This document provides guidance on conducting exercises to test emergency preparedness and response plans. It outlines the objectives, key concepts, and process for planning drills and tabletop exercises. The objectives are to integrate and test plans through training, exercises, and evaluation in order to identify weaknesses and areas for improvement. Key steps include forming a planning team, defining goals and scenarios, inviting participants, facilitating the exercise, and conducting an evaluation and after-action review to develop an improvement plan. Guidance is provided on conducting both operation-based drills and discussion-based tabletop exercises, including templates for an exercise plan and evaluation questions.