific inquiry to the treatment and prevention of human disease – the critical bridge between basic research and clinical research. Clinical research is research in human subjects aiming toward approved treatments for patients.
  • 9. Separating what we need to do in science and what we need to do in the culture of science to accelerate curing diseases
  • 10. TRAIN: You Are Not Alone The Redstone Acceleration and Innovation Network Collaborative, mission-driven, results-oriented, and strategic in their use of capital, these groups are motivated solely by moving promising therapies from the laboratory bench to the patient’s bedside as rapidly as possible – even those that do not directly fund therapy development.
  • 11. “ Venture Philanthropy” -> “Passion Capital” Strategic use of capital Building collaborations Streamlining the grantmaking process Sharing information “… patient groups with an entrepreneurial bent have become the drug industry’s new power brokers.” - Forbes , 9/15/08
  • 12. Nonprofits as “De-Riskers” Developing pre-clinical tools Targeting research to support translation Funding mechanisms that bring in industry Managing academic science Access to patient community New indications for existing drugs High-throughput screening of promising compounds Access to scientific expertise Advocating with FDA
  • 13. New Business Models to Accelerate Research More than $66 million in research funding since 2005 Actively supports more than 30 new treatments in development – 4 FDA-approved Partners include Vertex Pharmaceuticals, Parion Sciences, PTC Therapeutics, Inspire Pharmaceuticals, Gilead Sciences, Altus Pharmaceuticals Research Preclinical Phase 1 Phase 2 Phase 3 To Patients
  • 14. New Business Models to Accelerate Research Funded $126 million in research to date, two-thirds for translational research Funded testing of over 100 therapeutic targets for Parkinson’s Disease Partnership with Elan Corp. gives Elan first look at promising projects
  • 15. New Business Models to Accelerate Research Has raised $102 million to fund 70 labs worldwide 4 new treatments approved in 4 years 10 clinical trials facilitated by MMRF’s Research Consortium 30 MMRF-funded compounds now in preclinical studies and clinical trials
  • 16. Instead of following the money, lead the money.