This document provides an overview of the Epidemiology Unit at Columbia University for the 2011 academic year. It is led by Dr. Steven Shea and introduces students to epidemiology and clinical epidemiology. The goal is to help students interpret published epidemiological studies and clinical trials. Students will learn how to measure disease burden, identify causes of disease, and evaluate diagnostic tests and clinical trials. The primary textbook is Epidemiology by Leon Gordis and students will analyze research articles. Attendance at small group sessions is required to discuss assigned readings. The final exam will evaluate students' ability to critically interpret epidemiological data from journal articles.