This document summarizes two presentations about how real-time location systems (RTLS) can enhance safety and quality initiatives in healthcare settings. The first presentation describes how Eastern Maine Medical Center's cancer care center uses RTLS to improve patient flow, ensure timely treatments, locate family members, and facilitate reporting. Benefits included improved patient satisfaction, treatment efficiency and safety, staff satisfaction, and cost savings. The second presentation explains how Western Maryland Health System's behavioral health unit utilizes RTLS for staff panic buttons, patient elopement alerts, and suicide precaution rounding to improve staff safety, response efficiency, and elopement prevention. Both case studies demonstrated enhanced safety, treatment quality, and operational benefits through RTLS automation and location-based