Explain how recombination increases the amount of genetic variation in offspring: Explain why it is not possible to have a recombination frequency of greater than 50% (half recombinant progeny): A second pair of Drosophila are mated. The female is Cucu YY (straight wing, gray body), while the male is Cucu yy (straight wing, yellow body). Assuming recombination, perform the cross and list the offspring genotypes and phenotypes. Solution Que-3: The recombination frequency is the measure of genetic linkage at different loci. The value of recombination frequency is 50% if the chromosomal genes are located at different regions on the different chromosome because of independent assortment. If the genes are located closely together on the same chromosome, then those genes considered as genetically linked; because they have not assorted independently due to \"crossing over\", then the recombination frequency value is less than 50%. Linked genes are due to linkage often do not obey Mendel\'s laws of inheritance such as independent assortment because of \"crossing over with reciprocal exchange of hereditary genetic material meticulously in between non-sister chromatids\" at the time of \"synapsis formation\" (propahse -I) in reduction division or meiosis 1. These events are leading to formation of gamete cells with complete different genotypically from diploid parent reproductive cell via meiosis finally induce \"genetic variation\" in phenotype due to \"fertilization\" events between sperm cells & ovum. The recombination of chromosomes enables meiosis process of cell division with the generation of novel recombinant nucleotide -sequences by crossing over during the cell division in both unicellular and multicellular species. Sometimes, double strand breaks in DNA during homologous chromosomal recombination may be produced due to exposure any harmful radiation finally may cause higher genetic variation via duplication followed by fertilization to form a phenotype with higher genetic variation Que-4: Crossing over is somewhat randomly distributed over the length of the chromosome because if the two genes are close together then it is very change to get exchange of chromosomal breaks therefore, if the two genes are located farther apart then there will be higher room for the exchange of genetic material with chromosomal breaks. Therefore, when two genetic are far apart on the same chromosome are more likely to have a crossover between them than two loci that are close together. This recombination frequency is considered as a measure of genetic linkage during the crossover of the homologous chromosomes. Linkage disequilibrium defined as the existence of alleles at different loci with the absence of genetic linkage between them even though there is no equilibrium with allelic frequencies independently. The recombination frequency is the measure of genetic linkage at different loci. The value of recombination frequency is 50% \"if the chromosomal genes are .