I need help with this one Question 18 of 18 Sapling Learning macmillan earning Integral membrane proteins have different characteristics and functions than peripheral membrane proteins. Sort the statements into those that are properties of integral membrane proteins and those that are properties of peripheral membrane proteins. Integral membrane proteins Peripheral membrane proteins can move laterally (sideways) in the hydrophobic part of the membrane found at the surface of the cell membrane reach through all or part of the membrane pump substances across the cell membrane Solution Integral membrane proteins ( intrinsic proteins) Peripheral membrane proteins, or extrinsic proteins Mainly found either fully or partially submerged in the phospholipids bilayer of the plasma membrane. They have hydrophobic side chains that interact with fatty acyl groups of the membrane phospholipids, thus anchoring the protein to the membrane. Integral proteins represent around 70% of plasma membrane proteins. Present at the surface ie on the innermost and outermost of phospholipids bilayer. These proteins are loosely bound to the plasma membrane either directly by interactions with polar heads of phospholipids bilayer or indirectly by interactions with integral proteins. These proteins constitute about 20-30 % of total membrane proteins. Reach through all or part of the membrane (Most of the integral proteins span the entire phospholipid bilayer -from the inner surface to the outer surface. These transmembrane proteins contain one or more membrane-spanning domains as well as domains, from four to several hundred residues long, extending into the aqueous medium on each side of the bilayer Pump substances across the cell membrane (Peripheral proteins at the cytosolic face of the plasma membrane include the cytoskeletal proteins spectrin and actin in erythrocytes and the enzyme protein kinase C. This enzyme shuttles between the cytosol and the cytosolic face of the plasma membrane and plays a role in signal transduction) Can move laterally (sideways) in the hydrophobic part of the membrane. Integral proteins are tightly bound and are directly interacting with the hydrophobic core of the plasma membrane Do not interact with the hydrophobic core in between two layers of phospholipids. Integral membrane proteins ( intrinsic proteins) Peripheral membrane proteins, or extrinsic proteins Mainly found either fully or partially submerged in the phospholipids bilayer of the plasma membrane. They have hydrophobic side chains that interact with fatty acyl groups of the membrane phospholipids, thus anchoring the protein to the membrane. Integral proteins represent around 70% of plasma membrane proteins. Present at the surface ie on the innermost and outermost of phospholipids bilayer. These proteins are loosely bound to the plasma membrane either directly by interactions with polar heads of phospholipids bilayer or indirectly by interactions with integral proteins. These pro.

1. I need help with this one Question 18 of 18 Sapling Learning macmillan earning Integral
membrane proteins have different characteristics and functions than peripheral membrane
proteins. Sort the statements into those that are properties of integral membrane proteins and
those that are properties of peripheral membrane proteins. Integral membrane proteins Peripheral
membrane proteins can move laterally (sideways) in the hydrophobic part of the membrane
found at the surface of the cell membrane reach through all or part of the membrane pump
substances across the cell membrane
Solution
Integral membrane proteins ( intrinsic proteins)
Peripheral membrane proteins, or extrinsic proteins
Mainly found either fully or partially submerged in the phospholipids bilayer of the plasma
membrane. They have hydrophobic side chains that interact with fatty acyl groups of the
membrane phospholipids, thus anchoring the protein to the membrane.
Integral proteins represent around 70% of plasma membrane proteins.
Present at the surface ie on the innermost and outermost of phospholipids bilayer. These proteins
are loosely bound to the plasma membrane either directly by interactions with polar heads of
phospholipids bilayer or indirectly by interactions with integral proteins. These proteins
constitute about 20-30 % of total membrane proteins.
Reach through all or part of the membrane (Most of the integral proteins span the entire
phospholipid bilayer -from the inner surface to the outer surface. These transmembrane proteins
contain one or more membrane-spanning domains as well as domains, from four to several
hundred residues long, extending into the aqueous medium on each side of the bilayer
Pump substances across the cell membrane (Peripheral proteins at the cytosolic face of the
plasma membrane include the cytoskeletal proteins spectrin and actin in erythrocytes and the
enzyme protein kinase C. This enzyme shuttles between the cytosol and the cytosolic face of the
plasma membrane and plays a role in signal transduction)
Can move laterally (sideways) in the hydrophobic part of the membrane. Integral proteins are
tightly bound and are directly interacting with the hydrophobic core of the plasma membrane
Do not interact with the hydrophobic core in between two layers of phospholipids.
Integral membrane proteins ( intrinsic proteins)
Peripheral membrane proteins, or extrinsic proteins
Mainly found either fully or partially submerged in the phospholipids bilayer of the plasma
membrane. They have hydrophobic side chains that interact with fatty acyl groups of the

2. membrane phospholipids, thus anchoring the protein to the membrane.
Integral proteins represent around 70% of plasma membrane proteins.
Present at the surface ie on the innermost and outermost of phospholipids bilayer. These proteins
are loosely bound to the plasma membrane either directly by interactions with polar heads of
phospholipids bilayer or indirectly by interactions with integral proteins. These proteins
constitute about 20-30 % of total membrane proteins.
Reach through all or part of the membrane (Most of the integral proteins span the entire
phospholipid bilayer -from the inner surface to the outer surface. These transmembrane proteins
contain one or more membrane-spanning domains as well as domains, from four to several
hundred residues long, extending into the aqueous medium on each side of the bilayer
Pump substances across the cell membrane (Peripheral proteins at the cytosolic face of the
plasma membrane include the cytoskeletal proteins spectrin and actin in erythrocytes and the
enzyme protein kinase C. This enzyme shuttles between the cytosol and the cytosolic face of the
plasma membrane and plays a role in signal transduction)
Can move laterally (sideways) in the hydrophobic part of the membrane. Integral proteins are
tightly bound and are directly interacting with the hydrophobic core of the plasma membrane
Do not interact with the hydrophobic core in between two layers of phospholipids.