1) Fires occur when the fire triad of fuel, oxidizer, and ignition source are present simultaneously.
2) Prevention focuses on keeping the elements of the fire triad separated through minimizing flammable materials and following safety guidelines.
3) Management of OR fires depends on the type of fire and may involve using fire extinguishers, blankets, or inert gases following the RACE protocol of rescuing patients, sounding alarms, confining the fire, and extinguishing it.
Oxygen Reduction System N2 FIREFIGHTER® ISOLCELL SPADiego Gasser
"Completely eliminating the fire hazard and safeguarding people, buildings and it's content is possible with Isolcell's N2 Firefighter oxygen depletion systems."
Oxygen Reduction System N2 FIREFIGHTER® ISOLCELL SPADiego Gasser
"Completely eliminating the fire hazard and safeguarding people, buildings and it's content is possible with Isolcell's N2 Firefighter oxygen depletion systems."
meaning of fire hazards, types of fire,fire triangle,classification of fire,precaution devices,fire extinguisher,types of fire extinguisher, reason of fire hazards,precaution taken in case of fire hazards......important points related to fire hazards..this is very helpful presentation.
Pressure Swing Adsorption (PSA) is a technology used to separate some gas species from a mixture of gases under pressure according to the species using molecular sieves desiccant.
meaning of fire hazards, types of fire,fire triangle,classification of fire,precaution devices,fire extinguisher,types of fire extinguisher, reason of fire hazards,precaution taken in case of fire hazards......important points related to fire hazards..this is very helpful presentation.
Pressure Swing Adsorption (PSA) is a technology used to separate some gas species from a mixture of gases under pressure according to the species using molecular sieves desiccant.
Acute scrotum is a general term referring to an emergency condition affecting the contents or the wall of the scrotum.
There are a number of conditions that present acutely, predominantly with pain and/or swelling
A careful and detailed history and examination, and in some cases, investigations allow differentiation between these diagnoses. A prompt diagnosis is essential as the patient may require urgent surgical intervention
Testicular torsion refers to twisting of the spermatic cord, causing ischaemia of the testicle.
Testicular torsion results from inadequate fixation of the testis to the tunica vaginalis producing ischemia from reduced arterial inflow and venous outflow obstruction.
The prevalence of testicular torsion in adult patients hospitalized with acute scrotal pain is approximately 25 to 50 percent
Ethanol (CH3CH2OH), or beverage alcohol, is a two-carbon alcohol
that is rapidly distributed in the body and brain. Ethanol alters many
neurochemical systems and has rewarding and addictive properties. It
is the oldest recreational drug and likely contributes to more morbidity,
mortality, and public health costs than all illicit drugs combined. The
5th edition of the Diagnostic and Statistical Manual of Mental Disorders
(DSM-5) integrates alcohol abuse and alcohol dependence into a single
disorder called alcohol use disorder (AUD), with mild, moderate,
and severe subclassifications (American Psychiatric Association, 2013).
In the DSM-5, all types of substance abuse and dependence have been
combined into a single substance use disorder (SUD) on a continuum
from mild to severe. A diagnosis of AUD requires that at least two of
the 11 DSM-5 behaviors be present within a 12-month period (mild
AUD: 2–3 criteria; moderate AUD: 4–5 criteria; severe AUD: 6–11 criteria).
The four main behavioral effects of AUD are impaired control over
drinking, negative social consequences, risky use, and altered physiological
effects (tolerance, withdrawal). This chapter presents an overview
of the prevalence and harmful consequences of AUD in the U.S.,
the systemic nature of the disease, neurocircuitry and stages of AUD,
comorbidities, fetal alcohol spectrum disorders, genetic risk factors, and
pharmacotherapies for AUD.
Flu Vaccine Alert in Bangalore Karnatakaaddon Scans
As flu season approaches, health officials in Bangalore, Karnataka, are urging residents to get their flu vaccinations. The seasonal flu, while common, can lead to severe health complications, particularly for vulnerable populations such as young children, the elderly, and those with underlying health conditions.
Dr. Vidisha Kumari, a leading epidemiologist in Bangalore, emphasizes the importance of getting vaccinated. "The flu vaccine is our best defense against the influenza virus. It not only protects individuals but also helps prevent the spread of the virus in our communities," he says.
This year, the flu season is expected to coincide with a potential increase in other respiratory illnesses. The Karnataka Health Department has launched an awareness campaign highlighting the significance of flu vaccinations. They have set up multiple vaccination centers across Bangalore, making it convenient for residents to receive their shots.
To encourage widespread vaccination, the government is also collaborating with local schools, workplaces, and community centers to facilitate vaccination drives. Special attention is being given to ensuring that the vaccine is accessible to all, including marginalized communities who may have limited access to healthcare.
Residents are reminded that the flu vaccine is safe and effective. Common side effects are mild and may include soreness at the injection site, mild fever, or muscle aches. These side effects are generally short-lived and far less severe than the flu itself.
Healthcare providers are also stressing the importance of continuing COVID-19 precautions. Wearing masks, practicing good hand hygiene, and maintaining social distancing are still crucial, especially in crowded places.
Protect yourself and your loved ones by getting vaccinated. Together, we can help keep Bangalore healthy and safe this flu season. For more information on vaccination centers and schedules, residents can visit the Karnataka Health Department’s official website or follow their social media pages.
Stay informed, stay safe, and get your flu shot today!
Couples presenting to the infertility clinic- Do they really have infertility...Sujoy Dasgupta
Dr Sujoy Dasgupta presented the study on "Couples presenting to the infertility clinic- Do they really have infertility? – The unexplored stories of non-consummation" in the 13th Congress of the Asia Pacific Initiative on Reproduction (ASPIRE 2024) at Manila on 24 May, 2024.
Lung Cancer: Artificial Intelligence, Synergetics, Complex System Analysis, S...Oleg Kshivets
RESULTS: Overall life span (LS) was 2252.1±1742.5 days and cumulative 5-year survival (5YS) reached 73.2%, 10 years – 64.8%, 20 years – 42.5%. 513 LCP lived more than 5 years (LS=3124.6±1525.6 days), 148 LCP – more than 10 years (LS=5054.4±1504.1 days).199 LCP died because of LC (LS=562.7±374.5 days). 5YS of LCP after bi/lobectomies was significantly superior in comparison with LCP after pneumonectomies (78.1% vs.63.7%, P=0.00001 by log-rank test). AT significantly improved 5YS (66.3% vs. 34.8%) (P=0.00000 by log-rank test) only for LCP with N1-2. Cox modeling displayed that 5YS of LCP significantly depended on: phase transition (PT) early-invasive LC in terms of synergetics, PT N0—N12, cell ratio factors (ratio between cancer cells- CC and blood cells subpopulations), G1-3, histology, glucose, AT, blood cell circuit, prothrombin index, heparin tolerance, recalcification time (P=0.000-0.038). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and PT early-invasive LC (rank=1), PT N0—N12 (rank=2), thrombocytes/CC (3), erythrocytes/CC (4), eosinophils/CC (5), healthy cells/CC (6), lymphocytes/CC (7), segmented neutrophils/CC (8), stick neutrophils/CC (9), monocytes/CC (10); leucocytes/CC (11). Correct prediction of 5YS was 100% by neural networks computing (area under ROC curve=1.0; error=0.0).
CONCLUSIONS: 5YS of LCP after radical procedures significantly depended on: 1) PT early-invasive cancer; 2) PT N0--N12; 3) cell ratio factors; 4) blood cell circuit; 5) biochemical factors; 6) hemostasis system; 7) AT; 8) LC characteristics; 9) LC cell dynamics; 10) surgery type: lobectomy/pneumonectomy; 11) anthropometric data. Optimal diagnosis and treatment strategies for LC are: 1) screening and early detection of LC; 2) availability of experienced thoracic surgeons because of complexity of radical procedures; 3) aggressive en block surgery and adequate lymph node dissection for completeness; 4) precise prediction; 5) adjuvant chemoimmunoradiotherapy for LCP with unfavorable prognosis.
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Ve...kevinkariuki227
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
New Drug Discovery and Development .....NEHA GUPTA
The "New Drug Discovery and Development" process involves the identification, design, testing, and manufacturing of novel pharmaceutical compounds with the aim of introducing new and improved treatments for various medical conditions. This comprehensive endeavor encompasses various stages, including target identification, preclinical studies, clinical trials, regulatory approval, and post-market surveillance. It involves multidisciplinary collaboration among scientists, researchers, clinicians, regulatory experts, and pharmaceutical companies to bring innovative therapies to market and address unmet medical needs.
New Directions in Targeted Therapeutic Approaches for Older Adults With Mantl...i3 Health
i3 Health is pleased to make the speaker slides from this activity available for use as a non-accredited self-study or teaching resource.
This slide deck presented by Dr. Kami Maddocks, Professor-Clinical in the Division of Hematology and
Associate Division Director for Ambulatory Operations
The Ohio State University Comprehensive Cancer Center, will provide insight into new directions in targeted therapeutic approaches for older adults with mantle cell lymphoma.
STATEMENT OF NEED
Mantle cell lymphoma (MCL) is a rare, aggressive B-cell non-Hodgkin lymphoma (NHL) accounting for 5% to 7% of all lymphomas. Its prognosis ranges from indolent disease that does not require treatment for years to very aggressive disease, which is associated with poor survival (Silkenstedt et al, 2021). Typically, MCL is diagnosed at advanced stage and in older patients who cannot tolerate intensive therapy (NCCN, 2022). Although recent advances have slightly increased remission rates, recurrence and relapse remain very common, leading to a median overall survival between 3 and 6 years (LLS, 2021). Though there are several effective options, progress is still needed towards establishing an accepted frontline approach for MCL (Castellino et al, 2022). Treatment selection and management of MCL are complicated by the heterogeneity of prognosis, advanced age and comorbidities of patients, and lack of an established standard approach for treatment, making it vital that clinicians be familiar with the latest research and advances in this area. In this activity chaired by Michael Wang, MD, Professor in the Department of Lymphoma & Myeloma at MD Anderson Cancer Center, expert faculty will discuss prognostic factors informing treatment, the promising results of recent trials in new therapeutic approaches, and the implications of treatment resistance in therapeutic selection for MCL.
Target Audience
Hematology/oncology fellows, attending faculty, and other health care professionals involved in the treatment of patients with mantle cell lymphoma (MCL).
Learning Objectives
1.) Identify clinical and biological prognostic factors that can guide treatment decision making for older adults with MCL
2.) Evaluate emerging data on targeted therapeutic approaches for treatment-naive and relapsed/refractory MCL and their applicability to older adults
3.) Assess mechanisms of resistance to targeted therapies for MCL and their implications for treatment selection
Prix Galien International 2024 Forum ProgramLevi Shapiro
June 20, 2024, Prix Galien International and Jerusalem Ethics Forum in ROME. Detailed agenda including panels:
- ADVANCES IN CARDIOLOGY: A NEW PARADIGM IS COMING
- WOMEN’S HEALTH: FERTILITY PRESERVATION
- WHAT’S NEW IN THE TREATMENT OF INFECTIOUS,
ONCOLOGICAL AND INFLAMMATORY SKIN DISEASES?
- ARTIFICIAL INTELLIGENCE AND ETHICS
- GENE THERAPY
- BEYOND BORDERS: GLOBAL INITIATIVES FOR DEMOCRATIZING LIFE SCIENCE TECHNOLOGIES AND PROMOTING ACCESS TO HEALTHCARE
- ETHICAL CHALLENGES IN LIFE SCIENCES
- Prix Galien International Awards Ceremony
3. -FIRE TRIAD
--Fuel
--Oxidizer
--Source of Heat and Ignition
These must be present simultaneously
and in correct proportions
SO
Fires can be prevented and controlled by
removing any one of these elements
6. Products of combustion
--Depend upon:
--Temperature of fire
--Nature
--Proportions of the fuel & oxidizer
--Complete combustion: water, CO2,
other oxides
--Incomplete combustion: variety of by
products
7. Products of combustion
--Specific combustion products: PVC, silastic,
plastics (produce acids such as HCl &
hydrogen sulphide, cyanides, CO & phenols)
Potentially hazardous
8. -
Pulmonary toxicity of
combustion products
Consumption of
oxygen by fire
Reduced oxygen availability
d/t CO
Products of combustion contd.
10. MOST EFFECTIVE METHOD
--Keep the elements of FIRE TRIAD
separated
-- Follow basic Laser & Electrical
safety guidelines
--Minimize presence of flammable materials
11. Sources of Heat & Ignition
Electrosurgical units
--Audible warning tones:- (shouldn’t be disabled)
--Foot switches:-should be assigned and
disconnected when not in use
--Placing probe in insulated, nonflammable Holster
12. Sources of Heat & Ignition
-Cardiac defibrillators
--Electrodes to make direct contact without
intervening wires, linen, clothing
--Alcohol or alcohol-soaked pads nitroglycerine
patches ointments should never be used as
conducting medium
13. Sources of Heat & Ignition
--Laser: Energy source; very high-power density
--Incidentally pressing the laser control trigger,
tissue damage outside the surgical site
– Drape fire
– Eye (patient or other medical staff)
– Endotracheal tube fires
14. Endotracheal tube fires
--Direct laser illumination
--Reflected laser light
--Incandescent particles of tissue
blown from the surgical site
15. Prevention
---Reduce the flammability of the
endotracheal tube
---Use of Laser resistant ET tubes
---Use Venturi ventilation
---Use intermittent apnea technique
16. Sources of Heat & Ignition
---Electrical fires in anesthetic monitors have been
reported
---NaCl contamination of the interior of monitors resulted
in electrical short circuits which led to over heating &
ignition of monitors
17. Fuel
--Flammable anesthetic agents
-- Flammable disinfecting & degreasing solutions:
alcohol & acetone, must evaporate & fumes have
eliminated before surgery begins
-- Surgical drapes & dressings free of disinfectants
18. -
Fuel
-Tissue contents such as bowel gas
-Contains: hydrogen + methane
-Laparoscopy: insufflation with air
-Colonoscopy
-Preventive measures
--Unprepared colon is discouraged
--Low residue diet
--Pre op fasting for 12 hrs
19. Fuel
--Electrosurgery in airway: Dangerous
--ET tubes, esophageal steth, nasogastric tubes
PVC inflammable with high oxygenconc.
--Preventive measures:
--Lowest power for cautery
--Bipolar cautery
--Helium- oxygen mixture
--Jet ventilation without tracheal intubation
--Laser resistant ET tubes
20. Fuel
-Forced air patient warming blankets: Once
ignited rapid combustion (fuel source:
drape material, oxidizer: forced air)
21. -Oxidizer
-Decrease escape of oxygen & nitrous
oxide
-Lowest inspired oxygen conc. That
ensures adequate oxygenation, to
minimize O2 accumulation
-Selective use of supplemental oxygen
-Avoid use of ESU in and around
trachea & pharynx
-Addition of inert gases (He) to O2
23. TYPES OF FIRE
-Class A: wood, paper, cloth &
most plastic
-Class B: flammable liquids &
grease
-Class C: fire involving electricity
24. Fire Blanket Water CO2 Dry
Chemical
Halon
Types of
Fire
Small class
A
Class
A/some B
Class B/C
Some A
Class
A/B/C
Class A/B/C
Mechanism Interrupts
Oxidation
Interrupts
Oxidation and
disperses heat
Interrupts
Oxidation and
disperses
Heat
Interrupts
Oxidation
Disperses
Heat
Interrupts
Oxidation,
disperses
Heat
Notes In Expensive
eg. Non-Toxic
Heavy bulky
devices, risk
of electric
shock
Heavy and
Bulky
devices
Leaves
Residue
Damages
equipments ?
Toxicity
Small, light
No residue /
Toxicity
25. Use of Fire Extinguishers
--PASS:
– Pull the Pin to activate
– Aim at the base of the fire
– Squeeze the trigger
– Sweep the extinguisher back & forth across
the base of fire
26. Fire safety education
--Activation of alarm & communication
system
--Location & use of fire fighting tools
--Management of small fire, to prevent spread
--Appropriate responses when fire
spread beyond control
27. Fire safety education
---When & how to evacuate a room, even when it is
crowded with equipments & people
---Appropriate routes to take for evacuation, esp
when smoke/ flames block normal entry/ exit
---Location of ‘safety zones’ inside & outside the
building where patients/ personnel can be
evacuated
