Endemic goiter is a thyroid enlargement caused primarily by dietary iodine deficiency, prevalent in areas where more than 5-10% of the population is affected. The condition arises when low iodine intake prompts excessive secretion of thyroid-stimulating hormone by the pituitary gland, leading to thyroid growth. Prevention strategies include the use of iodized salt, seafood, and iodinated oil, which have proven effective in reducing iodine deficiency globally.