The endocrine system is made up of glands that produce hormones and regulate bodily functions. It includes the hypothalamus and pituitary gland in the brain, along with the thyroid, parathyroid, adrenal glands, pancreas, ovaries and testes. These glands secrete hormones that control growth and development, metabolism, sexual function, reproduction, sleep, and mood. Disruptions to the endocrine system can cause diabetes, thyroid disorders, and other health issues.