This document discusses using an ant colony technique called Ant Colony System (ACS) to optimize the facility layout of a manufacturing plant. ACS was inspired by how real ants find food sources and build colonies. The research applies ACS to optimize the positions of machines and routing of parts in an electrical motor factory. Results showed ACS provided a flexible, fast solution that reduced the distance parts traveled in the plant by 500 meters, a reduction of 0.625. ACS is presented as an effective advanced intelligent technique for modifying a production process through facility layout optimization.